NO885435L - Fremgangsmaate for fremstilling av benzotiazepinderivater. - Google Patents

Fremgangsmaate for fremstilling av benzotiazepinderivater.

Info

Publication number
NO885435L
NO885435L NO88885435A NO885435A NO885435L NO 885435 L NO885435 L NO 885435L NO 88885435 A NO88885435 A NO 88885435A NO 885435 A NO885435 A NO 885435A NO 885435 L NO885435 L NO 885435L
Authority
NO
Norway
Prior art keywords
benzotiazepine
derivatives
preparing
procedure
preparing benzotiazepine
Prior art date
Application number
NO88885435A
Other languages
English (en)
Other versions
NO167802B (no
NO167802C (no
NO885435D0 (no
Inventor
Alistair Lochead
Jean-Claude Muller
Christian Hoornaert
Colombe Denys
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO885435D0 publication Critical patent/NO885435D0/no
Publication of NO885435L publication Critical patent/NO885435L/no
Publication of NO167802B publication Critical patent/NO167802B/no
Publication of NO167802C publication Critical patent/NO167802C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO885435A 1987-12-08 1988-12-07 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepinderivater. NO167802C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8717044A FR2624117B1 (fr) 1987-12-08 1987-12-08 Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique

Publications (4)

Publication Number Publication Date
NO885435D0 NO885435D0 (no) 1988-12-07
NO885435L true NO885435L (no) 1989-06-09
NO167802B NO167802B (no) 1991-09-02
NO167802C NO167802C (no) 1991-12-11

Family

ID=9357609

Family Applications (1)

Application Number Title Priority Date Filing Date
NO885435A NO167802C (no) 1987-12-08 1988-12-07 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepinderivater.

Country Status (13)

Country Link
EP (2) EP0320362A1 (no)
JP (2) JPH01190674A (no)
KR (1) KR890009901A (no)
AU (1) AU609681B2 (no)
DK (1) DK681088A (no)
FI (1) FI885670A (no)
FR (1) FR2624117B1 (no)
HU (1) HU201538B (no)
IL (1) IL88608A0 (no)
NO (1) NO167802C (no)
NZ (1) NZ227235A (no)
PT (1) PT89182A (no)
ZA (1) ZA889169B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630109B1 (fr) * 1988-04-19 1991-11-29 Synthelabo Derives de ((n-(amino-2 oxo-2 ethyl)methylamino)-2 ethyl)-5 hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
US4963545A (en) * 1988-05-24 1990-10-16 Marion Laboratories, Inc. Benzothiazepine anti-seizure method
US5134139A (en) * 1989-08-31 1992-07-28 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and preparation thereof
FR2653122B1 (fr) * 1989-10-17 1994-04-15 Synthelabo Derives de 5-[2-[[2-amino-2-oxoethyl]methylamino]ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5(5h)-benzothiazepine-4-one, leur preparation et leur application en therapeutique.
CA2030159A1 (en) * 1989-11-22 1991-05-23 Nahed K. Ahmed Anti-cancer drug potentiators
CA2030160A1 (en) * 1989-11-22 1991-05-23 Nahed K. Ahmed Benzothiazepine metastasis treatment
FR2670785B1 (fr) * 1990-12-20 1993-07-09 Synthelabo Derives de (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique.
ES2118292T3 (es) * 1994-09-16 1998-09-16 Orion Corp Fermion Metodo para la preparacion de 3-hidroxi-5-(2-dimetilamino)-etil)-2,3-dihidro-4-(metoxifenil)-1,5-benzotiazepin-4(5h)-ona y uso del producto para elaborar compuestos farmaceuticamente activos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3119874A1 (de) * 1981-05-19 1982-12-09 Dr. Karl Thomae Gmbh, 7950 Biberach "benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel"
US4594342A (en) * 1984-04-10 1986-06-10 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivative
US4585768A (en) * 1984-04-10 1986-04-29 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and processes for preparing the same
US4729994A (en) * 1986-08-20 1988-03-08 Mcneilab, Inc. Benzothiazepine vasodilators having aralkyl substitution
ES2038668T3 (es) * 1986-08-20 1993-08-01 Mcneilab, Inc. Vasodilatadores de benzotiazepina dotados de sustitucion aralquilica.
FR2630109B1 (fr) * 1988-04-19 1991-11-29 Synthelabo Derives de ((n-(amino-2 oxo-2 ethyl)methylamino)-2 ethyl)-5 hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
EP0320362A1 (fr) 1989-06-14
KR890009901A (ko) 1989-08-04
AU2659588A (en) 1989-06-08
FR2624117B1 (fr) 1991-02-22
HUT50797A (en) 1990-03-28
HU201538B (en) 1990-11-28
FR2624117A1 (fr) 1989-06-09
IL88608A0 (en) 1989-07-31
EP0320361A1 (fr) 1989-06-14
DK681088D0 (da) 1988-12-07
NO167802B (no) 1991-09-02
PT89182A (pt) 1989-12-29
NO167802C (no) 1991-12-11
JPH01190632A (ja) 1989-07-31
FI885670A (fi) 1989-06-09
NZ227235A (en) 1990-06-26
JPH01190674A (ja) 1989-07-31
DK681088A (da) 1989-06-09
ZA889169B (en) 1990-05-30
FI885670A0 (fi) 1988-12-07
NO885435D0 (no) 1988-12-07
AU609681B2 (en) 1991-05-02

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