IT8020508A0 - 24,24-difluoro-1alfa,25-diidrossicolecalciferolo. - Google Patents

24,24-difluoro-1alfa,25-diidrossicolecalciferolo.

Info

Publication number
IT8020508A0
IT8020508A0 IT8020508A IT2050880A IT8020508A0 IT 8020508 A0 IT8020508 A0 IT 8020508A0 IT 8020508 A IT8020508 A IT 8020508A IT 2050880 A IT2050880 A IT 2050880A IT 8020508 A0 IT8020508 A0 IT 8020508A0
Authority
IT
Italy
Prior art keywords
1alfa
dihydroxycholecalciferol
difluoro
Prior art date
Application number
IT8020508A
Other languages
English (en)
Other versions
IT1140776B (it
Inventor
Heinrich K Schnoes
Hector F Delluca
Ikekawa Nobuo
Tanaka Yoko
Kobayashi Yoshiro
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IT8020508A0 publication Critical patent/IT8020508A0/it
Application granted granted Critical
Publication of IT1140776B publication Critical patent/IT1140776B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/48—Halogenated derivatives
    • C07C35/52—Alcohols with a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT20508/80A 1979-03-28 1980-03-11 24,24-difluoro-1, alfa,25-diidrossicolecalciferolo IT1140776B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/024,848 US4201881A (en) 1979-03-28 1979-03-28 24,24-Difluoro-1α,25-dihydroxycholecalciferol

Publications (2)

Publication Number Publication Date
IT8020508A0 true IT8020508A0 (it) 1980-03-11
IT1140776B IT1140776B (it) 1986-10-10

Family

ID=21822707

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20508/80A IT1140776B (it) 1979-03-28 1980-03-11 24,24-difluoro-1, alfa,25-diidrossicolecalciferolo

Country Status (15)

Country Link
US (1) US4201881A (it)
JP (2) JPS6342618B2 (it)
AU (1) AU530015B2 (it)
BE (1) BE882143A (it)
CH (1) CH650240A5 (it)
DK (1) DK147300C (it)
FR (1) FR2452481A1 (it)
GB (2) GB2067567B (it)
IE (1) IE49753B1 (it)
IL (1) IL58526A (it)
IT (1) IT1140776B (it)
NL (1) NL7920190A (it)
NZ (1) NZ191900A (it)
SE (1) SE8008339L (it)
WO (1) WO1980002028A1 (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same
ZA826210B (en) * 1981-08-28 1983-07-27 Hoffmann La Roche Cholecalciferol derivatives
EP0094644B1 (de) * 1982-05-17 1986-07-30 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verwendung eines Cholecalciferolderivates
US4456689A (en) * 1982-05-17 1984-06-26 Becton Dickinson And Company Competitive protein binding assay using an organosilane-silica gel separation medium
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
JPS6253960A (ja) * 1985-05-30 1987-03-09 Taisho Pharmaceut Co Ltd ビタミンｄ↓３の誘導体
EP0245524B1 (en) * 1985-11-21 1991-04-17 Taisho Pharmaceutical Co. Ltd Vitamin d 3 derivative
US4853378A (en) * 1986-10-20 1989-08-01 Sumitomo Chemical Company, Limited Fluorine derivatives of vitamin D3 and process for producing the same
US5316770A (en) * 1989-02-16 1994-05-31 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
AU5185790A (en) * 1989-02-16 1990-09-05 University Of Georgia Research Foundation, Inc., The Treatment of tibial dyschondroplasia
US5366736A (en) * 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5063234A (en) * 1990-05-25 1991-11-05 Eli Lilly And Company Method of inhibiting demineralization of bone
JP2011508743A (ja) * 2007-12-28 2011-03-17 ウィスコンシン アラムナイ リサーチ ファンデーション （２０ｓ）−２３，２３−ジフルオロ−２−メチレン−１９−ノル−ビスホモプレグナカルシフェロール−ビタミンｄ類縁体
JP5504898B2 (ja) 2010-01-08 2014-05-28 セントラル硝子株式会社 ジフルオロシクロプロパン化合物の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol
US3969700A (en) * 1974-04-10 1976-07-13 International Business Machines Corporation Regional context maximum likelihood error correction for OCR, keyboard, and the like
FR2267590B1 (it) * 1974-04-10 1977-05-20 Ibm
JPS5729745B2 (it) * 1974-09-25 1982-06-24
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same

Also Published As

Publication number Publication date
GB2045765B (en) 1983-06-15
GB2067567A (en) 1981-07-30
AU530015B2 (en) 1983-06-30
IE800619L (en) 1980-09-28
FR2452481B1 (it) 1984-10-19
IL58526A (en) 1983-05-15
US4201881A (en) 1980-05-06
IE49753B1 (en) 1985-12-11
NL7920190A (nl) 1981-01-30
GB2067567B (en) 1983-03-02
NZ191900A (en) 1984-11-09
JPS6342618B2 (it) 1988-08-24
IT1140776B (it) 1986-10-10
JPS63179855A (ja) 1988-07-23
BE882143A (fr) 1980-07-01
DK505080A (da) 1980-11-27
GB2045765A (en) 1980-11-05
IL58526A0 (en) 1980-01-31
JPS56500296A (it) 1981-03-12
DK147300C (da) 1984-12-24
CH650240A5 (de) 1985-07-15
WO1980002028A1 (en) 1980-10-02
JPH0146504B2 (it) 1989-10-09
SE8008339L (sv) 1980-11-27
FR2452481A1 (fr) 1980-10-24
AU5581080A (en) 1980-10-02
DK147300B (da) 1984-06-12

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