NL7805267A - Sterolverbindingen, die op de plaats 15 een zuurstof bevattende groep bezitten. - Google Patents
Sterolverbindingen, die op de plaats 15 een zuurstof bevattende groep bezitten.Info
- Publication number
- NL7805267A NL7805267A NL7805267A NL7805267A NL7805267A NL 7805267 A NL7805267 A NL 7805267A NL 7805267 A NL7805267 A NL 7805267A NL 7805267 A NL7805267 A NL 7805267A NL 7805267 A NL7805267 A NL 7805267A
- Authority
- NL
- Netherlands
- Prior art keywords
- place
- sterol compounds
- oxygen
- compounds containing
- containing group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/797,345 US4202891A (en) | 1977-05-16 | 1977-05-16 | 15-Oxygenated sterol compounds and the use of such compounds to inhibit the biosynthesis of sterols |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7805267A true NL7805267A (nl) | 1978-11-20 |
Family
ID=25170577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7805267A NL7805267A (nl) | 1977-05-16 | 1978-05-16 | Sterolverbindingen, die op de plaats 15 een zuurstof bevattende groep bezitten. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4202891A (xx) |
JP (1) | JPS5455734A (xx) |
AU (1) | AU520703B2 (xx) |
BE (1) | BE867120A (xx) |
CA (1) | CA1123739A (xx) |
CH (1) | CH641352A5 (xx) |
DE (3) | DE2858726C2 (xx) |
FR (2) | FR2390960B1 (xx) |
GB (1) | GB1599863A (xx) |
IT (1) | IT1156745B (xx) |
NL (1) | NL7805267A (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS563000A (en) * | 1979-06-20 | 1981-01-13 | Green Cross Corp:The | Water-soluble cholesterol derivative |
US5034548A (en) * | 1987-01-30 | 1991-07-23 | E. I. Du Pont De Nemours And Company | Steroid derivatives useful as hypocholesterolemics |
EP0276823B1 (en) * | 1987-01-30 | 1992-09-23 | The Du Pont Merck Pharmaceutical Company | 14,15-substituted lanosterols and their use as hypocholesterolemic agents |
US5041432A (en) * | 1987-01-30 | 1991-08-20 | E. I. Du Pont De Nemours And Company | Steroid derivatives useful as hypocholesterolemics |
DE3705990A1 (de) * | 1987-02-20 | 1988-09-01 | Schering Ag | 1-methyl-15(alpha)-(1-oxyalkyl)-androsta-1,4-dien- 3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate |
US4897475A (en) * | 1988-02-05 | 1990-01-30 | William Marsh Rice University | Process for synthesis of 5α-cholest-8(14)-en-3β-ol-15-one and other 15-oxygenated sterols |
US4900477A (en) * | 1988-03-28 | 1990-02-13 | American Cyanamid Company | Novel intermediates and an improved process for producing the compound (3β,5α)-3-hydroxycholest-8(14)-en-15-one |
US5023250A (en) * | 1989-08-24 | 1991-06-11 | Smithkline Beecham Corporation | Steroidal 14α-carboxy-alkyl derivatives as regulators of HMG-COA reductase |
US5219879A (en) * | 1990-03-05 | 1993-06-15 | Du Pont Merck Pharmaceutical Company | Heterocyclic steroid compounds |
JP3029907B2 (ja) * | 1991-12-20 | 2000-04-10 | 理化学研究所 | 抗肥満剤 |
US5510340A (en) * | 1992-06-12 | 1996-04-23 | Sri International | Antihypercholesterolemic compounds and related pharmaceutical compositions and methods of use |
US5371077A (en) * | 1992-08-03 | 1994-12-06 | William Marsh Rice University | Side chain derivatized 15-oxygenated sterols, methods of using them and a process for preparing them |
