NL7712750A - 1-carba-2-penem-3-carbonzuur en derivaten. - Google Patents

1-carba-2-penem-3-carbonzuur en derivaten.

Info

Publication number
NL7712750A
NL7712750A NL7712750A NL7712750A NL7712750A NL 7712750 A NL7712750 A NL 7712750A NL 7712750 A NL7712750 A NL 7712750A NL 7712750 A NL7712750 A NL 7712750A NL 7712750 A NL7712750 A NL 7712750A
Authority
NL
Netherlands
Prior art keywords
penem
carba
derivatives
carbonic acid
carbonic
Prior art date
Application number
NL7712750A
Other languages
English (en)
Dutch (nl)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL7712750A publication Critical patent/NL7712750A/xx
Priority claimed from AU79443/91A external-priority patent/AU645095B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/04—Preparation by forming the ring or condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Of Gases By Adsorption (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
NL7712750A 1976-11-19 1977-11-18 1-carba-2-penem-3-carbonzuur en derivaten. NL7712750A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74336376A 1976-11-19 1976-11-19
US74337076A 1976-11-19 1976-11-19
US84317177A 1977-10-19 1977-10-19
AU79443/91A AU645095B2 (en) 1976-11-19 1991-07-01 Improved process for recovering organic vapors from air

Publications (1)

Publication Number Publication Date
NL7712750A true NL7712750A (nl) 1978-05-23

Family

ID=27423898

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7712750A NL7712750A (nl) 1976-11-19 1977-11-18 1-carba-2-penem-3-carbonzuur en derivaten.

Country Status (9)

Country Link
EP (1) EP0521203A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS6033836B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH640856A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2751624A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (3) FR2371449B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1593524A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU78538A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7712750A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE436130B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
EP0000828B1 (en) * 1977-08-06 1983-03-09 Beecham Group Plc Synthetic beta-lactam compounds, a process for their preparation and compositions containing them
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
EP0003740B1 (en) * 1978-01-19 1982-01-27 Beecham Group Plc Beta-lactam antibiotics, a process for their preparation and pharmaceutical compositions containing them
US4272439A (en) * 1978-06-02 1981-06-09 Schering Corporation 6-(Substituted-hydroxymethylene penams)
PH16708A (en) 1978-07-24 1984-01-20 Merck & Co Inc Z-2-acylamino-3-monosubstituted propenoates
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
ATE15039T1 (de) * 1979-04-27 1985-09-15 Merck & Co Inc Verfahren zur herstellung von 3-(1-hydroxyaethyl)- azetidinonen.
JPS56142260A (en) * 1980-04-09 1981-11-06 Toyama Chem Co Ltd 2-azetidinone and its preparation
CA1179675A (en) * 1981-01-30 1984-12-18 Erwin Gotschi 7-oxo-1-azabicyclo ¬3,2,0| heptene-2-derivatives
EP0059554A3 (en) * 1981-02-27 1982-10-20 Beecham Group Plc Beta-lactam antibiotics, a process for their preparation and their use in pharmaceutical compositions
KR900006449B1 (ko) * 1982-08-24 1990-08-31 상꾜 가부시끼가이샤 아제티디논 화합물의 제조방법
US4992542A (en) * 1984-01-24 1991-02-12 Merck & Co., Inc. 2-substituted-6-carbadethiapen-2-em-3-carboxylic acids
JPS60208981A (ja) * 1984-03-15 1985-10-21 Sanraku Inc 新規カルバペナム及びカルバペネム誘導体
EP0277743A1 (en) * 1987-02-02 1988-08-10 Merck & Co. Inc. 2-(heteroaryliumalkyl)phenyl carbapenem antibacterial agents
JPS63290879A (ja) * 1988-04-05 1988-11-28 Sankyo Co Ltd ２−メチルカルバペネム誘導体
EP0466254A1 (en) * 1990-07-11 1992-01-15 Merck & Co. Inc. 2-naphthyl-carbapenems
EP0466253A1 (en) * 1990-07-11 1992-01-15 Merck & Co. Inc. 2-naphthyl-carbapenems
US5409920A (en) * 1990-10-05 1995-04-25 Merck & Co., Inc. 2-(3-pyridyl)-carbapenem antibacterial agents
GB9103034D0 (en) * 1991-02-13 1991-03-27 Fujisawa Pharmaceutical Co Processes for preparing carbapenem derivatives
DE69431919T2 (de) * 1993-10-29 2003-11-13 Smithkline Beecham P.L.C., Brentford 2-(pyrazol-3-yl)carbapenemderivate
US20020147333A1 (en) 1993-10-29 2002-10-10 Smithkline Beecham P.L.C. 2-(pyrazol-3-yl)carbapenem derivatives
US5606051A (en) * 1993-10-29 1997-02-25 Smithkline Beecham P.L.C. 2-(pyrazol-3-yl)carbapenem derivatives
JPH10507185A (ja) * 1994-10-14 1998-07-14 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ２−（イミダゾール−４−イル）カルバペネム誘導体、その中間体および抗菌剤としての使用
EP0823911A1 (en) * 1995-05-03 1998-02-18 Smithkline Beecham Plc Esters of carbapenems
IL118092A0 (en) * 1995-05-03 1996-09-12 Smithkline Beecham Plc Antibacterial compounds their preparation and pharmaceutical compositions containing them
US5814127A (en) * 1996-12-23 1998-09-29 American Air Liquide Inc. Process for recovering CF4 and C2 F6 from a gas
US7468364B2 (en) 2003-04-08 2008-12-23 Dainippon Sumitomo Pharma Co., Ltd. Carbapenem compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
DE2456307A1 (de) * 1974-11-28 1976-08-12 Bayer Ag Beta-lactam-antibiotica, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
AU512383B2 (en) * 1975-11-21 1980-10-09 Merck & Co., Inc. Thinenamycin derivatives
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
US4553983A (en) * 1984-07-31 1985-11-19 Membrane Technology And Research, Inc. Process for recovering organic vapors from air
US4701187A (en) * 1986-11-03 1987-10-20 Air Products And Chemicals, Inc. Process for separating components of a gas stream
EP0343284B1 (de) * 1988-03-25 1993-03-03 OTTO OEKO-TECH GMBH & CO. KG Vorrichtung zur Gewinnung von Kohlenwasserstoffen aus hochkonzentrierten Gasströmen
US4906256A (en) * 1989-03-23 1990-03-06 Membrane Technology & Research, Inc. Membrane process for treatment of fluorinated hydrocarbon-laden gas streams

Also Published As

Publication number Publication date
DE2751624C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-09-08
FR2383959B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-04-02
DE2751624A1 (de) 1978-06-01
SE7713008L (sv) 1978-05-20
FR2371449B1 (fr) 1985-06-21
FR2383960A1 (fr) 1978-10-13
JPS6033836B2 (ja) 1985-08-05
CH640856A5 (en) 1984-01-31
EP0521203A1 (en) 1993-01-07
LU78538A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1978-07-14
JPS5387390A (en) 1978-08-01
GB1593524A (en) 1981-07-15
FR2383960B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-02-26
FR2371449A1 (fr) 1978-06-16
SE436130B (sv) 1984-11-12
FR2383959A1 (fr) 1978-10-13

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
A85 Still pending on 85-01-01
BC A request for examination has been filed
BV The patent application has lapsed