NL194203C - 1,4-dihydropyridineverbindingen en farmaceutisch preparaat dat ÚÚn of meer van deze bevat. - Google Patents
1,4-dihydropyridineverbindingen en farmaceutisch preparaat dat ÚÚn of meer van deze bevat. Download PDFInfo
- Publication number
- NL194203C NL194203C NL8204014A NL8204014A NL194203C NL 194203 C NL194203 C NL 194203C NL 8204014 A NL8204014 A NL 8204014A NL 8204014 A NL8204014 A NL 8204014A NL 194203 C NL194203 C NL 194203C
- Authority
- NL
- Netherlands
- Prior art keywords
- dihydropyridine
- dimethyl
- compounds
- dicarboxylate
- nitrophenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16696381A JPS5867668A (ja) | 1981-10-19 | 1981-10-19 | １，４−ジヒドロピリジン誘導体 |
| JP16696381 | 1981-10-19 | ||
| JP259782A JPS58121288A (ja) | 1982-01-11 | 1982-01-11 | １，４−ジヒドロピリジン誘導体 |
| JP259782 | 1982-01-11 | ||
| JP2839182 | 1982-02-24 | ||
| JP2839182A JPS58146565A (ja) | 1982-02-24 | 1982-02-24 | １，４−ジヒドロピリジン誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8204014A NL8204014A (nl) | 1983-05-16 |
| NL194203B NL194203B (nl) | 2001-05-01 |
| NL194203C true NL194203C (nl) | 2001-09-04 |
Family
ID=27275435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8204014A NL194203C (nl) | 1981-10-19 | 1982-10-18 | 1,4-dihydropyridineverbindingen en farmaceutisch preparaat dat ÚÚn of meer van deze bevat. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4446325A (de) |
| KR (1) | KR880002704B1 (de) |
| AU (1) | AU555036B2 (de) |
| CA (1) | CA1177079A (de) |
| CH (1) | CH650498A5 (de) |
| DE (1) | DE3238705A1 (de) |
| ES (2) | ES8406439A1 (de) |
| FR (1) | FR2514761B1 (de) |
| GB (1) | GB2111978B (de) |
| IT (1) | IT1189393B (de) |
| NL (1) | NL194203C (de) |
| SE (1) | SE442864B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE57810B1 (en) * | 1984-03-27 | 1993-04-21 | Delagrange Lab | 1,4-dihydropyridine derivatives,their preparation and their use |
| FR2577552B1 (fr) * | 1985-02-20 | 1987-09-04 | Sori Soc Rech Ind | Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique |
| US4833150A (en) * | 1985-03-14 | 1989-05-23 | Nelson Research & Development Co. | 1,4-dihydropyridines |
| DE3514865A1 (de) * | 1985-04-25 | 1986-11-06 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridin-derivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| US4849436A (en) * | 1986-03-11 | 1989-07-18 | Nelson Research & Development Co. | 1,4-dihydropyridines |
| EP0272336B1 (de) * | 1986-12-18 | 1991-10-23 | Kurt H. Prof. Dr. Bauer | Gegenüber Lichteinfluss stabilisiertes Nifedipin-Konzentrat und Verfahren zu seiner Herstellung |
| AU4688301A (en) * | 2000-04-11 | 2001-10-23 | Sankyo Co | Stabilized pharmaceutical compositions containing calcium channel blockers |
| AP2005003232A0 (en) | 2002-08-19 | 2005-03-31 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
| AU2005269465A1 (en) * | 2004-07-26 | 2006-02-09 | Cotherix, Inc. | Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation |
| EP2351569B1 (de) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Kombinationstherapie mit Fasudil zur Behandlung von pulmonaler Hypertonie |
| ATE551059T1 (de) * | 2005-10-26 | 2012-04-15 | Asahi Kasei Pharma Corp | Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie |
| TW200806648A (en) * | 2005-11-29 | 2008-02-01 | Sankyo Co | Acid addition salts of dihydropyridine derivatives |
| TW200736245A (en) * | 2005-11-29 | 2007-10-01 | Sankyo Co | Acid addition salts of optically active dihydropyridine derivatives |
| WO2012037665A1 (en) | 2010-09-24 | 2012-03-29 | Oral Delivery Technology Ltd. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
| CN103906508A (zh) | 2011-08-26 | 2014-07-02 | 沃克哈特有限公司 | 治疗心血管疾病的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670824C3 (de) * | 1967-03-20 | 1978-08-03 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-33-dicarbonsäurealkylester |
| DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
| DE2228363A1 (de) * | 1972-06-10 | 1974-01-03 | Bayer Ag | 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2747513A1 (de) * | 1977-10-22 | 1979-05-03 | Bayer Ag | Dihydropyridine mit schwefelhaltigen estergruppierungen |
| DE2847236A1 (de) * | 1978-10-31 | 1980-05-14 | Bayer Ag | Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2935451A1 (de) * | 1979-09-01 | 1981-03-19 | Bayer Ag, 5090 Leverkusen | Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel |
| NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
-
1982
- 1982-10-11 GB GB08229020A patent/GB2111978B/en not_active Expired
- 1982-10-13 AU AU89317/82A patent/AU555036B2/en not_active Expired
- 1982-10-18 CH CH6058/82A patent/CH650498A5/de not_active IP Right Cessation
- 1982-10-18 IT IT49295/82A patent/IT1189393B/it active
- 1982-10-18 NL NL8204014A patent/NL194203C/nl not_active IP Right Cessation
- 1982-10-18 SE SE8205905A patent/SE442864B/sv not_active IP Right Cessation
- 1982-10-19 KR KR8204705A patent/KR880002704B1/ko active
- 1982-10-19 US US06/435,183 patent/US4446325A/en not_active Expired - Lifetime
- 1982-10-19 DE DE19823238705 patent/DE3238705A1/de active Granted
- 1982-10-19 CA CA000413717A patent/CA1177079A/en not_active Expired
- 1982-10-19 ES ES517022A patent/ES8406439A1/es not_active Expired
- 1982-10-19 FR FR8217497A patent/FR2514761B1/fr not_active Expired
-
1983
- 1983-11-30 ES ES527980A patent/ES8504127A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES527980A0 (es) | 1985-04-16 |
| FR2514761B1 (fr) | 1985-09-06 |
| ES517022A0 (es) | 1984-08-16 |
| KR880002704B1 (ko) | 1988-12-26 |
| CH650498A5 (de) | 1985-07-31 |
| SE8205905D0 (sv) | 1982-10-18 |
| FR2514761A1 (fr) | 1983-04-22 |
| AU8931782A (en) | 1983-04-28 |
| NL8204014A (nl) | 1983-05-16 |
| GB2111978B (en) | 1985-05-01 |
| IT8249295A0 (it) | 1982-10-18 |
| DE3238705A1 (de) | 1983-07-14 |
| IT1189393B (it) | 1988-02-04 |
| US4446325A (en) | 1984-05-01 |
| SE8205905L (sv) | 1983-04-20 |
| NL194203B (nl) | 2001-05-01 |
| DE3238705C2 (de) | 1989-11-09 |
| SE442864B (sv) | 1986-02-03 |
| ES8504127A1 (es) | 1985-04-16 |
| ES8406439A1 (es) | 1984-08-16 |
| AU555036B2 (en) | 1986-09-11 |
| CA1177079A (en) | 1984-10-30 |
| GB2111978A (en) | 1983-07-13 |
| KR840001954A (ko) | 1984-06-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL194203C (nl) | 1,4-dihydropyridineverbindingen en farmaceutisch preparaat dat ÚÚn of meer van deze bevat. | |
| DK170891B1 (da) | 1,4-dihydropyridin-3,5-dicarboxylsyrederivater og fremgangsmåde til fremstilling deraf samt farmaceutisk middel indeholdende dem | |
| US4772621A (en) | Antihypertensive diphenylpropyl aminopropyl ester of 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylic acid | |
| EP0094159B1 (de) | Dihydropyridinderivate, deren Herstellung und Verwendung | |
| HU184821B (en) | Process for preparing new optically active derivatives of 1,4-dihydro-pyridine | |
| CA1238048A (en) | Cardiovascular active 1,4,:3,6-dianhydrohexitol esters of 1,4-dihydropyridine-3,5-dicarboxylic acids | |
| CZ127396A3 (en) | Short time acting dihydropyridines | |
| EP0097821A2 (de) | Dihydropyridine mit Calciumantagonistischer Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen | |
| KR960009427B1 (ko) | 1,4-디히드로피리딘 유도체, 그의 약학적 조성물 및 그 제조방법 | |
| HU184434B (en) | Process for preparing 1,4-dihydro-pyridine derivatives containing different substituents in position 2. and 6. and pharmaceutical compositions containing such compounds as active substances | |
| EP0207674B1 (de) | 1,4-Dihydropyridinderivate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung | |
| US4874773A (en) | 3-Aminocarbonyl-1,4-dihydropyridine-5-carboxylic acid compounds, and pharmaceutical composition containing the same | |
| US4806544A (en) | Asymmetrical ester derivatives of 1,4-dihydrophyridine-3,5-dicarboxylic acid | |
| KR900004923B1 (ko) | 1,4-디히드로피리딘 유도체의 제조방법 | |
| KR100532028B1 (ko) | 1,4-디하이드로피리딘-5-카르복실산 에스테르 유도체와그들의 제조방법 | |
| EP0105881B1 (de) | Cyanguanidine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
| JPS6352031B2 (de) | ||
| CA1257600A (en) | Isopropyl 2-(3-trifluoromethylphenoxy)-ethyl 1,4- dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5- dicarboxylate, several processes for its preparation and its use in medicaments | |
| US4634712A (en) | Antihypertensive esters of 1,4-dihydro-2,6-dimethyl-3-(alkoxycarbonyl or alkoxyalkoxycarbonyl)-4-(substituted phenyl)-pyridine-5-carboxylic acid | |
| JPS6121627B2 (de) | ||
| NZ207716A (en) | 3-(2-furoyl)-5-alkoxy-2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine derivatives and pharmaceutical compositions | |
| JPH054396B2 (de) | ||
| KR860001948B1 (ko) | 1,4-디히드로피리딘 유도체의 제조방법 | |
| DK152359B (da) | 6-formyl-1,4-dihydropyridinderivater til anvendelse som mellemprodukter ved fremstilling af farmaceutisk aktive 6-cyano-1,4-dihydropyridinderivater |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| V4 | Discontinued because of reaching the maximum lifetime of a patent |
Free format text: 20021018 |