NL8703088A - Werkwijze voor het vermenigvuldigen van runderembryo's en aldus verkregen embryo's. - Google Patents

Werkwijze voor het vermenigvuldigen van runderembryo's en aldus verkregen embryo's. Download PDF

Info

Publication number
NL8703088A
NL8703088A NL8703088A NL8703088A NL8703088A NL 8703088 A NL8703088 A NL 8703088A NL 8703088 A NL8703088 A NL 8703088A NL 8703088 A NL8703088 A NL 8703088A NL 8703088 A NL8703088 A NL 8703088A
Authority
NL
Netherlands
Prior art keywords
membrane
oocyte
embryo
recipient
bound
Prior art date
Application number
NL8703088A
Other languages
English (en)
Dutch (nl)
Original Assignee
First Neal L
Prather Randall S
Barnes Frank
Robl James M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by First Neal L, Prather Randall S, Barnes Frank, Robl James M filed Critical First Neal L
Publication of NL8703088A publication Critical patent/NL8703088A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NL8703088A 1986-12-31 1987-12-21 Werkwijze voor het vermenigvuldigen van runderembryo's en aldus verkregen embryo's. NL8703088A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US94826986A 1986-12-31 1986-12-31
US94826986 1986-12-31
US07/113,791 US4994384A (en) 1986-12-31 1987-10-27 Multiplying bovine embryos
US11379187 1987-10-27

Publications (1)

Publication Number Publication Date
NL8703088A true NL8703088A (nl) 1988-07-18

Family

ID=26811480

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8703088A NL8703088A (nl) 1986-12-31 1987-12-21 Werkwijze voor het vermenigvuldigen van runderembryo's en aldus verkregen embryo's.

Country Status (11)

