NO149209C - Analogifremgangsmaate til fremstilling av terapeutisk aktive 1-(3-(3,4,5-trimetoksyfenoksy)-2-hydroksypropyl))-4-aryl-piperazin-derivater - Google Patents
Analogifremgangsmaate til fremstilling av terapeutisk aktive 1-(3-(3,4,5-trimetoksyfenoksy)-2-hydroksypropyl))-4-aryl-piperazin-derivaterInfo
- Publication number
- NO149209C NO149209C NO781159A NO781159A NO149209C NO 149209 C NO149209 C NO 149209C NO 781159 A NO781159 A NO 781159A NO 781159 A NO781159 A NO 781159A NO 149209 C NO149209 C NO 149209C
- Authority
- NO
- Norway
- Prior art keywords
- trimetoxyphenoxy
- hydroxypropyl
- aryl
- preparation
- piperazine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB14100/77A GB1583372A (en) | 1977-04-04 | 1977-04-04 | 1-(3-(3,4,5-trimethoxyphenoxy)-2-hydroxypropyl)-4-aryl piperazine derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO781159L NO781159L (no) | 1978-10-05 |
| NO149209B NO149209B (no) | 1983-11-28 |
| NO149209C true NO149209C (no) | 1984-03-07 |
Family
ID=10034980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO781159A NO149209C (no) | 1977-04-04 | 1978-04-03 | Analogifremgangsmaate til fremstilling av terapeutisk aktive 1-(3-(3,4,5-trimetoksyfenoksy)-2-hydroksypropyl))-4-aryl-piperazin-derivater |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS6038383B2 (sv) |
| AR (1) | AR222149A1 (sv) |
| AT (1) | AT360997B (sv) |
| AU (1) | AU516315B2 (sv) |
| BE (1) | BE865642A (sv) |
| CA (1) | CA1124718A (sv) |
| CH (1) | CH638795A5 (sv) |
| CS (1) | CS249503B2 (sv) |
| DE (1) | DE2814168A1 (sv) |
| DK (1) | DK145225C (sv) |
| ES (1) | ES468486A1 (sv) |
| FI (1) | FI69627C (sv) |
| FR (1) | FR2395264A1 (sv) |
| GB (1) | GB1583372A (sv) |
| HU (1) | HU179952B (sv) |
| MX (1) | MX6120E (sv) |
| NL (1) | NL7803540A (sv) |
| NO (1) | NO149209C (sv) |
| PL (1) | PL112249B1 (sv) |
| SE (1) | SE435507B (sv) |
| SU (1) | SU893133A3 (sv) |
| YU (1) | YU40513B (sv) |
| ZA (1) | ZA781889B (sv) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4335126A (en) * | 1977-03-10 | 1982-06-15 | Degussa Aktiengesellschaft | 1-[3-(3,4,5-Trimethoxyphenoxy)-2-hydroxy-propyl]-4-aryl-piperazine-derivatives having pharmaceutical activity |
| FR2488892A2 (fr) * | 1977-04-04 | 1982-02-26 | Degussa | Nouveaux derives 1-(3-(3,4,5-trimethoxyphenoxy)-2-hydroxypropyl)-4-aryl-piperaziniques, procede pour leur preparation et leur application en tant que medicament |
| DE2824764A1 (de) * | 1978-06-06 | 1979-12-20 | Hoechst Ag | Neue pyridylpiperazinderivate und verfahren zu ihrer herstellung |
| DE3023369A1 (de) * | 1980-06-23 | 1982-01-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Aryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| FR2568878B1 (fr) * | 1984-08-07 | 1986-11-21 | Cortial | Nouveaux derives de (phenylpiperazinylethylamine ethoxy)-4 phenol, leur methode de preparation et leur application therapeutique |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA967965A (en) * | 1968-12-24 | 1975-05-20 | Hoffmann-La Roche Limited | Aromatic ethers and process for the manufacture thereof |
| FR2068051A5 (sv) * | 1969-11-26 | 1971-08-20 | Robert Jean | |
