NO158100C - Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazo (4,5-c)pyridinderivater. - Google Patents
Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazo (4,5-c)pyridinderivater.Info
- Publication number
- NO158100C NO158100C NO823732A NO823732A NO158100C NO 158100 C NO158100 C NO 158100C NO 823732 A NO823732 A NO 823732A NO 823732 A NO823732 A NO 823732A NO 158100 C NO158100 C NO 158100C
- Authority
- NO
- Norway
- Prior art keywords
- pyridine
- ingredients
- preparation
- therapeutic active
- analogue procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8133942 | 1981-11-10 | ||
GB8133930 | 1981-11-10 | ||
GB8213846 | 1982-05-12 |
Publications (3)
Publication Number | Publication Date |
---|---|
NO823732L NO823732L (no) | 1983-05-11 |
NO158100B NO158100B (no) | 1988-04-05 |
NO158100C true NO158100C (no) | 1988-07-13 |
Family
ID=27261362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO823732A NO158100C (no) | 1981-11-10 | 1982-11-09 | Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazo (4,5-c)pyridinderivater. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4603139A (fi) |
EP (1) | EP0079083B1 (fi) |
KR (1) | KR890000022B1 (fi) |
AR (1) | AR241247A1 (fi) |
AU (1) | AU9030682A (fi) |
DD (1) | DD205904A5 (fi) |
DK (1) | DK161325C (fi) |
ES (2) | ES8401486A1 (fi) |
FI (1) | FI79312C (fi) |
GB (1) | GB2113675B (fi) |
GR (1) | GR76746B (fi) |
IE (1) | IE56478B1 (fi) |
IL (1) | IL67206A0 (fi) |
MC (1) | MC1491A1 (fi) |
NO (1) | NO158100C (fi) |
PH (1) | PH22764A (fi) |
PT (1) | PT75820B (fi) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3273461D1 (en) * | 1981-08-19 | 1986-10-30 | Merck Patent Gmbh | 2-arylimidazopyridines |
IL68495A0 (en) * | 1982-05-03 | 1983-07-31 | Lilly Co Eli | 2-phenylimidazo(4,5-c)pyridines |
US4758574A (en) * | 1982-05-03 | 1988-07-19 | Eli Lilly And Company | 2-phenylimidazio (4,5-c) pyridines |
US4904785A (en) * | 1982-05-03 | 1990-02-27 | Eli Lilly And Company | 2-phenylimidazo[4,5-c]pyridines |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
DE3324115A1 (de) * | 1983-07-05 | 1985-01-17 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
US4515796A (en) * | 1983-09-08 | 1985-05-07 | Eli Lilly And Company | Certain naphthalenyl imidazo compounds and their pharmaceutical use |
US4533734A (en) * | 1983-11-10 | 1985-08-06 | Eli Lilly And Company | Inotropic agents |
DE3346602A1 (de) * | 1983-12-23 | 1985-07-11 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazo(4,5-c)pyridin-one, deren herstellung und diese verbindungen enthaltende arzneimittel |
DE3347290A1 (de) * | 1983-12-28 | 1985-07-11 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
ZA851236B (en) * | 1984-02-24 | 1986-09-24 | Lilly Co Eli | 2-arylimidazo 4,5-cpyridines |
US4578387A (en) * | 1984-03-05 | 1986-03-25 | Eli Lilly And Company | Inotropic agents |
DE3445299A1 (de) * | 1984-12-12 | 1986-06-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
CA1295330C (en) * | 1985-03-29 | 1992-02-04 | James M. Greene | Synthesis of inotropic imidazo(4,5-c) pyridine |
DE3522230A1 (de) * | 1985-06-21 | 1987-01-02 | Thomae Gmbh Dr K | Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
US4740599A (en) * | 1986-10-03 | 1988-04-26 | Eli Lilly And Company | Synthesis of alkylsulfinyl substituted 2-phenylimidazo(4,5-c)pyridines |
ZA889365B (en) * | 1987-12-22 | 1990-08-29 | Lilly Co Eli | Hydrates of andinotropic agent |
GB8822170D0 (en) * | 1988-09-21 | 1988-10-26 | Pfizer Ltd | Therapeutic agents |
EP0533695B1 (en) * | 1990-05-09 | 1994-10-05 | Pfizer Inc. | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY |
DE4324580A1 (de) * | 1993-07-22 | 1995-01-26 | Thomae Gmbh Dr K | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
US6020340A (en) * | 1996-05-15 | 2000-02-01 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Imidazopyridines |
WO1998021209A1 (de) * | 1996-11-11 | 1998-05-22 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue imidazo- und oxazolopyridine |
MXPA02010763A (es) | 2000-06-14 | 2003-03-10 | Warner Lambert Co | Heterociclicos biciclos-6,5 fusionados. |
