FI851907L - Nytt foerfarande foer syntetisering av pyridoimidazorifamyciner. - Google Patents

Nytt foerfarande foer syntetisering av pyridoimidazorifamyciner.

Info

Publication number
FI851907L
FI851907L FI851907A FI851907A FI851907L FI 851907 L FI851907 L FI 851907L FI 851907 A FI851907 A FI 851907A FI 851907 A FI851907 A FI 851907A FI 851907 L FI851907 L FI 851907L
Authority
FI
Finland
Prior art keywords
syntetisering
pyridoimidazorifamyciner
now
foerfarande foer
foerfarande
Prior art date
Application number
FI851907A
Other languages
English (en)
Other versions
FI81101C (fi
FI851907A0 (fi
FI81101B (fi
Inventor
Vincenzo Cannata
Gian Franco Tamagnone
Silvano Piani
Egidio Marchi
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of FI851907A0 publication Critical patent/FI851907A0/fi
Publication of FI851907L publication Critical patent/FI851907L/fi
Application granted granted Critical
Publication of FI81101B publication Critical patent/FI81101B/fi
Publication of FI81101C publication Critical patent/FI81101C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI851907A 1984-05-15 1985-05-14 Nytt foerfarande foer syntetisering av pyridoimidazorifamyciner. FI81101C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT346384 1984-05-15
IT03463/84A IT1199374B (it) 1984-05-15 1984-05-15 Processo per la preparazione di pirido-imidazo-rifamicine

Publications (4)

Publication Number Publication Date
FI851907A0 FI851907A0 (fi) 1985-05-14
FI851907L true FI851907L (fi) 1985-11-16
FI81101B FI81101B (fi) 1990-05-31
FI81101C FI81101C (fi) 1990-09-10

Family

ID=11107845

Family Applications (1)

Application Number Title Priority Date Filing Date
FI851907A FI81101C (fi) 1984-05-15 1985-05-14 Nytt foerfarande foer syntetisering av pyridoimidazorifamyciner.

Country Status (18)

Country Link
US (1) US4557866A (fi)
EP (1) EP0161534B1 (fi)
JP (1) JPS60252483A (fi)
AR (1) AR241913A1 (fi)
AT (1) ATE46512T1 (fi)
AU (1) AU568934B2 (fi)
CA (1) CA1215708A (fi)
DE (1) DE3573120D1 (fi)
DK (1) DK162647C (fi)
ES (1) ES8603489A1 (fi)
FI (1) FI81101C (fi)
GR (1) GR851144B (fi)
IE (1) IE58392B1 (fi)
IT (1) IT1199374B (fi)
NO (1) NO164242C (fi)
PH (1) PH22007A (fi)
PT (1) PT80446B (fi)
ZA (1) ZA852971B (fi)

