US6048729A
(en)
|
1987-05-01 |
2000-04-11 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
FR2646438B1
(fr)
*
|
1989-03-20 |
2007-11-02 |
Pasteur Institut |
Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration
|
US6689610B1
(en)
|
1989-08-22 |
2004-02-10 |
University Of Utah Research Foundation |
Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
|
DK0452484T3
(da)
*
|
1989-11-06 |
1996-10-14 |
Cell Genesys Inc |
Fremstilling af proteiner ved homolog rekombination
|
US5272071A
(en)
*
|
1989-12-22 |
1993-12-21 |
Applied Research Systems Ars Holding N.V. |
Method for the modification of the expression characteristics of an endogenous gene of a given cell line
|
EP0505500B1
(en)
*
|
1989-12-22 |
1997-07-30 |
Applied Research Systems Ars Holding N.V. |
Endogenous gene expression modification with regulatory element by way of homologous recombination
|
EP0539573A4
(en)
*
|
1991-05-15 |
1993-12-29 |
Cell Genesys, Inc. |
Genomic modifications with homologous dna targeting
|
WO1993004169A1
(en)
*
|
1991-08-20 |
1993-03-04 |
Genpharm International, Inc. |
Gene targeting in animal cells using isogenic dna constructs
|
US6063630A
(en)
*
|
1991-11-05 |
2000-05-16 |
Transkaryotic Therapies, Inc. |
Targeted introduction of DNA into primary or secondary cells and their use for gene therapy
|
US5733761A
(en)
*
|
1991-11-05 |
1998-03-31 |
Transkaryotic Therapies, Inc. |
Protein production and protein delivery
|
US6692737B1
(en)
|
1991-11-05 |
2004-02-17 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
US6270989B1
(en)
|
1991-11-05 |
2001-08-07 |
Transkaryotic Therapies, Inc. |
Protein production and delivery
|
PT101031B
(pt)
*
|
1991-11-05 |
2002-07-31 |
Transkaryotic Therapies Inc |
Processo para o fornecimento de proteinas por terapia genetica
|
US6054288A
(en)
*
|
1991-11-05 |
2000-04-25 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
US5641670A
(en)
*
|
1991-11-05 |
1997-06-24 |
Transkaryotic Therapies, Inc. |
Protein production and protein delivery
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
US6531124B1
(en)
|
1992-07-10 |
2003-03-11 |
Transkaryotic Therapies, Inc. |
In vivo production and delivery of insulinotropin for gene therapy
|
AU5087193A
(en)
*
|
1992-08-21 |
1994-03-15 |
Regents Of The University Of California, The |
Composition and method for altering dna sequences by homologous recombination
|
DE4228162C1
(de)
|
1992-08-25 |
1994-01-13 |
Rajewsky Klaus Dr |
Verfahren zum Ersetzen homologer Genabschnitte aus Säugern in der Keimbahn von nicht-menschlichen Säugern
|
CA2161088A1
(en)
|
1993-04-21 |
1994-10-27 |
Austin Gerard Smith |
Expression of heterologous genes according to a targeted expression profile
|
US5830729A
(en)
|
1996-04-18 |
1998-11-03 |
Institut Pasteur |
I Sce I-induced gene replacement and gene conversion in embryonic stem cells
|
US6924146B1
(en)
*
|
1997-02-21 |
2005-08-02 |
Sigrid Wattler |
Method of constructing vectors for homologous recombination directed mutagenesis
|
ATE296356T1
(de)
|
1997-03-14 |
2005-06-15 |
Biogen Idec Inc |
Methode zur spezifischen integration von genen in säugetierzellen durch homologe rekombination, und vektoren zu deren durchführung
|
DK0975755T3
(da)
|
1997-04-16 |
2007-06-11 |
Millennium Pharm Inc |
CRSP-protein (cysteinrige udskilte proteiner), nukleinsyremolekyler der koder herfor samt anvendelser deraf
|
WO1998048005A1
(en)
|
1997-04-24 |
1998-10-29 |
University Of Washington |
Targeted gene modification by parvoviral vectors
|
AU757930B2
(en)
*
|
1997-12-01 |
2003-03-13 |
Roche Diagnostics Gmbh |
Optimization of cells for endogenous gene activation
|
US6746852B1
(en)
|
1998-05-08 |
2004-06-08 |
Osi Pharmaceuticals, Inc. |
AGS proteins and nucleic acid molecules and uses thereof
|
US6733991B1
(en)
|
1998-05-08 |
2004-05-11 |
Osi Pharmaceuticals, Inc. |
AGS proteins and nucleic acid molecules and uses therefor
|
DE19857609A1
(de)
|
1998-12-14 |
2000-06-15 |
Hannelore Ehrenreich |
Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen
|
AU3382800A
(en)
|
1999-02-26 |
2000-09-14 |
Millennium Pharmaceuticals, Inc. |
Secreted proteins and uses thereof
|
US7291714B1
(en)
|
1999-06-30 |
2007-11-06 |
Millennium Pharmaceuticals, Inc. |
Glycoprotein VI and uses thereof
|
GB9918319D0
(en)
*
|
1999-08-03 |
1999-10-06 |
Smithkline Beecham Biolog |
Vaccine composition
|
EP2360254A1
(en)
|
1999-08-23 |
2011-08-24 |
Dana-Farber Cancer Institute, Inc. |
Assays for screening anti-pd-1 antibodies and uses thereof
|
GB0018876D0
(en)
*
|
2000-08-01 |
2000-09-20 |
Applied Research Systems |
Method of producing polypeptides
|
CA2417432C
(en)
|
2000-09-01 |
2010-11-02 |
The Center For Blood Research, Inc. |
Modified polypeptides stabilized in a desired conformation and methods for producing same
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
US20050144655A1
(en)
|
2000-10-31 |
2005-06-30 |
Economides Aris N. |
Methods of modifying eukaryotic cells
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
NZ526617A
(en)
|
2000-11-28 |
2004-09-24 |
Wyeth Corp |
Expression analysis of KIAA nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer
|
BR0115715A
(pt)
|
2000-11-28 |
2004-02-03 |
Wyeth Corp |
Análise de expressão de ácidos nucleìcos e polipeptìdeos úteis na diagnose e tratamento de câncer da próstata
|
ES2522890T3
(es)
|
2000-12-06 |
2014-11-19 |
Anthrogenesis Corporation |
Método para recolectar células troncales placentarias
|
US7311905B2
(en)
|
2002-02-13 |
2007-12-25 |
Anthrogenesis Corporation |
Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
|
EP1345628B1
(en)
|
2000-12-20 |
2011-04-13 |
F. Hoffmann-La Roche AG |
Conjugates of erythropoietin (epo) with polyethylene glycol (peg)
|
CN100528235C
(zh)
|
2000-12-20 |
2009-08-19 |
霍夫曼-拉罗奇有限公司 |
红细胞生成素共轭物
|
PA8536201A1
(es)
|
2000-12-29 |
2002-08-29 |
Kenneth S Warren Inst Inc |
Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina
|
MX352687B
(es)
|
2001-02-14 |
2017-12-04 |
Anthrogenesis Corp |
Placenta de mamiferos postparto, su uso y celulas madres placentales extraidas de ella.
|
MXPA03007175A
(es)
|
2001-02-14 |
2005-02-14 |
Anthrogenesis Corp |
Placenta de mamiferos postparto, su uso y celulas madres placentales extraidas de ella.
