NO132449B - - Google Patents
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- Publication number
- NO132449B NO132449B NO4826/71A NO482671A NO132449B NO 132449 B NO132449 B NO 132449B NO 4826/71 A NO4826/71 A NO 4826/71A NO 482671 A NO482671 A NO 482671A NO 132449 B NO132449 B NO 132449B
- Authority
- NO
- Norway
- Prior art keywords
- kanamycin
- solution
- neomycin
- sodium
- dihydrostreptomycin
- Prior art date
Links
- 239000000047 product Substances 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 26
- 229930193140 Neomycin Natural products 0.000 claims description 23
- 229960004927 neomycin Drugs 0.000 claims description 23
- 231100000419 toxicity Toxicity 0.000 claims description 23
- 230000001988 toxicity Effects 0.000 claims description 23
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 claims description 22
- 125000003277 amino group Chemical group 0.000 claims description 20
- 230000003115 biocidal effect Effects 0.000 claims description 20
- 229960000318 kanamycin Drugs 0.000 claims description 20
- 239000002253 acid Substances 0.000 claims description 19
- 239000003242 anti bacterial agent Substances 0.000 claims description 19
- 229930027917 kanamycin Natural products 0.000 claims description 19
- 229930182823 kanamycin A Natural products 0.000 claims description 19
- 229940088710 antibiotic agent Drugs 0.000 claims description 18
- PGBHMTALBVVCIT-VCIWKGPPSA-N framycetin Chemical compound N[C@@H]1[C@@H](O)[C@H](O)[C@H](CN)O[C@@H]1O[C@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](N)C[C@@H](N)[C@@H]2O)O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CN)O2)N)O[C@@H]1CO PGBHMTALBVVCIT-VCIWKGPPSA-N 0.000 claims description 17
- 150000003839 salts Chemical class 0.000 claims description 16
- 239000000126 substance Substances 0.000 claims description 15
- ASXBYYWOLISCLQ-UHFFFAOYSA-N Dihydrostreptomycin Natural products O1C(CO)C(O)C(O)C(NC)C1OC1C(CO)(O)C(C)OC1OC1C(N=C(N)N)C(O)C(N=C(N)N)C(O)C1O ASXBYYWOLISCLQ-UHFFFAOYSA-N 0.000 claims description 14
- 229960002222 dihydrostreptomycin Drugs 0.000 claims description 14
- ASXBYYWOLISCLQ-HZYVHMACSA-N dihydrostreptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](CO)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O ASXBYYWOLISCLQ-HZYVHMACSA-N 0.000 claims description 14
- 238000006243 chemical reaction Methods 0.000 claims description 9
- 239000007859 condensation product Substances 0.000 claims description 8
- 238000011065 in-situ storage Methods 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 7
- 229910052751 metal Chemical group 0.000 claims description 7
- 239000002184 metal Chemical group 0.000 claims description 7
- 229960003704 framycetin Drugs 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 5
- 238000004108 freeze drying Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 238000001556 precipitation Methods 0.000 claims description 3
- 239000003456 ion exchange resin Substances 0.000 claims description 2
- 229920003303 ion-exchange polymer Polymers 0.000 claims description 2
- 239000007858 starting material Substances 0.000 claims description 2
- 239000000243 solution Substances 0.000 description 53
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 42
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 25
- 239000011734 sodium Substances 0.000 description 24
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 23
- 229910052708 sodium Inorganic materials 0.000 description 23
- 239000000203 mixture Substances 0.000 description 18
- OOYGSFOGFJDDHP-KMCOLRRFSA-N kanamycin A sulfate Chemical compound OS(O)(=O)=O.O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N OOYGSFOGFJDDHP-KMCOLRRFSA-N 0.000 description 17
