NL7805267A - Sterolverbindingen, die op de plaats 15 een zuurstof bevattende groep bezitten. - Google Patents

Sterolverbindingen, die op de plaats 15 een zuurstof bevattende groep bezitten.

Info

Publication number
NL7805267A
NL7805267A NL7805267A NL7805267A NL7805267A NL 7805267 A NL7805267 A NL 7805267A NL 7805267 A NL7805267 A NL 7805267A NL 7805267 A NL7805267 A NL 7805267A NL 7805267 A NL7805267 A NL 7805267A
Authority
NL
Netherlands
Prior art keywords
place
sterol compounds
oxygen
compounds containing
containing group
Prior art date
Application number
NL7805267A
Other languages
English (en)
Dutch (nl)
Original Assignee
George John Schroepfer Jr Edwa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by George John Schroepfer Jr Edwa filed Critical George John Schroepfer Jr Edwa
Publication of NL7805267A publication Critical patent/NL7805267A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7805267A 1977-05-16 1978-05-16 Sterolverbindingen, die op de plaats 15 een zuurstof bevattende groep bezitten. NL7805267A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/797,345 US4202891A (en) 1977-05-16 1977-05-16 15-Oxygenated sterol compounds and the use of such compounds to inhibit the biosynthesis of sterols

Publications (1)

Publication Number Publication Date
NL7805267A true NL7805267A (nl) 1978-11-20

Family

ID=25170577

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7805267A NL7805267A (nl) 1977-05-16 1978-05-16 Sterolverbindingen, die op de plaats 15 een zuurstof bevattende groep bezitten.

Country Status (11)

Country Link
US (1) US4202891A (fr)
JP (1) JPS5455734A (fr)
AU (1) AU520703B2 (fr)
BE (1) BE867120A (fr)
CA (1) CA1123739A (fr)
CH (1) CH641352A5 (fr)
DE (3) DE2858726C2 (fr)
FR (2) FR2390960B1 (fr)
GB (1) GB1599863A (fr)
IT (1) IT1156745B (fr)
NL (1) NL7805267A (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS563000A (en) * 1979-06-20 1981-01-13 Green Cross Corp:The Water-soluble cholesterol derivative
EP0276823B1 (fr) * 1987-01-30 1992-09-23 The Du Pont Merck Pharmaceutical Company Lanostérols substitués en 14 et 15 et leur utilisation comme hypocholesterolemiants
US5034548A (en) * 1987-01-30 1991-07-23 E. I. Du Pont De Nemours And Company Steroid derivatives useful as hypocholesterolemics
US5041432A (en) * 1987-01-30 1991-08-20 E. I. Du Pont De Nemours And Company Steroid derivatives useful as hypocholesterolemics
DE3705990A1 (de) * 1987-02-20 1988-09-01 Schering Ag 1-methyl-15(alpha)-(1-oxyalkyl)-androsta-1,4-dien- 3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US4897475A (en) * 1988-02-05 1990-01-30 William Marsh Rice University Process for synthesis of 5α-cholest-8(14)-en-3β-ol-15-one and other 15-oxygenated sterols
US4900477A (en) * 1988-03-28 1990-02-13 American Cyanamid Company Novel intermediates and an improved process for producing the compound (3β,5α)-3-hydroxycholest-8(14)-en-15-one
US5023250A (en) * 1989-08-24 1991-06-11 Smithkline Beecham Corporation Steroidal 14α-carboxy-alkyl derivatives as regulators of HMG-COA reductase
US5219879A (en) * 1990-03-05 1993-06-15 Du Pont Merck Pharmaceutical Company Heterocyclic steroid compounds
JP3029907B2 (ja) * 1991-12-20 2000-04-10 理化学研究所 抗肥満剤
US5510340A (en) * 1992-06-12 1996-04-23 Sri International Antihypercholesterolemic compounds and related pharmaceutical compositions and methods of use
US5371077A (en) * 1992-08-03 1994-12-06 William Marsh Rice University Side chain derivatized 15-oxygenated sterols, methods of using them and a process for preparing them
JP3862295B2 (ja) * 1993-09-30 2006-12-27 独立行政法人理化学研究所 抗肥満剤
SK16212001A3 (sk) * 1999-05-10 2002-02-05 Schering Aktiengesellschaft 14beta-H-steroly, ich použitie ako liečiv a farmaceutické prostriedky, ktoré ich obsahujú
WO2006047022A1 (fr) 2004-10-25 2006-05-04 Virginia Commonwealth University Oxysterol sulfate nucleaire, regulateur homeostatique du cholesterol agissant puissamment dans le traitement de l'hypercholesterolemie, de l'hyperlipidemie et de l'atherosclerose
US8399441B2 (en) 2004-10-25 2013-03-19 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
US9034859B2 (en) 2011-04-06 2015-05-19 Virginia Commonwealth University Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
SI3086793T1 (sl) 2013-12-24 2022-10-28 Virginia Commonwealth University Uporaba oksigeniranih holesterol sulfatov (OCS) za zdravljenje ledvične disfunkcije
JP2019524772A (ja) 2016-08-02 2019-09-05 ヴァージニア コモンウェルス ユニバーシティ ５−コレステン−３，２５−ジオール，３−サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1080333A (en) * 1963-11-01 1967-08-23 Takeda Chemical Industries Ltd New 14-hydroxy steroids
US3354154A (en) * 1966-01-26 1967-11-21 Syntex Corp 2beta, 3beta-alkylidenedioxy-6-hydroxy-22, 23-bisnorchol-7-enoic acid alkyl esters and process for the production thereof

Also Published As

Publication number Publication date
IT7849386A0 (it) 1978-05-16
US4202891A (en) 1980-05-13
CH641352A5 (de) 1984-02-29
BE867120A (fr) 1978-09-18
CA1123739A (fr) 1982-05-18
IT1156745B (it) 1987-02-04
JPH0214329B2 (fr) 1990-04-06
DE2821242A1 (de) 1978-11-23
FR2485021A1 (fr) 1981-12-24
JPS5455734A (en) 1979-05-04
AU3616778A (en) 1979-11-22
AU520703B2 (en) 1982-02-25
FR2390960A1 (fr) 1978-12-15
GB1599863A (en) 1981-10-07
DE2858726C2 (de) 1992-10-01
DE2858802C2 (de) 1991-10-02
FR2390960B1 (fr) 1985-11-29
DE2821242C2 (fr) 1991-10-24

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed