JPS5524150A - Anti-malignant-tumor agent - Google Patents
Anti-malignant-tumor agentInfo
- Publication number
- JPS5524150A JPS5524150A JP9770378A JP9770378A JPS5524150A JP S5524150 A JPS5524150 A JP S5524150A JP 9770378 A JP9770378 A JP 9770378A JP 9770378 A JP9770378 A JP 9770378A JP S5524150 A JPS5524150 A JP S5524150A
- Authority
- JP
- Japan
- Prior art keywords
- arabinofuranosylcytosine
- cytidine
- tumor agent
- malignant
- mole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To provide an anti-malignant tumor agent which keeps high concentration in the living body and has improved effectivity, by compounding 1-β-D-arabinofuranosylcytosine and a compound such as cytidine.
CONSTITUTION: A composition containing 1 mole of 1-β-D-arabinofuranosylcytosine and ≥0.5 mole, pref. 1W20 moles of cytidine or uridine. The arabinofuranosylcytosine which is decomposed and inactivated at a half life time in blood of about 15W20 minutes by intravenous injection, is stabilized by addition of cytidine, etc., and its anti-tumor activity is improved.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9770378A JPS5524150A (en) | 1978-08-09 | 1978-08-09 | Anti-malignant-tumor agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9770378A JPS5524150A (en) | 1978-08-09 | 1978-08-09 | Anti-malignant-tumor agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5524150A true JPS5524150A (en) | 1980-02-21 |
JPS6231690B2 JPS6231690B2 (en) | 1987-07-09 |
Family
ID=14199276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9770378A Granted JPS5524150A (en) | 1978-08-09 | 1978-08-09 | Anti-malignant-tumor agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5524150A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5470838A (en) * | 1987-10-28 | 1995-11-28 | Pro-Neuron, Inc. | Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine |
US5583117A (en) * | 1987-10-28 | 1996-12-10 | Pro-Neuron, Inc. | Acylated uridine and cytidine for elevating tissue uridine and cytidine |
-
1978
- 1978-08-09 JP JP9770378A patent/JPS5524150A/en active Granted
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5470838A (en) * | 1987-10-28 | 1995-11-28 | Pro-Neuron, Inc. | Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine |
US5583117A (en) * | 1987-10-28 | 1996-12-10 | Pro-Neuron, Inc. | Acylated uridine and cytidine for elevating tissue uridine and cytidine |
US6258795B1 (en) | 1987-10-28 | 2001-07-10 | Pro-Neuron, Inc. | Acylated uridine and cytidine and uses thereof |
US6274563B1 (en) | 1987-10-28 | 2001-08-14 | Pro-Neuron, Inc. | Acylated uridine and cytidine and uses thereof |
US6316426B1 (en) | 1987-10-28 | 2001-11-13 | Pro-Neuron, Inc. | Acylated uridine and cytidine and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
JPS6231690B2 (en) | 1987-07-09 |
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