NL8302562A - Gesubstitueerde peptideverbindingen. - Google Patents

Gesubstitueerde peptideverbindingen. Download PDF

Info

Publication number
NL8302562A
NL8302562A NL8302562A NL8302562A NL8302562A NL 8302562 A NL8302562 A NL 8302562A NL 8302562 A NL8302562 A NL 8302562A NL 8302562 A NL8302562 A NL 8302562A NL 8302562 A NL8302562 A NL 8302562A
Authority
NL
Netherlands
Prior art keywords
formula
group
hydrogen
short chain
chain alkyl
Prior art date
Application number
NL8302562A
Other languages
English (en)
Dutch (nl)
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of NL8302562A publication Critical patent/NL8302562A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NL8302562A 1982-07-19 1983-07-18 Gesubstitueerde peptideverbindingen. NL8302562A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39965082A 1982-07-19 1982-07-19
US39965082 1982-07-19

Publications (1)

Publication Number Publication Date
NL8302562A true NL8302562A (nl) 1984-02-16

Family

ID=23580391

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8302562A NL8302562A (nl) 1982-07-19 1983-07-18 Gesubstitueerde peptideverbindingen.

Country Status (21)

Country Link
JP (3) JPS5951246A (it)
KR (1) KR840005709A (it)
AU (1) AU1643283A (it)
BE (1) BE897327A (it)
CA (1) CA1244006A (it)
CH (1) CH659475A5 (it)
DE (1) DE3325850A1 (it)
DK (1) DK330683A (it)
ES (4) ES524200A0 (it)
FI (1) FI832620A (it)
FR (3) FR2530238B1 (it)
GB (1) GB2123834B (it)
GR (1) GR79602B (it)
HU (1) HU187090B (it)
IE (1) IE55818B1 (it)
IL (1) IL69136A0 (it)
IT (1) IT1163800B (it)
NL (1) NL8302562A (it)
PT (1) PT77045B (it)
SE (1) SE8304031L (it)
ZA (1) ZA834980B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55159749A (en) * 1979-05-31 1980-12-12 Takeda Chem Ind Ltd Preparation of dried fish flesh
US4500518A (en) * 1984-04-19 1985-02-19 E. R. Squibb & Sons, Inc. Amino thiol dipeptides
DE3588094T2 (de) * 1984-09-12 1996-08-22 Rhone Poulenc Rorer Pharma Antihypertensive Derivate
US4629724A (en) * 1984-12-03 1986-12-16 E. R. Squibb & Sons, Inc. Amino acid ester and amide renin inhibitors
FR2578544A1 (en) * 1985-03-11 1986-09-12 Usv Pharma Corp Antihypertension spirocyclic compounds
FI89058C (fi) * 1987-02-27 1993-08-10 Yamanouchi Pharma Co Ltd Foerfarande foer framstaellning av som remin-inhibitorer anvaenda 2-(l-alanyl-l-histidylamino)-butanol-derivat
US6858565B2 (en) 2001-05-14 2005-02-22 Oji Paper Co., Ltd. Thermosensitive recording material and novel color developer compounds
EP3414099A1 (en) 2017-01-10 2018-12-19 Mitsubishi HiTec Paper Europe GmbH Novel colour developer for a thermo-sensitive recording medium, and a heat-sensitive recording material based on pla

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3751239A (en) * 1969-05-29 1973-08-07 Rohm & Haas Herbicidal compositions containing n-(1,1-dialkyl-3-chloroacetonyl) benzamides
JPS5430167A (en) * 1977-08-11 1979-03-06 Mitsubishi Chem Ind Ltd 4-aminomethyl-2-phenyloxazoles and their pharmaceutically acceptable acid salts
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
IE51409B1 (en) * 1980-07-24 1986-12-24 Ici Ltd Amide derivatives
GR75019B (it) * 1980-09-17 1984-07-12 Univ Miami
DE19575012I2 (de) * 1980-10-23 2002-01-24 Schering Corp Carboxyalkyl-Dipeptide Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
CY1406A (en) * 1980-12-18 1988-04-22 Schering Corp Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
US4514391A (en) * 1983-07-21 1985-04-30 E. R. Squibb & Sons, Inc. Hydroxy substituted peptide compounds

