NO161262C - Analogifremgangsm te for fremstilling av terapeutisk aktive s- adenosyl-l-metionin (sam) salter. - Google Patents

Analogifremgangsm te for fremstilling av terapeutisk aktive s- adenosyl-l-metionin (sam) salter.

Info

Publication number
NO161262C
NO161262C NO853075A NO853075A NO161262C NO 161262 C NO161262 C NO 161262C NO 853075 A NO853075 A NO 853075A NO 853075 A NO853075 A NO 853075A NO 161262 C NO161262 C NO 161262C
Authority
NO
Norway
Prior art keywords
salts
adenosyl
metionin
sam
preparation
Prior art date
Application number
NO853075A
Other languages
English (en)
Other versions
NO853075L (no
NO161262B (no
Inventor
Vincenzo Zappia
Mario De Rosa
Original Assignee
Gibipharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11158662&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO161262(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gibipharma Spa filed Critical Gibipharma Spa
Publication of NO853075L publication Critical patent/NO853075L/no
Publication of NO161262B publication Critical patent/NO161262B/no
Publication of NO161262C publication Critical patent/NO161262C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
NO853075A 1985-02-14 1985-08-02 Analogifremgangsm te for fremstilling av terapeutisk aktive s- adenosyl-l-metionin (sam) salter. NO161262C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19512/85A IT1200589B (it) 1985-02-14 1985-02-14 Derivati naturali attivita farmagologica

Publications (3)

Publication Number Publication Date
NO853075L NO853075L (no) 1986-08-15
NO161262B NO161262B (no) 1989-04-17
NO161262C true NO161262C (no) 1989-07-26

Family

ID=11158662

Family Applications (1)

Application Number Title Priority Date Filing Date
NO853075A NO161262C (no) 1985-02-14 1985-08-02 Analogifremgangsm te for fremstilling av terapeutisk aktive s- adenosyl-l-metionin (sam) salter.

Country Status (13)

