NL188166C - Polymeren van polyketeenacetalen en polyolen, werkwijze ter bereiding daarvan en gevormde voortbrengselen daaruit. - Google Patents

Polymeren van polyketeenacetalen en polyolen, werkwijze ter bereiding daarvan en gevormde voortbrengselen daaruit.

Info

Publication number
NL188166C
NL188166C NLAANVRAGE8120177,A NL8120177A NL188166C NL 188166 C NL188166 C NL 188166C NL 8120177 A NL8120177 A NL 8120177A NL 188166 C NL188166 C NL 188166C
Authority
NL
Netherlands
Prior art keywords
polyketene
acetals
polyols
polymers
preparing
Prior art date
Application number
NLAANVRAGE8120177,A
Other languages
English (en)
Dutch (nl)
Other versions
NL8120177A (nl
Original Assignee
Stanford Res Inst Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stanford Res Inst Int filed Critical Stanford Res Inst Int
Publication of NL8120177A publication Critical patent/NL8120177A/nl
Application granted granted Critical
Publication of NL188166C publication Critical patent/NL188166C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Polyurethanes Or Polyureas (AREA)
NLAANVRAGE8120177,A 1980-05-15 1981-05-08 Polymeren van polyketeenacetalen en polyolen, werkwijze ter bereiding daarvan en gevormde voortbrengselen daaruit. NL188166C (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15005280 1980-05-15
US06/150,052 US4304767A (en) 1980-05-15 1980-05-15 Polymers of di- (and higher functionality) ketene acetals and polyols
US8100621 1981-05-08
PCT/US1981/000621 WO1981003278A1 (en) 1980-05-15 1981-05-08 Polymers of polyketene acetals and polyols

Publications (2)

Publication Number Publication Date
NL8120177A NL8120177A (nl) 1982-04-01
NL188166C true NL188166C (nl) 1992-04-16

Family

ID=22532907

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE8120177,A NL188166C (nl) 1980-05-15 1981-05-08 Polymeren van polyketeenacetalen en polyolen, werkwijze ter bereiding daarvan en gevormde voortbrengselen daaruit.

Country Status (20)

Country Link
US (1) US4304767A (de)
EP (1) EP0051667B1 (de)
JP (5) JPH039127B2 (de)
AT (1) AT384615B (de)
AU (1) AU543991B2 (de)
BE (1) BE888829A (de)
CA (1) CA1186438A (de)
CH (1) CH657369A5 (de)
DE (1) DE3148618A1 (de)
DK (1) DK16082A (de)
ES (1) ES502255A0 (de)
GB (1) GB2086404B (de)
GR (1) GR74902B (de)
IE (1) IE51287B1 (de)
NL (1) NL188166C (de)
NZ (1) NZ197036A (de)
PT (1) PT73035B (de)
SE (1) SE455791B (de)
WO (1) WO1981003278A1 (de)
ZA (1) ZA813269B (de)

