NL7902136A - Ornithine- en argininezouten van keto-analogen van onontbeerlijke aminozuren met vertakte keten met farmacologische werking. - Google Patents

Ornithine- en argininezouten van keto-analogen van onontbeerlijke aminozuren met vertakte keten met farmacologische werking.

Info

Publication number
NL7902136A
NL7902136A NL7902136A NL7902136A NL7902136A NL 7902136 A NL7902136 A NL 7902136A NL 7902136 A NL7902136 A NL 7902136A NL 7902136 A NL7902136 A NL 7902136A NL 7902136 A NL7902136 A NL 7902136A
Authority
NL
Netherlands
Prior art keywords
inexpectible
analoges
ornithine
keto
amino acids
Prior art date
Application number
NL7902136A
Other languages
English (en)
Dutch (nl)
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of NL7902136A publication Critical patent/NL7902136A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL7902136A 1978-03-17 1979-03-19 Ornithine- en argininezouten van keto-analogen van onontbeerlijke aminozuren met vertakte keten met farmacologische werking. NL7902136A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/887,570 US4228099A (en) 1978-03-17 1978-03-17 Ornithine and arginine salts of branched chain keto acids and uses in treatment of hepatic and renal disorders

Publications (1)

Publication Number Publication Date
NL7902136A true NL7902136A (nl) 1979-09-19

Family

ID=25391422

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7902136A NL7902136A (nl) 1978-03-17 1979-03-19 Ornithine- en argininezouten van keto-analogen van onontbeerlijke aminozuren met vertakte keten met farmacologische werking.

Country Status (17)

Country Link
US (1) US4228099A (cg-RX-API-DMAC7.html)
JP (1) JPS5838421B2 (cg-RX-API-DMAC7.html)
AU (1) AU517505B2 (cg-RX-API-DMAC7.html)
BE (1) BE874900A (cg-RX-API-DMAC7.html)
CA (1) CA1115729A (cg-RX-API-DMAC7.html)
DE (1) DE2910221A1 (cg-RX-API-DMAC7.html)
DK (1) DK153542C (cg-RX-API-DMAC7.html)
ES (1) ES478710A1 (cg-RX-API-DMAC7.html)
FI (1) FI72118C (cg-RX-API-DMAC7.html)
FR (1) FR2419723A1 (cg-RX-API-DMAC7.html)
GB (1) GB2017094B (cg-RX-API-DMAC7.html)
IE (1) IE48336B1 (cg-RX-API-DMAC7.html)
IT (1) IT1202904B (cg-RX-API-DMAC7.html)
LU (1) LU81057A1 (cg-RX-API-DMAC7.html)
NL (1) NL7902136A (cg-RX-API-DMAC7.html)
NO (1) NO151119C (cg-RX-API-DMAC7.html)
SE (1) SE446724B (cg-RX-API-DMAC7.html)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4296127A (en) * 1979-04-18 1981-10-20 The Johns Hopkins University Mixed salts of essential or semi-essential amino acids and nitrogen-free analogs thereof
DE3438455A1 (de) * 1984-10-19 1986-06-26 Institut Dr. Ziegler, Bettingen L-lysin- und l-histidinpyruvat
US4677121A (en) * 1985-01-22 1987-06-30 The Johns Hopkins University Method of inhibiting muscle protein degradation
US4752619A (en) * 1985-12-23 1988-06-21 The Johns Hopkins University Nutritional supplement for treatment of uremia
US4744990A (en) * 1986-09-25 1988-05-17 W. R. Grace & Co. Hydantoins as animal food supplements
US4871552A (en) * 1986-09-25 1989-10-03 W. R. Grace & Co.-Conn. Hydantoins as animal food supplements
US5639731A (en) * 1987-05-22 1997-06-17 Pripps Bryggerier Ab Amino acids for the preparation of a beverage
FR2615734B1 (fr) * 1987-05-27 1989-12-01 Synthelabo Compositions pharmaceutiques contenant un melange de sels de cetoacides et d'amino-acides utiles pour le traitement de l'uremie
FR2618331B1 (fr) * 1987-07-23 1991-10-04 Synthelabo Compositions pharmaceutiques utiles pour le traitement de l'uremie
AT393079B (de) * 1989-03-06 1991-08-12 Lubec Gert Pharmazeutische verwendung von agmatin
AT393080B (de) * 1988-11-25 1991-08-12 Lubec Gert Pharmazeutische verwendung von arginin (salzen)
SE462463B (sv) * 1988-12-02 1990-07-02 Decken Alexandra V D Livs- och fodermedel innehaallande ketosyror
JP2522034B2 (ja) * 1988-12-27 1996-08-07 味の素株式会社 α−ケト酸・アミノ酸塩化合物及びその製造方法
US5210098A (en) * 1990-09-21 1993-05-11 Regents Of The University Of Minnesota Use of pyruvate to treat acute renal failure
US5234696A (en) * 1991-12-27 1993-08-10 Abbott Laboratories Method of producing tablets, tablets produced thereby, and method of treatment using same
ATE235166T1 (de) 1994-10-07 2003-04-15 Firmenich & Cie Aromazusammensetzungen und aromatisierungsverfahren
US5591736A (en) * 1995-07-03 1997-01-07 The Johns Hopkins University Method of retarding the progression of chronic renal failure
JP2004527529A (ja) * 2001-04-04 2004-09-09 クリティカル セラピューティックス インコーポレイテッド 急性腎不全を予防するための方法
WO2006051940A1 (ja) * 2004-11-15 2006-05-18 Kyowa Hakko Kogyo Co., Ltd. Ｌ－オルニチン結晶およびその製造方法
GB0426141D0 (en) * 2004-11-26 2004-12-29 Ucl Biomedica Plc Treatment
MX2007006171A (es) 2004-11-26 2007-10-08 Ucl Business Plc Composiciones que comprenden ornitina y acetato.
EP3263100B1 (en) * 2009-04-03 2020-04-01 Ocera Therapeutics, Inc. L-ornithine phenyl acetate and methods of making thereof
KR101715008B1 (ko) 2009-06-08 2017-03-22 유씨엘 비즈니스 피엘씨 Ｌ―오르니틴 페닐아세테이트를 사용한 문맥압 항진증의 치료 및 간 기능 회복
EP2625162B1 (en) 2010-10-06 2019-03-13 Ocera Therapeutics, Inc. Methods of making l-ornithine phenyl acetate
CA2968544A1 (en) 2014-11-24 2016-06-02 Ucl Business Plc Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
EP3337473A4 (en) 2015-08-18 2019-04-17 Ocera Therapeutics, Inc. TREATMENT AND PREVENTION OF MUSCLE WOUND BY L-ORNITHIN IN COMBINATION WITH AT LEAST ONE PHENYL ACETATE AND PHENYL BUTYRATE
CN106674057A (zh) * 2015-11-09 2017-05-17 江西乐维生物药业有限公司 L-精氨酸a-酮基异己酸盐的制备方法
US11219611B2 (en) 2015-11-13 2022-01-11 Ocera Therapeutics, Inc. Formulations of L-ornithine phenylacetate
WO2017090007A1 (en) * 2015-11-29 2017-06-01 Rao M Surya Compositions and methods for the treatment of urea cycle disorders and hepatic diseases
AU2018266357B2 (en) 2017-05-11 2022-12-08 Ocera Therapeutics, Inc. Processes of making L-ornithine phenylacetate
WO2019108809A2 (en) 2017-11-29 2019-06-06 Hull Edgar L Jr Alpha keto acid compositions for treating hypo-albuminemia
US12109254B2 (en) 2017-11-29 2024-10-08 Edgar Hull Vitamins and alpha keto acid compositions for use in a treatment program for chronic kidney disease patients
US11484579B2 (en) 2017-11-29 2022-11-01 Edgar L Hull Vitamins and alpha keto acid compositions for use in a treatment program for chronic kidney disease patients

