NO146698C - Fremgangsmaate for fremstilling av et stabilt langtidsvirkende insulinprodukt. - Google Patents

Fremgangsmaate for fremstilling av et stabilt langtidsvirkende insulinprodukt.

Info

Publication number
NO146698C
NO146698C NO760118A NO760118A NO146698C NO 146698 C NO146698 C NO 146698C NO 760118 A NO760118 A NO 760118A NO 760118 A NO760118 A NO 760118A NO 146698 C NO146698 C NO 146698C
Authority
NO
Norway
Prior art keywords
preparing
procedure
stable long
insulin product
effective insulin
Prior art date
Application number
NO760118A
Other languages
English (en)
Other versions
NO760118L (no
NO146698B (no
Inventor
Bruno Andre Hansen
Finn Hede Andresen
Original Assignee
Nordisk Insulinlab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Insulinlab filed Critical Nordisk Insulinlab
Publication of NO760118L publication Critical patent/NO760118L/no
Publication of NO146698B publication Critical patent/NO146698B/no
Publication of NO146698C publication Critical patent/NO146698C/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • C07K14/625Extraction from natural sources
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO760118A 1975-01-15 1976-01-14 Fremgangsmaate for fremstilling av et stabilt langtidsvirkende insulinprodukt. NO146698C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK8375AA DK140801B (da) 1975-01-15 1975-01-15 Fremgangsmåde til fremstilling af et stabilt langtidsvirkende insulinpræparat.

Publications (3)

Publication Number Publication Date
NO760118L NO760118L (no) 1976-07-16
NO146698B NO146698B (no) 1982-08-16
NO146698C true NO146698C (no) 1982-11-24

Family

ID=8089535

Family Applications (1)

Application Number Title Priority Date Filing Date
NO760118A NO146698C (no) 1975-01-15 1976-01-14 Fremgangsmaate for fremstilling av et stabilt langtidsvirkende insulinprodukt.

Country Status (36)

Country Link
JP (1) JPS5946939B2 (no)
AR (1) AR213088A1 (no)
AT (1) AT362492B (no)
BE (1) BE837600A (no)
BR (1) BR7600206A (no)
CA (1) CA1094549A (no)
CH (1) CH631625A5 (no)
CS (1) CS208147B2 (no)
DD (1) DD124379A5 (no)
DE (1) DE2600971C2 (no)
DK (1) DK140801B (no)
EG (1) EG11988A (no)
ES (1) ES444558A1 (no)
FI (1) FI66751C (no)
FR (1) FR2297634A1 (no)
GB (1) GB1524431A (no)
GR (1) GR58608B (no)
HU (1) HU175142B (no)
IE (1) IE42395B1 (no)
IL (1) IL48845A (no)
IN (1) IN143279B (no)
IT (1) IT1054211B (no)
KE (1) KE2919A (no)
LU (1) LU74175A1 (no)
MX (1) MX4052E (no)
MY (1) MY7900169A (no)
NL (1) NL166464C (no)
NO (1) NO146698C (no)
NZ (1) NZ179733A (no)
OA (1) OA05209A (no)
PL (1) PL99927B1 (no)
PT (1) PT64696B (no)
RO (1) RO71576A (no)
SE (1) SE437219B (no)
YU (1) YU8376A (no)
ZA (1) ZA7658B (no)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447728A (en) 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US6071538A (en) 1992-06-15 2000-06-06 Emisphere Technologies, Inc. Oral delivery composition comprising supramolecular complex
US6100298A (en) 1993-04-22 2000-08-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6100285A (en) 1995-06-07 2000-08-08 Emisphere Technologies, Inc. Method of solubilizing itraconazole
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK374579A (da) * 1979-09-07 1981-03-08 Nordisk Insulinlab Fremgangsmaade til fremstilling af et injucerbart insulinpraeparat
US4459226A (en) * 1982-02-26 1984-07-10 Eli Lilly And Company Process for recovering insulin
US4801575A (en) * 1986-07-30 1989-01-31 The Regents Of The University Of California Chimeric peptides for neuropeptide delivery through the blood-brain barrier
AU609769B2 (en) * 1987-02-10 1991-05-09 Drug Delivery Systems Inc. Electrolytic transdermal delivery of proteins
US4878892A (en) * 1987-02-10 1989-11-07 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
JP5763053B2 (ja) 2009-05-18 2015-08-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アダプタ、吸入器具及びアトマイザ
EP2504052B1 (en) 2009-11-25 2022-07-27 Boehringer Ingelheim International GmbH Nebulizer
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
JP5874724B2 (ja) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
PL2835146T3 (pl) 2013-08-09 2021-04-06 Boehringer Ingelheim International Gmbh Nebulizator
DK3139984T3 (da) 2014-05-07 2021-07-19 Boehringer Ingelheim Int Forstøver
EP3139979B1 (en) 2014-05-07 2023-07-05 Boehringer Ingelheim International GmbH Unit, nebulizer and method
HUE058904T2 (hu) 2014-05-07 2022-09-28 Boehringer Ingelheim Int Porlasztókészülék

