NL7712750A - 1-carba-2-penem-3-carbonzuur en derivaten. - Google Patents

1-carba-2-penem-3-carbonzuur en derivaten.

Info

Publication number
NL7712750A
NL7712750A NL7712750A NL7712750A NL7712750A NL 7712750 A NL7712750 A NL 7712750A NL 7712750 A NL7712750 A NL 7712750A NL 7712750 A NL7712750 A NL 7712750A NL 7712750 A NL7712750 A NL 7712750A
Authority
NL
Netherlands
Prior art keywords
penem
carba
derivatives
carbonic acid
carbonic
Prior art date
Application number
NL7712750A
Other languages
English (en)
Dutch (nl)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL7712750A publication Critical patent/NL7712750A/xx
Priority claimed from AU79443/91A external-priority patent/AU645095B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02Preparation
    • C07D477/04Preparation by forming the ring or condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Of Gases By Adsorption (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
NL7712750A 1976-11-19 1977-11-18 1-carba-2-penem-3-carbonzuur en derivaten. NL7712750A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74336376A 1976-11-19 1976-11-19
US74337076A 1976-11-19 1976-11-19
US84317177A 1977-10-19 1977-10-19
AU79443/91A AU645095B2 (en) 1976-11-19 1991-07-01 Improved process for recovering organic vapors from air

Publications (1)

Publication Number Publication Date
NL7712750A true NL7712750A (nl) 1978-05-23

Family

ID=27423898

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7712750A NL7712750A (nl) 1976-11-19 1977-11-18 1-carba-2-penem-3-carbonzuur en derivaten.

Country Status (9)

Country Link
EP (1) EP0521203A1 (xx)
JP (1) JPS6033836B2 (xx)
CH (1) CH640856A5 (xx)
DE (1) DE2751624A1 (xx)
FR (3) FR2371449B1 (xx)
GB (1) GB1593524A (xx)
LU (1) LU78538A1 (xx)
NL (1) NL7712750A (xx)
SE (1) SE436130B (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
DE2862198D1 (en) * 1977-08-06 1983-04-14 Beecham Group Plc Synthetic beta-lactam compounds, a process for their preparation and compositions containing them
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
EP0030392B1 (en) * 1978-01-19 1984-05-16 Beecham Group Plc Intermediates for use in the preparation of carbapenems
US4272439A (en) * 1978-06-02 1981-06-09 Schering Corporation 6-(Substituted-hydroxymethylene penams)
NZ190994A (en) 1978-07-24 1981-10-19 Merck & Co Inc Z-2-acylamino-3-monosubstituted propenoates
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
ATE15039T1 (de) * 1979-04-27 1985-09-15 Merck & Co Inc Verfahren zur herstellung von 3-(1-hydroxyaethyl)- azetidinonen.
JPS56142260A (en) * 1980-04-09 1981-11-06 Toyama Chem Co Ltd 2-azetidinone and its preparation
CA1179675A (en) * 1981-01-30 1984-12-18 Erwin Gotschi 7-oxo-1-azabicyclo ¬3,2,0| heptene-2-derivatives
EP0059554A3 (en) * 1981-02-27 1982-10-20 Beecham Group Plc Beta-lactam antibiotics, a process for their preparation and their use in pharmaceutical compositions
KR900006449B1 (ko) * 1982-08-24 1990-08-31 상꾜 가부시끼가이샤 아제티디논 화합물의 제조방법
US4992542A (en) * 1984-01-24 1991-02-12 Merck & Co., Inc. 2-substituted-6-carbadethiapen-2-em-3-carboxylic acids
JPS60208981A (ja) * 1984-03-15 1985-10-21 Sanraku Inc 新規カルバペナム及びカルバペネム誘導体
EP0277743A1 (en) * 1987-02-02 1988-08-10 Merck & Co. Inc. 2-(heteroaryliumalkyl)phenyl carbapenem antibacterial agents
JPS63290879A (ja) * 1988-04-05 1988-11-28 Sankyo Co Ltd 2−メチルカルバペネム誘導体
EP0466254A1 (en) * 1990-07-11 1992-01-15 Merck & Co. Inc. 2-naphthyl-carbapenems
EP0466253A1 (en) * 1990-07-11 1992-01-15 Merck & Co. Inc. 2-naphthyl-carbapenems
US5409920A (en) * 1990-10-05 1995-04-25 Merck & Co., Inc. 2-(3-pyridyl)-carbapenem antibacterial agents
GB9103034D0 (en) * 1991-02-13 1991-03-27 Fujisawa Pharmaceutical Co Processes for preparing carbapenem derivatives
US20020147333A1 (en) 1993-10-29 2002-10-10 Smithkline Beecham P.L.C. 2-(pyrazol-3-yl)carbapenem derivatives
US5606051A (en) * 1993-10-29 1997-02-25 Smithkline Beecham P.L.C. 2-(pyrazol-3-yl)carbapenem derivatives
ES2188621T3 (es) * 1993-10-29 2003-07-01 Smithkline Beecham Plc Derivados de 2-(pirazol-3-il)carbapenem.
WO1996011932A1 (en) * 1994-10-14 1996-04-25 Smithkline Beecham Plc 2-(imidazol-4-yl)carbapeneme derivatives, intermediates thereof and use as antibacterials
IL118092A0 (en) * 1995-05-03 1996-09-12 Smithkline Beecham Plc Antibacterial compounds their preparation and pharmaceutical compositions containing them
PL323148A1 (en) * 1995-05-03 1998-03-16 Smithkline Beecham Plc Esters of crabapenemes
US5814127A (en) * 1996-12-23 1998-09-29 American Air Liquide Inc. Process for recovering CF4 and C2 F6 from a gas
EP1612211A4 (en) 2003-04-08 2008-07-02 Dainippon Sumitomo Pharma Co NEW CARBAPENEM COMPOUNDS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
DE2456307A1 (de) * 1974-11-28 1976-08-12 Bayer Ag Beta-lactam-antibiotica, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IL50911A (en) * 1975-11-21 1981-01-30 Merck & Co Inc Substituted n-methylene derivatives of thienamycin
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
US4553983A (en) * 1984-07-31 1985-11-19 Membrane Technology And Research, Inc. Process for recovering organic vapors from air
US4701187A (en) * 1986-11-03 1987-10-20 Air Products And Chemicals, Inc. Process for separating components of a gas stream
DE3878900D1 (de) * 1988-03-25 1993-04-08 Otto Oeko Tech Vorrichtung zur gewinnung von kohlenwasserstoffen aus hochkonzentrierten gasstroemen.
US4906256A (en) * 1989-03-23 1990-03-06 Membrane Technology & Research, Inc. Membrane process for treatment of fluorinated hydrocarbon-laden gas streams

Also Published As

Publication number Publication date
GB1593524A (en) 1981-07-15
DE2751624C2 (xx) 1988-09-08
FR2371449A1 (fr) 1978-06-16
FR2383960B1 (xx) 1982-02-26
EP0521203A1 (en) 1993-01-07
FR2371449B1 (fr) 1985-06-21
CH640856A5 (en) 1984-01-31
SE436130B (sv) 1984-11-12
SE7713008L (sv) 1978-05-20
FR2383960A1 (fr) 1978-10-13
FR2383959A1 (fr) 1978-10-13
DE2751624A1 (de) 1978-06-01
JPS5387390A (en) 1978-08-01
LU78538A1 (xx) 1978-07-14
FR2383959B1 (xx) 1982-04-02
JPS6033836B2 (ja) 1985-08-05

Similar Documents

Publication Publication Date Title
NL7712750A (nl) 1-carba-2-penem-3-carbonzuur en derivaten.
NL7711901A (nl) Benzamidederivaten.
NL7708929A (nl) Cyclohexaanderivaten.
NL7704259A (nl) Luier.
NL7707853A (nl) Luier.
SE7701310L (sv) Polyoxygenerade labdanderivat
NL7704210A (nl) Fenoxy-fenoxypropionzuurderivaten.
NL7606655A (nl) Imidylbenzeendi- en -tricarbonzuurderivaten.
NL7707646A (nl) Polygalactosidosucrosederivaten met comple- ment-remmende activiteit.
NL7705037A (nl) M-fenoxybenzamide-derivaten.
NL7704174A (nl) Nieuwe m-fenylfenoxypropionzuurderivaten en de bereidingswijze daarvan.
NL7709788A (nl) 7-acylamino-8-oxo-3-oxa-1-azabicyclo-(4.2.0.)- octaan-2-carbonzuurderivaten.
FI773946A (fi) Spik
NL7711307A (nl) Fosforcarbonzuurverbindingen en hun bereiding.
NL7808011A (nl) Norbornaan- en norborneen-derivaten.
NL7708730A (nl) Cyclohexaanderivaten.
NL7705896A (nl) Polyprenylcarbonzuurderivaten.
NL7707558A (nl) Fenothiazinederivaten.
SE7704172L (sv) Naftyridinderivat
NL7803725A (nl) 4-alkylthio-2-trifluormethylalkaansulfonaniliden en derivaten daarvan.
NL7708845A (nl) 1-aryloxy-3-aminopropan-2-ol derivaten.
NL7708338A (nl) Acetidinederivaten.
DK324677A (da) Phenoxyeddikesyreester
DK344077A (da) Isoindolderivater
FI773911A (fi) Metoxibenzamidderivat

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
A85 Still pending on 85-01-01
BC A request for examination has been filed
BV The patent application has lapsed