NO146599C - Analogifremgangsmaate ved fremstilling av terapeutisk aktivt 6-klor-2-(1`-piperazinyl)-pyrazin og salter derav - Google Patents
Analogifremgangsmaate ved fremstilling av terapeutisk aktivt 6-klor-2-(1`-piperazinyl)-pyrazin og salter deravInfo
- Publication number
- NO146599C NO146599C NO761207A NO761207A NO146599C NO 146599 C NO146599 C NO 146599C NO 761207 A NO761207 A NO 761207A NO 761207 A NO761207 A NO 761207A NO 146599 C NO146599 C NO 146599C
- Authority
- NO
- Norway
- Prior art keywords
- pyrazine
- piperazinyl
- chloro
- salts
- preparation
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57005275A | 1975-04-21 | 1975-04-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO761207L NO761207L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-10-22 |
| NO146599B NO146599B (no) | 1982-07-26 |
| NO146599C true NO146599C (no) | 1982-11-03 |
Family
ID=24277994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO761207A NO146599C (no) | 1975-04-21 | 1976-04-08 | Analogifremgangsmaate ved fremstilling av terapeutisk aktivt 6-klor-2-(1`-piperazinyl)-pyrazin og salter derav |
Country Status (36)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091098A (en) * | 1977-04-25 | 1978-05-23 | Merck & Co., Inc. | 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides |
| US4163849A (en) | 1978-03-17 | 1979-08-07 | Merck & Co., Inc. | Piperazinylpyrazines |
| US4252816A (en) * | 1979-12-03 | 1981-02-24 | Merck & Co., Inc. | Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents |
| US4339579A (en) | 1980-12-29 | 1982-07-13 | American Home Products Corporation | 2,6-Bis-(pyrrolopyrazinyl)pyrazines |
| EP0094498A3 (en) * | 1982-05-06 | 1985-04-03 | American Cyanamid Company | Antiatherosclerotic 1-piperazine derivatives |
| US4547505A (en) * | 1983-03-25 | 1985-10-15 | Degussa Aktiengesellschaft | N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production |
| US4788290A (en) * | 1987-12-11 | 1988-11-29 | American Home Products Corporation | Serotonergic pyrazine derivatives |
| EP0580465A1 (fr) * | 1992-06-25 | 1994-01-26 | Sanofi | Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés |
| CA2306093C (en) | 1997-10-27 | 2011-01-04 | Neurosearch A/S | Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors |
| EP1175416B1 (en) * | 1999-04-26 | 2003-07-16 | Neurosearch A/S | Heteroaryl diazacycloalkanes, their preparation and use |
| SK11542002A3 (sk) * | 2000-02-16 | 2003-03-04 | Neurogen Corporation | Substituované arylpyrazíny |
| US6825198B2 (en) * | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
| NZ537629A (en) * | 2002-07-19 | 2007-05-31 | Biovitrum Ab | Novel piperazinyl-pyrazinone derivatives for the treatment of 5-HT2A receptor-related disorders |
| SE0202287D0 (sv) * | 2002-07-19 | 2002-07-19 | Biovitrum Ab | New compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2606906A (en) * | 1948-10-14 | 1952-08-12 | American Cyanamid Co | 1-(2-pyridyl) piperazine and process of preparing same |
-
1976
- 1976-04-07 SE SE7604093A patent/SE421695B/xx not_active IP Right Cessation
- 1976-04-07 EG EG76205A patent/EG12387A/xx active
- 1976-04-07 DK DK164476A patent/DK143899C/da not_active IP Right Cessation
- 1976-04-08 NO NO761207A patent/NO146599C/no unknown
- 1976-04-09 NL NL7603800A patent/NL167692C/xx not_active IP Right Cessation
- 1976-04-09 FI FI760978A patent/FI62666C/fi not_active IP Right Cessation
- 1976-04-12 IL IL49391A patent/IL49391A/xx unknown
- 1976-04-13 PH PH18329A patent/PH12274A/en unknown
- 1976-04-13 AU AU12966/76A patent/AU496854B2/en not_active Expired
- 1976-04-13 GR GR50538A patent/GR59900B/el unknown
- 1976-04-14 FR FR7610958A patent/FR2308367A1/fr active Granted
- 1976-04-14 CA CA250,732A patent/CA1059128A/en not_active Expired
- 1976-04-15 GB GB15644/76A patent/GB1492528A/en not_active Expired
- 1976-04-15 CY CY1090A patent/CY1090A/xx unknown
- 1976-04-15 DD DD192399A patent/DD124599A5/xx unknown
- 1976-04-16 CS CS762549A patent/CS195726B2/cs unknown
- 1976-04-19 ES ES447150A patent/ES447150A1/es not_active Expired