AU2004215664A1 (en) * | 2003-02-25 | 2004-09-10 | Altana Pharma Ag | Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors |
KR20060087386A (ko) * | 2005-01-28 | 2006-08-02 | 주식회사 대웅제약 | 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물 |
WO2007034277A1 (en) * | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Aryl substituted imidazo [4,5-c] pyridine compounds as c3a receptor antagonists |
KR101686685B1 (ko) | 2008-10-31 | 2016-12-14 | 제넨테크, 인크. | 피라졸로피리미딘 jak 억제제 화합물 및 방법 |
UA110324C2 (en) | 2009-07-02 | 2015-12-25 | Genentech Inc | Jak inhibitory compounds based on pyrazolo pyrimidine |
DK2464232T3 (en) * | 2009-08-10 | 2016-01-04 | Samumed Llc | INDAZOLE INHIBITORS OF THE WNT SIGNAL ROAD AND THERAPEUTIC APPLICATIONS THEREOF |
ES2550820T3 (es) | 2009-12-21 | 2015-11-12 | Samumed, Llc | 1H-pirazol[3,4-beta]piridinas y usos terapéuticos de las mismas |
US20130096104A1 (en) * | 2010-03-17 | 2013-04-18 | Genentech, Inc. | Imidazopyridine compounds, compositions and methods of use |
CN103209695A (zh) | 2010-09-15 | 2013-07-17 | 弗·哈夫曼-拉罗切有限公司 | 氮杂苯并噻唑化合物、组合物及应用方法 |
BR112013011520A2 (pt) | 2010-11-19 | 2019-09-24 | Hoffmann La Roche | pirazolo piridinas e pirazolo piridinas e seu uso como inibidores de tyk2 |
DK2755483T3 (en) | 2011-09-14 | 2019-03-11 | Samumed Llc | INDAZOL-3-CARBOXAMIDES AND ITS USE AS WNT / B-CATENIN SIGNAL INHIBITORS |
PH12017500997A1 (en) | 2012-04-04 | 2018-02-19 | Samumed Llc | Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof |
BR112014024284B1 (pt) | 2012-05-04 | 2021-08-31 | Samumed, Llc | Compostos de 1h-pirazolo[3,4-b]piridinas, composição farmacêutica compreendendo ditos compostos e usos terapêuticos destes |
MX370487B (es) | 2013-01-08 | 2019-12-16 | Samumed Llc | Inhibidores de 3-(benzo-imidazol-2-il)-indazol de la senda de señalización de wnt y usos terapéuticos de los mismos. |
EP2818472A1 (en) * | 2013-06-27 | 2014-12-31 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Imidazo[4,5-c]pyridine and pyrrolo[3,2-c]pyridine compounds as G-protein-coupled receptor kinase 5 (GRK5) modulators |
CN105431433B (zh) * | 2013-07-02 | 2018-04-06 | 先正达参股股份有限公司 | 有杀有害生物活性的具有含硫取代基的二环或三环杂环 |
RU2016103149A (ru) * | 2013-07-02 | 2017-08-07 | Зингента Партисипейшнс Аг | Пестицидно-активные би-или трициклические гетероциклы с серосодержащими заместителями |
US11229208B2 (en) | 2013-07-02 | 2022-01-25 | Syngenta Participations Ag | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents |
PE20171645A1 (es) * | 2014-02-17 | 2017-11-13 | Bayer Cropscience Ag | Derivados de heterociclos biciclicos condensados sustituidos con 2-(het)arilo como agentes para combatir parasitos |
WO2015177326A1 (en) | 2014-05-23 | 2015-11-26 | F. Hoffmann-La Roche Ag | 5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds which are jak inhibitors |
ES2701859T3 (es) * | 2014-08-21 | 2019-02-26 | Syngenta Participations Ag | Derivados heterocíclicos activos como plaguicida con sustituyentes que contienen azufre |
WO2016040181A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040180A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040182A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof |
WO2016040184A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040190A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
WO2016040185A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof |
WO2016040188A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040193A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
WO2016058928A1 (en) * | 2014-10-14 | 2016-04-21 | Syngenta Participations Ag | Pesticidally active heterocyclic derivatives with sulphur containing substituents |
HUE050562T2 (hu) * | 2014-12-17 | 2020-12-28 | Syngenta Participations Ag | Pezticid hatású heterociklus-származékok kéntartalmú szubsztituensekkel |
US10385048B2 (en) * | 2014-12-31 | 2019-08-20 | Syngenta Participation Ag | Pesticidally active polycyclic derivatives with sulfur containing substituents |
UY36547A (es) * | 2015-02-05 | 2016-06-01 | Bayer Cropscience Ag | Derivados heterocíclicos condensados bicíclicos sustituidos por 2-(het)arilo como pesticidas |
WO2017024004A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