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA814483A (en) * 1969-06-03 Abe Kyuji L-ornithine-l-aspartate
GB1034358A (en) 1963-05-01 1966-06-29 Chugai Pharmaceutical Co Ltd Body-protein-biosynthesis promoting composition
FR1432756A (fr) 1965-02-11 1966-03-25 D Opochimiotherapie Lab Pyruvates d'amino-acides et leur procédé de préparation
US3441650A (en) * 1965-07-23 1969-04-29 Lab Jacques Logeais Sa Therapy of ammonical intoxications by di-l-ornithine alpha-ketoglutarate
DE2335215B2 (de) 1972-07-13 1979-04-05 The Johns Hopkins University, Baltimore, Md. (V.St.A.) Verwendung einer Mischung bei der Bekämpfung von zur Urämie führenden Nierenerkrankungen
US4100161A (en) * 1974-04-15 1978-07-11 The Johns Hopkins University Promotion of protein synthesis and suppression of urea formation in the body by keto analogs of essential amino acids
US3950529A (en) * 1975-02-03 1976-04-13 Massachusetts General Hospital Amino acid formulations for patients with liver disease and method of using same

Also Published As

Publication number Publication date
SE7902401L (sv) 1979-10-16
NO790903L (no) 1979-09-18
IE48336B1 (en) 1984-12-12
DE2910221A1 (de) 1979-09-20
US4228099A (en) 1980-10-14
AU517505B2 (en) 1981-08-06
ES478710A1 (es) 1980-01-16
FR2419723A1 (fr) 1979-10-12
CA1115729A (en) 1982-01-05
BE874900A (fr) 1979-07-16
DK153542B (da) 1988-07-25
DE2910221C2 (cg-RX-API-DMAC7.html) 1988-04-28
IE790993L (en) 1979-09-17
FR2419723B1 (cg-RX-API-DMAC7.html) 1982-10-29
LU81057A1 (fr) 1979-09-07
NO151119C (no) 1985-02-13
FI72118C (fi) 1987-04-13
DK153542C (da) 1988-12-05
JPS5838421B2 (ja) 1983-08-23
DK110879A (da) 1979-09-18
GB2017094A (en) 1979-10-03
IT1202904B (it) 1989-02-15
JPS54163518A (en) 1979-12-26
GB2017094B (en) 1982-07-07
IT7921071A0 (it) 1979-03-16
SE446724B (sv) 1986-10-06
NO151119B (no) 1984-11-05
FI790901A7 (fi) 1979-09-18
AU4515479A (en) 1979-09-20
FI72118B (fi) 1986-12-31

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Legal Events

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A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
A85 Still pending on 85-01-01
BC A request for examination has been filed
BV The patent application has lapsed