|
US8231878B2
(en)
|
2001-03-20 |
2012-07-31 |
Cosmo Research & Development S.P.A. |
Receptor trem (triggering receptor expressed on myeloid cells) and uses thereof
|
US8981061B2
(en)
|
2001-03-20 |
2015-03-17 |
Novo Nordisk A/S |
Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
|
JP2005508608A
(ja)
|
2001-03-22 |
2005-04-07 |
アボット ゲーエムベーハー ウント カンパニー カーゲー |
問題遺伝子に対して特異的な抗体を発現するトランスジェニック動物及びその使用
|
EP2388590A1
(en)
|
2001-04-02 |
2011-11-23 |
Dana Farber Cancer Institute |
PD-1, a receptor for B7-4, and uses thereof
|
CA2444133A1
(en)
|
2001-04-16 |
2002-10-24 |
Wyeth Holdings Corporation |
Novel streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof
|
FR2824844B1
(fr)
*
|
2001-05-18 |
2003-09-19 |
Genoway |
Procede de clonage par double selection et vecteurs pour ce procede
|
US6949691B2
(en)
*
|
2001-06-15 |
2005-09-27 |
New Century Pharmaceuticals Inc. |
Human albumin animal models for drug evaluation, toxicology and immunogenicity studies
|
US20030211040A1
(en)
|
2001-08-31 |
2003-11-13 |
Paul Greengard |
Phosphodiesterase activity and regulation of phosphodiesterase 1B-mediated signaling in brain
|
AU2002352558A1
(en)
|
2001-11-09 |
2003-05-26 |
Dana-Farber Cancer Institute, Inc. |
Pgc-1beta, a novel pgc-1 homologue and uses therefor
|
NZ579705A
(en)
|
2002-02-13 |
2011-07-29 |
Anthrogenesis Corp |
Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
|
US7153685B2
(en)
|
2002-03-11 |
2006-12-26 |
The Board Of Trustees Of The University Of Illinois |
Tamoxifen and 4-hydroxytamoxifen-activated system for regulated production of proteins in eukaryotic cells
|
EP1485475B2
(en)
*
|
2002-03-15 |
2017-09-20 |
Cellectis |
Hybrid and single chain meganucleases and use thereof
|
US20100151556A1
(en)
*
|
2002-03-15 |
2010-06-17 |
Cellectis |
Hybrid and single chain meganucleases and use thereof
|
WO2009095742A1
(en)
|
2008-01-31 |
2009-08-06 |
Cellectis |
New i-crei derived single-chain meganuclease and uses thereof
|
US7498171B2
(en)
|
2002-04-12 |
2009-03-03 |
Anthrogenesis Corporation |
Modulation of stem and progenitor cell differentiation, assays, and uses thereof
|
EP2801616A1
(en)
|
2002-06-17 |
2014-11-12 |
Thrasos Innovation, Inc. |
Single domain TDF-related compounds and analogs thereof
|
EP2311979A1
(en)
|
2002-08-20 |
2011-04-20 |
Millennium Pharmaceuticals, Inc. |
Compositions, kits and methods for identification, assessment, prevention and therapy of cervical cancer
|
US7459435B2
(en)
|
2002-08-29 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
US7459436B2
(en)
|
2002-11-22 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
CN1717177A
(zh)
|
2002-11-26 |
2006-01-04 |
人类起源公司 |
细胞治疗剂、细胞治疗单元及其用于治疗的方法
|
CA2802143C
(en)
|
2003-01-14 |
2018-06-19 |
Dana-Farber Cancer Institute |
Sparc encoding polynucleotide as a cancer therapy sensitizer
|
EP3202899B1
(en)
|
2003-01-28 |
2020-10-21 |
Cellectis |
Custom-made meganuclease and use thereof
|
US9572840B2
(en)
|
2003-06-27 |
2017-02-21 |
DePuy Synthes Products, Inc. |
Regeneration and repair of neural tissue using postpartum-derived cells
|
US7875272B2
(en)
|
2003-06-27 |
2011-01-25 |
Ethicon, Incorporated |
Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
|
PL2338982T3
(pl)
|
2003-06-27 |
2016-01-29 |
Depuy Synthes Products Inc |
Komórki poporodowe pochodzące z tkanek pępowinowych i sposoby ich wytwarzania i zastosowania
|
US8790637B2
(en)
|
2003-06-27 |
2014-07-29 |
DePuy Synthes Products, LLC |
Repair and regeneration of ocular tissue using postpartum-derived cells
|
US9592258B2
(en)
|
2003-06-27 |
2017-03-14 |
DePuy Synthes Products, Inc. |
Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
|
US7888121B2
(en)
|
2003-08-08 |
2011-02-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
US11311574B2
(en)
|
2003-08-08 |
2022-04-26 |
Sangamo Therapeutics, Inc. |
Methods and compositions for targeted cleavage and recombination
|
US8409861B2
(en)
|
2003-08-08 |
2013-04-02 |
Sangamo Biosciences, Inc. |
Targeted deletion of cellular DNA sequences
|
EP1651660B1
(en)
|
2003-08-08 |
2018-01-24 |
Sangamo Therapeutics, Inc. |
Methods and compositions for targeted cleavage and recombination
|
CN1897959A
(zh)
|
2003-09-29 |
2007-01-17 |
沃伦药品公司 |
用于治疗和预防脓毒病和粘连形成的组织保护细胞因子
|
EP2051077A3
(en)
|
2003-10-07 |
2009-05-27 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
US7951532B2
(en)
|
2003-11-12 |
2011-05-31 |
Children's Hospital Medical Center |
Method of screening a midkine modulating agent
|
US10793873B2
(en)
|
2003-11-21 |
2020-10-06 |
Revivicor, Inc. |
Use of interfering RNA in the production of transgenic animals
|
US7371539B2
(en)
|
2003-12-03 |
2008-05-13 |
President And Fellows Of Harvard College |
Targeted polypeptide degradation
|
CA2549486C
(en)
*
|
2003-12-19 |
2015-04-14 |
F. Hoffmann-La Roche Ag |
Use of erythropoietin in the treatment of disturbances of iron distribution in chronic inflammatory intestinal diseases
|
EP2319526A1
(en)
|
2004-06-17 |
2011-05-11 |
Thrasos Therapeutics, Inc. |
Tdf-related compounds and analogs thereof
|
US7288385B2
(en)
|
2004-06-25 |
2007-10-30 |
The Salk Institute For Biological Studies |
Increasing life span by modulation of Smek
|
GB0426146D0
(en)
|
2004-11-29 |
2004-12-29 |
Bioxell Spa |
Therapeutic peptides and method
|
PT1835924E
(pt)
|
2004-12-23 |
2013-11-19 |
Ethicon Inc |
Tratamento da doença de parkinson e desordens relacionadas usando células derivadas do pós-parto
|
US8293477B2
(en)
|
2005-04-15 |
2012-10-23 |
Cornell University |
Methods for modulating bone formation and mineralization by modulating KRC activity
|
KR20080033455A
(ko)
|
2005-07-26 |
2008-04-16 |
상가모 바이오사이언스 인코포레이티드 |
외래 핵산 서열의 표적화된 통합 및 발현
|
EP3031470A3
(en)
|
2005-09-09 |
2016-08-10 |
The Johns Hopkins University |
Manipulation of regulatory t cell and dc function by targeting neuritin gene using antibodies, agonists and antagonists
|
EP1926459B1
(en)
|
2005-09-19 |
2015-01-07 |
Histogenics Corporation |
Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
|
PL2497780T3
(pl)
|
2005-09-20 |
2015-09-30 |
Thrasos Innovation Inc |
Związki pokrewne TDF oraz ich analogi
|
US20070072795A1
(en)
*
|
2005-09-28 |
2007-03-29 |
Anton Haselbeck |
Treatment of neurodegenerative disorders
|
US9388382B2
(en)
|
2005-10-05 |
2016-07-12 |
The Board Of Trustees Of The University Of Illinois |
Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells
|
SI1957633T1
(sl)
|
2005-10-13 |
2014-04-30 |
Anthrogenesis Corporation |
Imunomodulacija z uporabo matičnih celic iz placente
|
WO2009134714A2
(en)
*
|
2008-04-28 |
2009-11-05 |
Precision Biosciences, Inc. |
Fusion molecules of rationally-designed dna-binding proteins and effector domains