- 241001465754 Metazoa Species 0.000 description 15
- CZWJCQXZZJHHRH-YCRXJPFRSA-N 2-[(1r,2r,3s,4r,5r,6s)-3-(diaminomethylideneamino)-4-[(2r,3r,4r,5s)-3-[(2s,3s,4s,5r,6s)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine;sulfuric acid Chemical compound OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](CO)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](N=C(N)N)[C@H](O)[C@@H](N=C(N)N)[C@H](O)[C@H]1O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](CO)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](N=C(N)N)[C@H](O)[C@@H](N=C(N)N)[C@H](O)[C@H]1O CZWJCQXZZJHHRH-YCRXJPFRSA-N 0.000 description 10
- AYJRCSIUFZENHW-UHFFFAOYSA-L barium carbonate Chemical compound [Ba+2].[O-]C([O-])=O AYJRCSIUFZENHW-UHFFFAOYSA-L 0.000 description 10
- 244000005700 microbiome Species 0.000 description 10
- 229940053050 neomycin sulfate Drugs 0.000 description 10
- 229960001162 dihydrostreptomycin sulfate Drugs 0.000 description 9
- 239000002244 precipitate Substances 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 8
- 239000012153 distilled water Substances 0.000 description 8
- 238000001035 drying Methods 0.000 description 8
- 241000700159 Rattus Species 0.000 description 7
- 231100000636 lethal dose Toxicity 0.000 description 7
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
- 241000699670 Mus sp. Species 0.000 description 6
- 150000007513 acids Chemical class 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 6
- 230000006378 damage Effects 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 6
- 229960004279 formaldehyde Drugs 0.000 description 6
- 235000019256 formaldehyde Nutrition 0.000 description 6
- 229960002064 kanamycin sulfate Drugs 0.000 description 6
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 5
- 238000010521 absorption reaction Methods 0.000 description 5
- 238000002329 infrared spectrum Methods 0.000 description 5
- VYGBQXDNOUHIBZ-UHFFFAOYSA-L sodium formaldehyde sulphoxylate Chemical compound [Na+].[Na+].O=C.[O-]S[O-] VYGBQXDNOUHIBZ-UHFFFAOYSA-L 0.000 description 5
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 5
- 239000004289 sodium hydrogen sulphite Substances 0.000 description 5
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 4
- 238000010171 animal model Methods 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 4
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 235000015097 nutrients Nutrition 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 4
- LYPGDCWPTHTUDO-UHFFFAOYSA-M sodium;methanesulfinate Chemical compound [Na+].CS([O-])=O LYPGDCWPTHTUDO-UHFFFAOYSA-M 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- HRKQOINLCJTGBK-UHFFFAOYSA-N dihydroxidosulfur Chemical class OSO HRKQOINLCJTGBK-UHFFFAOYSA-N 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 201000008383 nephritis Diseases 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000011541 reaction mixture Substances 0.000 description 3
- 229920005989 resin Polymers 0.000 description 3
- 239000011347 resin Substances 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 229910021653 sulphate ion Inorganic materials 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- FPMIFORYYTWHJB-UHFFFAOYSA-N S1OCO1.[Na] Chemical compound S1OCO1.[Na] FPMIFORYYTWHJB-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- ITHZDDVSAWDQPZ-UHFFFAOYSA-L barium acetate Chemical compound [Ba+2].CC([O-])=O.CC([O-])=O ITHZDDVSAWDQPZ-UHFFFAOYSA-L 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000007665 chronic toxicity Effects 0.000 description 2
