SE417603B - Forfarande for framstellning av derivat av 8-aza-11-deoxiprostaglandin e?711 med terapeutiska egenskaper - Google Patents
Forfarande for framstellning av derivat av 8-aza-11-deoxiprostaglandin e?711 med terapeutiska egenskaperInfo
- Publication number
- SE417603B SE417603B SE7703698A SE7703698A SE417603B SE 417603 B SE417603 B SE 417603B SE 7703698 A SE7703698 A SE 7703698A SE 7703698 A SE7703698 A SE 7703698A SE 417603 B SE417603 B SE 417603B
- Authority
- SE
- Sweden
- Prior art keywords
- deoxiprostaglandin
- aza
- procedure
- preparing derivatives
- therapeutical properties
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/126—Acids containing more than four carbon atoms
- C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL49325A IL49325A (en) | 1976-03-31 | 1976-03-31 | 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7703698L SE7703698L (sv) | 1977-10-01 |
| SE417603B true SE417603B (sv) | 1981-03-30 |
Family
ID=11048789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7703698A SE417603B (sv) | 1976-03-31 | 1977-03-30 | Forfarande for framstellning av derivat av 8-aza-11-deoxiprostaglandin e?711 med terapeutiska egenskaper |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4115401A (sv) |
| JP (1) | JPS52142060A (sv) |
| BE (1) | BE852941A (sv) |
| CA (1) | CA1074804A (sv) |
| CH (2) | CH624101A5 (sv) |
| DD (1) | DD130352A5 (sv) |
| DE (1) | DE2714129A1 (sv) |
| ES (1) | ES457385A1 (sv) |
| FR (1) | FR2346332A1 (sv) |
| GB (1) | GB1574246A (sv) |
| HU (1) | HU178040B (sv) |
| IL (1) | IL49325A (sv) |
| IT (1) | IT1075373B (sv) |
| NL (1) | NL7703503A (sv) |
| NO (1) | NO149428C (sv) |
| PL (3) | PL107544B1 (sv) |
| SE (1) | SE417603B (sv) |
| SU (3) | SU676162A3 (sv) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7905375A (nl) * | 1978-07-11 | 1980-01-15 | Glaxo Group Ltd | Prostanoiden, werkwijze voor het bereiden daarvan, en daarop gebaseerde farmaceutische preparaten. |
| US4320136A (en) * | 1980-08-11 | 1982-03-16 | E. I. Du Pont De Nemours And Company | 8-Aza-16,16-difluoroprostanoids |
| US4456613A (en) * | 1982-12-27 | 1984-06-26 | E. I. Du Pont De Nemours And Company | 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof |
| US4530933A (en) * | 1982-12-27 | 1985-07-23 | E. I. Du Pont De Nemours And Company | 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents |
| CN1413190A (zh) | 1999-12-22 | 2003-04-23 | 辉瑞产品公司 | 治疗骨质疏松的ep4受体选择性激动剂 |
| IL155368A0 (en) * | 2000-11-27 | 2003-11-23 | Pfizer Prod Inc | Ep4 receptor selective agonists in the treatment of osteoporosis |
| EP1408961B1 (en) * | 2001-07-16 | 2007-07-11 | F. Hoffmann-La Roche Ag | 2 pyrrolidone derivatives as prostanoid agonists |
| ES2254726T3 (es) | 2001-07-16 | 2006-06-16 | F. Hoffmann-La Roche Ag | Analogos de prostaglandina como agonistas receptores de ep4. |
| HU230421B1 (hu) | 2001-07-23 | 2016-05-30 | Ono Pharmaceutical Co., Ltd | Csonttömegveszteséggel kapcsolatos betegségek kezelésére adható, EP4 agonistát tartalmazó gyógyászati készítmények és hatóanyagként alkalmazható vegyületek |
| EP1481976B1 (en) | 2002-03-05 | 2012-11-07 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient |
| AU2003209571A1 (en) * | 2002-03-18 | 2003-09-29 | Pfizer Products Inc. | Use of selective ep4 receptor agonists for the treatment of liver failure, loss of patency of the ductus arteriosus, glaucoma or ocular hypertension |
| WO2004063158A1 (en) * | 2003-01-10 | 2004-07-29 | F.Hoffmann-La Roche Ag | 2-piperidone derivatives as prostaglandin agonists |
| US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| US20080058375A1 (en) * | 2004-01-08 | 2008-03-06 | Elworthy Todd R | 2-Piperidone derivatives as prostaglandin antagonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3975399A (en) * | 1974-08-06 | 1976-08-17 | E. I. Du Pont De Nemours And Company | 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones |
-
1976
- 1976-03-31 IL IL49325A patent/IL49325A/xx unknown
-
1977
- 1977-03-28 BE BE176164A patent/BE852941A/xx not_active IP Right Cessation
- 1977-03-28 GB GB12991/77A patent/GB1574246A/en not_active Expired
- 1977-03-29 DD DD7700198124A patent/DD130352A5/xx unknown
- 1977-03-29 PL PL1977210101A patent/PL107544B1/pl unknown
- 1977-03-29 PL PL1977210102A patent/PL108289B1/pl unknown
- 1977-03-29 PL PL1977197005A patent/PL107643B1/pl unknown
- 1977-03-30 CA CA275,134A patent/CA1074804A/en not_active Expired
- 1977-03-30 HU HU77LA913A patent/HU178040B/hu unknown
- 1977-03-30 CH CH400377A patent/CH624101A5/fr not_active IP Right Cessation
- 1977-03-30 SE SE7703698A patent/SE417603B/sv unknown
- 1977-03-30 DE DE19772714129 patent/DE2714129A1/de not_active Withdrawn
- 1977-03-30 NO NO771134A patent/NO149428C/no unknown
- 1977-03-31 JP JP3742877A patent/JPS52142060A/ja active Pending
- 1977-03-31 IT IT21906/77A patent/IT1075373B/it active
- 1977-03-31 FR FR7709650A patent/FR2346332A1/fr active Granted
- 1977-03-31 NL NL7703503A patent/NL7703503A/xx not_active Application Discontinuation
- 1977-03-31 ES ES457385A patent/ES457385A1/es not_active Expired
- 1977-03-31 SU SU772465855A patent/SU676162A3/ru active
- 1977-03-31 US US05/783,284 patent/US4115401A/en not_active Expired - Lifetime
-
1978
- 1978-03-30 SU SU782595450A patent/SU715019A3/ru active
- 1978-03-30 SU SU782594353A patent/SU837321A3/ru active
-
1980
- 1980-09-17 CH CH697780A patent/CH628032A5/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB1574246A (en) | 1980-09-03 |
| FR2346332B1 (sv) | 1980-05-09 |
| PL108289B1 (pl) | 1980-03-31 |
| SE7703698L (sv) | 1977-10-01 |
| PL197005A1 (pl) | 1978-10-09 |
| CH628032A5 (fr) | 1982-02-15 |
| BE852941A (fr) | 1977-09-28 |
| NL7703503A (nl) | 1977-10-04 |
| ES457385A1 (es) | 1978-02-01 |
| FR2346332A1 (fr) | 1977-10-28 |
| NO149428C (no) | 1984-04-18 |
| PL107643B1 (pl) | 1980-02-29 |
| JPS52142060A (en) | 1977-11-26 |
| DE2714129A1 (de) | 1977-10-13 |
| PL107544B1 (pl) | 1980-02-29 |
| CA1074804A (en) | 1980-04-01 |
| NO149428B (no) | 1984-01-09 |
| DD130352A5 (de) | 1978-03-22 |
| SU837321A3 (ru) | 1981-06-07 |
| IT1075373B (it) | 1985-04-22 |
| SU715019A3 (ru) | 1980-02-05 |
| US4115401A (en) | 1978-09-19 |
| SU676162A3 (ru) | 1979-07-25 |
| IL49325A0 (en) | 1976-05-31 |
| NO771134L (no) | 1977-10-03 |
| CH624101A5 (sv) | 1981-07-15 |
| IL49325A (en) | 1979-11-30 |
| HU178040B (en) | 1982-02-28 |
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