Families Citing this family (163)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4489056A (en) * 1982-06-30 1984-12-18 Merck & Co., Inc. Acid anhydrides as rate controlling agent for the erosion of polymers which latter polymers have beneficial substances dispersed throughout their matrix or where the polymer matrix surrounds the beneficial substance
US4513143A (en) * 1982-12-01 1985-04-23 Sri International Preparation of ketene acetals
US4532335A (en) * 1983-03-07 1985-07-30 Sri International Preparation of ketene acetals by rearrangement of allyl and substituted allyl acetals
US4639366A (en) * 1984-06-06 1987-01-27 Merck & Co., Inc. Polymers containing pendant acid functionalities and labile backbone bonds
US4549010A (en) * 1984-06-27 1985-10-22 Merck & Co., Inc. Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal
US4754745A (en) * 1984-11-21 1988-07-05 Horowitz Bruce S Conformable sheet material for use in brachytherapy
US4697575A (en) * 1984-11-21 1987-10-06 Henry Ford Hospital Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member
US4780319A (en) * 1985-07-08 1988-10-25 Merck & Co., Inc. Organic acids as catalysts for the erosion of polymers
US4764364A (en) * 1986-02-25 1988-08-16 S R I International Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product
US4855132A (en) * 1986-02-25 1989-08-08 S R I International Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product
US4763642A (en) * 1986-04-07 1988-08-16 Horowitz Bruce S Intracavitational brachytherapy
ATE97929T1 (de) * 1986-05-15 1993-12-15 Hoechst Ag Biologisch abbaubare polymere fuer depotzubereitungen mit kontrollierter wirkstoffabgabe.
US4713441A (en) * 1986-08-01 1987-12-15 Sandoz Pharmaceuticals Corp. Polyacetal hydrogels formed from divinyl ethers and polyols
US4842868A (en) * 1986-09-26 1989-06-27 Helwing Robert F Covalently bonded active agents with carbonium ion base groups
DE3700128A1 (de) * 1987-01-03 1988-07-14 Hoechst Ag Biologisch abbaubare poly- (hydroxyalkyl)- aminodicarbonsaeure-derivate, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
US4913903A (en) * 1987-02-04 1990-04-03 Alza Corporation Post-surgical applications for bioerodible polymers
US4957986A (en) * 1988-08-02 1990-09-18 E. I. Du Pont De Nemours And Company Partially fluorinated polyesters from ketene acetals and fluorine monomers
US4906714A (en) * 1988-08-02 1990-03-06 E. I. Du Pont De Nemours And Company Partially fluorinated polyesters from ketene acetals and fluorinated vinyl monomers
US4957998A (en) * 1988-08-22 1990-09-18 Pharmaceutical Delivery Systems, Inc. Polymers containing acetal, carboxy-acetal, ortho ester and carboxyortho ester linkages
US5108755A (en) * 1989-04-27 1992-04-28 Sri International Biodegradable composites for internal medical use
US4946931A (en) * 1989-06-14 1990-08-07 Pharmaceutical Delivery Systems, Inc. Polymers containing carboxy-ortho ester and ortho ester linkages
US5013821A (en) * 1989-06-15 1991-05-07 Pharmaceutical Delivery Systems, Inc. Ortho and thio-ortho ester polymer
US5030457A (en) * 1989-08-28 1991-07-09 Pharmaceutical Delivery Systems, Inc. Bioerodible polymers useful for the controlled release of therapeutic agents
KR920702383A (ko) * 1989-08-28 1992-09-03 원본미기재 치료제의 방출을 조절하는데 유용한 생부식성 중합체
US5047464A (en) * 1989-09-20 1991-09-10 Merck & Co., Inc. Bioerodible thermoset elastomers
US5217712A (en) * 1989-09-20 1993-06-08 Merck & Co., Inc. Bioerodible thermoset elastomers
DE4002736A1 (de) * 1990-01-31 1991-08-01 Hoechst Ag Biologisch abbaubare polymere, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
NZ239370A (en) * 1990-08-22 1994-04-27 Merck & Co Inc Bioerodible implantable controlled release dosage form comprising a poly(ortho ester) or a polyacetal with an active agent incorporated into the chain backbone
JPH04120376U (ja) * 1991-04-16 1992-10-28 横河電機株式会社 リレ−検査回路
US5211951A (en) * 1991-07-24 1993-05-18 Merck & Co., Inc. Process for the manufacture of bioerodible poly (orthoester)s and polyacetals
US5254345A (en) * 1991-10-11 1993-10-19 Merck & Co., Inc. Poly(orthocarbonate acetal) bioerodible polymers