US10604512B2 (en) | 2015-08-03 | 2020-03-31 | Samumed, Llc | 3-(1H-indol-2-yl)-1H-indazoles and therapeutic uses thereof |
WO2017023993A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-indol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
WO2017023984A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof |
US10285983B2 (en) | 2015-08-03 | 2019-05-14 | Samumed, Llc | 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof |
WO2017023972A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
WO2017024025A1 (en) | 2015-08-03 | 2017-02-09 | Sunil Kumar Kc | 3-(1h-pyrrolo[2,3-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
US10383861B2 (en) | 2015-08-03 | 2019-08-20 | Sammumed, LLC | 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof |
US10226448B2 (en) | 2015-08-03 | 2019-03-12 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridines and therapeutic uses thereof |
WO2017023988A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
WO2017024015A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
WO2017024010A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof |
WO2017024026A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc | 3-(1h-indol-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof |
WO2017024021A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof |
WO2017023980A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof |
US10392383B2 (en) | 2015-08-03 | 2019-08-27 | Samumed, Llc | 3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
US10231956B2 (en) | 2015-08-03 | 2019-03-19 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
JP6982747B2 (ja) | 2015-11-06 | 2021-12-17 | バイオスプライス セラピューティクス インコーポレイテッド | 変形性関節症の処置 |
CN109476660B (zh) | 2016-06-01 | 2023-04-04 | 拜斯丽治疗有限公司 | N-(5-(3-(7-(3-氟苯基)-3h-咪唑并[4,5-c]吡啶-2-基)-1h-吲唑-5-基)吡啶-3-基)-3-甲基丁酰胺的制备方法 |
CA3041291A1 (en) | 2016-10-21 | 2018-04-26 | Samumed, Llc | Methods of using indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors |
MA46696A (fr) | 2016-11-07 | 2019-09-11 | Samumed Llc | Formulations injectables à dose unique prêtes à l'emploi |
EP3630766A1 (en) | 2017-05-22 | 2020-04-08 | H. Hoffnabb-La Roche Ag | Therapeutic compounds and compositions, and methods of use thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA820316A (en) * | 1969-08-12 | Fisons Pest Control Limited | Substituted heterocyclic compounds | |
US3985891A (en) * | 1973-02-03 | 1976-10-12 | Boehringer Ingelheim Gmbh | 2-Phenyl-imidazo (4,5-b)pyridines and salts thereof |
FI58126C (fi) * | 1973-02-03 | 1980-12-10 | Thomae Gmbh Dr K | Foerfarande foer framstaellning av kardiotona och blodtryckssaenkande 2-fenyl-1h-imidatso(4,5-b)pyridiner |
US3891660A (en) * | 1974-02-07 | 1975-06-24 | Squibb & Sons Inc | Derivatives of 1H-imidazo{8 4,5-c{9 pyridine-7-carboxylic acids and esters |
SU566842A1 (ru) * | 1976-01-06 | 1977-07-30 | Донецкое Отделение Физико-Органической Химии Института Физической Химии Им.Л.В.Писаржевского Ан Украинской Сср | Способ получени замещенных имидазопиридинов |
US4281005A (en) * | 1979-03-05 | 1981-07-28 | Merck & Co., Inc. | Novel 2-pyridylimidazole compounds |
DE2927987A1 (de) * | 1979-07-11 | 1981-02-05 | Thomae Gmbh Dr K | Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel |
DE3037464A1 (de) * | 1980-10-03 | 1982-05-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | 6-hydroxy-2-phenyl-imidazo 4,5-b zu pyridine, ihre herstellung und diese sie enthaltende arzneimittel |
DE3273461D1 (en) * | 1981-08-19 | 1986-10-30 | Merck Patent Gmbh | 2-arylimidazopyridines |
IL68495A0 (en) * | 1982-05-03 | 1983-07-31 | Lilly Co Eli | 2-phenylimidazo(4,5-c)pyridines |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
-
1982
- 1982-11-08 ES ES517193A patent/ES8401486A1/es not_active Expired
- 1982-11-09 KR KR8205055A patent/KR890000022B1/ko active
- 1982-11-09 AU AU90306/82A patent/AU9030682A/en not_active Abandoned
- 1982-11-09 MC MC821611A patent/MC1491A1/xx unknown
- 1982-11-09 IL IL67206A patent/IL67206A0/xx unknown
- 1982-11-09 AR AR82291240A patent/AR241247A1/es active
- 1982-11-09 EP EP82110328A patent/EP0079083B1/en not_active Expired - Lifetime