Country Link
US (1) US4994384A (fr)
JP (1) JP2882527B2 (fr)
AU (1) AU623846B2 (fr)
CA (1) CA1338931C (fr)
CH (1) CH685765A5 (fr)
DE (1) DE3744113C2 (fr)
FR (1) FR2609045B1 (fr)
GB (1) GB2199845A (fr)
MX (1) MX166981B (fr)
NL (1) NL8703088A (fr)
NZ (1) NZ222740A (fr)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057420A (en) * 1987-06-05 1991-10-15 Granada Biosciences, Inc. Bovine nuclear transplantation
IL86588A0 (en) * 1987-06-05 1988-11-30 Granada Genetics Inc Bovine nuclear transplantation
US5633076A (en) * 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
US5453366A (en) * 1990-07-26 1995-09-26 Sims; Michele M. Method of cloning bovine embryos
US5096822A (en) * 1990-07-26 1992-03-17 W. R. Grace & Co.- Conn. Bovine embryo medium
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
PT620849E (pt) * 1992-01-07 2003-11-28 Elan Pharm Inc Modelos animais transgenicos para a doenca de alzheimer
NZ247062A (en) * 1992-03-04 1995-07-26 Grace W R & Co Method for bovine nuclear transfer
US6107543A (en) * 1992-08-20 2000-08-22 Infigen, Inc. Culture of totipotent embryonic inner cells mass cells and production of bovine animals
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5480772A (en) * 1993-02-03 1996-01-02 Brandeis University In vitro activation of a nucleus
US6680199B1 (en) 1993-02-10 2004-01-20 Infigen, Inc. In vitro activation of mammalian oocytes
US5496720A (en) * 1993-02-10 1996-03-05 Susko-Parrish; Joan L. Parthenogenic oocyte activation
US20030083733A1 (en) * 1997-10-10 2003-05-01 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US20020091433A1 (en) * 1995-04-19 2002-07-11 Ni Ding Drug release coated stent
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US6717031B2 (en) 1995-06-07 2004-04-06 Kate Dora Games Method for selecting a transgenic mouse model of alzheimer's disease
US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
US20010047520A1 (en) * 1996-03-04 2001-11-29 Susko-Parrish Joan L. Parthenogenic oocyte activation
US7696404B2 (en) * 1996-08-19 2010-04-13 Advanced Cell Technology, Inc. Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
US20090092588A1 (en) * 1997-01-10 2009-04-09 University Of Massachusetts As Represented By Its Amherst Campus Cloned ungulate embryos and animals, use of cells, tissues and organs thereof for transplantation therapies including parkinson's disease
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
US6215041B1 (en) * 1997-01-10 2001-04-10 University Of Mmassachusetts Cloning using donor nuclei from a non-quiesecent somatic cells
US6011197A (en) 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
US6331659B1 (en) 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
US6700037B2 (en) 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
US6258998B1 (en) 1998-11-24 2001-07-10 Infigen, Inc. Method of cloning porcine animals
SE9902817D0 (sv) * 1999-07-30 1999-07-30 A & Science Invest Ab A method for selective electrofusion of at least two fusion partners having cell-like membranes
US6383813B1 (en) 1999-09-14 2002-05-07 Cornell Research Foundation, Inc. Microfabrication of a nuclear transfer array for high-throughput animal cloning
WO2001035735A1 (fr) * 1999-11-19 2001-05-25 Hematech, Llc Production d'ongules, de preference des bovins, qui produisent des immunoglobulines humaines
US7820878B2 (en) * 1999-11-19 2010-10-26 Kyowa Hakko Kirin Co., Ltd. Production of ungulates, preferably bovines that produce human immunoglobulins
US7414170B2 (en) * 1999-11-19 2008-08-19 Kirin Beer Kabushiki Kaisha Transgenic bovines capable of human antibody production
US7074983B2 (en) 1999-11-19 2006-07-11 Kirin Beer Kabushiki Kaisha Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin
ATE517990T1 (de) 2000-03-15 2011-08-15 Univ Georgia Effektive kernumprogrammierung in säugetieren
EA013564B1 (ru) * 2000-08-03 2010-06-30 Терапеутик Хьюман Поликлоналз Инк. Гуманизированный иммуноглобулин и содержащая его фармацевтическая композиция
US6677500B2 (en) * 2000-08-15 2004-01-13 Board Of Trustees Of The University Of Illinois Ungulates expressing exogenous IGF-I in their milk
US20040029825A1 (en) * 2001-10-03 2004-02-12 Davies Christopher J Methods of minimizing immunological rejection of a nuclear transfer fetus
US20030027331A1 (en) * 2000-11-30 2003-02-06 Yan Wen Liang Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same
EP1356035B1 (fr) 2000-12-22 2011-03-16 Kyowa Hakko Kirin Co., Ltd. Methodes de clonage de mammiferes non humains a l'aide de chromatine donneuse reprogrammee ou de cellules donneuses reprogrammees
US7491534B2 (en) * 2000-12-22 2009-02-17 Kirin Holdings Kabushiki Kaisha Methods for altering cell fate to generate T-cells specific for an antigen of interest