Country Link
US (1) US4764603A (no)
EP (1) EP0191133B2 (no)
JP (1) JPS61189293A (no)
KR (1) KR870001902B1 (no)
CN (1) CN1012819B (no)
AT (1) ATE47715T1 (no)
CA (1) CA1264470A (no)
DE (2) DE191133T1 (no)
DK (1) DK160430C (no)
FI (1) FI81360C (no)
IL (1) IL76023A0 (no)
IT (1) IT1200589B (no)
NO (1) NO161262C (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03501970A (ja) * 1987-10-09 1991-05-09 ザッピア ヴィンセンツォ S‐アデノシル‐l‐メチオニン(sam)のアシル化タウリン誘導体との親油性塩
FR2623396B1 (fr) * 1987-11-25 1990-03-30 Sanofi Sa Utilisation de l'ademetionine contre le vieillissement de la peau
GB8900812D0 (en) * 1989-01-14 1989-03-08 Univ Manchester Pharmaceutical method and compositions
JPH02290896A (ja) * 1989-04-28 1990-11-30 Fuji Kagaku Kogyo Kk 新規なs―アデノシルメチオニン誘導体
US6399093B1 (en) 1999-05-19 2002-06-04 Advanced Medical Instruments Method and composition to treat musculoskeletal disorders
US6635615B1 (en) 1999-11-17 2003-10-21 Rolland F. Hebert Stable salts of S-adenosyl-l-methionine
US8642581B1 (en) 2000-02-11 2014-02-04 Brian D. Halevie-Goldman Compositions and methods for the production of S-adenosylmethionine within the body
US6805857B2 (en) * 2000-03-06 2004-10-19 Kumarpal A. Shah Method of modulating factor D, factor H and CD4 cell immune response with a polystyrene sulfonate, alginate, and saline infusion solution
EP1274444B1 (en) * 2000-03-16 2013-05-15 THE McLEAN HOSPITAL CORPORATION Cdp-choline and uridine for the treatment of alcohol abuse
US6759395B2 (en) * 2000-12-18 2004-07-06 Orchid Chemicals & Pharmaceuticals, Ltd. Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
FR2823211A1 (fr) * 2001-04-10 2002-10-11 Virbac Sa Composition a base d'un polyphosphate de s-adenosyl-l-methionine et utilisations d'un tel polyphosphate
EP1325740B1 (en) * 2001-12-12 2004-04-21 Chemistry & Health International B.V. Stable granulates containing S-Adenosylmethionine and process for the preparation thereof
US7387796B2 (en) * 2002-01-30 2008-06-17 Hebert Rolland F Stable compositions of S-adenosyl-l-methionine with dextran
US20040116351A1 (en) * 2002-12-06 2004-06-17 Fast Balance, Inc. Method for enhancing the natural reward system for exercise
UA88869C2 (ru) * 2002-12-20 2009-12-10 Зе Маклин Хоспитал Корпорейшн Соединения для нормализации цикла сон/бессонница
US20050272687A1 (en) * 2004-06-08 2005-12-08 Hebert Rolland F Stable S-adenosyl-l-methionine
EP1765364A4 (en) * 2004-06-10 2010-09-22 Mclean Hospital Corp PYRIMIDINES, SUCH AS Z: B: CYTIDINE, IN THE TREATMENT OF PATIENTS WITH BIPOLAR DISORDER
US7737128B2 (en) * 2004-06-10 2010-06-15 The Mclean Hospital Corporation Pyrimidines, such as uridine, in treatments for patients with bipolar disorder
US7947661B2 (en) * 2004-08-11 2011-05-24 The Mclean Hospital Corporation Compounds for the treatment of marihuana dependence, withdrawal, and usage
FR2884421B1 (fr) 2005-04-15 2007-08-10 Virbac Sa Nouveaux moyens de regulation des troubles du comportement chez les animaux de compagnie
US20090012036A1 (en) * 2005-05-24 2009-01-08 Hebert Rolland F Stable S-adenosyl-L-methionine
ITRM20050344A1 (it) * 2005-06-30 2007-01-01 Luca Maria De Sali o complessi di sostanze metil-donatrici con acido fitico o suoi derivati e relativo metodo di sintesi.
DE102005060690B4 (de) * 2005-12-15 2008-09-25 Capsulution Nanoscience Ag Salze von Clopidogrel mit Polyanionen und ihre Verwendung zur Herstellung pharmazeutischer Formulierungen
JP2008012464A (ja) * 2006-07-07 2008-01-24 Fujifilm Corp S−アデノシルメチオニンの抽出方法
JP4479932B2 (ja) * 2007-01-25 2010-06-09 三菱瓦斯化学株式会社 保存安定性に優れたs−アデノシル−l−メチオニン含有乾燥酵母の製造方法、その製造物及びその成型された組成物
US20100004191A1 (en) * 2008-07-01 2010-01-07 Rolland F Hebert Compositions of S-adenosyl-L-methionine.
US20100041621A1 (en) * 2008-08-15 2010-02-18 Perry Renshaw Methods and compositions for improving cognitive performance
EP2742943B1 (en) * 2011-08-12 2016-11-16 Mitsubishi Gas Chemical Company, Inc. Composition containing s-adenosyl-l-methionine with excellent storage stability
US20130064804A1 (en) * 2011-09-14 2013-03-14 Naidu Lp BIO-REPLENISHMENT (BioRep) FOR IMPROVING SLEEP ARCHITECTURE
WO2013080265A1 (ja) * 2011-12-02 2013-06-06 磐田化学工業株式会社 酸性メタリン酸ナトリウムによるs-アデノシルメチオニンの安定化
KR102186066B1 (ko) 2013-01-16 2020-12-04 허버트 샘-이 엘엘씨 S-아데노실-l-메티오닌의 안정한 인돌-3-프로피오네이트염
CN104211744A (zh) * 2013-05-30 2014-12-17 北京东方瑞德生物技术有限公司 一种s-腺苷蛋氨酸对甲苯磺酸硫酸盐的制备方法
RU2537556C1 (ru) * 2013-07-30 2015-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ получения соли адеметионина с хондроитинсульфокислотой
ITMI20131906A1 (it) * 2013-11-18 2015-05-19 Gnosis Spa Composizioni solide orali a lento rilascio
IT201700074957A1 (it) 2017-07-04 2019-01-04 Gnosis Spa Sale di (ss)-adenosil metionina con inositolo esafosfato e procedimento per ottenerlo

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE37913B1 (en) * 1972-08-02 1977-11-09 Bioresearch Sas Salt of s-adenosyl-l-methionine
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
IT1169900B (it) * 1983-10-26 1987-06-03 Tecofar Srl Sale di s-adenosil-l-metionina, composizione contenente tale sale preferibilmente per uso farmaceutico e procetimento di preparazione
IT1173992B (it) * 1984-05-16 1987-06-24 Bioresearch Spa Sali stabili della solfo-adenosil-l-metionina (same) particolarmente idonei per uso farmaceutico orale

Also Published As

Publication number Publication date
NO853075L (no) 1986-08-15
IL76023A0 (en) 1985-12-31
CA1264470A (en) 1990-01-16
CN1012819B (zh) 1991-06-12
FI852995A0 (fi) 1985-08-02
DE3574020D1 (en) 1989-12-07
US4764603A (en) 1988-08-16
DK160430B (da) 1991-03-11
FI81360C (fi) 1990-10-10
DK354785A (da) 1986-08-15
DK160430C (da) 1991-08-19
CN85107218A (zh) 1986-09-03
JPH0242839B2 (no) 1990-09-26
FI81360B (fi) 1990-06-29
DE191133T1 (de) 1987-02-05
FI852995L (fi) 1986-08-15
KR860006465A (ko) 1986-09-11
JPS61189293A (ja) 1986-08-22
DK354785D0 (da) 1985-08-05
IT8519512A0 (it) 1985-02-14
EP0191133B1 (en) 1989-11-02
EP0191133A3 (en) 1987-01-07
EP0191133B2 (en) 1994-08-17
ATE47715T1 (de) 1989-11-15
IT1200589B (it) 1989-01-27
EP0191133A2 (en) 1986-08-20
NO161262B (no) 1989-04-17
KR870001902B1 (ko) 1987-10-21

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