US5461140A (en) * 1992-04-30 1995-10-24 Pharmaceutical Delivery Systems Bioerodible polymers for solid controlled release pharmaceutical compositions
KR950702217A (ko) * 1993-05-03 1995-06-19 에드워드 케이. 웰치 2세 전자부화 알켄-티올 폴리머내의 폴리머 분산액정(polymer dispersed liquid crystals in electron-rich alkene-thiol polymers)
US5401885A (en) * 1993-06-01 1995-03-28 Huls America, Inc. Method of preparing ortho esters and 1.1-dialkoxycycloalkanes
US5442033A (en) * 1993-07-20 1995-08-15 Ethicon, Inc. Liquid copolymers of epsilon-caprolactone and lactide
ES2109136B1 (es) * 1994-04-22 1998-07-01 Vita Invest Sa Polimeros biodegradables de esqueleto carbonado de acetales de centeno y alcoholes, procedimiento para su obtencion y composicion y utilizacion correspondientes.
US5811510A (en) * 1995-04-14 1998-09-22 General Hospital Corporation Biodegradable polyacetal polymers and methods for their formation and use
FI98136C (fi) 1995-09-27 1997-04-25 Biocon Oy Kudosolosuhteissa hajoava materiaali ja menetelmä sen valmistamiseksi
US5968543A (en) * 1996-01-05 1999-10-19 Advanced Polymer Systems, Inc. Polymers with controlled physical state and bioerodibility
US5939453A (en) * 1998-06-04 1999-08-17 Advanced Polymer Systems, Inc. PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
WO2000002564A1 (en) * 1998-07-10 2000-01-20 The University Of Sydney Prophylactic treatments of neovascularisation in macular degeneration
AUPQ496500A0 (en) * 2000-01-06 2000-02-03 University Of Sydney, The Kit
US6613355B2 (en) * 2000-05-11 2003-09-02 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
US20050042194A1 (en) 2000-05-11 2005-02-24 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
WO2002020663A2 (en) 2000-09-06 2002-03-14 Ap Pharma, Inc. Degradable polyacetal polymers
US6590059B2 (en) * 2001-05-11 2003-07-08 Ap Pharma, Inc. Bioerodible polyorthoesters from dioxolane-based diketene acetals
EP1395626A1 (de) * 2001-05-11 2004-03-10 AP Pharma, Inc. Peg-poe, peg-poe-peg, und oe-peg-poe- blockcopolymere
US6524606B1 (en) 2001-11-16 2003-02-25 Ap Pharma, Inc. Bioerodible polyorthoesters containing amine groups
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
US20040062778A1 (en) * 2002-09-26 2004-04-01 Adi Shefer Surface dissolution and/or bulk erosion controlled release compositions and devices
US7354574B2 (en) * 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
US7045589B2 (en) * 2002-11-15 2006-05-16 A.P. Pharma, Inc. Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
US6863782B2 (en) * 2002-11-15 2005-03-08 A.P. Pharma, Inc. Method of preparing di(ketene acetals)
JP2006522133A (ja) * 2003-03-31 2006-09-28 アルザ・コーポレーション 非水性単一相の媒体、及び、そのような媒体を利用するフォーミュレーション
US7056591B1 (en) 2003-07-30 2006-06-06 Advanced Cardiovascular Systems, Inc. Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same
US7083802B2 (en) * 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
US20050181018A1 (en) * 2003-09-19 2005-08-18 Peyman Gholam A. Ocular drug delivery
US7083803B2 (en) * 2003-09-19 2006-08-01 Advanced Ocular Systems Limited Ocular solutions
US7087237B2 (en) * 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions
US7329413B1 (en) * 2003-11-06 2008-02-12 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
US7220816B2 (en) 2003-12-16 2007-05-22 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same
US7435788B2 (en) 2003-12-19 2008-10-14 Advanced Cardiovascular Systems, Inc. Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
EP1711186A4 (de) * 2004-02-04 2009-03-18 Retmed Pty Ltd Langsam freigesetzte steroidzusammensetzung
EP1718314A1 (de) * 2004-02-26 2006-11-08 Advanced Ocular Systems Limited Heparin zur behandlung von augenerkrankungen
US20050192257A1 (en) * 2004-02-26 2005-09-01 Peyman Gholam A. Predictors for patients at risk for glaucoma from steroid therapy
US8685431B2 (en) 2004-03-16 2014-04-01 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on copolymers having ester bonds and methods for fabricating the same
US8778014B1 (en) 2004-03-31 2014-07-15 Advanced Cardiovascular Systems, Inc. Coatings for preventing balloon damage to polymer coated stents
