EG12387A - Process for preparing of piperazinyl pyrazines - Google Patents
Process for preparing of piperazinyl pyrazinesInfo
- Publication number
- EG12387A EG12387A EG76205A EG20576A EG12387A EG 12387 A EG12387 A EG 12387A EG 76205 A EG76205 A EG 76205A EG 20576 A EG20576 A EG 20576A EG 12387 A EG12387 A EG 12387A
- Authority
- EG
- Egypt
- Prior art keywords
- preparing
- pyrazines
- piperazinyl
- piperazinyl pyrazines
- Prior art date
Links
- HCGFLVDMFDHYJD-UHFFFAOYSA-N 2-piperazin-1-ylpyrazine Chemical class C1CNCCN1C1=CN=CC=N1 HCGFLVDMFDHYJD-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57005275A | 1975-04-21 | 1975-04-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
EG12387A true EG12387A (en) | 1978-12-31 |
Family
ID=24277994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EG76205A EG12387A (en) | 1975-04-21 | 1976-04-07 | Process for preparing of piperazinyl pyrazines |
Country Status (36)
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4091098A (en) * | 1977-04-25 | 1978-05-23 | Merck & Co., Inc. | 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides |
US4163849A (en) | 1978-03-17 | 1979-08-07 | Merck & Co., Inc. | Piperazinylpyrazines |
US4252816A (en) * | 1979-12-03 | 1981-02-24 | Merck & Co., Inc. | Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents |
US4339579A (en) | 1980-12-29 | 1982-07-13 | American Home Products Corporation | 2,6-Bis-(pyrrolopyrazinyl)pyrazines |
EP0094498A3 (en) * | 1982-05-06 | 1985-04-03 | American Cyanamid Company | Antiatherosclerotic 1-piperazine derivatives |
US4547505A (en) * | 1983-03-25 | 1985-10-15 | Degussa Aktiengesellschaft | N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production |
US4788290A (en) * | 1987-12-11 | 1988-11-29 | American Home Products Corporation | Serotonergic pyrazine derivatives |
EP0580465A1 (fr) * | 1992-06-25 | 1994-01-26 | Sanofi | Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés |
HU226859B1 (en) * | 1997-10-27 | 2009-12-28 | Neurosearch As | Phenyl- or heteroaryl-homopiperazines, their use and medicaments containing them |
WO2000064885A1 (en) * | 1999-04-26 | 2000-11-02 | Neurosearch A/S | Heteroaryl diazacycloalkanes, their preparation and use |
IL151020A0 (en) * | 2000-02-16 | 2003-02-12 | Neurogen Corp | Substituted arylpyrazines |
US6825198B2 (en) * | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
CN1305871C (zh) | 2002-07-19 | 2007-03-21 | 比奥维特罗姆股份公司 | 用于治疗与5-ht2a受体有关疾病的新哌嗪基-吡嗪酮衍生物 |
SE0202287D0 (sv) * | 2002-07-19 | 2002-07-19 | Biovitrum Ab | New compounds |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2606906A (en) * | 1948-10-14 | 1952-08-12 | American Cyanamid Co | 1-(2-pyridyl) piperazine and process of preparing same |
-
1976
- 1976-04-07 SE SE7604093A patent/SE421695B/xx not_active IP Right Cessation
- 1976-04-07 EG EG76205A patent/EG12387A/xx active
- 1976-04-07 DK DK164476A patent/DK143899C/da not_active IP Right Cessation
- 1976-04-08 NO NO761207A patent/NO146599C/no unknown
- 1976-04-09 FI FI760978A patent/FI62666C/fi not_active IP Right Cessation
- 1976-04-09 NL NL7603800A patent/NL167692C/xx not_active IP Right Cessation
- 1976-04-12 IL IL49391A patent/IL49391A/xx unknown
- 1976-04-13 GR GR50538A patent/GR59900B/el unknown
- 1976-04-13 AU AU12966/76A patent/AU496854B2/en not_active Expired
- 1976-04-13 PH PH18329A patent/PH12274A/en unknown
- 1976-04-14 CA CA250,732A patent/CA1059128A/en not_active Expired
- 1976-04-14 FR FR7610958A patent/FR2308367A1/fr active Granted
- 1976-04-15 GB GB15644/76A patent/GB1492528A/en not_active Expired
- 1976-04-15 CY CY1090A patent/CY1090A/xx unknown
- 1976-04-15 DD DD192399A patent/DD124599A5/xx unknown
- 1976-04-16 CS CS762549A patent/CS195726B2/cs unknown
- 1976-04-19 ES ES447150A patent/ES447150A1/es not_active Expired
- 1976-04-19 JP JP51043763A patent/JPS51136688A/ja active Granted
- 1976-04-20 DE DE2617205A patent/DE2617205C3/de not_active Expired
- 1976-04-20 SU SU762346054A patent/SU638260A3/ru active
- 1976-04-20 AR AR262930A patent/AR210349A1/es active
- 1976-04-20 AT AT288376A patent/AT353795B/de not_active IP Right Cessation
- 1976-04-20 CH CH492676A patent/CH619462A5/de not_active IP Right Cessation
- 1976-04-20 PL PL1976188912A patent/PL99664B1/pl unknown
- 1976-04-20 LU LU74795A patent/LU74795A1/xx unknown
- 1976-04-20 BE BE166282A patent/BE840904A/xx not_active IP Right Cessation
- 1976-04-20 ZA ZA762320A patent/ZA762320B/xx unknown
- 1976-04-20 RO RO7685688A patent/RO73278A/ro unknown
- 1976-04-20 YU YU01006/76A patent/YU100676A/xx unknown
- 1976-04-20 BG BG032968A patent/BG34185A3/xx unknown
- 1976-04-21 PT PT65027A patent/PT65027B/pt unknown
- 1976-04-21 HU HU76ME00001967A patent/HU172684B/hu unknown
- 1976-04-21 IE IE828/76A patent/IE42979B1/en unknown
-
1977
- 1977-06-01 ES ES459405A patent/ES459405A1/es not_active Expired
- 1977-06-01 ES ES459406A patent/ES459406A1/es not_active Expired
- 1977-06-01 ES ES459407A patent/ES459407A1/es not_active Expired
-
1980
- 1980-10-02 KE KE3088A patent/KE3088A/xx unknown
- 1980-10-30 HK HK603/80A patent/HK60380A/xx unknown
-
1981
- 1981-12-30 MY MY225/81A patent/MY8100225A/xx unknown
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