JPS57144217A - Antitumor agent - Google Patents
Antitumor agentInfo
- Publication number
- JPS57144217A JPS57144217A JP3081381A JP3081381A JPS57144217A JP S57144217 A JPS57144217 A JP S57144217A JP 3081381 A JP3081381 A JP 3081381A JP 3081381 A JP3081381 A JP 3081381A JP S57144217 A JPS57144217 A JP S57144217A
- Authority
- JP
- Japan
- Prior art keywords
- cytosine
- fluorocytosine
- antitumor agent
- antitumor
- methylcytosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: An antitumor agent having extremely raised antitumor action, obtained by combining an antitumor agent consisting of 5-fluorocytosine and cytosine deaminase with cytosine and/or 5-methylcytosine.
CONSTITUTION: An antitumor agent consisting of 5-fluorocytosine and cytosine deaminase is blended with 0.5W20pts.wt., preferably 4W6pts.wt. based on 1pts.wt. 5-fluorocytosine of cytosine and/or 5-methyl cytosine. These compounds have no antitumor action at all individually, but combined and used, they exhibit extremely high antitumor action. 5-Fluorocytosine, cytosine and/or 5-methylcytosine are separately or simultaneously medicated to the whole body, and cytosine deaminase is locally medicated to the tumor tissue. By actions of various kinds of enzymes 5-fluorocytosine is converted into 5-fluorouracil.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3081381A JPS57144217A (en) | 1981-03-04 | 1981-03-04 | Antitumor agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3081381A JPS57144217A (en) | 1981-03-04 | 1981-03-04 | Antitumor agent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57144217A true JPS57144217A (en) | 1982-09-06 |
Family
ID=12314124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3081381A Pending JPS57144217A (en) | 1981-03-04 | 1981-03-04 | Antitumor agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57144217A (en) |
-
1981
- 1981-03-04 JP JP3081381A patent/JPS57144217A/en active Pending
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