NL7703503A - Werkwijze voor de bereiding van nieuwe prostag- landine derivaten. - Google Patents

Werkwijze voor de bereiding van nieuwe prostag- landine derivaten.

Info

Publication number
NL7703503A
NL7703503A NL7703503A NL7703503A NL7703503A NL 7703503 A NL7703503 A NL 7703503A NL 7703503 A NL7703503 A NL 7703503A NL 7703503 A NL7703503 A NL 7703503A NL 7703503 A NL7703503 A NL 7703503A
Authority
NL
Netherlands
Prior art keywords
prostag
landin
derivatives
preparation
new
Prior art date
Application number
NL7703503A
Other languages
English (en)
Dutch (nl)
Original Assignee
Labaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz filed Critical Labaz
Publication of NL7703503A publication Critical patent/NL7703503A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126Acids containing more than four carbon atoms
    • C07C53/128Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
NL7703503A 1976-03-31 1977-03-31 Werkwijze voor de bereiding van nieuwe prostag- landine derivaten. NL7703503A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL49325A IL49325A (en) 1976-03-31 1976-03-31 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
NL7703503A true NL7703503A (nl) 1977-10-04

Family

ID=11048789

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7703503A NL7703503A (nl) 1976-03-31 1977-03-31 Werkwijze voor de bereiding van nieuwe prostag- landine derivaten.

Country Status (18)

Country Link
US (1) US4115401A (ru)
JP (1) JPS52142060A (ru)
BE (1) BE852941A (ru)
CA (1) CA1074804A (ru)
CH (2) CH624101A5 (ru)
DD (1) DD130352A5 (ru)
DE (1) DE2714129A1 (ru)
ES (1) ES457385A1 (ru)
FR (1) FR2346332A1 (ru)
GB (1) GB1574246A (ru)
HU (1) HU178040B (ru)
IL (1) IL49325A (ru)
IT (1) IT1075373B (ru)
NL (1) NL7703503A (ru)
NO (1) NO149428C (ru)
PL (3) PL107544B1 (ru)
SE (1) SE417603B (ru)
SU (3) SU676162A3 (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1117403B (it) * 1978-07-11 1986-02-17 Glaxo Group Ltd Composti prostanoidi e procedimento per produrli
US4320136A (en) * 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
US4530933A (en) * 1982-12-27 1985-07-23 E. I. Du Pont De Nemours And Company 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents
US4456613A (en) * 1982-12-27 1984-06-26 E. I. Du Pont De Nemours And Company 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof
AP2002002555A0 (en) 1999-12-22 2002-06-30 Pfizer Prod Inc EP4 Receptor selective agonists in the treatment of osteoporosis.
CN1476429A (zh) * 2000-11-27 2004-02-18 �Ʒ� 治疗骨质疏松的ep4受体选择性激动剂
BR0211167A (pt) * 2001-07-16 2004-08-10 Hoffmann La Roche Derivados de 2-pirrolidona como agonistas de prostanóides
EP1409455B1 (en) 2001-07-16 2006-01-04 F. Hoffmann-La Roche Ag Prostaglandin analogues-as ep4 receptor agonists
WO2003009872A1 (en) * 2001-07-23 2003-02-06 Ono Pharmaceutical Co., Ltd. Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient
WO2003074483A1 (fr) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif
MXPA04009036A (es) * 2002-03-18 2005-01-25 Pfizer Prod Inc Uso de agonistas del receptor ep4 selectivos para el tratamiento de la insuficiencia hepatica, perdida de permeabilidad del ductus arterioso, glaucoma o hipertension ocular.
JP2006515015A (ja) * 2003-01-10 2006-05-18 エフ.ホフマン−ラ ロシュ アーゲー プロスタグランジンアゴニストとしての2−ピペリドン誘導体
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US20080058375A1 (en) * 2004-01-08 2008-03-06 Elworthy Todd R 2-Piperidone derivatives as prostaglandin antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones

Also Published As

Publication number Publication date
GB1574246A (en) 1980-09-03
PL108289B1 (pl) 1980-03-31
NO149428B (no) 1984-01-09
PL107643B1 (pl) 1980-02-29
IL49325A0 (en) 1976-05-31
NO771134L (no) 1977-10-03
CA1074804A (en) 1980-04-01
FR2346332B1 (ru) 1980-05-09
IL49325A (en) 1979-11-30
FR2346332A1 (fr) 1977-10-28
SU715019A3 (ru) 1980-02-05
JPS52142060A (en) 1977-11-26
PL107544B1 (pl) 1980-02-29
CH628032A5 (fr) 1982-02-15
DD130352A5 (de) 1978-03-22
NO149428C (no) 1984-04-18
SE7703698L (sv) 1977-10-01
US4115401A (en) 1978-09-19
BE852941A (fr) 1977-09-28
ES457385A1 (es) 1978-02-01
IT1075373B (it) 1985-04-22
HU178040B (en) 1982-02-28
SU676162A3 (ru) 1979-07-25
SE417603B (sv) 1981-03-30
DE2714129A1 (de) 1977-10-13
CH624101A5 (ru) 1981-07-15
PL197005A1 (pl) 1978-10-09
SU837321A3 (ru) 1981-06-07

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Legal Events

Date Code Title Description
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: SANOFI SOCIETE ANONYME

BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed