NL8002096A - Injecteerbare stabiele geneesmiddeloplossing met ontstekingremmende werking. - Google Patents
Injecteerbare stabiele geneesmiddeloplossing met ontstekingremmende werking. Download PDFInfo
- Publication number
- NL8002096A NL8002096A NL8002096A NL8002096A NL8002096A NL 8002096 A NL8002096 A NL 8002096A NL 8002096 A NL8002096 A NL 8002096A NL 8002096 A NL8002096 A NL 8002096A NL 8002096 A NL8002096 A NL 8002096A
- Authority
- NL
- Netherlands
- Prior art keywords
- solution
- indole
- phosphatidylcholine
- water
- indomethacin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
- A61K47/544—Phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792914789 DE2914789A1 (de) | 1979-04-11 | 1979-04-11 | Injizierbare arzneimittel mit entzuendungshemmender wirkung |
| DE2914789 | 1979-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8002096A true NL8002096A (nl) | 1980-10-14 |
Family
ID=6068138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8002096A NL8002096A (nl) | 1979-04-11 | 1980-04-10 | Injecteerbare stabiele geneesmiddeloplossing met ontstekingremmende werking. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4309420A (sv) |
| JP (1) | JPS55147217A (sv) |
| AT (1) | AT369650B (sv) |
| AU (1) | AU539043B2 (sv) |
| BE (1) | BE882732A (sv) |
| CA (1) | CA1136048A (sv) |
| CH (1) | CH642547A5 (sv) |
| DE (1) | DE2914789A1 (sv) |
| FR (1) | FR2453646A1 (sv) |
| GB (1) | GB2047535B (sv) |
| IT (1) | IT1148791B (sv) |
| NL (1) | NL8002096A (sv) |
| SE (1) | SE451428B (sv) |
| ZA (1) | ZA802158B (sv) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3042365C2 (de) * | 1980-11-10 | 1987-01-29 | Extrakta Strauss GmbH, 2000 Hamburg | Flüssige, lecithinhaltige einphasige Mehrstoffsysteme und Verfahren zu ihrer Herstellung |
| JPS59152348A (ja) * | 1983-02-19 | 1984-08-31 | Kaken Pharmaceut Co Ltd | ビフエニリルプロピオン酸エステル誘導体およびその製造法 |
| US5196567A (en) * | 1983-02-19 | 1993-03-23 | Kaken Pharmaceutical Co., Ltd. | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same |
| CA1237670A (en) * | 1983-05-26 | 1988-06-07 | Andrew S. Janoff | Drug preparations of reduced toxicity |
| US5059591B1 (en) * | 1983-05-26 | 2000-04-25 | Liposome Co Inc | Drug preparations of reduced toxicity |
| JPS601122A (ja) * | 1983-06-20 | 1985-01-07 | Green Cross Corp:The | ビフエニリルプロピオン酸誘導体脂肪乳剤 |
| PT78628B (en) * | 1984-05-02 | 1986-06-18 | Liposome Co Inc | Pharmaceutical composition with reduced toxicity |
| IL79114A (en) * | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
| IT1269569B (it) * | 1994-04-22 | 1997-04-08 | Ugo Citernesi | Procedimento per la preparazione di complessi fra fosfolipidi e principi attivi utili per la produzione di liposomi e principi attivi e liposomi ottenuti con il procedimento |
| US5763422A (en) | 1995-01-27 | 1998-06-09 | Board Of Regents, The University Of Texas System | Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein |
| ATE218872T1 (de) * | 1995-01-27 | 2002-06-15 | Univ Texas | Verfahren zur erhöhung der therapeutischen wirkung von nsaids und dazu verwendbare zwitterionische phospholipidhaltige zusammensetungen |
| US5955451A (en) * | 1995-05-12 | 1999-09-21 | The University Of Texas System Board Of Regents | Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein |
| US20040077604A1 (en) * | 2001-12-19 | 2004-04-22 | Lenard Lichtenberger | Method and compositions employing formulations of lecithin oils and nsaids for protecting the gastrointestinal tract and providingenhanced therapeutic activity |
| US9730884B2 (en) | 2011-09-29 | 2017-08-15 | Plx Opco Inc. | pH dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same |
| JP2023518822A (ja) | 2020-03-26 | 2023-05-08 | ピーエルエックス オプコ インコーポレイテッド | ｐＨ依存的再構築が可能な医薬キャリア、その製造方法及び使用方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA725596A (en) * | 1960-08-26 | 1966-01-11 | J. Wretlind Arvid | Method of preparing intravenously injectable fat emulsions free from side reactions or complications |
| GB1214515A (en) * | 1967-04-11 | 1970-12-02 | Sumitomi Chemical Company Ltd | Indole derivatives and salts thereof |
| JPS5186117A (en) * | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
| GB1523965A (en) * | 1976-03-19 | 1978-09-06 | Ici Ltd | Pharmaceutical compositions containing steroids |
| US4093733A (en) * | 1976-09-09 | 1978-06-06 | Merck & Co., Inc. | Parenteral suspensions |
| GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
| DE2856333C2 (de) * | 1978-12-27 | 1983-09-22 | A. Nattermann & Cie GmbH, 5000 Köln | Oral einnehmbare Arzneimittel mit entzündungshemmender Wirkung |
-
1979
- 1979-04-11 DE DE19792914789 patent/DE2914789A1/de active Granted
-
1980
- 1980-04-08 CA CA000349306A patent/CA1136048A/en not_active Expired
- 1980-04-08 GB GB8011633A patent/GB2047535B/en not_active Expired
- 1980-04-09 FR FR8007938A patent/FR2453646A1/fr active Granted
- 1980-04-10 AT AT0194780A patent/AT369650B/de not_active IP Right Cessation
- 1980-04-10 CH CH274580A patent/CH642547A5/de not_active IP Right Cessation
- 1980-04-10 IT IT21300/80A patent/IT1148791B/it active
- 1980-04-10 ZA ZA00802158A patent/ZA802158B/xx unknown
- 1980-04-10 NL NL8002096A patent/NL8002096A/nl not_active Application Discontinuation
- 1980-04-10 SE SE8002715A patent/SE451428B/sv not_active IP Right Cessation
- 1980-04-10 JP JP4632280A patent/JPS55147217A/ja active Granted
- 1980-04-10 BE BE0/200183A patent/BE882732A/fr not_active IP Right Cessation
- 1980-04-10 US US06/139,117 patent/US4309420A/en not_active Expired - Lifetime
- 1980-04-10 AU AU57330/80A patent/AU539043B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| GB2047535B (en) | 1983-10-26 |
| JPS55147217A (en) | 1980-11-17 |
| DE2914789A1 (de) | 1980-10-16 |
| CH642547A5 (de) | 1984-04-30 |
| FR2453646B1 (sv) | 1985-01-25 |
| BE882732A (fr) | 1980-07-31 |
| DE2914789C2 (sv) | 1991-05-29 |
| SE8002715L (sv) | 1980-10-12 |
| US4309420A (en) | 1982-01-05 |
| AU5733080A (en) | 1980-10-16 |
| IT1148791B (it) | 1986-12-03 |
| CA1136048A (en) | 1982-11-23 |
| FR2453646A1 (fr) | 1980-11-07 |
| AT369650B (de) | 1983-01-25 |
| GB2047535A (en) | 1980-12-03 |
| ATA194780A (de) | 1982-06-15 |
| IT8021300A0 (it) | 1980-04-10 |
| SE451428B (sv) | 1987-10-12 |
| JPH0210805B2 (sv) | 1990-03-09 |
| AU539043B2 (en) | 1984-09-06 |
| ZA802158B (en) | 1981-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| BV | The patent application has lapsed |