SI1755616T1 (sl) 2004-04-08 2014-04-30 Eye Co Pty Ltd. Zdravljenje eksudativne retinopatije z mineralkortikoidi
EP1740168A2 (de) * 2004-04-21 2007-01-10 Advanced Ocular Systems Limited Antiprostaglandine zur behandlung von augenpathologien
US20050288481A1 (en) * 2004-04-30 2005-12-29 Desnoyer Jessica R Design of poly(ester amides) for the control of agent-release from polymeric compositions
US7820732B2 (en) 2004-04-30 2010-10-26 Advanced Cardiovascular Systems, Inc. Methods for modulating thermal and mechanical properties of coatings on implantable devices
US20050271700A1 (en) * 2004-06-03 2005-12-08 Desnoyer Jessica R Poly(ester amide) coating composition for implantable devices
US20050287184A1 (en) 2004-06-29 2005-12-29 Hossainy Syed F A Drug-delivery stent formulations for restenosis and vulnerable plaque
US7350479B2 (en) * 2004-09-10 2008-04-01 United States Of America As Represented By The Secretary Of The Army System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp
US7166680B2 (en) 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
US7390497B2 (en) 2004-10-29 2008-06-24 Advanced Cardiovascular Systems, Inc. Poly(ester amide) filler blends for modulation of coating properties
US8609123B2 (en) 2004-11-29 2013-12-17 Advanced Cardiovascular Systems, Inc. Derivatized poly(ester amide) as a biobeneficial coating
US20060122152A1 (en) * 2004-12-03 2006-06-08 Peyman Gholam A Heparin for the treatment of ocular pathologies
US7419504B2 (en) 2004-12-27 2008-09-02 Advanced Cardiovascular Systems, Inc. Poly(ester amide) block copolymers
US8007775B2 (en) 2004-12-30 2011-08-30 Advanced Cardiovascular Systems, Inc. Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
US7202325B2 (en) 2005-01-14 2007-04-10 Advanced Cardiovascular Systems, Inc. Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles
CA2601547A1 (en) * 2005-03-31 2006-10-05 Ap Pharma, Inc. Peg-poly(ortho ester) graft copolymers and pharmaceutical compositions
CA2601546A1 (en) * 2005-03-31 2006-10-05 Ap Pharma, Inc. Peg-polyacetal diblock and triblock copolymers and pharmaceutical compositions
CA2615990A1 (en) 2005-07-18 2007-01-25 Minu, L.L.C. Enhanced ocular neuroprotection/neurostimulation
US20070014760A1 (en) 2005-07-18 2007-01-18 Peyman Gholam A Enhanced recovery following ocular surgery
US20070020312A1 (en) * 2005-07-20 2007-01-25 Desnoyer Jessica R Method of fabricating a bioactive agent-releasing implantable medical device
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US8377462B2 (en) * 2005-07-29 2013-02-19 Advanced Cardiovascular Systems, Inc. PEA-TEMPO/PEA-BZ coatings for controlled delivery of drug from implantable medical devices
US20070066493A1 (en) * 2005-09-22 2007-03-22 Halliburton Energy Services, Inc. Orthoester-based surfactants and associated methods
US7713916B2 (en) 2005-09-22 2010-05-11 Halliburton Energy Services, Inc. Orthoester-based surfactants and associated methods
US7919637B2 (en) * 2005-10-11 2011-04-05 Fujifilm Corporation Fluorine-containing spiroacetal compound and method of producing the same
EP2676691B1 (de) 2005-11-17 2016-07-06 Zogenix, Inc. Abgabe von viskosen Formulierungen durch nadellose Injektion
US7910152B2 (en) 2006-02-28 2011-03-22 Advanced Cardiovascular Systems, Inc. Poly(ester amide)-based drug delivery systems with controlled release rate and morphology
EP2374472B9 (de) 2006-03-16 2019-06-12 Dyax Corp. Zusammensetzungen und Verfahren zur Behandlung von Augenerkrankungen
US20070264338A1 (en) * 2006-05-12 2007-11-15 Shah Devang T Base-stabilized polyorthoester formulations
US20070265329A1 (en) * 2006-05-12 2007-11-15 Devang Shah T Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
US20070264339A1 (en) * 2006-05-12 2007-11-15 Ap Pharma, Inc. Base-stabilized polyorthoester formulations
US20070281870A1 (en) * 2006-06-02 2007-12-06 Halliburton Energy Services, Inc. Stimuli-degradable gels
US7306040B1 (en) * 2006-06-02 2007-12-11 Halliburton Energy Services, Inc. Stimuli-degradable gels