- 231100000160 chronic toxicity Toxicity 0.000 description 2
- 238000009833 condensation Methods 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 238000006482 condensation reaction Methods 0.000 description 2
- 230000010339 dilation Effects 0.000 description 2
- 230000009931 harmful effect Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000002427 irreversible effect Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- XWGJFPHUCFXLBL-UHFFFAOYSA-M rongalite Chemical compound [Na+].OCS([O-])=O XWGJFPHUCFXLBL-UHFFFAOYSA-M 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 235000010265 sodium sulphite Nutrition 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 239000008223 sterile water Substances 0.000 description 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
- 150000003871 sulfonates Chemical class 0.000 description 2
- 229960005486 vaccine Drugs 0.000 description 2
- OFNXOACBUMGOPC-HZYVHMACSA-N 5'-hydroxystreptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](CO)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O OFNXOACBUMGOPC-HZYVHMACSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 206010023435 Kidney small Diseases 0.000 description 1
- 241000588747 Klebsiella pneumoniae Species 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 206010029155 Nephropathy toxic Diseases 0.000 description 1
- DOZCGCLMCJKNKB-UHFFFAOYSA-N S(=O)(=O)(O)O.CS(=O)(=O)O.CS(=O)(=O)O Chemical compound S(=O)(=O)(O)O.CS(=O)(=O)O.CS(=O)(=O)O DOZCGCLMCJKNKB-UHFFFAOYSA-N 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 238000006640 acetylation reaction Methods 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229910052601 baryte Inorganic materials 0.000 description 1
- 239000010428 baryte Substances 0.000 description 1
- 238000006480 benzoylation reaction Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 229920001429 chelating resin Polymers 0.000 description 1
- 238000007385 chemical modification Methods 0.000 description 1
- RNFNDJAIBTYOQL-UHFFFAOYSA-N chloral hydrate Chemical compound OC(O)C(Cl)(Cl)Cl RNFNDJAIBTYOQL-UHFFFAOYSA-N 0.000 description 1
- 229960002327 chloral hydrate Drugs 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 210000003792 cranial nerve Anatomy 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- ISXSFOPKZQZDAO-UHFFFAOYSA-N formaldehyde;sodium Chemical compound [Na].O=C ISXSFOPKZQZDAO-UHFFFAOYSA-N 0.000 description 1
- QJQZEJFUIOWFMS-UHFFFAOYSA-N formaldehyde;sulfanediol Chemical class O=C.OSO QJQZEJFUIOWFMS-UHFFFAOYSA-N 0.000 description 1
- 230000001434 glomerular Effects 0.000 description 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 1
- 231100000086 high toxicity Toxicity 0.000 description 1
- DOUHZFSGSXMPIE-UHFFFAOYSA-N hydroxidooxidosulfur(.) Chemical compound [O]SO DOUHZFSGSXMPIE-UHFFFAOYSA-N 0.000 description 1
- OFNXOACBUMGOPC-UHFFFAOYSA-N hydroxystreptomycin Natural products CNC1C(O)C(O)C(CO)OC1OC1C(C=O)(O)C(CO)OC1OC1C(N=C(N)N)C(O)C(N=C(N)N)C(O)C1O OFNXOACBUMGOPC-UHFFFAOYSA-N 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 231100001231 less toxic Toxicity 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000011866 long-term treatment Methods 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- OIXVKQDWLFHVGR-WQDIDPJDSA-N neomycin B sulfate Chemical compound OS(O)(=O)=O.N[C@@H]1[C@@H](O)[C@H](O)[C@H](CN)O[C@@H]1O[C@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](N)C[C@@H](N)[C@@H]2O)O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CN)O2)N)O[C@@H]1CO OIXVKQDWLFHVGR-WQDIDPJDSA-N 0.000 description 1
- 230000007694 nephrotoxicity Effects 0.000 description 1
- 231100000417 nephrotoxicity Toxicity 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000002784 sclerotic effect Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 230000009528 severe injury Effects 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- XUIVKWAWICCWIQ-UHFFFAOYSA-M sodium;formaldehyde;hydrogen sulfite Chemical compound [Na+].O=C.OS([O-])=O XUIVKWAWICCWIQ-UHFFFAOYSA-M 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01B—CABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES
- H01B7/00—Insulated conductors or cables characterised by their form
- H01B7/17—Protection against damage caused by external factors, e.g. sheaths or armouring
- H01B7/28—Protection against damage caused by moisture, corrosion, chemical attack or weather
- H01B7/282—Preventing penetration of fluid, e.g. water or humidity, into conductor or cable
- H01B7/285—Preventing penetration of fluid, e.g. water or humidity, into conductor or cable by completely or partially filling interstices in the cable
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L91/00—Compositions of oils, fats or waxes; Compositions of derivatives thereof
- C08L91/06—Waxes
- C08L91/08—Mineral waxes
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01B—CABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES
- H01B3/00—Insulators or insulating bodies characterised by the insulating materials; Selection of materials for their insulating or dielectric properties
- H01B3/18—Insulators or insulating bodies characterised by the insulating materials; Selection of materials for their insulating or dielectric properties mainly consisting of organic substances
- H01B3/30—Insulators or insulating bodies characterised by the insulating materials; Selection of materials for their insulating or dielectric properties mainly consisting of organic substances plastics; resins; waxes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A30/00—Adapting or protecting infrastructure or their operation
- Y02A30/14—Extreme weather resilient electric power supply systems, e.g. strengthening power lines or underground power cables
Landscapes
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Organic Insulating Materials (AREA)
- Saccharide Compounds (AREA)
- Insulated Conductors (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO1127/73A NO134503C (cg-RX-API-DMAC10.html) | 1971-01-07 | 1973-03-20 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10459471A | 1971-01-07 | 1971-01-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO132449B true NO132449B (cg-RX-API-DMAC10.html) | 1975-08-04 |
| NO132449C NO132449C (cg-RX-API-DMAC10.html) | 1975-11-12 |
Family
ID=22301304
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO4826/71A NO132449C (cg-RX-API-DMAC10.html) | 1971-01-07 | 1971-12-23 | |
| NO1127/73A NO134503C (cg-RX-API-DMAC10.html) | 1971-01-07 | 1973-03-20 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO1127/73A NO134503C (cg-RX-API-DMAC10.html) | 1971-01-07 | 1973-03-20 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US3683104A (cg-RX-API-DMAC10.html) |
| JP (1) | JPS4713606A (cg-RX-API-DMAC10.html) |
| AU (1) | AU458524B2 (cg-RX-API-DMAC10.html) |
| BE (1) | BE777758A (cg-RX-API-DMAC10.html) |
| BR (1) | BR7200074D0 (cg-RX-API-DMAC10.html) |
| CA (1) | CA985441A (cg-RX-API-DMAC10.html) |
| DE (1) | DE2200306B2 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2120870A5 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1366223A (cg-RX-API-DMAC10.html) |
| IL (1) | IL38404A (cg-RX-API-DMAC10.html) |
| IT (1) | IT948112B (cg-RX-API-DMAC10.html) |
| NL (1) | NL7200259A (cg-RX-API-DMAC10.html) |
