NL195028C - Cyclosporinebevattend farmaceutisch preparaat. - Google Patents

Cyclosporinebevattend farmaceutisch preparaat. Download PDF

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Publication number
NL195028C
NL195028C NL9000299A NL9000299A NL195028C NL 195028 C NL195028 C NL 195028C NL 9000299 A NL9000299 A NL 9000299A NL 9000299 A NL9000299 A NL 9000299A NL 195028 C NL195028 C NL 195028C
Authority
NL
Netherlands
Prior art keywords
administration
cyclosporin
preparation
ciclosporin
blood
Prior art date
Application number
NL9000299A
Other languages
English (en)
Dutch (nl)
Other versions
NL9000299A (nl
NL195028B (nl
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898902901A external-priority patent/GB8902901D0/en
Priority claimed from GB898902898A external-priority patent/GB8902898D0/en
Priority claimed from GB898903147A external-priority patent/GB8903147D0/en
Priority claimed from GB898903663A external-priority patent/GB8903663D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NL9000299A publication Critical patent/NL9000299A/nl
Publication of NL195028B publication Critical patent/NL195028B/nl
Application granted granted Critical
Publication of NL195028C publication Critical patent/NL195028C/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL9000299A 1989-02-09 1990-02-08 Cyclosporinebevattend farmaceutisch preparaat. NL195028C (nl)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB8902901 1989-02-09
GB8902898 1989-02-09
GB898902901A GB8902901D0 (en) 1989-02-09 1989-02-09 Improvements in or relating to organic compounds
GB898902898A GB8902898D0 (en) 1989-02-09 1989-02-09 Improvements in or relating to organic compounds
GB898903147A GB8903147D0 (en) 1989-02-13 1989-02-13 Improvements in or relating to organic compounds
GB8903147 1989-02-13
GB8903663 1989-02-17
GB898903663A GB8903663D0 (en) 1989-02-17 1989-02-17 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
NL9000299A NL9000299A (nl) 1990-09-03
NL195028B NL195028B (nl) 2003-08-01
NL195028C true NL195028C (nl) 2003-12-02

Family

ID=27450262

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9000299A NL195028C (nl) 1989-02-09 1990-02-08 Cyclosporinebevattend farmaceutisch preparaat.

Country Status (25)

Country Link
JP (3) JP3484190B2 (de)
KR (1) KR0170769B1 (de)
AT (1) AT404552B (de)
AU (1) AU630413B2 (de)
BE (1) BE1003009A5 (de)
CA (1) CA2009533C (de)
CH (1) CH679277A5 (de)
CY (1) CY1903A (de)
DE (1) DE4003844B4 (de)
DK (1) DK176209B1 (de)
ES (1) ES2021942A6 (de)
FI (1) FI97524C (de)
FR (1) FR2642650B1 (de)
GB (1) GB2230440B (de)
HK (1) HK37296A (de)
HU (1) HU213394B (de)
IT (1) IT1240758B (de)
LU (1) LU87675A1 (de)
MY (1) MY107377A (de)
NL (1) NL195028C (de)
NO (1) NO301576B1 (de)
NZ (1) NZ232401A (de)
PH (1) PH30917A (de)
PT (1) PT93079B (de)
SE (1) SE511398C2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
HU208491B (en) * 1990-11-27 1993-11-29 Gyogyszerkutato Intezet Process for producing oral pharmaceutical composition containing cyclosporin
MX9201782A (es) † 1991-04-19 1992-10-01 Sandoz Ag Particulas de sustancias biologicamente activas, sustancialmente insolubles en agua, proceso para su produccion y composicion farmaceutica que las contiene.
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
SG45449A1 (en) 1992-05-13 1998-01-16 Sandoz Ltd Ophthalmic compositions
US5759566A (en) * 1992-07-28 1998-06-02 Poli Industria Chimica Spa Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents
DK0589843T3 (da) 1992-09-25 2002-04-02 Novartis Ag Cyclosporinholdige farmaceutiske præparater
DE4412201A1 (de) * 1993-04-20 1994-11-10 Rentschler Arzneimittel Neue pharmazeutische Zubereitungen zur oralen Verabreichung enthaltend Cyclosporin
ATE218878T1 (de) * 1993-04-20 2002-06-15 Novartis Erfind Verwalt Gmbh Neue pharmazeutische zubereitungen zur oralen verabreichung enthaltend cyclosporin
DE4340781C3 (de) * 1993-11-30 2000-01-27 Novartis Ag Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung
KR0146671B1 (ko) * 1994-02-25 1998-08-17 김충환 사이클로스포린-함유 분말 조성물
ES2177652T3 (es) 1994-11-03 2002-12-16 Novartis Ag Nuevas formas de preparacion de ciclosporina para la aplicacion oral con composicion simple y alta biodisponibilidad, y procedimiento para su obtencion.
US5679566A (en) * 1995-01-20 1997-10-21 University Of Massachusetts Medical Center Yeast NMD2 gene
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
US5798333A (en) * 1996-09-17 1998-08-25 Sherman; Bernard C. Water-soluble concentrates containing cyclosporins
AU762247B2 (en) * 1997-01-30 2003-06-19 Novartis Ag Oil-free pharmaceutical compositions containing cyclosporin A
KR20050084502A (ko) * 1997-01-30 2005-08-26 노파르티스 아게 오일을 함유하지 않은 사이클로스포린 a 함유 제약 조성물
KR100966245B1 (ko) * 1997-03-12 2010-06-28 아보트 러보러터리즈 사이클로스포린 투여용 친수성 2원 시스템
NZ328751A (en) * 1997-09-16 1999-01-28 Bernard Charles Sherman Solid medicament containing an anionic surfactant and cyclosporin
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
EP2116228A1 (de) 2001-10-19 2009-11-11 Isotechnika Inc. Neuartige Cyclosporinanalog-Mikroemulsionspräkonzentrate
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
JP4521554B2 (ja) * 2004-03-31 2010-08-11 マイラン製薬株式会社 シクロスポリン製剤
US8333989B2 (en) * 2005-10-26 2012-12-18 Banner Pharmacaps, Inc. Hydrophilic vehicle-based dual controlled release matrix system
AU2007230716B2 (en) 2006-03-28 2012-05-03 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
US7495024B2 (en) 2006-08-07 2009-02-24 Via Pharmaceuticals, Inc. Phenylalkyl N-hydroxyureas for combating atherosclerotic plaque
DE102008059201A1 (de) * 2008-11-27 2010-06-02 GÖPFERICH, Achim, Prof. Dr. In situ präzipitierende Arzneistofflösungen
KR102146704B1 (ko) 2018-04-13 2020-08-21 가천대학교 산학협력단 사이클로스포린 A (CsA) 경피 및 피내 약물전달용 마이크로구조체
KR20240070705A (ko) * 2021-10-13 2024-05-21 추가이 세이야쿠 가부시키가이샤 펩타이드 화합물 및 계면활성제를 포함하는 조성물
KR20250002095A (ko) * 2022-05-02 2025-01-07 추가이 세이야쿠 가부시키가이샤 계면활성제와 병용하기 위한 펩타이드 화합물을 포함하는 조성물

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE445174B (sv) * 1978-03-07 1986-06-09 Sandoz Ag Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans
JPS61280435A (ja) * 1985-04-04 1986-12-11 Kanji Takada サイクロスポリン類のリンパ指向性製剤
NL8600050A (nl) * 1986-01-13 1987-08-03 Sanico Nv Farmaceutisch preparaat met vertraagde afgifte van het werkzame bestanddeel en werkwijze voor de bereiding er van.
GB8602372D0 (en) * 1986-01-31 1986-03-05 Sandoz Ltd Organic compounds
CA1290249C (en) * 1986-04-09 1991-10-08 Cetus Corporation COMBINATION THERAPY USING INTERLEUKIN-2 AND/OR INTERFERON-.beta. AND TUMOR NECROSIS FACTOR
EP0267615A3 (de) * 1986-11-13 1989-05-03 Sloan-Kettering Institute For Cancer Research Zusammensetzungen und Methoden zur Behandlung von Krebs unter Benutzung von monoklonalen Antikörpern gegen GD3 Ganglioside mit IL-2
ES2059558T3 (es) * 1987-06-17 1994-11-16 Sandoz Ag Ciclosporins y su uso como productos farmaceuticos.
JP2536876B2 (ja) * 1987-07-31 1996-09-25 寛治 高田 シクロスポリンの溶解性粉末状製剤
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
HU205010B (en) * 1987-09-15 1992-03-30 Sandoz Ag Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity
DE3830494B4 (de) * 1987-09-15 2006-05-18 Novartis Ag Wasserlösliche Monoester als Solubilisatoren für pharmakologische Wirkstoffe und pharmazeutische Hilfsstoffe
JP2792862B2 (ja) * 1988-07-30 1998-09-03 寛治 高田 経口腸溶製剤
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
JPH1038029A (ja) * 1996-07-26 1998-02-13 Ebara Corp 制振機能付き円板状構造物
JPH10280435A (ja) * 1997-04-03 1998-10-20 Sekisui Chem Co Ltd 地下室の構築方法

Also Published As

Publication number Publication date
CA2009533C (en) 2002-11-12
MY107377A (en) 1995-11-30
IT9047609A0 (it) 1990-02-08
JP2006001947A (ja) 2006-01-05
SE9000441D0 (sv) 1990-02-07
DE4003844A1 (de) 1990-08-16
HU213394B (en) 1997-06-30
NO900577L (no) 1990-08-10
NO900577D0 (no) 1990-02-07
PT93079A (pt) 1990-08-31
IT1240758B (it) 1993-12-17
JP4073641B2 (ja) 2008-04-09
SE511398C2 (sv) 1999-09-20
SE9000441L (sv) 1991-08-08
FR2642650B1 (fr) 1994-12-09
JPH02235817A (ja) 1990-09-18
AU4925290A (en) 1990-08-16
AU630413B2 (en) 1992-10-29
JP3484190B2 (ja) 2004-01-06
FI97524B (fi) 1996-09-30
GB9002504D0 (en) 1990-04-04
PH30917A (en) 1997-12-23
FI97524C (fi) 1997-01-10
FI900604A0 (fi) 1990-02-07
ES2021942A6 (es) 1991-11-16
LU87675A1 (fr) 1991-10-08
CY1903A (en) 1996-11-22
GB2230440B (en) 1993-05-19
JP2001302538A (ja) 2001-10-31
CA2009533A1 (en) 1990-08-09
FR2642650A1 (fr) 1990-08-10
BE1003009A5 (fr) 1991-10-22
DK32790A (da) 1990-08-10
KR900012625A (ko) 1990-09-01
NO301576B1 (no) 1997-11-17
DE4003844B4 (de) 2007-09-20
AT404552B (de) 1998-12-28
ATA27290A (de) 1998-05-15
KR0170769B1 (ko) 1999-02-01
IT9047609A1 (it) 1991-08-08
GB2230440A (en) 1990-10-24
NL9000299A (nl) 1990-09-03
DK176209B1 (da) 2007-02-05
NL195028B (nl) 2003-08-01
HU900701D0 (en) 1990-04-28
HK37296A (en) 1996-03-15
DK32790D0 (da) 1990-02-07
CH679277A5 (de) 1992-01-31
PT93079B (pt) 1996-04-30
NZ232401A (en) 1992-10-28

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Effective date: 20100208