- 1976-04-19 JP JP51043763A patent/JPS51136688A/ja active Granted
- 1976-04-20 PL PL1976188912A patent/PL99664B1/pl unknown
- 1976-04-20 YU YU01006/76A patent/YU100676A/xx unknown
- 1976-04-20 AT AT288376A patent/AT353795B/de not_active IP Right Cessation
- 1976-04-20 BE BE166282A patent/BE840904A/xx not_active IP Right Cessation
- 1976-04-20 LU LU74795A patent/LU74795A1/xx unknown
- 1976-04-20 SU SU762346054A patent/SU638260A3/ru active
- 1976-04-20 DE DE2617205A patent/DE2617205C3/de not_active Expired
- 1976-04-20 CH CH492676A patent/CH619462A5/de not_active IP Right Cessation
- 1976-04-20 AR AR262930A patent/AR210349A1/es active
- 1976-04-20 RO RO7685688A patent/RO73278A/ro unknown
- 1976-04-20 BG BG032968A patent/BG34185A3/xx unknown
- 1976-04-20 ZA ZA762320A patent/ZA762320B/xx unknown
- 1976-04-21 IE IE828/76A patent/IE42979B1/en unknown
- 1976-04-21 HU HU76ME00001967A patent/HU172684B/hu unknown
- 1976-04-21 PT PT65027A patent/PT65027B/pt unknown
-
1977
- 1977-06-01 ES ES459407A patent/ES459407A1/es not_active Expired
- 1977-06-01 ES ES459406A patent/ES459406A1/es not_active Expired
- 1977-06-01 ES ES459405A patent/ES459405A1/es not_active Expired
-
1980
- 1980-10-02 KE KE3088A patent/KE3088A/xx unknown
- 1980-10-30 HK HK603/80A patent/HK60380A/xx unknown
-
1981
- 1981-12-30 MY MY225/81A patent/MY8100225A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO150361C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive 3-(1h-tetrazol-5-yl)-4h-(pyrido-(1,2-a)-pyrimidin-4-on-derivater | |
| NO143219C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive forbindelser. | |
| NO151321C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater | |
| NO151463C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater | |
| NO784397L (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalazin-4-yl-eddiksyrederivater | |
| NO149102C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive trans-4-fenyl-1,2,3,4-tetrahydro-1-naftalenamin-derivater | |
| NO155774C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazo-diazepin-derivater. | |
| NO155055C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive beta-carbolin-3-carboxylsyrederivater. | |
| NO773384L (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-aryloksy-2-hydroksy-3-alkylenaminopropan-derivater | |
| NO150760C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive aminotiazoler. | |
| NO147104C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive acetylenderivater av aminosyrer | |
| NO800881L (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolonderivater | |
| NO146599C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktivt 6-klor-2-(1`-piperazinyl)-pyrazin og salter derav | |
| NO146865C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 16-dehydro-androstanderivater | |
| NO144926C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive 1-benzazolylalkyl-4-substituerte piperidiner | |
| NO782756L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive antrakinonderivater | |
| NO152005C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksylsyrederivater | |
| NO146359C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive cyproheptadinderivater | |
| NO151319C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive beta-mono-fluormetyl-beta-alanin- og beta-difluormetyl-beta-alanin-forbindelser | |
| NO147750C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive og optisk aktive 11-desoksy-16-aryloksy-omega-tetranorprostaglandiner | |
| NO781879L (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridobenzodiazepiner | |
| NO141014C (no) | Analogifremgangsmaate for fremstilling av farmakologisk aktive 9-alkylamino-erytromyciner og deres salter | |
| NO152128C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive 2-amino-3-benzoylfenylacetamider | |
| NO152605C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-pyridyl- og 2-pyrimidylaminobenzoesyrer | |
| NO145950C (no) | Analogifremgangsmaate for fremstilling av farmakologisk aktive homoftalimider |