| NO (2) | NO132449C (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA718454B (cg-RX-API-DMAC10.html) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3830953A (en) * | 1970-02-16 | 1974-08-20 | Inmont Corp | Cable sealant |
| US3996413A (en) * | 1972-10-19 | 1976-12-07 | International Standard Electric Corporation | Sheathed stranded cable completely filled with water blocking composition |
| CA982804A (en) * | 1972-12-29 | 1976-02-03 | Shirley M. Beach | Composition for filling cables |
| US4110137A (en) * | 1972-12-29 | 1978-08-29 | Phillips Cable Limited | Composition for filling cables |
| US3875323A (en) * | 1973-10-01 | 1975-04-01 | Gen Cable Corp | Waterproof telephone cables with pliable non-flowing filling compound |
| USRE30321E (en) * | 1974-01-11 | 1980-07-01 | N L Industries, Inc. | Mineral oil extended polyurethane system containing a coupling agent for decontaminating and sealing the interior spaces of an insulated electrical device |
| US4108928A (en) * | 1976-03-02 | 1978-08-22 | Hanson Industries Inc. | Method of producing a viscous flowable pressure-compensating fitting composition from hollow thermoplastic microblends with the use of high frequency heating and dispensing the composition into a sealable, flexible, protective enclosure means |
| US4176239A (en) * | 1976-09-30 | 1979-11-27 | N L Industries, Inc. | Insulated electrical cable containing an agent for decontaminating and sealing the interior space thereof |
| US4190570A (en) * | 1977-05-20 | 1980-02-26 | Witco Chemical Corporation | Cable filler |
| US4105619A (en) * | 1977-05-20 | 1978-08-08 | Witco Chemical Corporation | Cable filler |
| DE2728642B2 (de) * | 1977-06-24 | 1981-02-05 | Siemens Ag, 1000 Berlin Und 8000 Muenchen | Längswasserdichtes Lichtwellenleiterkabel |
| US4110554A (en) * | 1978-02-08 | 1978-08-29 | Custom Cable Company | Buoyant tether cable |
| US4168258A (en) * | 1978-02-15 | 1979-09-18 | N L Industries, Inc. | Grease compatible, mineral oil extended polyurethane |
| US4281210A (en) * | 1978-02-15 | 1981-07-28 | Nl Industries, Inc. | Electrical devices containing a grease compatible, mineral oil extended polyurethane |
| US4243754A (en) * | 1978-09-05 | 1981-01-06 | Hanson Industries Incorporated | Viscous, flowable, pressure-compensating fitting compositions |
| CA1079512A (en) | 1978-11-16 | 1980-06-17 | Basil V.E. Walton | Powdered telephone cable filling compound |
| US4231986A (en) * | 1979-04-06 | 1980-11-04 | Nl Industries, Inc. | Grease compatible mineral oil extended polyurethane |
| US4404720A (en) * | 1979-06-26 | 1983-09-20 | Western Electric Company, Inc. | Apparatus for forming a metallic tape into a tube having an overlapped seam |
| US4308662A (en) * | 1979-06-26 | 1982-01-05 | Western Electric Company, Inc. | Methods of and apparatus for forming a metallic tape into a tube having an overlapped seam |
| US4342500A (en) * | 1979-08-10 | 1982-08-03 | Siemens Aktiengesellschaft | High voltage stabile optical cable structures |
| US4333706A (en) * | 1979-12-26 | 1982-06-08 | Siecor Corporation | Filling materials for communications cable |
| US4382821A (en) * | 1980-05-02 | 1983-05-10 | Siecor Corporation | Filling materials for communications cable |
| EP0039867B1 (de) * | 1980-05-12 | 1984-08-22 | Siemens Aktiengesellschaft | Längswasserdichtes Kabel, insbesondere Nachrichtenkabel |
| US4324453A (en) * | 1981-02-19 | 1982-04-13 | Siecor Corporation | Filling materials for electrical and light waveguide communications cables |
| US4426230A (en) | 1981-11-02 | 1984-01-17 | Siecor Corporation | Filling materials for communications cable |
