IL76023A0 - Stable salts of s-adenosyl-l-methionine(sam)with polyanions - Google Patents

Stable salts of s-adenosyl-l-methionine(sam)with polyanions

Info

Publication number
IL76023A0
IL76023A0 IL76023A IL7602385A IL76023A0 IL 76023 A0 IL76023 A0 IL 76023A0 IL 76023 A IL76023 A IL 76023A IL 7602385 A IL7602385 A IL 7602385A IL 76023 A0 IL76023 A0 IL 76023A0
Authority
IL
Israel
Prior art keywords
adenosyl
methionine
polyanions
sam
stable salts
Prior art date
Application number
IL76023A
Other languages
English (en)
Original Assignee
Gibipharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11158662&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL76023(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gibipharma Spa filed Critical Gibipharma Spa
Publication of IL76023A0 publication Critical patent/IL76023A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
IL76023A 1985-02-14 1985-08-06 Stable salts of s-adenosyl-l-methionine(sam)with polyanions IL76023A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19512/85A IT1200589B (it) 1985-02-14 1985-02-14 Derivati naturali attivita farmagologica

Publications (1)

Publication Number Publication Date
IL76023A0 true IL76023A0 (en) 1985-12-31

Family

ID=11158662

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76023A IL76023A0 (en) 1985-02-14 1985-08-06 Stable salts of s-adenosyl-l-methionine(sam)with polyanions

Country Status (13)

Country Link
US (1) US4764603A (xx)
EP (1) EP0191133B2 (xx)
JP (1) JPS61189293A (xx)
KR (1) KR870001902B1 (xx)
CN (1) CN1012819B (xx)
AT (1) ATE47715T1 (xx)
CA (1) CA1264470A (xx)
DE (2) DE191133T1 (xx)
DK (1) DK160430C (xx)
FI (1) FI81360C (xx)
IL (1) IL76023A0 (xx)
IT (1) IT1200589B (xx)
NO (1) NO161262C (xx)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03501970A (ja) * 1987-10-09 1991-05-09 ザッピア　ヴィンセンツォ Ｓ‐アデノシル‐ｌ‐メチオニン（ｓａｍ）のアシル化タウリン誘導体との親油性塩
FR2623396B1 (fr) * 1987-11-25 1990-03-30 Sanofi Sa Utilisation de l'ademetionine contre le vieillissement de la peau
GB8900812D0 (en) * 1989-01-14 1989-03-08 Univ Manchester Pharmaceutical method and compositions
JPH02290896A (ja) * 1989-04-28 1990-11-30 Fuji Kagaku Kogyo Kk 新規なｓ―アデノシルメチオニン誘導体
US6399093B1 (en) 1999-05-19 2002-06-04 Advanced Medical Instruments Method and composition to treat musculoskeletal disorders
US6635615B1 (en) 1999-11-17 2003-10-21 Rolland F. Hebert Stable salts of S-adenosyl-l-methionine
US8642581B1 (en) 2000-02-11 2014-02-04 Brian D. Halevie-Goldman Compositions and methods for the production of S-adenosylmethionine within the body
US6805857B2 (en) * 2000-03-06 2004-10-19 Kumarpal A. Shah Method of modulating factor D, factor H and CD4 cell immune response with a polystyrene sulfonate, alginate, and saline infusion solution
ES2425114T3 (es) * 2000-03-16 2013-10-11 The Mclean Hospital Corporation CDP-colina y uridina para el tratamiento del abuso del acohol
US6759395B2 (en) * 2000-12-18 2004-07-06 Orchid Chemicals & Pharmaceuticals, Ltd. Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
FR2823211A1 (fr) * 2001-04-10 2002-10-11 Virbac Sa Composition a base d'un polyphosphate de s-adenosyl-l-methionine et utilisations d'un tel polyphosphate
ATE264668T1 (de) * 2001-12-12 2004-05-15 Chemistry & Health Int Bv Lagerstabile granulate, die s-adenosylmethionin enthalten, und verfahren zu ihrer herstellung
US7387796B2 (en) * 2002-01-30 2008-06-17 Hebert Rolland F Stable compositions of S-adenosyl-l-methionine with dextran
US20040116351A1 (en) * 2002-12-06 2004-06-17 Fast Balance, Inc. Method for enhancing the natural reward system for exercise
CN100563660C (zh) * 2002-12-20 2009-12-02 麦克莱恩医院 用于正常化睡眠/觉醒周期的化合物
US20050272687A1 (en) * 2004-06-08 2005-12-08 Hebert Rolland F Stable S-adenosyl-l-methionine
EP1765364A4 (en) * 2004-06-10 2010-09-22 Mclean Hospital Corp PYRIMIDINES, SUCH AS Z: B: CYTIDINE, IN THE TREATMENT OF PATIENTS WITH BIPOLAR DISORDER
US7737128B2 (en) * 2004-06-10 2010-06-15 The Mclean Hospital Corporation Pyrimidines, such as uridine, in treatments for patients with bipolar disorder
US7947661B2 (en) * 2004-08-11 2011-05-24 The Mclean Hospital Corporation Compounds for the treatment of marihuana dependence, withdrawal, and usage
FR2884421B1 (fr) 2005-04-15 2007-08-10 Virbac Sa Nouveaux moyens de regulation des troubles du comportement chez les animaux de compagnie
US20090012036A1 (en) * 2005-05-24 2009-01-08 Hebert Rolland F Stable S-adenosyl-L-methionine
ITRM20050344A1 (it) * 2005-06-30 2007-01-01 Luca Maria De Sali o complessi di sostanze metil-donatrici con acido fitico o suoi derivati e relativo metodo di sintesi.
DE102005060690B4 (de) * 2005-12-15 2008-09-25 Capsulution Nanoscience Ag Salze von Clopidogrel mit Polyanionen und ihre Verwendung zur Herstellung pharmazeutischer Formulierungen
JP2008012464A (ja) * 2006-07-07 2008-01-24 Fujifilm Corp Ｓ−アデノシルメチオニンの抽出方法
AU2008208325B2 (en) * 2007-01-25 2013-02-07 Mitsubishi Gas Chemical Company, Inc. Method for production of dry yeast containing S-adenosyl-L-methionine and having excellent storage stability, product produced by the method, and molded composition of the dry yeast
US20100004191A1 (en) * 2008-07-01 2010-01-07 Rolland F Hebert Compositions of S-adenosyl-L-methionine.
US20100041621A1 (en) * 2008-08-15 2010-02-18 Perry Renshaw Methods and compositions for improving cognitive performance
KR101645619B1 (ko) * 2011-08-12 2016-08-05 미쯔비시 가스 케미칼 컴파니, 인코포레이티드 보존안정성이 우수한 s-아데노실-l-메티오닌 함유 조성물
US20130064804A1 (en) * 2011-09-14 2013-03-14 Naidu Lp BIO-REPLENISHMENT (BioRep) FOR IMPROVING SLEEP ARCHITECTURE
JP5808429B2 (ja) * 2011-12-02 2015-11-10 磐田化学工業株式会社 酸性メタリン酸ナトリウムによるｓ−アデノシルメチオニンの安定化
WO2014113609A1 (en) 2013-01-16 2014-07-24 Hebert Sam-E Llc Stable indole-3-propionate salts of s-adenosyl-l-methionine
CN104211744A (zh) * 2013-05-30 2014-12-17 北京东方瑞德生物技术有限公司 一种s-腺苷蛋氨酸对甲苯磺酸硫酸盐的制备方法
RU2537556C1 (ru) * 2013-07-30 2015-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ получения соли адеметионина с хондроитинсульфокислотой
ITMI20131906A1 (it) * 2013-11-18 2015-05-19 Gnosis Spa Composizioni solide orali a lento rilascio
IT201700074957A1 (it) 2017-07-04 2019-01-04 Gnosis Spa Sale di (ss)-adenosil metionina con inositolo esafosfato e procedimento per ottenerlo