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US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
AU2002364162A1 (en) * 2001-12-13 2003-06-30 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US7906542B2 (en) 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
ITMI20032144A1 (it) 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7923553B2 (en) 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US7902206B2 (en) 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
ES2522895T3 (es) * 2005-03-03 2014-11-19 Alfa Wassermann S.P.A. Nuevas formas polimorfas de rifaximina, procedimientos para su producción y uso de las mismas en preparados medicinales
ITBO20050123A1 (it) 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
MX2008011305A (es) 2006-03-09 2009-02-10 Salix Pharmaceuticals Inc Preparacion anti-disfunsion rectal con rifaximina.
WO2008016708A2 (en) 2006-08-02 2008-02-07 Salix Pharmaceuticals, Inc. Methods for treatment of radiation enteritis
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
KR101667534B1 (ko) * 2006-09-22 2016-10-19 씨아이피엘에이 엘티디. 리팍시민
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
US7709634B2 (en) 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
CN104650114A (zh) 2008-02-25 2015-05-27 萨利克斯药品有限公司 利福昔明的多种形式及其用途
AU2009219240B2 (en) 2008-02-26 2014-10-16 Salix Pharmaceuticals, Ltd. Methods for treating bowel diseases
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
DK2294012T3 (da) 2008-05-07 2014-10-06 Salix Pharmaceuticals Ltd Administration af et tarmrensemiddel og et antibiotika til behandlingen af tarmsygdom
CN101585843B (zh) * 2008-05-21 2011-07-06 重庆赛诺生物药业股份有限公司 一种利福昔明的制备工艺
US7928115B2 (en) 2008-10-02 2011-04-19 Salix Pharmaceuticals, Ltd. Methods of treating travelers diarrhea and hepatic encephalopathy
BRPI0920465A2 (pt) 2008-10-02 2018-03-20 Salix Pharmaceuticals, Inc. metodo de tratamento de encefalopatia hepática
US20110035232A1 (en) 2008-10-02 2011-02-10 Salix Pharmaceuticals, Ltd. Methods of treating hepatic encephalopathy
WO2010067072A1 (en) 2008-12-10 2010-06-17 Cipla Limited Rifaximin complexes
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
KR20120025578A (ko) 2009-06-02 2012-03-15 샐릭스 파마슈티컬스 리미티드 간성 뇌병증의 치료방법
CN102596250A (zh) 2009-09-13 2012-07-18 萨利克斯药品有限公司 治疗肠易激综合征(ibs)的方法
EP2503989A2 (en) 2009-11-23 2012-10-03 Cipla Limited Topical foam composition
US8952159B2 (en) 2009-12-28 2015-02-10 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
AU2011218129A1 (en) 2010-02-18 2012-08-23 Board Of Regents Of The University Of Texas System Methods for treating infection
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
EP2582707A4 (en) * 2010-06-16 2014-01-08 Apotex Pharmachem Inc POLYMORPHIC FORMS OF RIFAXIMINE
CN103228662B (zh) 2010-07-12 2016-08-10 萨利克斯药品有限公司 利福昔明的制剂及其用途
WO2012035544A2 (en) 2010-09-13 2012-03-22 Sequent Scientific Ltd. A novel polymorphic form of rifaximin and process for its preparation
US8735419B2 (en) 2011-02-11 2014-05-27 Salix Pharmaceuticals, Ltd. Forms of rifaximin and uses thereof
AU2012251385A1 (en) 2011-05-02 2013-11-21 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
WO2012155981A1 (en) 2011-05-19 2012-11-22 Friulchem Spa New process for the synthesis of rifaximin and a new pseudo-crystalline form of rifaximin obtained thereby
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
EP2773205B1 (en) 2011-11-02 2024-05-22 Salix Pharmaceuticals, Inc. Rifaximin for retreating diarrhea-predominant irritable bowel syndrome
CA2876737A1 (en) 2012-06-13 2013-12-19 Apotex Pharmachem Inc. Polymorphic forms of rifaximin
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
US20160047819A1 (en) 2013-03-15 2016-02-18 Alfa Wassermann S.P.A. Method for diagnosing vaginal infections
EP2968283A1 (en) 2013-03-15 2016-01-20 ALFA WASSERMANN S.p.A. Rifaximin for use in the treating of vaginal infections.
PT2983647T (pt) 2013-04-12 2020-11-09 Alfasigma Spa Administração de aine e composições, métodos e sistemas relacionados
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
ITMI20131307A1 (it) 2013-08-02 2015-02-02 A M S A Anonima Materie Sint & Affini S P A Processo per la preparazione di refaximina k
CN103509038B (zh) * 2013-09-30 2016-01-20 浙江思贤制药有限公司 一种新晶型利福昔明ζ及其制备方法
EP2927235B1 (en) 2014-03-31 2017-02-08 Euticals S.P.A. Polymorphic mixture of rifaximin and its use for the preparation of solid formulations
CA2947962C (en) 2014-05-04 2024-01-16 Salix Pharmaceuticals, Inc. Ibs microbiota and uses thereof
WO2015173697A1 (en) 2014-05-12 2015-11-19 Alfa Wassermann S.P.A. New solvated crystal form of rifaximin, production, compositions and uses thereof
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
EP4137132A1 (en) 2016-09-30 2023-02-22 Salix Pharmaceuticals, Inc. Solid dispersion forms of rifaximin
MX2019015681A (es) * 2017-06-26 2020-02-26 Biofer Spa Derivados de pirido-imidazo rifamicina como agente antibacteriano.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1154655B (it) * 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Also Published As

Publication number Publication date
JPS60252483A (ja) 1985-12-13
IE58392B1 (en) 1993-09-08
AU568934B2 (en) 1988-01-14
AU4251585A (en) 1985-11-21
DK162647C (da) 1992-04-13
NO164242C (no) 1990-09-12
NO851921L (no) 1985-11-18
FI81101C (fi) 1990-09-10
PT80446B (pt) 1987-11-11
US4557866A (en) 1985-12-10
AR241913A1 (es) 1993-01-29
NO164242B (no) 1990-06-05
ES543115A0 (es) 1986-01-01
JPH0469634B2 (fi) 1992-11-06
EP0161534A2 (en) 1985-11-21
IT8403463A0 (it) 1984-05-15
IE851191L (en) 1985-11-15
ES8603489A1 (es) 1986-01-01
FI851907A0 (fi) 1985-05-14
DE3573120D1 (en) 1989-10-26
PT80446A (en) 1985-06-01
PH22007A (en) 1988-05-02
EP0161534A3 (en) 1987-03-04
DK162647B (da) 1991-11-25
FI81101B (fi) 1990-05-31
EP0161534B1 (en) 1989-09-20
GR851144B (fi) 1985-11-25
CA1215708A (en) 1986-12-23
DK214685D0 (da) 1985-05-14
ZA852971B (en) 1985-12-24
IT1199374B (it) 1988-12-30
ATE46512T1 (de) 1989-10-15
DK214685A (da) 1985-11-16

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: ALFA FARMACEUTICI S.P.A.

MA Patent expired