- 1982-11-09 IE IE2667/82A patent/IE56478B1/en not_active IP Right Cessation
- 1982-11-09 DD DD82244689A patent/DD205904A5/de not_active IP Right Cessation
- 1982-11-09 DK DK499582A patent/DK161325C/da not_active IP Right Cessation
- 1982-11-09 PH PH28109A patent/PH22764A/en unknown
- 1982-11-09 PT PT75820A patent/PT75820B/pt unknown
- 1982-11-09 GB GB08231984A patent/GB2113675B/en not_active Expired
- 1982-11-09 NO NO823732A patent/NO158100C/no unknown
- 1982-11-09 GR GR69767A patent/GR76746B/el unknown
- 1982-11-09 FI FI823846A patent/FI79312C/fi not_active IP Right Cessation
-
1983
- 1983-06-08 ES ES523083A patent/ES523083A0/es active Granted
-
1985
- 1985-01-11 US US06/690,815 patent/US4603139A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PT75820B (en) | 1986-06-11 |
NO158100B (no) | 1988-04-05 |
IE822667L (en) | 1983-05-10 |
EP0079083A1 (en) | 1983-05-18 |
ES517193A0 (es) | 1983-12-01 |
ES8503351A1 (es) | 1985-02-16 |
AR241247A1 (es) | 1992-03-31 |
KR840002398A (ko) | 1984-07-02 |
GB2113675B (en) | 1985-10-30 |
NO823732L (no) | 1983-05-11 |
AU9030682A (en) | 1983-05-19 |
DK161325B (da) | 1991-06-24 |
ES8401486A1 (es) | 1983-12-01 |
KR890000022B1 (ko) | 1989-03-06 |
PT75820A (en) | 1982-12-01 |
FI79312B (fi) | 1989-08-31 |
DK161325C (da) | 1991-12-02 |
FI79312C (fi) | 1989-12-11 |
MC1491A1 (fr) | 1983-09-12 |
DK499582A (da) | 1983-05-11 |
GR76746B (fi) | 1984-08-30 |
EP0079083B1 (en) | 1991-02-27 |
FI823846L (fi) | 1983-05-11 |
IE56478B1 (en) | 1991-08-14 |
PH22764A (en) | 1988-12-12 |
FI823846A0 (fi) | 1982-11-09 |
DD205904A5 (de) | 1984-01-11 |
ES523083A0 (es) | 1985-02-16 |
GB2113675A (en) | 1983-08-10 |
US4603139A (en) | 1986-07-29 |
IL67206A0 (en) | 1983-03-31 |
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NO158100C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazo (4,5-c)pyridinderivater. | |
NO157620C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazo -diazepiner. | |
NO157781C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye imidazo(1,2-a)pyridiner. | |
NO166327C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive piperidinderivater. | |
NO159724C (no) | Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazo(1,2-a)-pyraziner. | |
NO156785C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive cyklobutan-derivater. | |
NO156373C (no) | Analogifremgangsmte for fremstilling av terapeutisk aktive furo-(3,4-c)-pyridinderivater. | |
NO162022C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive cefemderivater. | |
NO158419C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2-diaminocyklobuten-3,4-dioner. | |
NO154905C (no) | Fremgangsmaate for fremstilling av preparater for behandling av melanomer. | |
NO162189C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazopyridiner. | |
NO157819C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazo (1,2-a)-pyridin-2-yl-karbostyrilforbindelser. | |
NO821085L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive omega-cyan-1, omega-difenyl-azaalkanderivater | |
NO161497C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 9a-aza-9a-homoerytromycin-derivater. | |
NO883750L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive piperidinderivater. | |
NO158460C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive forbindelser. | |
NO161319C (no) | Analogifremgangsmaate til fremstilling av terapeutisk virksomme imidazo-(1,5-a)pyridin-derivater. | |
NO164295C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive fluorerte benzyltriazolforbindelser. | |
NO861584L (no) | Fremgangsmaate til fremstilling av terapeutisk aktive cyklopentyletere. | |
NO153137C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte pyrido(1,2-a)pyrimidiner. | |
NO159276C (no) | Analogifremgangsmaate til fremstilling av terapeutisk virksomme imidazo(1,5-a)pyridiner. | |
NO159090C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridoindol-derivater. | |
NO163570C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive acylaminomitosaner. | |
NO160442C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive pyrazolo (1,5-a)pyridinderivater. | |
NO162188C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinoliner. |