US20020142397A1 (en) * 2000-12-22 2002-10-03 Philippe Collas Methods for altering cell fate
JP4223284B2 (ja) * 2001-01-02 2009-02-12 ステムロン インコーポレイテッド 予め選抜されたイムノタイプおよび／またはジェノタイプを有するホモ接合性幹細胞群の製造方法、該細胞由来の移植に適切な細胞、並びにこれらを用いた材料および方法
AUPR446701A0 (en) * 2001-04-18 2001-05-17 Gene Stream Pty Ltd Transgenic mammals for pharmacological and toxicological studies
US6613083B2 (en) * 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US20030113910A1 (en) * 2001-12-18 2003-06-19 Mike Levanduski Pluripotent stem cells derived without the use of embryos or fetal tissue
US20040133931A1 (en) * 2003-01-08 2004-07-08 Gavin William G. Method and system for fusion and activation following nuclear transfer in reconstructed embryos
US20030229909A1 (en) * 2002-02-13 2003-12-11 The Texas A&M University System Cloning cats by nuclear transplantation
EP1490487A4 (fr) * 2002-04-01 2007-08-29 Gtc Biotherapeutics Inc Procede permettant la selection de lignees cellulaires convenant pour le transfert de noyau chez les especes mammiferes
US7371922B2 (en) * 2002-07-31 2008-05-13 The Board Of Trustees Of The University Of Illinois Nuclear transfer with porcine embryonic stem cells
AU2003257155A1 (en) * 2002-08-02 2004-02-23 The General Hospital Corporation Methods for the production of cells and mammals with desired genetic modifications
EP1544286A4 (fr) * 2002-08-08 2007-06-27 Univ Tokyo Nat Univ Corp Robot pouvant mettre en oeuvre des operations sur une cellule unique
DE60330468D1 (de) 2002-08-21 2010-01-21 Revivicor Inc Schweine ohne jegliche expression funktioneller alpha-1,3-galactosyltransferase
US8106251B2 (en) 2002-08-21 2012-01-31 Revivicor, Inc. Tissue products derived from porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase
US20040077077A1 (en) * 2002-10-18 2004-04-22 Xiangzhong Yang Novel methods for the production of cloned mammals, mammals cloned according to the methods, and methods of use of same
KR20050093761A (ko) 2002-11-08 2005-09-23 헤마테크, 엘엘씨 프리온 단백질 활성이 감소된 트랜스제닉 유제동물 및 그의용도
WO2004053090A2 (fr) * 2002-12-10 2004-06-24 Gtc Biotherapeutics, Inc. Procede et systeme d'utilisation d'embryons de transfert nucleaire cellulaire de cellule somatique en tant que donneurs de cellules pour un transfert nucleaire supplementaire
WO2005037191A2 (fr) * 2003-09-15 2005-04-28 Gtc Biotherapeutics, Inc. Expression de recepteurs transmembranaires negatifs dominants dans le lait d'animaux transgeniques
NZ550106A (en) * 2004-04-22 2009-06-26 Kyowa Hakko Kirin Co Ltd Transgenic animals and uses thereof
NZ554824A (en) 2004-10-22 2010-10-29 Revivicor Inc Porcines that lack endogenous antibody chains and express exogenous immunoglobulins
KR100733012B1 (ko) 2005-07-26 2007-06-28 재단법인서울대학교산학협력재단 복제된 개과 동물 및 이의 생산 방법
ES2836764T3 (es) 2005-08-03 2021-06-28 Astellas Inst For Regenerative Medicine Métodos mejorados de reprogramación de células somáticas animales
EP1924686A4 (fr) 2005-08-09 2009-11-11 Revivicor Inc Ongules transgéniques exprimant la ctla4-ig et leurs utilisations
CN100357435C (zh) * 2006-01-13 2007-12-26 山东大学 一种细胞核移植的方法
JP5087625B2 (ja) 2006-09-01 2012-12-05 セラピューティック・ヒューマン・ポリクローナルズ・インコーポレーテッド 非ヒトトランスジェニック動物におけるヒトまたはヒト化免疫グロブリンの発現強化
KR100829426B1 (ko) * 2007-01-17 2008-05-15 재단법인서울대학교산학협력재단 복제개의 생산 방법
CA2679109C (fr) 2007-02-23 2016-07-19 Advanced Cell Technology, Inc. Derivation de cellules souches embryonnaires
KR100868245B1 (ko) * 2007-05-29 2008-11-11 강원대학교산학협력단 데메콜친 처리에 의한 효율적인 복제 동물의 생산방법
CN101668847A (zh) * 2007-11-19 2010-03-10 财团法人首尔大学校产学协力财团 用于体细胞核移植的犬科出生率的提高方法
JP2011508600A (ja) 2008-01-04 2011-03-17 ソウル ナショナル ユニバーシティ インダストリー ファウンデーション 形質転換された複製犬の生産方法
EP2348827B1 (fr) 2008-10-27 2015-07-01 Revivicor, Inc. Ongulés immunodéprimés
WO2012112586A1 (fr) 2011-02-14 2012-08-23 Revivicor, Inc. Cochons génétiquement modifiés destinés à la xénotransplantation de xénogreffes vascularisées et de dérivés de celles-ci
WO2015081182A1 (fr) 2013-11-27 2015-06-04 The Curators Of The University Of Missouri Activation artificielle d'oocyte
KR102617137B1 (ko) 2014-09-15 2023-12-27 칠드런'즈 메디컬 센터 코포레이션 히스톤 h3-리신 트리메틸화를 제거함으로써 체세포 핵 이식(scnt) 효율을 증가시키는 방법 및 조성물
CA3096274A1 (fr) 2018-04-06 2019-10-10 Children's Medical Center Corporation Compositions et procedes de reprogrammation de cellules somatiques et de modulation d'impression
EP4247151A1 (fr) 2020-11-20 2023-09-27 Revivicor Inc. Porcs multitransgéniques présentant une inactivation du récepteur de l'hormone de croissance pour une xénogreffe
CA3232376A1 (fr) 2021-09-20 2023-03-23 Maria KOKKINAKI Porcs sceniques multitran comprenant dix modifications genetiques pour une xenogreffe

