NO164242C - Fremgangsmaate for fremstilling av pyrido-imidazo-rifamycin-derivater. - Google Patents

Fremgangsmaate for fremstilling av pyrido-imidazo-rifamycin-derivater.

Info

Publication number
NO164242C
NO164242C NO851921A NO851921A NO164242C NO 164242 C NO164242 C NO 164242C NO 851921 A NO851921 A NO 851921A NO 851921 A NO851921 A NO 851921A NO 164242 C NO164242 C NO 164242C
Authority
NO
Norway
Prior art keywords
imidazo
procedure
rifamycin derivatives
preparing pyrido
pyrido
Prior art date
Application number
NO851921A
Other languages
English (en)
Norwegian (no)
Other versions
NO164242B (no
NO851921L (no
Inventor
Vincenzo Cannata
Egidio Marchi
Gian Franco Tamagnone
Silvano Piani
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of NO851921L publication Critical patent/NO851921L/no
Publication of NO164242B publication Critical patent/NO164242B/no
Publication of NO164242C publication Critical patent/NO164242C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO851921A 1984-05-15 1985-05-14 Fremgangsmaate for fremstilling av pyrido-imidazo-rifamycin-derivater. NO164242C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03463/84A IT1199374B (it) 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine

Publications (3)

Publication Number Publication Date
NO851921L NO851921L (no) 1985-11-18
NO164242B NO164242B (no) 1990-06-05
NO164242C true NO164242C (no) 1990-09-12

Family

ID=11107845

Family Applications (1)

Application Number Title Priority Date Filing Date
NO851921A NO164242C (no) 1984-05-15 1985-05-14 Fremgangsmaate for fremstilling av pyrido-imidazo-rifamycin-derivater.

Country Status (18)

Country Link
US (1) US4557866A (pm)
EP (1) EP0161534B1 (pm)
JP (1) JPS60252483A (pm)
AR (1) AR241913A1 (pm)
AT (1) ATE46512T1 (pm)
AU (1) AU568934B2 (pm)
CA (1) CA1215708A (pm)
DE (1) DE3573120D1 (pm)
DK (1) DK162647C (pm)
ES (1) ES8603489A1 (pm)
FI (1) FI81101C (pm)
GR (1) GR851144B (pm)
IE (1) IE58392B1 (pm)
IT (1) IT1199374B (pm)
NO (1) NO164242C (pm)
PH (1) PH22007A (pm)
PT (1) PT80446B (pm)
ZA (1) ZA852971B (pm)