JP3862295B2 (ja) * | 1993-09-30 | 2006-12-27 | 独立行政法人理化学研究所 | 抗肥満剤 |
CA2373442A1 (en) * | 1999-05-10 | 2000-11-16 | Schering Aktiengesellschaft | 14.beta.-h-sterols, pharmaceutical compositions comprising them and use of these derivatives for the preparation of meiosis regulating medicaments |
US8399441B2 (en) * | 2004-10-25 | 2013-03-19 | Virginia Commonwealth University | Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis |
WO2006047022A1 (en) | 2004-10-25 | 2006-05-04 | Virginia Commonwealth University | Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis |
US9034859B2 (en) | 2011-04-06 | 2015-05-19 | Virginia Commonwealth University | Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation |
KR20240051283A (ko) | 2013-12-24 | 2024-04-19 | 버지니아 커먼웰스 유니버시티 | 산소첨가된 콜레스테롤 술페이트 (ocs) 의 용도 |
JP2019524772A (ja) | 2016-08-02 | 2019-09-05 | ヴァージニア コモンウェルス ユニバーシティ | 5−コレステン−3,25−ジオール,3−サルフェート(25hc3s)又は薬学的に許容される塩及び少なくとも1種の環状オリゴ糖を含む組成物 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1493252A1 (de) * | 1963-11-01 | 1969-06-26 | Takeda Chemical Industries Ltd | Verfahren zur Herstellung von 13beta-Alkyl-14-Hydroxygona-1,3,5(10),9(11)-tetraenen |
US3354154A (en) * | 1966-01-26 | 1967-11-21 | Syntex Corp | 2beta, 3beta-alkylidenedioxy-6-hydroxy-22, 23-bisnorchol-7-enoic acid alkyl esters and process for the production thereof |
-
1977
- 1977-05-16 US US05/797,345 patent/US4202891A/en not_active Expired - Lifetime
-
1978
- 1978-05-15 CA CA303,354A patent/CA1123739A/en not_active Expired
- 1978-05-16 NL NL7805267A patent/NL7805267A/xx not_active Application Discontinuation
- 1978-05-16 IT IT49386/78A patent/IT1156745B/it active
- 1978-05-16 CH CH528378A patent/CH641352A5/de not_active IP Right Cessation
- 1978-05-16 AU AU36167/78A patent/AU520703B2/en not_active Expired
- 1978-05-16 BE BE187736A patent/BE867120A/xx not_active IP Right Cessation
- 1978-05-16 DE DE2858726A patent/DE2858726C2/de not_active Expired - Fee Related
- 1978-05-16 FR FR7814450A patent/FR2390960B1/fr not_active Expired
- 1978-05-16 JP JP5816378A patent/JPS5455734A/ja active Granted
- 1978-05-16 GB GB19939/78A patent/GB1599863A/en not_active Expired
- 1978-05-16 DE DE2858802A patent/DE2858802C2/de not_active Expired - Fee Related
- 1978-05-16 DE DE19782821242 patent/DE2821242A1/de active Granted
-
1981
- 1981-08-21 FR FR8116129A patent/FR2485021A1/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
AU3616778A (en) | 1979-11-22 |
CA1123739A (en) | 1982-05-18 |
DE2821242C2 (xx) | 1991-10-24 |
IT1156745B (it) | 1987-02-04 |
GB1599863A (en) | 1981-10-07 |
BE867120A (fr) | 1978-09-18 |
JPS5455734A (en) | 1979-05-04 |
DE2858726C2 (de) | 1992-10-01 |
IT7849386A0 (it) | 1978-05-16 |
AU520703B2 (en) | 1982-02-25 |
CH641352A5 (de) | 1984-02-29 |
FR2390960A1 (fr) | 1978-12-15 |
DE2821242A1 (de) | 1978-11-23 |
FR2485021A1 (fr) | 1981-12-24 |
DE2858802C2 (de) | 1991-10-02 |
FR2390960B1 (fr) | 1985-11-29 |
US4202891A (en) | 1980-05-13 |
JPH0214329B2 (xx) | 1990-04-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A85 | Still pending on 85-01-01 | ||
BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
BV | The patent application has lapsed |