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3906929A (en) * 1973-11-23 1975-09-23 Lynn Lawrence Augspurger Processes for reproduction of cellular bodies
US4664097A (en) * 1984-05-09 1987-05-12 The Wistar Institute Of Anatomy & Biology Nuclear transplantation in the mammalian embryo by microsurgery and cell fusion
IL86588A0 (en) * 1987-06-05 1988-11-30 Granada Genetics Inc Bovine nuclear transplantation

Also Published As

Publication number Publication date
CA1338931C (fr) 1997-02-25
CH685765A5 (de) 1995-09-29
JP2882527B2 (ja) 1999-04-12
AU623846B2 (en) 1992-05-28
AU8318887A (en) 1988-07-07
DE3744113A1 (de) 1988-07-14
DE3744113C2 (de) 1998-04-09
NZ222740A (en) 1990-12-21
MX166981B (es) 1993-02-18
FR2609045A1 (fr) 1988-07-01
FR2609045B1 (fr) 1993-09-17
GB2199845A (en) 1988-07-20
GB8729856D0 (en) 1988-02-03
JPS63291523A (ja) 1988-11-29
US4994384A (en) 1991-02-19

Similar Documents

Publication Publication Date Title
NL8703088A (nl) Werkwijze voor het vermenigvuldigen van runderembryo's en aldus verkregen embryo's.
Robl et al. Nuclear transplantation in bovine embryos
US5057420A (en) Bovine nuclear transplantation
US5453366A (en) Method of cloning bovine embryos
US20040177390A1 (en) Method of nuclear transfer
AU2005203115A1 (en) Double nuclear transfer method and results thereof
Eyestone et al. Nuclear transfer from somatic cells: applications in farm animal species
CA2396210A1 (fr) Procede de clonage d'animaux avec modifications genetiques ciblees, par transfert de noyaux cellulaires somatiques males ou femelles a culture a long terme, comprenant des modifications genetiques provoquees artificiellement, dans des cellules receveuses enuclees
EP0365562B1 (fr) Transplantation nucleaire bovine
EP0559307A1 (fr) Procédé de maturation des oocytes receveurs pour la multiplication des embryons bovins
US20030217378A1 (en) Cloning using rapidly matured oocytes
US7531715B1 (en) Double nuclear transfer method and results thereof
US20040077077A1 (en) Novel methods for the production of cloned mammals, mammals cloned according to the methods, and methods of use of same
JPH0614945A (ja) 豚の繁殖方法
AU2002248983B2 (en) A method of nuclear transfer
AU755743B2 (en) Porcine nuclear transfer
WO2001030970A2 (fr) Protocole ameliore d'activation d'oocytes
CA2043088A1 (fr) Methode de clonage d'embryons de mammiferes
Ogura et al. Microinsemination using spermatogenic cells in mammals
McLaughlin Factors in the production of identical animals by nuclear transfer
JP2004016115A (ja) 効率的に体細胞から動物個体を生産する方法
JP2004519226A (ja) 核移植胚の活性化
AU4277400A (en) A process of cell reprogramming through production of a heterokaryon

Legal Events

Date Code Title Description
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: GRACE & CO.-CONN. W.R. -

BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: ABS GLOBAL, INC.

CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: INFIGEN, INC. A DELAWARE CORPORATION;PROTEIN GENETICS, INC. A DELAWARE CORPORATION

BN A decision not to publish the application has become irrevocable