| CA1012540A (en) * | 1972-06-17 | 1977-06-21 | Sumitomo Chemical Company | 2-propanol derivatives and preparation thereof |
| DE2235597A1 (de) * | 1972-07-20 | 1974-01-31 | Boehringer Mannheim Gmbh | 1-eckige klammer auf 3-(5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl eckige klammer zu -piperazin-derivate und verfahren zu ihrer herstellung |
-
1977
- 1977-04-04 GB GB14100/77A patent/GB1583372A/en not_active Expired
-
1978
- 1978-03-31 YU YU767/78A patent/YU40513B/xx unknown
- 1978-03-31 FR FR7809675A patent/FR2395264A1/fr active Granted
- 1978-04-01 HU HU78DE957A patent/HU179952B/hu not_active IP Right Cessation
- 1978-04-01 PL PL1978205745A patent/PL112249B1/pl unknown
- 1978-04-01 DE DE19782814168 patent/DE2814168A1/de active Granted
- 1978-04-03 CA CA300,288A patent/CA1124718A/en not_active Expired
- 1978-04-03 ZA ZA00781889A patent/ZA781889B/xx unknown
- 1978-04-03 AT AT233078A patent/AT360997B/de not_active IP Right Cessation
- 1978-04-03 FI FI781009A patent/FI69627C/fi not_active IP Right Cessation
- 1978-04-03 CH CH354378A patent/CH638795A5/de not_active IP Right Cessation
- 1978-04-03 BE BE6046420A patent/BE865642A/xx not_active IP Right Cessation
- 1978-04-03 NL NL7803540A patent/NL7803540A/xx not_active Application Discontinuation
- 1978-04-03 SU SU782596099A patent/SU893133A3/ru active
- 1978-04-03 SE SE7803742A patent/SE435507B/sv not_active IP Right Cessation
- 1978-04-03 NO NO781159A patent/NO149209C/no unknown
- 1978-04-03 AU AU34703/78A patent/AU516315B2/en not_active Expired
- 1978-04-03 DK DK146678A patent/DK145225C/da not_active IP Right Cessation
- 1978-04-03 ES ES468486A patent/ES468486A1/es not_active Expired
- 1978-04-03 CS CS782141A patent/CS249503B2/cs unknown
- 1978-04-04 AR AR271686A patent/AR222149A1/es active
- 1978-04-04 MX MX786995U patent/MX6120E/es unknown
- 1978-04-04 JP JP53039626A patent/JPS6038383B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT360997B (de) | 1981-02-10 |
| DK146678A (da) | 1978-10-05 |
| DK145225B (da) | 1982-10-11 |
| FI781009A (fi) | 1978-10-05 |
| GB1583372A (en) | 1981-01-28 |
| NO149209B (no) | 1983-11-28 |
| MX6120E (es) | 1984-11-19 |
| SE7803742L (sv) | 1978-10-05 |
| PL112249B1 (en) | 1980-10-31 |
| SU893133A3 (ru) | 1981-12-23 |
| YU40513B (en) | 1986-02-28 |
| CH638795A5 (en) | 1983-10-14 |
| JPS53130682A (en) | 1978-11-14 |
| PL205745A1 (pl) | 1979-05-07 |
| FI69627B (fi) | 1985-11-29 |
| AU3470378A (en) | 1979-10-11 |
| BE865642A (fr) | 1978-10-03 |
| ZA781889B (en) | 1979-03-28 |
| FI69627C (fi) | 1986-03-10 |
| DK145225C (da) | 1983-04-11 |
| YU76778A (en) | 1982-10-31 |
| FR2395264B1 (sv) | 1980-03-07 |
| FR2395264A1 (fr) | 1979-01-19 |
| SE435507B (sv) | 1984-10-01 |
| CA1124718A (en) | 1982-06-01 |
| DE2814168A1 (de) | 1978-10-05 |
| ATA233078A (de) | 1980-07-15 |
| HU179952B (en) | 1983-01-28 |
| AU516315B2 (en) | 1981-05-28 |
| CS249503B2 (en) | 1987-03-12 |
| NO781159L (no) | 1978-10-05 |
| AR222149A1 (es) | 1981-04-30 |
| DE2814168C2 (sv) | 1989-02-16 |
| JPS6038383B2 (ja) | 1985-08-31 |
| ES468486A1 (es) | 1979-01-16 |
| NL7803540A (nl) | 1978-10-06 |
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