|
WO2007060495A1
(en)
*
|
2005-10-25 |
2007-05-31 |
Cellectis |
I-crei homing endonuclease variants having novel cleavage specificity and use thereof
|
CN101374946B
(zh)
|
2005-12-16 |
2017-07-18 |
伊西康公司 |
用于在组织相容性不匹配的移植中抑制有害的免疫反应的组合物和方法
|
US9125906B2
(en)
|
2005-12-28 |
2015-09-08 |
DePuy Synthes Products, Inc. |
Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
|
CN103525758B
(zh)
|
2005-12-29 |
2018-02-13 |
人类起源公司 |
胎盘干细胞群
|
DE102006004008A1
(de)
|
2006-01-27 |
2007-08-02 |
Hannelore Prof. Dr. Dr. Ehrenreich |
Verfahren zur Behandlung und/oder Prophylaxe von Multipler Sklerose, sowie Verwendung von Erythropoietin zur Herstellung eines Arzneimittels zur intermittierenden Behandlung und/oder intermittierenden Prophylaxe von Multipler Sklerose
|
LT2004683T
(lt)
|
2006-03-24 |
2016-10-10 |
Biogen Hemophilia Inc. |
Pc5, kaip faktoriaus ix pro-peptidą apdorojantis fermentas
|
GB0607063D0
(en)
|
2006-04-07 |
2006-05-17 |
Cellcentric Ltd |
Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
|
US7875453B2
(en)
|
2006-06-14 |
2011-01-25 |
Bioe Llc |
Differentiation of multi-lineage progenitor cells to hepatocytes
|
PL2054074T3
(pl)
|
2006-08-04 |
2015-03-31 |
Prolong Pharmaceuticals Llc |
Zmodyfikowana erytropoetyna
|
CN105296527B
(zh)
*
|
2006-08-11 |
2020-11-27 |
陶氏益农公司 |
锌指核酸酶介导的同源重组
|
US9580515B2
(en)
|
2006-08-21 |
2017-02-28 |
Zensun (Shanghai) Science & Technology, Co., Ltd. |
Neukinase, a downstream protein of neuregulin
|
ES2432395T3
(es)
|
2006-10-12 |
2013-12-03 |
Ethicon, Inc. |
Células derivadas de riñon y metodo de uso en la reparación y regeneración tisular
|
CA2666789C
(en)
|
2006-10-18 |
2016-11-22 |
Yong Zhao |
Embryonic-like stem cells derived from adult human peripheral blood and methods of use
|
WO2008100498A2
(en)
|
2007-02-12 |
2008-08-21 |
Anthrogenesis Corporation |
Treatment of inflammatory diseases using placental stem cells
|
SI2602323T1
(en)
|
2007-06-01 |
2018-05-31 |
Open Monoclonal Technology, Inc. |
Compositions and procedures for inhibiting endogenous immunoglobin gene and the formation of transgenic human idiopathic antibodies
|
EP2167666A2
(en)
|
2007-06-29 |
2010-03-31 |
Pioneer Hi-Bred International Inc. |
Methods for altering the genome of a monocot plant cell
|
AR067536A1
(es)
|
2007-07-17 |
2009-10-14 |
Hoffmann La Roche |
Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea
|
CL2008002053A1
(es)
|
2007-07-17 |
2009-05-22 |
Hoffmann La Roche |
Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion.
|
WO2009010107A1
(en)
|
2007-07-19 |
2009-01-22 |
Hannelore Ehrenreich |
Use of epo receptor activation or stimulation for the improvement of the edss score in patients with multiple sclerosis
|
US9200253B1
(en)
|
2007-08-06 |
2015-12-01 |
Anthrogenesis Corporation |
Method of producing erythrocytes
|
AU2008307633C1
(en)
|
2007-09-28 |
2015-04-30 |
Celularity Inc. |
Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
|
EP2214708A4
(en)
|
2007-10-26 |
2011-01-12 |
Centocor Ortho Biotech Inc |
VECTORS, HOST CELLS, METHODS OF PRODUCTION AND USES
|
CA2708776A1
(en)
*
|
2007-12-10 |
2009-06-18 |
Aliva Biopharmaceuticals, Inc. |
Methods for sequential replacement of targeted region by homologous recombination
|
US8566040B2
(en)
|
2008-02-12 |
2013-10-22 |
Ramot At Tel-Aviv University Ltd |
Method for searching for homing endonucleases, their genes and their targets
|
WO2009114321A2
(en)
|
2008-03-11 |
2009-09-17 |
Precision Biosciencs, Inc. |
Rationally-designed meganucleases for maize genome engineering
|
AU2009238629C1
(en)
*
|
2008-04-14 |
2015-04-30 |
Sangamo Therapeutics, Inc. |
Linear donor constructs for targeted integration
|
CA2739038C
(en)
|
2008-09-30 |
2020-04-28 |
Ablexis, Llc |
Non-human mammals for the production of chimeric antibodies
|
RU2562154C2
(ru)
|
2008-11-19 |
2015-09-10 |
Антродженезис Корпорейшн |
Амниотические адгезивные клетки
|
US10179900B2
(en)
|
2008-12-19 |
2019-01-15 |
DePuy Synthes Products, Inc. |
Conditioned media and methods of making a conditioned media
|
CN107028983A
(zh)
|
2008-12-19 |
2017-08-11 |
德普伊新特斯产品有限责任公司 |
肺部疾病和病症的治疗
|
US9181315B2
(en)
|
2009-01-08 |
2015-11-10 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for induced brown fat differentiation
|
US9493545B2
(en)
|
2009-02-11 |
2016-11-15 |
Albumedix A/S |
Albumin variants and conjugates
|
CA2756600C
(en)
|
2009-03-26 |
2019-08-20 |
Advanced Technologies And Regenerative Medicine, Llc |
Human umbilical cord tissue cells as therapy for alzheimer's disease
|
US8772008B2
(en)
|
2009-05-18 |
2014-07-08 |
Sangamo Biosciences, Inc. |
Methods and compositions for increasing nuclease activity
|
WO2010141606A2
(en)
*
|
2009-06-02 |
2010-12-09 |
Davinci Biosciences Llc |
Human gonadal stem cells
|
EP2261242A1
(en)
|
2009-06-10 |
2010-12-15 |
Universite Catholique De Louvain |
Aspartate-N-acetyltransferase enzyme, diagnostic method and therapeutic method
|
WO2011017315A2
(en)
*
|
2009-08-03 |
2011-02-10 |
Recombinetics, Inc. |
Methods and compositions for targeted gene modification
|
US20110064717A1
(en)
*
|
2009-08-20 |
2011-03-17 |
Ramot At Tel-Aviv University Ltd. |
Homing endonuclease genes and their targets
|
CA3049393C
(en)
|
2009-09-23 |
2020-12-29 |
Restem Llc |
Umbilical cord lining stem cells and methods and material for isolating and culturing same
|
US8323972B2
(en)
|
2009-09-30 |
2012-12-04 |
Advanced Technologies And Regenerative Medicine, Llc |
Mammary artery derived cells and methods of use in tissue repair and regeneration
|
US8889413B2
(en)
|
2009-09-30 |
2014-11-18 |
DePuy Synthes Products, LLC |
Mammary artery derived cells and methods of use in tissue repair and regeneration
|
US9745589B2
(en)
|
2010-01-14 |
2017-08-29 |
Cornell University |
Methods for modulating skeletal remodeling and patterning by modulating SHN2 activity, SHN3 activity, or SHN2 and SHN3 activity in combination
|
EP2526424A2
(en)
|
2010-01-22 |
2012-11-28 |
Dana-Farber Cancer Institute, Inc. |
Compositions,kits, and methods for identification, assessment, prevention, and therapy of metabolic disorders
|
CA2787992A1
(en)
|
2010-01-26 |
2011-08-04 |
Anthrogenesis Corporation |
Treatment of bone-related cancers using placental stem cells
|
TWI518325B
(zh)
|
2010-02-04 |
2016-01-21 |
自治醫科大學 |
對alk抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
|
EP2534163B1
(en)
|
2010-02-09 |
2015-11-04 |
Sangamo BioSciences, Inc. |
Targeted genomic modification with partially single-stranded donor molecules
|
EP4345163A3
(en)
|
2010-03-31 |
2024-06-19 |
Ablexis, LLC |
Genetic engineering of non-human animals for the production of chimeric antibodies
|
WO2011127117A1
(en)
|
2010-04-07 |
