FR2297634A1 - Procede de production d'une preparation therapeutique stable d'insuline et produit obtenu - Google Patents

Procede de production d'une preparation therapeutique stable d'insuline et produit obtenu

Info

Publication number
FR2297634A1
FR2297634A1 FR7600854A FR7600854A FR2297634A1 FR 2297634 A1 FR2297634 A1 FR 2297634A1 FR 7600854 A FR7600854 A FR 7600854A FR 7600854 A FR7600854 A FR 7600854A FR 2297634 A1 FR2297634 A1 FR 2297634A1
Authority
FR
France
Prior art keywords
insulin
producing
product obtained
therapeutic preparation
stable therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7600854A
Other languages
English (en)
Other versions
FR2297634B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nordisk Insulinlaboratorium
Original Assignee
Nordisk Insulinlaboratorium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Insulinlaboratorium filed Critical Nordisk Insulinlaboratorium
Publication of FR2297634A1 publication Critical patent/FR2297634A1/fr
Application granted granted Critical
Publication of FR2297634B1 publication Critical patent/FR2297634B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C07K14/625—Extraction from natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR7600854A 1975-01-15 1976-01-14 Procede de production d'une preparation therapeutique stable d'insuline et produit obtenu Granted FR2297634A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK8375AA DK140801B (da) 1975-01-15 1975-01-15 Fremgangsmåde til fremstilling af et stabilt langtidsvirkende insulinpræparat.

Publications (2)

Publication Number Publication Date
FR2297634A1 true FR2297634A1 (fr) 1976-08-13
FR2297634B1 FR2297634B1 (fr) 1979-03-30

Family

ID=8089535

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7600854A Granted FR2297634A1 (fr) 1975-01-15 1976-01-14 Procede de production d'une preparation therapeutique stable d'insuline et produit obtenu

Country Status (36)

Country Link
JP (1) JPS5946939B2 (fr)
AR (1) AR213088A1 (fr)
AT (1) AT362492B (fr)
BE (1) BE837600A (fr)
BR (1) BR7600206A (fr)
CA (1) CA1094549A (fr)
CH (1) CH631625A5 (fr)
CS (1) CS208147B2 (fr)
DD (1) DD124379A5 (fr)
DE (1) DE2600971C2 (fr)
DK (1) DK140801B (fr)
EG (1) EG11988A (fr)
ES (1) ES444558A1 (fr)
FI (1) FI66751C (fr)
FR (1) FR2297634A1 (fr)
GB (1) GB1524431A (fr)
GR (1) GR58608B (fr)
HU (1) HU175142B (fr)
IE (1) IE42395B1 (fr)
IL (1) IL48845A (fr)
IN (1) IN143279B (fr)
IT (1) IT1054211B (fr)
KE (1) KE2919A (fr)
LU (1) LU74175A1 (fr)
MX (1) MX4052E (fr)
MY (1) MY7900169A (fr)
NL (1) NL166464C (fr)
NO (1) NO146698C (fr)
NZ (1) NZ179733A (fr)
OA (1) OA05209A (fr)
PL (1) PL99927B1 (fr)
PT (1) PT64696B (fr)
RO (1) RO71576A (fr)
SE (1) SE437219B (fr)
YU (1) YU8376A (fr)
ZA (1) ZA7658B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK374579A (da) * 1979-09-07 1981-03-08 Nordisk Insulinlab Fremgangsmaade til fremstilling af et injucerbart insulinpraeparat
US4459226A (en) * 1982-02-26 1984-07-10 Eli Lilly And Company Process for recovering insulin
US4801575A (en) * 1986-07-30 1989-01-31 The Regents Of The University Of California Chimeric peptides for neuropeptide delivery through the blood-brain barrier
AU609769B2 (en) * 1987-02-10 1991-05-09 Drug Delivery Systems Inc. Electrolytic transdermal delivery of proteins
US4878892A (en) * 1987-02-10 1989-11-07 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5629020A (en) * 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5447728A (en) 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5643957A (en) 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
EP2077132A1 (fr) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur, dispositif de stockage et procédé pour la distribution d'une formulation
EP2414560B1 (fr) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Procédé de revêtement d'une surface d'un composant
JP5763053B2 (ja) 2009-05-18 2015-08-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アダプタ、吸入器具及びアトマイザ
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064164A1 (fr) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nébuliseur
WO2011160932A1 (fr) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nébuliseur
WO2012130757A1 (fr) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Appareil médical pourvu d'un récipient
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (fr) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Pulvérisateur comprenant des moyens de détrompage
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2835146B1 (fr) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Atomiseur
LT3928818T (lt) 2014-05-07 2023-03-27 Boehringer Ingelheim International Gmbh Purkštuvas ir talpa
JP6580070B2 (ja) 2014-05-07 2019-09-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 容器、ネブライザ、及び使用
PL3139984T3 (pl) 2014-05-07 2021-11-08 Boehringer Ingelheim International Gmbh Nebulizator

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1285023A (en) * 1968-08-09 1972-08-09 Novo Terapeutisk Labor As Improvements in or relating to injectable insulin preparations
US3758683A (en) * 1971-04-30 1973-09-11 R Jackson Insulin product

Also Published As

Publication number Publication date
DK8375A (fr) 1976-07-16
BR7600206A (pt) 1976-08-31
SE437219B (sv) 1985-02-18
NL166464B (nl) 1981-03-16
ZA7658B (en) 1976-12-29
NZ179733A (en) 1978-04-28
AT362492B (de) 1981-05-25
EG11988A (en) 1978-06-30
MY7900169A (en) 1979-12-31
DE2600971A1 (de) 1976-07-22
FI66751C (fi) 1984-12-10
BE837600A (fr) 1976-07-15
LU74175A1 (fr) 1977-03-18
DE2600971C2 (de) 1985-12-12
FI760058A (fr) 1976-07-16
IL48845A0 (en) 1976-03-31
PL99927B1 (pl) 1978-08-31
ATA21376A (de) 1980-10-15
CA1094549A (fr) 1981-01-27
CH631625A5 (en) 1982-08-31
RO71576A (fr) 1980-12-30
FR2297634B1 (fr) 1979-03-30
MX4052E (es) 1981-11-24
CS208147B2 (en) 1981-08-31
HU175142B (hu) 1980-05-28
GB1524431A (en) 1978-09-13
DK140801B (da) 1979-11-19
AU1030776A (en) 1977-07-21
JPS51125299A (en) 1976-11-01
JPS5946939B2 (ja) 1984-11-15
NL7600338A (nl) 1976-07-19
NO760118L (fr) 1976-07-16
DD124379A5 (fr) 1977-02-16
PT64696B (fr) 1977-08-10
ES444558A1 (es) 1977-05-16
NO146698C (no) 1982-11-24
NL166464C (nl) 1981-08-17
SE7600284L (sv) 1976-07-16
YU8376A (en) 1982-06-30
GR58608B (en) 1977-11-10
DK140801C (fr) 1980-04-21
IT1054211B (it) 1981-11-10
IL48845A (en) 1981-06-29
PT64696A (fr) 1976-02-01
IE42395L (en) 1976-07-15
AR213088A1 (es) 1978-12-15
IN143279B (fr) 1977-10-29
NO146698B (no) 1982-08-16
FI66751B (fi) 1984-08-31
OA05209A (fr) 1981-02-28
KE2919A (en) 1979-03-30
IE42395B1 (en) 1980-07-30

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Legal Events

Date Code Title Description
ST Notification of lapse