| US4490577A (en) * | 1983-04-14 | 1984-12-25 | Harvey Hubbell Incorporated | Electrical cable for use in extreme environments |
| US4552907A (en) * | 1983-07-29 | 1985-11-12 | Kabushiki Kaisha Toyota Chuo Kenkyusho | Epoxy resin composition |
| US4641111A (en) * | 1983-11-14 | 1987-02-03 | Sage Laboratories, Inc. | Microwave coupler |
| US4547753A (en) * | 1983-11-14 | 1985-10-15 | Sage Laboratories, Inc. | Microwave coupler |
| JPH0722067B2 (ja) * | 1984-01-09 | 1995-03-08 | 日本石油化学株式会社 | コンデンサー |
| DE3404488A1 (de) * | 1984-02-06 | 1985-08-08 | Siemens AG, 1000 Berlin und 8000 München | Verfahren und fuellsubstanz zum herstellen eines laengswasserdichten kabels |
| US4707569A (en) * | 1985-06-03 | 1987-11-17 | Japan Styrene Paper Corporation | Multi-conductor cable |
| US4771079A (en) * | 1985-07-18 | 1988-09-13 | Melber George E | Graphic art printing media using a syntactic foam based on expanded hollow polymeric microspheres |
| US5461195A (en) * | 1986-03-26 | 1995-10-24 | Waterguard Industries, Inc. | Filled telecommunications cable having temperature stable mutual capacitance |
| HU210907B (en) * | 1989-04-07 | 1995-09-28 | Waterguard Ind | Jelly product for protecting enclosed places against water, and communication cables containing said jelly product |
| JPH03238410A (ja) * | 1990-02-16 | 1991-10-24 | Sumitomo Electric Ind Ltd | 通信用線材 |
| GB9304151D0 (en) * | 1993-03-02 | 1993-04-21 | Courtaulds Plc | Fibre |
| US5410901A (en) * | 1993-08-06 | 1995-05-02 | Sumitomo Electric Lightwave Corp. | Method and apparatus for forming overlapped tape |
| US20010009198A1 (en) | 1998-03-04 | 2001-07-26 | Sergio Belli | Electrical cable with self-repairing protection |
| US8101862B2 (en) * | 1999-01-11 | 2012-01-24 | Southwire Company | Self-sealing electrical cable using rubber resins |
| US6184473B1 (en) * | 1999-01-11 | 2001-02-06 | Southwire Company | Electrical cable having a self-sealing agent and method for preventing water from contacting the conductor |
| US6914193B2 (en) * | 1999-01-11 | 2005-07-05 | Southwire Company | Self-sealing electrical cable having a finned or ribbed structure between protective layers |
| US6359231B2 (en) * | 1999-01-11 | 2002-03-19 | Southwire Company, A Delaware Corporation | Electrical cable having a self-sealing agent and method for preventing water from contacting the conductor |
| US8470108B2 (en) | 1999-01-11 | 2013-06-25 | Southwire Company | Self-sealing electrical cable using rubber resins |
| US6463199B1 (en) | 1999-05-28 | 2002-10-08 | Corning Cable Systems Llc | Fiber optic cables with at least one water blocking zone |
| US7006740B1 (en) | 1999-05-28 | 2006-02-28 | Corning Cable Systems, Llc | Communication cable having a soft housing |
| US6748146B2 (en) | 1999-05-28 | 2004-06-08 | Corning Cable Systems Llc | Communication cable having a soft housing |
| US6374023B1 (en) | 1999-05-28 | 2002-04-16 | Corning Cable Systems Llc | Communication cable containing novel filling material in buffer tube |
| ATE344969T1 (de) * | 1999-12-20 | 2006-11-15 | Prysmian Cavi Sistemi Energia | Wasserdichtes elektrisches kabel |
| US7367373B2 (en) | 2000-12-06 | 2008-05-06 | Southwire Company | Multi-layer extrusion head for self-sealing cable |
| DE10218398B4 (de) * | 2001-04-25 | 2006-08-17 | Yazaki Corp. | Verfahren zur Herstellung einer Abzweigverbindung an einem abgeschirmten Leiter |
| US7247796B2 (en) | 2003-10-28 | 2007-07-24 | 3M Innovative Properties Company | Filling materials |
| US20060247359A1 (en) * | 2005-04-28 | 2006-11-02 | 3M Innovative Properties Company | Sealant materials and methods of using thereof |