2011-10-13 |
Anthrogenesis Corporation |
Angiogenesis using placental stem cells
|
US8383793B2
(en)
|
2010-04-15 |
2013-02-26 |
St. Jude Children's Research Hospital |
Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
|
US20130189759A1
(en)
|
2010-07-07 |
2013-07-25 |
Cellectis |
Meganucleases variants cleaving a dna target sequence in the nanog gene and uses thereof
|
KR20210063457A
(ko)
|
2010-07-13 |
2021-06-01 |
안트로제네시스 코포레이션 |
천연 킬러 세포의 생성 방법
|
WO2012010976A2
(en)
|
2010-07-15 |
2012-01-26 |
Cellectis |
Meganuclease variants cleaving a dna target sequence in the tert gene and uses thereof
|
PL2616101T3
(pl)
|
2010-09-14 |
2015-01-30 |
Hoffmann La Roche |
Sposób oczyszczania pegylowanej erytropoetyny
|
WO2012048213A1
(en)
|
2010-10-08 |
2012-04-12 |
Regents Of The University Of Minnesota |
A method to increase gene targeting frequency
|
EP2658557A1
(en)
|
2010-12-31 |
2013-11-06 |
Anthrogenesis Corporation |
Enhancement of placental stem cell potency using modulatory rna molecules
|
EP3443968A1
(en)
|
2011-06-01 |
2019-02-20 |
Celularity, Inc. |
Treatment of pain using placental stem cells
|
WO2013039996A1
(en)
|
2011-09-13 |
2013-03-21 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for brown fat induction and activity using fndc5
|
WO2013053076A1
(en)
|
2011-10-10 |
2013-04-18 |
Zensun (Shanghai)Science & Technology Limited |
Compositions and methods for treating heart failure
|
GB2496375A
(en)
|
2011-10-28 |
2013-05-15 |
Kymab Ltd |
A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
|
GB201122047D0
(en)
|
2011-12-21 |
2012-02-01 |
Kymab Ltd |
Transgenic animals
|
EP2794854B1
(en)
|
2011-12-23 |
2018-06-20 |
DePuy Synthes Products, Inc. |
Detection of human umbilical cord tissue-derived cells
|
RS56593B1
(sr)
|
2012-02-15 |
2018-02-28 |
Novo Nordisk As |
Antitela koja vezuju i blokiraju aktivirajući receptor eksprimiran na mijeloidnim ćelijama-1 (trem-1)
|
PL2814842T3
(pl)
|
2012-02-15 |
2018-12-31 |
Novo Nordisk A/S |
Przeciwciała wiążące białko 1 rozpoznające peptydoglikan
|
US9550830B2
(en)
|
2012-02-15 |
2017-01-24 |
Novo Nordisk A/S |
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
|
EP2711428A1
(en)
|
2012-09-21 |
2014-03-26 |
Lonza Biologics plc. |
Site-specific integration
|
TR201900694T4
(tr)
|
2012-08-23 |
2019-02-21 |
Agensys Inc |
158p1d7 proteinlerine bağlanan antikor ilaç konjugatları (adc).
|
IN2015DN04148A
(nl)
|
2012-11-16 |
2015-10-16 |
Total Marketing Services |
|
WO2014102688A1
(en)
|
2012-12-27 |
2014-07-03 |
Cellectis |
New design matrix for improvement of homology-directed gene targeting
|
EP3622960A1
(en)
|
2013-02-05 |
2020-03-18 |
Celularity, Inc. |
Natural killer cells from placenta
|
US10066001B2
(en)
|
2013-03-15 |
2018-09-04 |
Apotex Inc. |
Enhanced liquid formulation stability of erythropoietin alpha through purification processing
|
UA118198C2
(uk)
|
2013-08-01 |
2018-12-10 |
Ейдженсіс, Інк. |
Кон'югат антитіло-лікарський засіб, який зв'язується з білком cd37
|
GB201407852D0
(en)
|
2014-05-02 |
2014-06-18 |
Iontas Ltd |
Preparation of libraries od protein variants expressed in eukaryotic cells and use for selecting binding molecules
|
JP6738316B2
(ja)
|
2014-07-17 |
2020-08-12 |
ノヴォ ノルディスク アクティーゼルスカブ |
粘度を低下させるためのtrem−1抗体の部位特異的変異誘発
|
EP3940057A1
(en)
|
2014-09-09 |
2022-01-19 |
