NL9020159A - Transdermaal geneesmiddelafgeefsysteem met een acryl bevattend multipolymeer. - Google Patents
Transdermaal geneesmiddelafgeefsysteem met een acryl bevattend multipolymeer. Download PDFInfo
- Publication number
- NL9020159A NL9020159A NL9020159A NL9020159A NL9020159A NL 9020159 A NL9020159 A NL 9020159A NL 9020159 A NL9020159 A NL 9020159A NL 9020159 A NL9020159 A NL 9020159A NL 9020159 A NL9020159 A NL 9020159A
- Authority
- NL
- Netherlands
- Prior art keywords
- drug
- vinyl acetate
- rubber
- adhesive
- ethylene
- Prior art date
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- 239000003814 drug Substances 0.000 claims abstract description 138
- 229940079593 drug Drugs 0.000 claims abstract description 107
- 239000000203 mixture Substances 0.000 claims abstract description 89
- 230000001070 adhesive effect Effects 0.000 claims abstract description 80
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- 239000000853 adhesive Substances 0.000 claims abstract description 78
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- 229920000058 polyacrylate Polymers 0.000 claims abstract description 28
- 230000002500 effect on skin Effects 0.000 claims abstract description 27
- 239000000178 monomer Substances 0.000 claims abstract description 13
- 229920003051 synthetic elastomer Polymers 0.000 claims abstract description 9
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- 229920001194 natural rubber Polymers 0.000 claims abstract description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 45
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims description 36
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims description 35
- 229960005309 estradiol Drugs 0.000 claims description 35
- 229930182833 estradiol Natural products 0.000 claims description 34
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- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical group [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 claims description 19
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- 239000000006 Nitroglycerin Substances 0.000 claims description 18
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- 229920001897 terpolymer Polymers 0.000 claims description 12
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 6
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- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 abstract description 32
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/58—Adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/58—Adhesives
- A61L15/585—Mixtures of macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26F—PERFORATING; PUNCHING; CUTTING-OUT; STAMPING-OUT; SEVERING BY MEANS OTHER THAN CUTTING
- B26F1/00—Perforating; Punching; Cutting-out; Stamping-out; Apparatus therefor
- B26F1/38—Cutting-out; Stamping-out
- B26F1/44—Cutters therefor; Dies therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26F—PERFORATING; PUNCHING; CUTTING-OUT; STAMPING-OUT; SEVERING BY MEANS OTHER THAN CUTTING
- B26F1/00—Perforating; Punching; Cutting-out; Stamping-out; Apparatus therefor
- B26F1/38—Cutting-out; Stamping-out
- B26F1/384—Cutting-out; Stamping-out using rotating drums
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Manufacturing & Machinery (AREA)
- Botany (AREA)
- Forests & Forestry (AREA)
- Mechanical Engineering (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Discharge Of Articles From Conveyors (AREA)
- Sorting Of Articles (AREA)
- Combined Means For Separation Of Solids (AREA)
- Materials For Medical Uses (AREA)
- Adhesives Or Adhesive Processes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29584789 | 1989-01-11 | ||
| US07/295,847 US4994267A (en) | 1988-03-04 | 1989-01-11 | Transdermal acrylic multipolymer drug delivery system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL9020159A true NL9020159A (nl) | 1991-01-02 |
Family
ID=23139462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL9020159A NL9020159A (nl) | 1989-01-11 | 1990-01-10 | Transdermaal geneesmiddelafgeefsysteem met een acryl bevattend multipolymeer. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4994267A (da) |
| EP (3) | EP0634179A1 (da) |
| JP (1) | JPH0793939B2 (da) |
| KR (1) | KR920703220A (da) |
| AT (1) | ATE122240T1 (da) |
| CA (1) | CA2044132C (da) |
| DE (1) | DE69019175T2 (da) |
| DK (1) | DK0379045T3 (da) |
| ES (1) | ES2071683T3 (da) |
| HK (1) | HK1006155A1 (da) |
| IE (1) | IE69048B1 (da) |
| NL (1) | NL9020159A (da) |
| PT (1) | PT92830B (da) |
| WO (1) | WO1990007940A1 (da) |
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-
1989
- 1989-01-11 US US07/295,847 patent/US4994267A/en not_active Expired - Lifetime
-
1990
- 1990-01-10 CA CA002044132A patent/CA2044132C/en not_active Expired - Lifetime
- 1990-01-10 NL NL9020159A patent/NL9020159A/nl not_active Application Discontinuation
- 1990-01-10 DE DE69019175T patent/DE69019175T2/de not_active Expired - Lifetime
- 1990-01-10 AT AT90100430T patent/ATE122240T1/de not_active IP Right Cessation
- 1990-01-10 EP EP94113992A patent/EP0634179A1/en not_active Withdrawn
- 1990-01-10 IE IE9090A patent/IE69048B1/en not_active IP Right Cessation
- 1990-01-10 JP JP2502850A patent/JPH0793939B2/ja not_active Expired - Lifetime
- 1990-01-10 ES ES90100430T patent/ES2071683T3/es not_active Expired - Lifetime
- 1990-01-10 EP EP90100430A patent/EP0379045B1/en not_active Expired - Lifetime
- 1990-01-10 WO PCT/US1990/000242 patent/WO1990007940A1/en not_active Application Discontinuation
- 1990-01-10 EP EP90902716A patent/EP0453505A1/en active Pending
- 1990-01-10 DK DK90100430.9T patent/DK0379045T3/da active
- 1990-01-10 PT PT92830A patent/PT92830B/pt not_active IP Right Cessation
- 1990-11-14 KR KR1019920701652A patent/KR920703220A/ko not_active Application Discontinuation
-
1998
- 1998-06-12 HK HK98105244A patent/HK1006155A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69019175T2 (de) | 1996-01-18 |
| EP0379045A1 (en) | 1990-07-25 |
| DK0379045T3 (da) | 1995-10-09 |
| AU5034990A (en) | 1990-08-13 |
| KR920703220A (ko) | 1992-12-17 |
| CA2044132A1 (en) | 1990-07-12 |
| IE900090L (en) | 1990-07-11 |
| ES2071683T3 (es) | 1995-07-01 |
| US4994267A (en) | 1991-02-19 |
| JPH0793939B2 (ja) | 1995-10-11 |
| DE69019175D1 (de) | 1995-06-14 |
| ATE122240T1 (de) | 1995-05-15 |
| IE69048B1 (en) | 1996-08-07 |
| PT92830B (pt) | 1995-12-29 |
| JPH04502719A (ja) | 1992-05-21 |
| HK1006155A1 (en) | 1999-02-12 |
| EP0634179A1 (en) | 1995-01-18 |
| CA2044132C (en) | 1997-05-06 |
| PT92830A (pt) | 1990-07-31 |
| EP0379045B1 (en) | 1995-05-10 |
| WO1990007940A1 (en) | 1990-07-26 |
| AU632534B2 (en) | 1993-01-07 |
| EP0453505A1 (en) | 1991-10-30 |
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| BV | The patent application has lapsed |