HU178040B - Process for preparing 8-aza-prostaglandin derivatives - Google Patents
Process for preparing 8-aza-prostaglandin derivativesInfo
- Publication number
- HU178040B HU178040B HU77LA913A HULA000913A HU178040B HU 178040 B HU178040 B HU 178040B HU 77LA913 A HU77LA913 A HU 77LA913A HU LA000913 A HULA000913 A HU LA000913A HU 178040 B HU178040 B HU 178040B
- Authority
- HU
- Hungary
- Prior art keywords
- aza
- preparing
- prostaglandin derivatives
- prostaglandin
- derivatives
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/126—Acids containing more than four carbon atoms
- C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL49325A IL49325A (en) | 1976-03-31 | 1976-03-31 | 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU178040B true HU178040B (en) | 1982-02-28 |
Family
ID=11048789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU77LA913A HU178040B (en) | 1976-03-31 | 1977-03-30 | Process for preparing 8-aza-prostaglandin derivatives |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4115401A (en:Method) |
| JP (1) | JPS52142060A (en:Method) |
| BE (1) | BE852941A (en:Method) |
| CA (1) | CA1074804A (en:Method) |
| CH (2) | CH624101A5 (en:Method) |
| DD (1) | DD130352A5 (en:Method) |
| DE (1) | DE2714129A1 (en:Method) |
| ES (1) | ES457385A1 (en:Method) |
| FR (1) | FR2346332A1 (en:Method) |
| GB (1) | GB1574246A (en:Method) |
| HU (1) | HU178040B (en:Method) |
| IL (1) | IL49325A (en:Method) |
| IT (1) | IT1075373B (en:Method) |
| NL (1) | NL7703503A (en:Method) |
| NO (1) | NO149428C (en:Method) |
| PL (3) | PL107544B1 (en:Method) |
| SE (1) | SE417603B (en:Method) |
| SU (3) | SU676162A3 (en:Method) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK290079A (da) * | 1978-07-11 | 1980-01-12 | Glaxo Group Ltd | Fremgangsmaade til fremstilling af prostanoidforbindelser |
| US4320136A (en) * | 1980-08-11 | 1982-03-16 | E. I. Du Pont De Nemours And Company | 8-Aza-16,16-difluoroprostanoids |
| US4530933A (en) * | 1982-12-27 | 1985-07-23 | E. I. Du Pont De Nemours And Company | 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents |
| US4456613A (en) * | 1982-12-27 | 1984-06-26 | E. I. Du Pont De Nemours And Company | 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof |
| CN1413190A (zh) | 1999-12-22 | 2003-04-23 | 辉瑞产品公司 | 治疗骨质疏松的ep4受体选择性激动剂 |
| PT1339678E (pt) * | 2000-11-27 | 2007-11-30 | Pfizer Prod Inc | Agonistas selectivos do receptor ep4 no tratamento de osteoporose |
| JP4211605B2 (ja) * | 2001-07-16 | 2009-01-21 | 小野薬品工業株式会社 | プロスタノイドアゴニストとしての２ピロリドン誘導体 |
| RU2288913C2 (ru) | 2001-07-16 | 2006-12-10 | Ф.Хоффманн-Ля Рош Аг | Аналоги простагландинов, способ их получения и фармацевтическая композиция, обладающая селективной агонистической активностью в отношении рецептора ep4 |
| IL159996A0 (en) | 2001-07-23 | 2004-06-20 | Ono Pharmaceutical Co | Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
| US7402605B2 (en) | 2002-03-05 | 2008-07-22 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient |
| JP2005526080A (ja) * | 2002-03-18 | 2005-09-02 | ファイザー・プロダクツ・インク | 肝不全、動脈管閉鎖、緑内障又は高眼圧の治療のための選択的ｅｐ４受容体アゴニストの使用 |
| JP2006515015A (ja) * | 2003-01-10 | 2006-05-18 | エフ．ホフマン−ラ ロシュ アーゲー | プロスタグランジンアゴニストとしての２−ピペリドン誘導体 |
| US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| US20080058375A1 (en) * | 2004-01-08 | 2008-03-06 | Elworthy Todd R | 2-Piperidone derivatives as prostaglandin antagonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3975399A (en) * | 1974-08-06 | 1976-08-17 | E. I. Du Pont De Nemours And Company | 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones |
-
1976
- 1976-03-31 IL IL49325A patent/IL49325A/xx unknown
-
1977
- 1977-03-28 GB GB12991/77A patent/GB1574246A/en not_active Expired
- 1977-03-28 BE BE176164A patent/BE852941A/xx not_active IP Right Cessation
- 1977-03-29 DD DD7700198124A patent/DD130352A5/xx unknown
- 1977-03-29 PL PL1977210101A patent/PL107544B1/pl unknown
- 1977-03-29 PL PL1977197005A patent/PL107643B1/pl unknown
- 1977-03-29 PL PL1977210102A patent/PL108289B1/pl unknown
- 1977-03-30 HU HU77LA913A patent/HU178040B/hu unknown
- 1977-03-30 CA CA275,134A patent/CA1074804A/en not_active Expired
- 1977-03-30 SE SE7703698A patent/SE417603B/xx unknown
- 1977-03-30 DE DE19772714129 patent/DE2714129A1/de not_active Withdrawn
- 1977-03-30 NO NO771134A patent/NO149428C/no unknown
- 1977-03-30 CH CH400377A patent/CH624101A5/fr not_active IP Right Cessation
- 1977-03-31 US US05/783,284 patent/US4115401A/en not_active Expired - Lifetime
- 1977-03-31 NL NL7703503A patent/NL7703503A/xx not_active Application Discontinuation
- 1977-03-31 JP JP3742877A patent/JPS52142060A/ja active Pending
- 1977-03-31 SU SU772465855A patent/SU676162A3/ru active
- 1977-03-31 IT IT21906/77A patent/IT1075373B/it active
- 1977-03-31 ES ES457385A patent/ES457385A1/es not_active Expired
- 1977-03-31 FR FR7709650A patent/FR2346332A1/fr active Granted
-
1978
- 1978-03-30 SU SU782595450A patent/SU715019A3/ru active
- 1978-03-30 SU SU782594353A patent/SU837321A3/ru active
-
1980
- 1980-09-17 CH CH697780A patent/CH628032A5/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS52142060A (en) | 1977-11-26 |
| BE852941A (fr) | 1977-09-28 |
| IT1075373B (it) | 1985-04-22 |
| US4115401A (en) | 1978-09-19 |
| SE417603B (sv) | 1981-03-30 |
| SU715019A3 (ru) | 1980-02-05 |
| GB1574246A (en) | 1980-09-03 |
| CH628032A5 (fr) | 1982-02-15 |
| SU676162A3 (ru) | 1979-07-25 |
| SU837321A3 (ru) | 1981-06-07 |
| IL49325A (en) | 1979-11-30 |
| IL49325A0 (en) | 1976-05-31 |
| PL107643B1 (pl) | 1980-02-29 |
| PL108289B1 (pl) | 1980-03-31 |
| PL197005A1 (pl) | 1978-10-09 |
| DD130352A5 (de) | 1978-03-22 |
| PL107544B1 (pl) | 1980-02-29 |
| NO149428C (no) | 1984-04-18 |
| NO149428B (no) | 1984-01-09 |
| SE7703698L (sv) | 1977-10-01 |
| CA1074804A (en) | 1980-04-01 |
| NL7703503A (nl) | 1977-10-04 |
| FR2346332A1 (fr) | 1977-10-28 |
| CH624101A5 (en:Method) | 1981-07-15 |
| DE2714129A1 (de) | 1977-10-13 |
| FR2346332B1 (en:Method) | 1980-05-09 |
| NO771134L (no) | 1977-10-03 |
| ES457385A1 (es) | 1978-02-01 |
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