Lumen Bioscience, Inc. |
Targeted mutagenesis in spirulina
|
US10077420B2
(en)
|
2014-12-02 |
2018-09-18 |
Histogenics Corporation |
Cell and tissue culture container
|
CA2978631C
(en)
|
2015-03-09 |
2023-06-27 |
Agensys, Inc. |
Antibody drug conjugates (adc) that bind to flt3 proteins
|
WO2016166268A1
(en)
|
2015-04-17 |
2016-10-20 |
Cellectis |
Engineering animal or plant genome using dna-guided argonaute interference systems (dais) from mesophilic prokaryotes
|
EP3091076A1
(en)
|
2015-05-07 |
2016-11-09 |
Limagrain Europe |
Polynucleotide responsible of haploid induction in maize plants and related processes
|
EP3368157B1
(en)
|
2015-10-29 |
2022-06-29 |
Dana-Farber Cancer Institute, Inc. |
Methods for identification, assessment, prevention, and treatment of metabolic disorders using pm20d1 and n-lipidated amino acids
|
US10584363B2
(en)
|
2016-06-03 |
2020-03-10 |
Takara Bio Usa, Inc. |
Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same
|
PL3484911T3
(pl)
|
2016-07-15 |
2021-03-08 |
F. Hoffmann-La Roche Ag |
Sposób oczyszczania PEGylowanej erytropoetyny
|
WO2018073391A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Targeted gene insertion for improved immune cells therapy
|
CN111511903A
(zh)
|
2017-10-19 |
2020-08-07 |
塞勒克提斯公司 |
用于改善的免疫细胞疗法的nk抑制剂基因的靶向基因整合
|
HRP20220388T1
(hr)
|
2017-12-29 |
2022-05-27 |
F. Hoffmann - La Roche Ag |
Postupak za dobivanje pegiliranog proteinskog pripravka
|
US20200323993A1
(en)
|
2017-12-29 |
2020-10-15 |
Hoffmann-La Roche Inc. |
Process for providing pegylated protein composition
|
JP7410860B2
(ja)
|
2017-12-29 |
2024-01-10 |
エフ. ホフマン-ラ ロシュ アーゲー |
Peg化タンパク質組成物を提供するための方法
|
EP3774902A1
(en)
|
2018-04-02 |
2021-02-17 |
Bristol-Myers Squibb Company |
Anti-trem-1 antibodies and uses thereof
|
EP3955957A1
(en)
|
2019-04-15 |
2022-02-23 |
Qwixel Therapeutics LLC |
Fusion protein composition(s) comprising targeted masked type i interferons (ifna and ifnb) and an antibody against tumor antigen, for use in the treatment of cancer
|
AU2020357550A1
(en)
|
2019-10-04 |
2022-05-05 |
Tae Life Sciences, Llc |
Antibody compositions comprising Fc mutations and site-specific conjugation properties
|
JP2023543829A
(ja)
|
2020-09-28 |
2023-10-18 |
ヴェスタロン・コーポレーション |
害虫制御のためのミュー-ジゲトキシン-Dc1aバリアントポリペプチド
|
US12006550B2
(en)
|
2020-10-12 |
2024-06-11 |
University Of South Carolina |
Targeting treatment for ADAM30 in pathological cells
|
WO2022159414A1
(en)
|
2021-01-22 |
2022-07-28 |
University Of Rochester |
Erythropoietin for gastroinfestinal dysfunction
|
WO2022235929A1
(en)
|
2021-05-05 |
2022-11-10 |
Radius Pharmaceuticals, Inc. |
Animal model having homologous recombination of mouse pth1 receptor
|
IL308959A
(en)
|
2021-06-18 |
2024-01-01 |
Nammi Therapeutics Inc |
Fusion protein composition(s) containing masked type I interferons (IFNalpha and IFNbeta) for use in cancer therapy and methods thereof
|
WO2023122805A1
(en)
|
2021-12-20 |
2023-06-29 |
Vestaron Corporation |
Sorbitol driven selection pressure method
|
WO2024026406A2
(en)
|
2022-07-29 |
2024-02-01 |
Vestaron Corporation |
Next Generation ACTX Peptides
|
EP4360451A1
(en)
|
2022-10-25 |
2024-05-01 |
Limagrain Europe |
Mutants for haploid induction
|
WO2024091824A1
(en)
|
2022-10-26 |
2024-05-02 |
Ada Forsyth Institute, Inc. |
Differentiation and reprogramming of chondrocyte
|