NL8900943A - Protease inhibitor. - Google Patents

Protease inhibitor. Download PDF

Info

Publication number
NL8900943A
NL8900943A NL8900943A NL8900943A NL8900943A NL 8900943 A NL8900943 A NL 8900943A NL 8900943 A NL8900943 A NL 8900943A NL 8900943 A NL8900943 A NL 8900943A NL 8900943 A NL8900943 A NL 8900943A
Authority
NL
Netherlands
Prior art keywords
protease
substance according
gelin
inhibitor
chymotrypsin
Prior art date
Application number
NL8900943A
Other languages
English (en)
Dutch (nl)
Original Assignee
Euro Biopharm Technology B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Biopharm Technology B V filed Critical Euro Biopharm Technology B V
Priority to NL8900943A priority Critical patent/NL8900943A/nl
Priority to CA002053242A priority patent/CA2053242C/en
Priority to JP02506704A priority patent/JP3101629B2/ja
Priority to DE69031424T priority patent/DE69031424T2/de
Priority to ES90907508T priority patent/ES2108694T3/es
Priority to DK90907508.7T priority patent/DK0466833T3/da
Priority to PCT/NL1990/000046 priority patent/WO1990012808A1/en
Priority to KR1019910701325A priority patent/KR0167344B1/ko
Priority to AU55492/90A priority patent/AU648252B2/en
Priority to US07/768,226 priority patent/US5397694A/en
Priority to AT90907508T priority patent/ATE157989T1/de
Priority to EP90907508A priority patent/EP0466833B1/en
Publication of NL8900943A publication Critical patent/NL8900943A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NL8900943A 1989-04-14 1989-04-14 Protease inhibitor. NL8900943A (nl)

Priority Applications (12)

Application Number Priority Date Filing Date Title
NL8900943A NL8900943A (nl) 1989-04-14 1989-04-14 Protease inhibitor.
CA002053242A CA2053242C (en) 1989-04-14 1990-04-12 Protease inhibitor
JP02506704A JP3101629B2 (ja) 1989-04-14 1990-04-12 プロテアーゼインヒビター
DE69031424T DE69031424T2 (de) 1989-04-14 1990-04-12 Proteasehemmer
ES90907508T ES2108694T3 (es) 1989-04-14 1990-04-12 Inhibidor de proteasa.
DK90907508.7T DK0466833T3 (da) 1989-04-14 1990-04-12 Insekticide og synergistiske miticide midler
PCT/NL1990/000046 WO1990012808A1 (en) 1989-04-14 1990-04-12 Protease inhibitor
KR1019910701325A KR0167344B1 (ko) 1989-04-14 1990-04-12 프로테아제 억제제
AU55492/90A AU648252B2 (en) 1989-04-14 1990-04-12 Protease inhibitor
US07/768,226 US5397694A (en) 1989-04-14 1990-04-12 Protease inhibitor
AT90907508T ATE157989T1 (de) 1989-04-14 1990-04-12 Proteasehemmer
EP90907508A EP0466833B1 (en) 1989-04-14 1990-04-12 Protease inhibitor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8900943 1989-04-14
NL8900943A NL8900943A (nl) 1989-04-14 1989-04-14 Protease inhibitor.

Publications (1)

Publication Number Publication Date
NL8900943A true NL8900943A (nl) 1990-11-01

Family

ID=19854482

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8900943A NL8900943A (nl) 1989-04-14 1989-04-14 Protease inhibitor.

Country Status (12)

Country Link
US (1) US5397694A (da)
EP (1) EP0466833B1 (da)
JP (1) JP3101629B2 (da)
KR (1) KR0167344B1 (da)
AT (1) ATE157989T1 (da)
AU (1) AU648252B2 (da)
CA (1) CA2053242C (da)
DE (1) DE69031424T2 (da)
DK (1) DK0466833T3 (da)
ES (1) ES2108694T3 (da)
NL (1) NL8900943A (da)
WO (1) WO1990012808A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0662514A1 (en) * 1994-01-07 1995-07-12 Ciba-Geigy Ag Hirustasin, an antistasin type serine proteinase inhibitor from Hiruda
NZ270194A (en) * 1994-01-07 1996-05-28 Ciba Geigy Ag Hirustasin, a serine protease inhibitor from hirudo medicinalis
KR0137519B1 (ko) * 1995-04-27 1998-04-30 심상철 한국산 흡혈종 거머리(Hirudo nipponia)로 부터 분리한 일래스테이즈 억제 단백질 및 그의 제조방법
GB2304048A (en) * 1995-08-12 1997-03-12 John William Carson Medicament containing saliva extract
KR100224383B1 (ko) 1996-09-09 1999-10-15 윤덕용 거머린에서 유도된 단백질분해효소 억제활성을지닌 펩타이드
FR2755015B1 (fr) * 1996-10-25 1998-12-24 Sod Conseils Rech Applic Utilisation d'un extrait flavonoidique de ginkgo biloba substantiellement depourvu de terpenes, dans le domaine buccodentaire, et composition contenant un tel extrait
FR2763944B1 (fr) * 1997-06-03 2000-12-15 Centre Nat Rech Scient Nouveaux derives de coumarines, leurs procedes de preparation et leur application comme medicaments en tant qu'inhibiteurs de proteases
AT406120B (de) * 1997-08-28 2000-02-25 Immuno Ag Gewebekleber
US7063838B1 (en) * 1999-09-24 2006-06-20 Proteon Therapeutics Llc Methods for treating an artery or vein in a human subject
AU7612100A (en) * 1999-09-24 2001-04-24 Johns Hopkins University, The Systems and methods for opening obstructed biological conduits
US7632494B2 (en) * 1999-09-24 2009-12-15 Proteon Therapeutics, Inc. Methods for enlarging the diameter of a biological conduit in a human subject
US20080025966A1 (en) * 2004-01-30 2008-01-31 Currie Mark G Methods And Compositions For The Treatment Of Gastrointestinal disorders
US7691839B2 (en) * 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
EP2316465A1 (en) * 2009-10-15 2011-05-04 Centre National De La Recherche Scientifique Use of extract of leeches' saliva as anti-bacterial agent for the manufacture of different compositons

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2808396C2 (de) * 1978-02-27 1984-04-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Protease-Inhibitoren
DE3445532A1 (de) * 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Hirudin-pa, desulfatohirudine-pa, verfahren zur herstellung und pharmazeutische mittel, die diese wirkstoffe enthalten

Also Published As

Publication number Publication date
DE69031424D1 (de) 1997-10-16
EP0466833A1 (en) 1992-01-22
WO1990012808A1 (en) 1990-11-01
DK0466833T3 (da) 1998-04-14
EP0466833B1 (en) 1997-09-10
AU5549290A (en) 1990-11-16
ES2108694T3 (es) 1998-01-01
JP3101629B2 (ja) 2000-10-23
ATE157989T1 (de) 1997-09-15
CA2053242C (en) 2000-09-19
KR920701247A (ko) 1992-08-11
KR0167344B1 (ko) 1999-01-15
CA2053242A1 (en) 1990-10-15
US5397694A (en) 1995-03-14
DE69031424T2 (de) 1998-04-09
JPH04507238A (ja) 1992-12-17
AU648252B2 (en) 1994-04-21

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BV The patent application has lapsed