Also Published As

Publication number Publication date
HUT34040A (en) 1985-01-28
GB2123834A (en) 1984-02-08
AU1643283A (en) 1984-01-26
BE897327A (fr) 1984-01-19
FR2540866A1 (fr) 1984-08-17
FR2530238B1 (it) 1989-06-30
JPH0526775B2 (it) 1993-04-19
ZA834980B (en) 1984-03-28
SE8304031D0 (sv) 1983-07-18
ES8707549A1 (es) 1986-04-01
GB2123834B (en) 1986-10-22
GB8318492D0 (en) 1983-08-10
JPH0532601A (ja) 1993-02-09
IT8322114A0 (it) 1983-07-18
ES539084A0 (es) 1986-04-01
ES8504675A1 (es) 1985-04-16
PT77045A (en) 1983-08-01
GR79602B (it) 1984-10-31
FR2540867A1 (fr) 1984-08-17
FI832620A (fi) 1984-01-20
DK330683A (da) 1984-01-20
FI832620A0 (fi) 1983-07-19
HU187090B (en) 1985-11-28
PT77045B (en) 1986-02-12
DK330683D0 (da) 1983-07-18
IT1163800B (it) 1987-04-08
ES8707550A1 (es) 1986-04-01
DE3325850A1 (de) 1984-01-19
IE831655L (en) 1984-01-19
ES539082A0 (es) 1986-05-16
SE8304031L (sv) 1984-03-30
IL69136A0 (en) 1983-10-31
IE55818B1 (en) 1991-01-30
ES539083A0 (es) 1986-04-01
ES524200A0 (es) 1985-04-16
ES8707548A1 (es) 1986-05-16
JPH0645582B2 (ja) 1994-06-15
CA1244006A (en) 1988-11-01
JPH0653713B2 (ja) 1994-07-20
CH659475A5 (fr) 1987-01-30
JPS5951246A (ja) 1984-03-24
KR840005709A (ko) 1984-11-16
FR2540867B1 (fr) 1987-07-31
JPH0517420A (ja) 1993-01-26
FR2530238A1 (it) 1984-01-20

Similar Documents

Publication Publication Date Title
KR100561504B1 (ko) 인터류킨-1 베타 전환 효소의 억제제
KR100637110B1 (ko) 세포 유착 억제제
FI86192C (fi) Stereoselektiv foerfarande foer framstaellning av omaettad laktoner.
CS237311B2 (en) Processing of carboxyalkyldipeptide
JPS6049000A (ja) ヒドロキシ置換ペプチド化合物
BG63634B1 (bg) Инхибитори на интерлевкин 1 бета-конвертиращ ензим
NO861141L (no) Fremgangsmaate ved fremstilling av therapeutisk virksomme n,n[-dialkylguanidino-dipeptider.
EP0315815A1 (en) Branched backbone renin inhibitors
JPH07300479A (ja) ベンゾ縮合ラクタム類
EA002419B1 (ru) Антагонисты рецептора витронектина
EP0303434A1 (en) Thiazolidine compounds
GB2210043A (en) Phosphinylcycloalkylcarbonyl and phosphinylcycloalkenylcarbonyl dipeptides
EP0405506A1 (en) Tetrapeptide type-B CCK receptor ligands
EP0142335A2 (en) Lactam containing compounds
EP0296581A2 (en) Amino acid 1,2-diketo derivatives as renin inhibitors
NL8302562A (nl) Gesubstitueerde peptideverbindingen.
US4711884A (en) Thiazine and thiazepine containing compounds
JPH02500025A (ja) 新規なｃ末端基を有するレニン抑制ペプチド
JPS617295A (ja) メルカプトシクロアルキルカルボニルおよびメルカプトアリールカルボニルジペプチド類
JPH0688989B2 (ja) アシルアミノオキソまたはヒドロキシ置換アルキルアミノチアジン類およびチアゼピン類
JPH0656807A (ja) ３（ｓ）−アミノ−４−シクロヘキシル−２（ｒ）−ヒドロキシ−ブタン酸または４−シクロヘキシル−（２ｒ，３ｓ）−ジヒドロキシブタン酸または関連するジオール類似体若しくはヒドロキシケトン類似体を含む、及びｌ−セリンまたは関連する類似体をｐ２位に有する環状レニン阻害剤
JPH04504716A (ja) 新規な極性ｎ―末端基を有するペプチド類
NZ233811A (en) Amino-substituted heterocycles having renin inhibitory action
US4568489A (en) N-Acyl-γ-glutamyl imino and amino acids and esters
US4456595A (en) Carboxy and substituted carboxy aroly peptides

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed