NL7711791A - Chromogene protease-substraten en werkwijze voor de bereiding daarvan. - Google Patents

Chromogene protease-substraten en werkwijze voor de bereiding daarvan.

Info

Publication number
NL7711791A
NL7711791A NL7711791A NL7711791A NL7711791A NL 7711791 A NL7711791 A NL 7711791A NL 7711791 A NL7711791 A NL 7711791A NL 7711791 A NL7711791 A NL 7711791A NL 7711791 A NL7711791 A NL 7711791A
Authority
NL
Netherlands
Prior art keywords
preparation
protease substrates
chromogenic
chromogenic protease
substrates
Prior art date
Application number
NL7711791A
Other languages
English (en)
Other versions
NL178600C (nl
Original Assignee
Kabi Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Ab filed Critical Kabi Ab
Publication of NL7711791A publication Critical patent/NL7711791A/nl
Application granted granted Critical
Publication of NL178600C publication Critical patent/NL178600C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/802—Chromogenic or luminescent peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/28—Bound to a nonpeptide drug, nonpeptide label, nonpeptide carrier, or a nonpeptide resin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
NLAANVRAGE7711791,A 1976-12-01 1977-10-27 Werkwijze voor het bereiden van chromogene protease-substraten. NL178600C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7613463A SE437153B (sv) 1976-12-01 1976-12-01 Specifika kromogena enzymsubstrat for serinproteaser

Publications (2)

Publication Number Publication Date
NL7711791A true NL7711791A (nl) 1978-06-05
NL178600C NL178600C (nl) 1986-04-16

Family

ID=20329625

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7711791,A NL178600C (nl) 1976-12-01 1977-10-27 Werkwijze voor het bereiden van chromogene protease-substraten.

Country Status (23)

Country Link
US (2) US4207232A (nl)
JP (1) JPS5369693A (nl)
AT (1) AT358203B (nl)
AU (1) AU514768B2 (nl)
BE (1) BE861295A (nl)
CA (1) CA1098428A (nl)
CH (1) CH637627A5 (nl)
DD (1) DD136896A5 (nl)
DE (2) DE2753653C2 (nl)
DK (1) DK155333C (nl)
ES (1) ES464117A1 (nl)
FI (1) FI773242A (nl)
FR (1) FR2372798A1 (nl)
GB (1) GB1565154A (nl)
HU (1) HU176983B (nl)
IL (1) IL53187A (nl)
IT (1) IT1092154B (nl)
NL (1) NL178600C (nl)
NO (1) NO774092L (nl)
PL (2) PL109588B1 (nl)
SE (1) SE437153B (nl)
SU (1) SU736889A3 (nl)
ZA (1) ZA776460B (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0016800A1 (en) * 1978-08-03 1980-10-15 American Hospital Supply Corp Determination of proteolytic enzymes in biological fluids and fluorogenic substrates.

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7801373L (sv) * 1978-02-07 1979-08-08 Kabi Ab Lett spjelkbara substrat for kvantifiering av proteaser
US4409140A (en) * 1979-04-23 1983-10-11 Smith Robert E Substrates and method for determining enzymes
CA1161432A (en) * 1980-02-12 1984-01-31 Lars G. Svendsen Tripeptide derivatives and their application in assaying enzymes
DE3164437D1 (en) * 1980-08-25 1984-08-02 Kabivitrum Ab Peptide substrates for determination of protease activity
US4510241A (en) * 1981-09-03 1985-04-09 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
US4406832A (en) * 1981-09-03 1983-09-27 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
US4448715A (en) * 1981-11-02 1984-05-15 University Of Miami Tagged pyroglu-L-Phe-L-Arg derivatives, substrates and assays for kallikrein
DE3211254A1 (de) * 1982-03-26 1983-09-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zum nachweis des vorliegens einer allergie und zum spezifischen nachweis des fuer die allergie verantwortlichen allergens
JPH04501460A (ja) 1988-09-30 1992-03-12 ザ ユニバーシティ オブ バーモント アンド ステイト アグリカルチュラル カレッジ 触媒活性セリンプロテアーゼに関する免疫検定法
WO1995004281A1 (en) * 1993-07-27 1995-02-09 THE UNITED STATES GOVERNMENT, represented by THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION Quantitative method of measuring cancer cell urokinase and metastatic potential
US6297024B1 (en) 1998-10-15 2001-10-02 Cell Activation, Inc. Methods for assessing complement activation
US6235494B1 (en) 1999-02-08 2001-05-22 The Scripps Research Institute Substrates for assessing mannan-binding protein-associated serine protease activity and methods using the substrates
US20050159362A1 (en) * 2003-04-22 2005-07-21 Sircar Jagadish C. Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia
CN1809590A (zh) * 2003-04-22 2006-07-26 阿文尼尔药品公司 治疗高胆固醇血症的反向胆固醇转动的介质
WO2007059511A2 (en) * 2005-11-15 2007-05-24 The Children's Hospital Of Philadelphia Compositions and methods for modulating hemostasis
EP2712423A4 (en) 2011-02-25 2015-06-10 Wellstat Diagnostics Llc ANALYZES FOR DETECTING ENZYMATIC ACTIVITY

