NO149428C - Fremgangsmaate for fremstilling av fysiologisk aktive prostaglandinderivater. - Google Patents

Fremgangsmaate for fremstilling av fysiologisk aktive prostaglandinderivater.

Info

Publication number
NO149428C
NO149428C NO771134A NO771134A NO149428C NO 149428 C NO149428 C NO 149428C NO 771134 A NO771134 A NO 771134A NO 771134 A NO771134 A NO 771134A NO 149428 C NO149428 C NO 149428C
Authority
NO
Norway
Prior art keywords
ingrediates
prostagland
procedure
preparation
physiologically active
Prior art date
Application number
NO771134A
Other languages
English (en)
Norwegian (no)
Other versions
NO149428B (no
NO771134L (no
Inventor
Souli Nanthavong
Charles Pigerol
Pierre Eymard
Jacques Simiand
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO771134L publication Critical patent/NO771134L/no
Publication of NO149428B publication Critical patent/NO149428B/no
Publication of NO149428C publication Critical patent/NO149428C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
NO771134A 1976-03-31 1977-03-30 Fremgangsmaate for fremstilling av fysiologisk aktive prostaglandinderivater. NO149428C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL49325A IL49325A (en) 1976-03-31 1976-03-31 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
NO771134L NO771134L (no) 1977-10-03
NO149428B NO149428B (no) 1984-01-09
NO149428C true NO149428C (no) 1984-04-18

Family

ID=11048789

Family Applications (1)

Application Number Title Priority Date Filing Date
NO771134A NO149428C (no) 1976-03-31 1977-03-30 Fremgangsmaate for fremstilling av fysiologisk aktive prostaglandinderivater.

Country Status (18)

Country Link
US (1) US4115401A (en:Method)
JP (1) JPS52142060A (en:Method)
BE (1) BE852941A (en:Method)
CA (1) CA1074804A (en:Method)
CH (2) CH624101A5 (en:Method)
DD (1) DD130352A5 (en:Method)
DE (1) DE2714129A1 (en:Method)
ES (1) ES457385A1 (en:Method)
FR (1) FR2346332A1 (en:Method)
GB (1) GB1574246A (en:Method)
HU (1) HU178040B (en:Method)
IL (1) IL49325A (en:Method)
IT (1) IT1075373B (en:Method)
NL (1) NL7703503A (en:Method)
NO (1) NO149428C (en:Method)
PL (3) PL107544B1 (en:Method)
SE (1) SE417603B (en:Method)
SU (3) SU676162A3 (en:Method)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK290079A (da) * 1978-07-11 1980-01-12 Glaxo Group Ltd Fremgangsmaade til fremstilling af prostanoidforbindelser
US4320136A (en) * 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
US4530933A (en) * 1982-12-27 1985-07-23 E. I. Du Pont De Nemours And Company 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents
US4456613A (en) * 1982-12-27 1984-06-26 E. I. Du Pont De Nemours And Company 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof
CN1413190A (zh) 1999-12-22 2003-04-23 辉瑞产品公司 治疗骨质疏松的ep4受体选择性激动剂
PT1339678E (pt) * 2000-11-27 2007-11-30 Pfizer Prod Inc Agonistas selectivos do receptor ep4 no tratamento de osteoporose
JP4211605B2 (ja) * 2001-07-16 2009-01-21 小野薬品工業株式会社 プロスタノイドアゴニストとしての２ピロリドン誘導体
RU2288913C2 (ru) 2001-07-16 2006-12-10 Ф.Хоффманн-Ля Рош Аг Аналоги простагландинов, способ их получения и фармацевтическая композиция, обладающая селективной агонистической активностью в отношении рецептора ep4
IL159996A0 (en) 2001-07-23 2004-06-20 Ono Pharmaceutical Co Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient
US7402605B2 (en) 2002-03-05 2008-07-22 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
JP2005526080A (ja) * 2002-03-18 2005-09-02 ファイザー・プロダクツ・インク 肝不全、動脈管閉鎖、緑内障又は高眼圧の治療のための選択的ｅｐ４受容体アゴニストの使用
JP2006515015A (ja) * 2003-01-10 2006-05-18 エフ．ホフマン−ラ　ロシュ　アーゲー プロスタグランジンアゴニストとしての２−ピペリドン誘導体
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US20080058375A1 (en) * 2004-01-08 2008-03-06 Elworthy Todd R 2-Piperidone derivatives as prostaglandin antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones

Also Published As

Publication number Publication date
JPS52142060A (en) 1977-11-26
BE852941A (fr) 1977-09-28
IT1075373B (it) 1985-04-22
US4115401A (en) 1978-09-19
SE417603B (sv) 1981-03-30
SU715019A3 (ru) 1980-02-05
GB1574246A (en) 1980-09-03
CH628032A5 (fr) 1982-02-15
SU676162A3 (ru) 1979-07-25
SU837321A3 (ru) 1981-06-07
IL49325A (en) 1979-11-30
IL49325A0 (en) 1976-05-31
PL107643B1 (pl) 1980-02-29
PL108289B1 (pl) 1980-03-31
PL197005A1 (pl) 1978-10-09
DD130352A5 (de) 1978-03-22
PL107544B1 (pl) 1980-02-29
NO149428B (no) 1984-01-09
SE7703698L (sv) 1977-10-01
HU178040B (en) 1982-02-28
CA1074804A (en) 1980-04-01
NL7703503A (nl) 1977-10-04
FR2346332A1 (fr) 1977-10-28
CH624101A5 (en:Method) 1981-07-15
DE2714129A1 (de) 1977-10-13
FR2346332B1 (en:Method) 1980-05-09
NO771134L (no) 1977-10-03
ES457385A1 (es) 1978-02-01

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