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1285023A (en) * 1968-08-09 1972-08-09 Novo Terapeutisk Labor As Improvements in or relating to injectable insulin preparations
US3758683A (en) * 1971-04-30 1973-09-11 R Jackson Insulin product

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447728A (en) 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US6071538A (en) 1992-06-15 2000-06-06 Emisphere Technologies, Inc. Oral delivery composition comprising supramolecular complex
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US6245359B1 (en) 1992-06-15 2001-06-12 Emisphere Technologies, Inc. Active agent transport systems
US6100298A (en) 1993-04-22 2000-08-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5935601A (en) * 1994-04-22 1999-08-10 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US6100285A (en) 1995-06-07 2000-08-08 Emisphere Technologies, Inc. Method of solubilizing itraconazole

Also Published As

Publication number Publication date
IE42395B1 (en) 1980-07-30
NL166464B (nl) 1981-03-16
DE2600971C2 (de) 1985-12-12
PT64696B (fr) 1977-08-10
GR58608B (en) 1977-11-10
ES444558A1 (es) 1977-05-16
IE42395L (en) 1976-07-15
DD124379A5 (no) 1977-02-16
OA05209A (fr) 1981-02-28
BE837600A (fr) 1976-07-15
PT64696A (fr) 1976-02-01
IN143279B (no) 1977-10-29
ZA7658B (en) 1976-12-29
DK8375A (no) 1976-07-16
CA1094549A (en) 1981-01-27
AU1030776A (en) 1977-07-21
NL166464C (nl) 1981-08-17
EG11988A (en) 1978-06-30
MX4052E (es) 1981-11-24
FI66751C (fi) 1984-12-10
MY7900169A (en) 1979-12-31
BR7600206A (pt) 1976-08-31
NZ179733A (en) 1978-04-28
RO71576A (ro) 1980-12-30
AR213088A1 (es) 1978-12-15
SE437219B (sv) 1985-02-18
JPS51125299A (en) 1976-11-01
JPS5946939B2 (ja) 1984-11-15
KE2919A (en) 1979-03-30
LU74175A1 (no) 1977-03-18
AT362492B (de) 1981-05-25
DK140801B (da) 1979-11-19
FI760058A (no) 1976-07-16
NL7600338A (nl) 1976-07-19
IL48845A0 (en) 1976-03-31
CS208147B2 (en) 1981-08-31
FR2297634B1 (no) 1979-03-30
NO760118L (no) 1976-07-16
IT1054211B (it) 1981-11-10
ATA21376A (de) 1980-10-15
HU175142B (hu) 1980-05-28
SE7600284L (sv) 1976-07-16
FR2297634A1 (fr) 1976-08-13
PL99927B1 (pl) 1978-08-31
IL48845A (en) 1981-06-29
FI66751B (fi) 1984-08-31
GB1524431A (en) 1978-09-13
DE2600971A1 (de) 1976-07-22
CH631625A5 (en) 1982-08-31
DK140801C (no) 1980-04-21
YU8376A (en) 1982-06-30
NO146698B (no) 1982-08-16

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