US20090258028A1 (en) * 2006-06-05 2009-10-15 Abbott Cardiovascular Systems Inc. Methods Of Forming Coatings For Implantable Medical Devices For Controlled Release Of A Peptide And A Hydrophobic Drug
US8323676B2 (en) * 2008-06-30 2012-12-04 Abbott Cardiovascular Systems Inc. Poly(ester-amide) and poly(amide) coatings for implantable medical devices for controlled release of a protein or peptide and a hydrophobic drug
US7458953B2 (en) * 2006-06-20 2008-12-02 Gholam A. Peyman Ocular drainage device
WO2008005371A2 (en) * 2006-06-29 2008-01-10 Medtronic, Inc. Poly(orthoester) polymers, and methods of making and using same
US7771739B2 (en) * 2006-06-30 2010-08-10 Abbott Cardiovascular Systems Inc. Implantable medical devices comprising semi-crystalline poly(ester-amide)
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
CN101505794B (zh) 2006-07-10 2013-09-04 艾斯巴技术,爱尔康生物医药研究装置有限责任公司 穿过上皮和/或内皮层的scFV抗体
US7731987B2 (en) * 2006-07-13 2010-06-08 Advanced Cardiovascular Systems, Inc. Implantable medical device comprising a pro-healing poly(ester-amide)
US20090181063A1 (en) * 2006-07-13 2009-07-16 Michael Huy Ngo Implantable medical device comprising a pro-healing poly(ester-amide)
US8030436B2 (en) * 2006-07-13 2011-10-04 Advanced Cardiovascular Systems, Inc. Poly(ester-amide) elastomers and their use with implantable medical devices
US20080014245A1 (en) * 2006-07-14 2008-01-17 Stephen Pacetti Drug-eluting implantable medical device with free radical scavenger for protecting drugs during sterilization and related method
US8268347B1 (en) 2006-10-24 2012-09-18 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
KR20140032505A (ko) 2006-11-09 2014-03-14 알콘 리서치, 리미티드 약물 전달용 수불용성 폴리머 매트릭스
US20080114076A1 (en) * 2006-11-09 2008-05-15 Alcon Manufacturing Ltd. Punctal plug comprising a water-insoluble polymeric matrix
US20080175882A1 (en) * 2007-01-23 2008-07-24 Trollsas Mikael O Polymers of aliphatic thioester
US20080306584A1 (en) * 2007-06-05 2008-12-11 Pamela Kramer-Brown Implantable medical devices for local and regional treatment
US8252361B2 (en) * 2007-06-05 2012-08-28 Abbott Cardiovascular Systems Inc. Implantable medical devices for local and regional treatment
US9737638B2 (en) * 2007-06-20 2017-08-22 Abbott Cardiovascular Systems, Inc. Polyester amide copolymers having free carboxylic acid pendant groups
US7927621B2 (en) * 2007-06-25 2011-04-19 Abbott Cardiovascular Systems Inc. Thioester-ester-amide copolymers
US8956642B2 (en) 2008-04-18 2015-02-17 Medtronic, Inc. Bupivacaine formulation in a polyorthoester carrier
US8940315B2 (en) 2008-04-18 2015-01-27 Medtronic, Inc. Benzodiazepine formulation in a polyorthoester carrier
CA2722743A1 (en) 2008-04-28 2009-11-05 Zogenix, Inc. Novel formulations for treatment of migraine
US8889172B1 (en) 2008-04-30 2014-11-18 Abbott Cardiovascular Systems Inc. Amorphous or semi-crystalline poly(ester amide) polymer with a high glass transition temperature
JP2011519638A (ja) * 2008-05-07 2011-07-14 オービージェイ・リミテッド 経皮拡散促進のための方法および装置
US8765162B2 (en) * 2008-06-30 2014-07-01 Abbott Cardiovascular Systems Inc. Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same
MX2011000629A (es) 2008-07-17 2011-04-26 Merial Ltd Formulaciones analgesicas inyectables de larga duracion para animales.
US20100047319A1 (en) * 2008-08-21 2010-02-25 Michael Huy Ngo Biodegradable Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices With Enhanced Bioabsorption Times
WO2010068827A1 (en) * 2008-12-11 2010-06-17 A.P. Pharma, Inc. Methods for enhancing stability of polyorthoesters and their formulations
EP2488640B1 (de) 2009-10-14 2018-09-26 Nanyang Technological University Antiproliferationsmittel
EP2343046A1 (de) 2010-01-08 2011-07-13 Nirvana's Tree House B.V. Funktionalisierte Triblockcopolymere und Zusammensetzungen, die solche Polymere enthalten
JP5809251B2 (ja) 2010-05-25 2015-11-10 インターナショナル・サイエンティフィック・プロプライエタリー・リミテッド 口腔ケア製品の送達
WO2011156869A1 (en) 2010-06-17 2011-12-22 International Scientific Pty Ltd Delivery of skin care products
CA2827330A1 (en) 2011-02-23 2012-08-30 Ams Research Corporation Pelvic implant and therapeutic agent system and method