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US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
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ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7902206B2 (en) 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US7906542B2 (en) 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
PL1698630T3 (pl) * 2005-03-03 2014-12-31 Alfasigma Spa Nowe postacie polimorficzne rifaksyminy,sposoby ich wytwarzania i ich zastosowanie w preparatach leczniczych
ITBO20050123A1 (it) * 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
AU2007223881B2 (en) 2006-03-09 2014-01-09 Alan Safdi Rifaximin anti-rectal dysfunction preparation
HUE025306T2 (hu) 2006-08-02 2016-01-28 Salix Pharmaceuticals Inc Sugárterápia által okozott bélgyulladás kezelésére irányuló módszer
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
EP2069363B1 (en) * 2006-09-22 2013-03-20 Cipla Ltd. Rifaximin in an amorphous form
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
US7709634B2 (en) 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
GEP20135898B (en) 2008-02-25 2013-08-12 Salix Pharmaceuticals Ltd Rifaximin forms and usage
US8486956B2 (en) * 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
WO2009108814A1 (en) 2008-02-26 2009-09-03 Salix Pharmaceuticals, Ltd. Methods for treating bowel diseases
CA2723752A1 (en) 2008-05-07 2009-11-12 Salix Pharmaceuticals, Ltd. Methods of treating bowel disease by administering a bowel cleanser and an antibiotic
CN101585843B (zh) * 2008-05-21 2011-07-06 重庆赛诺生物药业股份有限公司 一种利福昔明的制备工艺
US7928115B2 (en) * 2008-10-02 2011-04-19 Salix Pharmaceuticals, Ltd. Methods of treating travelers diarrhea and hepatic encephalopathy
US20110035232A1 (en) 2008-10-02 2011-02-10 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
AU2009298389C1 (en) * 2008-10-02 2016-04-28 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
US12285414B2 (en) 2008-10-02 2025-04-29 Salix Pharmaceuticals, Inc. Methods of treating hepatic encephalopathy
EP2355805B1 (en) 2008-12-10 2019-02-13 Cipla Limited Rifaximin complexes
IT1397617B1 (it) 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
RU2540513C2 (ru) 2009-06-02 2015-02-10 Саликс Фармасьютикалз, Лтд. Способы лечения печеночной энцефалопатии
JP2013504597A (ja) 2009-09-13 2013-02-07 サリックス ファーマスーティカルズ,リミテッド 過敏性腸症候群(ibs)の治療方法
CN102724960A (zh) 2009-11-23 2012-10-10 希普拉有限公司 局部泡沫组合物
US8952159B2 (en) 2009-12-28 2015-02-10 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
JP5896380B2 (ja) 2010-02-18 2016-03-30 サリックス ファーマスーティカルズ,リミテッド 感染症を治療するための方法
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
WO2011156897A2 (en) * 2010-06-16 2011-12-22 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
PH12013500082B1 (en) 2010-07-12 2019-06-28 Salix Pharmaceuticals Ltd Formulations of rifaximin and uses thereof
US8759513B2 (en) 2010-09-13 2014-06-24 Sequent Scientific Limited Polymorphic form of rifaximin and process for its preparation
MX350448B (es) 2011-02-11 2017-09-07 Salix Pharmaceuticals Ltd Formas de rifaximina y usos de las mismas.
EP2705042A1 (en) 2011-05-02 2014-03-12 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
WO2012155981A1 (en) 2011-05-19 2012-11-22 Friulchem Spa New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
AU2012332211B2 (en) 2011-11-02 2016-11-24 Salix Pharmaceuticals, Ltd. Methods for treating irritable bowel syndrome (IBS) and infections
US9359374B2 (en) 2012-06-13 2016-06-07 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
WO2014140988A1 (en) 2013-03-15 2014-09-18 Alfa Wassermann S.P.A. Rifaximin for use in the treating of vaginal infections.
EP2971062A2 (en) 2013-03-15 2016-01-20 ALFA WASSERMANN S.p.A. Method for diagnosing vaginal infections
EA032705B1 (ru) 2013-04-12 2019-07-31 Альфасигма С.П.А. Способ лечения или предупреждения энтеропатии
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
ITMI20131307A1 (it) 2013-08-02 2015-02-02 A M S A Anonima Materie Sint & Affini S P A Processo per la preparazione di refaximina k
CN103509038B (zh) * 2013-09-30 2016-01-20 浙江思贤制药有限公司 一种新晶型利福昔明ζ及其制备方法
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
CA2947962C (en) 2014-05-04 2024-01-16 Salix Pharmaceuticals, Inc. Ibs microbiota and uses thereof
PT3546464T (pt) 2014-05-12 2020-08-05 Alfasigma Spa Preparação e utilização da forma cristalina tau de rifaximina solvatada com degme
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
KR20230023043A (ko) 2016-09-30 2023-02-16 샐릭스 파마슈티컬스 인코포레이티드 리팍시민의 고체 분산물 형태
RU2020102511A (ru) * 2017-06-26 2021-07-27 Биофер С.П.А. Соединения пиридо-имидазо рифамицина в качестве антибактериального средства

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1154655B (it) * 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Also Published As

Publication number Publication date
PH22007A (en) 1988-05-02
AR241913A1 (es) 1993-01-29
FI81101C (fi) 1990-09-10
DK162647C (da) 1992-04-13
EP0161534B1 (en) 1989-09-20
NO164242B (no) 1990-06-05
ZA852971B (en) 1985-12-24
DK214685D0 (da) 1985-05-14
JPH0469634B2 (pm) 1992-11-06
IT1199374B (it) 1988-12-30
ES543115A0 (es) 1986-01-01
IE58392B1 (en) 1993-09-08
GR851144B (pm) 1985-11-25
CA1215708A (en) 1986-12-23
PT80446A (en) 1985-06-01
DK214685A (da) 1985-11-16
AU4251585A (en) 1985-11-21
NO851921L (no) 1985-11-18
IT8403463A0 (it) 1984-05-15
PT80446B (pt) 1987-11-11
US4557866A (en) 1985-12-10
AU568934B2 (en) 1988-01-14
IE851191L (en) 1985-11-15
ATE46512T1 (de) 1989-10-15
FI851907L (fi) 1985-11-16
FI851907A0 (fi) 1985-05-14
DE3573120D1 (en) 1989-10-26
JPS60252483A (ja) 1985-12-13
EP0161534A2 (en) 1985-11-21
ES8603489A1 (es) 1986-01-01
EP0161534A3 (en) 1987-03-04
FI81101B (fi) 1990-05-31
DK162647B (da) 1991-11-25

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