| US7902288B2 (en) * | 2005-05-31 | 2011-03-08 | 3M Innovative Properties Company | Sealant materials containing diblock copolymers and methods of making thereof |
| DE102006042369A1 (de) * | 2006-09-08 | 2008-03-27 | Robert Bosch Gmbh | Vorrichtung und Verfahren zur Längsabdichtung von elektrischen Leitungen |
| US8089000B2 (en) * | 2007-10-12 | 2012-01-03 | General Cable Technologies Corporation | Waterproof data cable with foam filler and water blocking material |
| EP2078971A1 (en) * | 2007-12-20 | 2009-07-15 | ABB Research Ltd. | A cable, a method of producing such a cable, and use thereof |
| US7750243B1 (en) * | 2009-03-10 | 2010-07-06 | Superior Essex Communications Lp | Water blocked communication cable comprising filling compound and method of fabrication |
| US20120073859A1 (en) * | 2010-09-24 | 2012-03-29 | Freescale Semiconductor, Inc | Polymer core wire |
| USD679253S1 (en) * | 2011-02-11 | 2013-04-02 | Jinwei Wire & Cable Co. | Electric wire |
| USD745851S1 (en) * | 2013-07-10 | 2015-12-22 | Paracable, Inc. | Electronics cable |
| USD740760S1 (en) * | 2014-08-06 | 2015-10-13 | Michael Gene Gliksman | Braided electrical speaker cable |
| DE102017210096B4 (de) * | 2017-06-16 | 2024-02-08 | Bizlink Industry Germany Gmbh | Datenkabel für explosionsgefährdete Bereiche |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB698055A (en) * | 1951-03-21 | 1953-10-07 | British Insulated Callenders | Improvements in the manufacture of electric cables |
| GB995582A (en) * | 1963-05-21 | 1965-06-16 | British Insulated Callenders | Improvements in or relating to telecommunication cables |
| BE758373A (fr) * | 1967-11-27 | 1971-05-03 | Dow Chemical Co | Procede de fabrication de papier |
-
1971
- 1971-01-07 US US104594A patent/US3683104A/en not_active Expired - Lifetime
- 1971-12-13 CA CA130,023A patent/CA985441A/en not_active Expired
- 1971-12-17 AU AU37059/71A patent/AU458524B2/en not_active Expired
- 1971-12-17 ZA ZA718454A patent/ZA718454B/xx unknown
- 1971-12-20 IL IL38404A patent/IL38404A/xx unknown
- 1971-12-23 NO NO4826/71A patent/NO132449C/no unknown
- 1971-12-24 FR FR7146603A patent/FR2120870A5/fr not_active Expired
-
1972
- 1972-01-04 GB GB31472A patent/GB1366223A/en not_active Expired
- 1972-01-05 DE DE19722200306 patent/DE2200306B2/de not_active Withdrawn
- 1972-01-05 IT IT47576/72A patent/IT948112B/it active
- 1972-01-06 BE BE777758A patent/BE777758A/xx unknown
- 1972-01-06 BR BR000074/72A patent/BR7200074D0/pt unknown
- 1972-01-07 JP JP442872A patent/JPS4713606A/ja active Pending
- 1972-01-07 NL NL7200259A patent/NL7200259A/xx unknown
- 1972-05-15 US US00253096A patent/US3843568A/en not_active Expired - Lifetime
-
1973
- 1973-03-20 NO NO1127/73A patent/NO134503C/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2200306A1 (de) | 1972-07-27 |
| IL38404A0 (en) | 1972-02-29 |
| IL38404A (en) | 1974-06-30 |
| NL7200259A (cg-RX-API-DMAC10.html) | 1972-07-11 |
| DE2200306B2 (de) | 1976-05-26 |
| BE777758A (fr) | 1972-07-06 |
| AU458524B2 (en) | 1975-02-27 |
| ZA718454B (en) | 1972-09-27 |
| BR7200074D0 (pt) | 1973-08-23 |
| GB1366223A (en) | 1974-09-11 |
| NO134503C (cg-RX-API-DMAC10.html) | 1976-10-20 |
| US3843568A (en) | 1974-10-22 |
| FR2120870A5 (cg-RX-API-DMAC10.html) | 1972-08-18 |
| NO134503B (cg-RX-API-DMAC10.html) | 1976-07-12 |
| NO132449C (cg-RX-API-DMAC10.html) | 1975-11-12 |
| CA985441A (en) | 1976-03-09 |
| AU3705971A (en) | 1973-06-21 |
| IT948112B (it) | 1973-05-30 |
| JPS4713606A (cg-RX-API-DMAC10.html) | 1972-07-17 |
| US3683104A (en) | 1972-08-08 |
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