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE37913B1 (en) * 1972-08-02 1977-11-09 Bioresearch Sas Salt of s-adenosyl-l-methionine
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
IT1169900B (it) * 1983-10-26 1987-06-03 Tecofar Srl Sale di s-adenosil-l-metionina, composizione contenente tale sale preferibilmente per uso farmaceutico e procetimento di preparazione
IT1173992B (it) * 1984-05-16 1987-06-24 Bioresearch Spa Sali stabili della solfo-adenosil-l-metionina (same) particolarmente idonei per uso farmaceutico orale

Also Published As

Publication number Publication date
CA1264470A (en) 1990-01-16
DK354785D0 (da) 1985-08-05
NO161262C (no) 1989-07-26
EP0191133B1 (en) 1989-11-02
CN1012819B (zh) 1991-06-12
DE191133T1 (de) 1987-02-05
DK160430B (da) 1991-03-11
KR870001902B1 (ko) 1987-10-21
EP0191133A3 (en) 1987-01-07
KR860006465A (ko) 1986-09-11
DK354785A (da) 1986-08-15
US4764603A (en) 1988-08-16
JPH0242839B2 (xx) 1990-09-26
EP0191133B2 (en) 1994-08-17
IT1200589B (it) 1989-01-27
DE3574020D1 (en) 1989-12-07
FI852995L (fi) 1986-08-15
ATE47715T1 (de) 1989-11-15
NO853075L (no) 1986-08-15
NO161262B (no) 1989-04-17
CN85107218A (zh) 1986-09-03
DK160430C (da) 1991-08-19
FI81360B (fi) 1990-06-29
EP0191133A2 (en) 1986-08-20
FI81360C (fi) 1990-10-10
JPS61189293A (ja) 1986-08-22
FI852995A0 (fi) 1985-08-02
IT8519512A0 (it) 1985-02-14

Similar Documents

Publication Publication Date Title
DE3574020D1 (en) Stable salts of sam with polyanions
SE7611379L (sv) Antihypertensiva medel
CA2113995A1 (en) Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
IL81002A (en) 3,4-diphenyl-pyrazoline-1-carboxamide derivatives,processes for the preparation thereof and insecticidal and acaricidal compositions containing the same
GR3025742T3 (en) New pyrazine derivatives, their preparation and their use.
MY102929A (en) Aqueous pharmaceutical formulations of piroxicam monohydrate
TR200100896T2 (tr) İkameli propanol türevleri, imalat yöntemleri, bileşimleri içeren ilaçlar, kullanımları
ATE60604T1 (de) 1h-indol-3-yl enthaltende 1,3-dimethyl-1-h-purine-2,6-dione.
DK0413793T3 (da) Koncentrerede vandige emulsioner, en fremgangsmåde til deres fremstilling og deres anvendelse på pesticidområdet
KAwAI et al. The impairing effect of chaetochromin A and related mycotoxins on mitochondrial respiration
IT1197516B (it) Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
JPS5726587A (en) Stabilization of ascorbic acid oxidase
AU578125B2 (en) Pyrazine diazohydroxide compounds
JPS5344591A (en) Preparation of adenine derivatives
JPS559046A (en) Composition for skin application
KAwAI et al. Proc. Jpn. Assoc. Mycotoxicol. No. 33, 1991 31
Froltsova et al. Study of specific toxicity of Soviet antihelminthic drug medamine.
JPS5428808A (en) Composition containing s-adenoyl-l-methionine and its preparation
JPS57144217A (en) Antitumor agent

Legal Events

Date Code Title Description
RH Patent void