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2527932C2 (de) * 1974-07-02 1983-04-21 Pentapharm AG, 4052 Basel Säureadditionssalze von Tripeptidderivaten und deren Verwendung als Substrate zur Bestimmung von Plasmakallikrein
SE407058B (sv) * 1974-12-05 1979-03-12 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
CH622286A5 (nl) * 1975-06-23 1981-03-31 Pentapharm Ag
US4137225A (en) * 1975-07-11 1979-01-30 Ab Kabi Novel chromogenic enzyme substrates
US4061625A (en) * 1975-07-11 1977-12-06 Ab Kabi Novel chromogenic thrombin substrates

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0016800A1 (en) * 1978-08-03 1980-10-15 American Hospital Supply Corp Determination of proteolytic enzymes in biological fluids and fluorogenic substrates.
EP0016800A4 (en) * 1978-08-03 1981-01-08 American Hospital Supply Corp Determination of proteolytic enzymes in biological fluids and fluorogenic substrates.

Also Published As

Publication number Publication date
PL109588B1 (en) 1980-06-30
DE2753653A1 (de) 1978-06-08
DK155333C (da) 1989-09-04
US4207232A (en) 1980-06-10
AU3077177A (en) 1979-05-24
DK155333B (da) 1989-03-28
US4276375A (en) 1981-06-30
BE861295A (fr) 1978-03-16
DD136896A5 (de) 1979-08-01
JPS5369693A (en) 1978-06-21
DE2760116C2 (de) 1985-09-12
FR2372798B1 (nl) 1983-11-10
IT1092154B (it) 1985-07-06
NL178600C (nl) 1986-04-16
CH637627A5 (de) 1983-08-15
HU176983B (hu) 1981-06-28
CA1098428A (en) 1981-03-31
AU514768B2 (en) 1981-02-26
SE7613463L (sv) 1978-06-02
ES464117A1 (es) 1978-09-01
SE437153B (sv) 1985-02-11
DK535377A (da) 1978-06-02
ZA776460B (en) 1978-08-30
DE2753653C2 (de) 1983-07-21
PL110803B1 (en) 1980-08-30
IL53187A (en) 1981-02-27
PL202501A1 (pl) 1978-12-04
NO774092L (no) 1978-06-02
ATA859677A (de) 1980-01-15
IL53187A0 (en) 1977-12-30
FI773242A (fi) 1978-06-02
SU736889A3 (ru) 1980-05-25
JPS578720B2 (nl) 1982-02-17
AT358203B (de) 1980-08-25
FR2372798A1 (fr) 1978-06-30
GB1565154A (en) 1980-04-16

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
TNT Modifications of names of proprietors of patents or applicants of examined patent applications

Owner name: KABIVITRUM AKTIEBOLAG

TNT Modifications of names of proprietors of patents or applicants of examined patent applications

Owner name: KABI PHARMACIA AB

SNR Assignments of patents or rights arising from examined patent applications

Owner name: CHROMOGENIX AB

V1 Lapsed because of non-payment of the annual fee

Effective date: 19970501