WO2012116209A1 (en) 2011-02-23 2012-08-30 Ams Research Corporation Drug releasing pelvic treatment system and method
DK2790681T4 (da) 2011-11-18 2023-05-01 Regeneron Pharma Fremgangsmåde til fremstilling af en farmaceutisk formulering med langvarig frigivelse omfattende polymercoatede proteinmikropartikler ved anvendelse af spraytørring
US9849180B2 (en) 2014-09-15 2017-12-26 Hui Rong Shen Long-acting semi-solid lipid formulations
US10220093B2 (en) 2013-02-28 2019-03-05 Mira Pharma Corporation Long-acting semi-solid lipid formulations
US9592227B2 (en) 2013-03-15 2017-03-14 Heron Therapeutics, Inc. Compositions of a polyorthoester and an aprotic solvent
EP3134070B1 (de) 2014-04-21 2020-09-23 Heron Therapeutics, Inc. Zusammensetzungen aus einem polyorthoester und einem organischen sauren trägerstoff
EP3509601A1 (de) 2014-04-21 2019-07-17 Heron Therapeutics, Inc. Pharmazeutische zusammensetzung mit einem abgabesystem, einem amidartigen lokalanesthetikum und meloxicam
DK3134068T3 (da) 2014-04-21 2021-10-04 Heron Therapeutics Inc Langtidsvirkende polymerafgivelsessystemer
US9801945B2 (en) 2014-04-21 2017-10-31 Heron Therapeutics, Inc. Long-acting polymeric delivery systems
WO2015188223A1 (en) 2014-06-11 2015-12-17 International Scientific Pty Ltd Device and method to treat or prevent joint degeneration
AU2016342374B2 (en) 2015-10-23 2022-08-04 Lyndra Therapeutics, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
US11992552B2 (en) 2015-12-08 2024-05-28 Lyndra Therapeutics, Inc. Geometric configurations for gastric residence systems
JP7185526B2 (ja) 2015-12-16 2022-12-07 リジェネロン・ファーマシューティカルズ・インコーポレイテッド タンパク質微粒子の組成物及び製造方法
CN110022861B (zh) 2016-09-30 2024-06-28 林德拉治疗公司 用于金刚烷类药物缓释的胃驻留系统
CN110637022B (zh) 2017-04-24 2022-09-16 共晶制药公司 可作为流感病毒复制抑制剂的吡咯并嘧啶衍生物
US12023406B2 (en) 2017-06-09 2024-07-02 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
CA3067558A1 (en) 2017-06-16 2018-12-20 Avery Therapeutics, Inc. Three dimensional tissue compositions and methods of use
CN111511338B (zh) 2017-09-20 2022-11-29 林德拉治疗公司 胃驻留系统的封装
US11426418B2 (en) 2017-12-06 2022-08-30 Mira Pharma Corporation Injectable long-acting semi-solid gel formulations
US10561606B2 (en) 2017-12-06 2020-02-18 Mira Pharma Corporation Injectable long-acting local anesthetic semi-solid gel formulations
AU2019311117A1 (en) 2018-07-27 2021-02-04 Cocrystal Pharma, Inc. Pyrrolo(2,3-b)pyridin derivatives as inhibitors of influenza virus replication
WO2020055858A1 (en) 2018-09-10 2020-03-19 Cocrystal Pharma, Inc. Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication
KR20210080413A (ko) 2018-10-17 2021-06-30 코크리스탈 파마, 아이엔씨. 인플루엔자 바이러스 복제 억제제의 조합물
WO2020112716A1 (en) 2018-11-26 2020-06-04 Cocrystal Pharma, Inc. Inhibitors of influenza virus replication
JP2023502500A (ja) 2019-11-25 2023-01-24 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 非水性エマルションを使用した持続放出製剤
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
WO2021188620A1 (en) 2020-03-17 2021-09-23 Cocrystal Pharma Inc. Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
JP2023521116A (ja) 2020-04-10 2023-05-23 コクリスタル ファーマ，インコーポレイテッド ノロウイルス及びコロナウイルス複製の阻害剤
US20220160828A1 (en) 2020-11-25 2022-05-26 Regeneron Pharmaceuticals, Inc. Sustained release formulations using non-aqueous membrane emulsification
IL310394A (en) 2021-08-03 2024-03-01 Cocrystal Pharma Inc Corona virus inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2687407A (en) * 1951-07-18 1954-08-24 Dynamit Nobel Ag Production of resins from diallylidene pentaerythritol and a polyhydroxy alcohol
US2909506A (en) * 1956-07-10 1959-10-20 Union Carbide Corp Modified acrolein-pentaerythritol resins
US3087918A (en) * 1957-08-01 1963-04-30 Union Carbide Corp Modified acrolein-pentaerythritol resins
US2957856A (en) * 1958-08-29 1960-10-25 Union Carbide Corp Phosphorus-containing spirobi(metadioxane) resins
US4069307A (en) * 1970-10-01 1978-01-17 Alza Corporation Drug-delivery device comprising certain polymeric materials for controlled release of drug
US4180646A (en) * 1975-01-28 1979-12-25 Alza Corporation Novel orthoester polymers and orthocarbonate polymers
US4093709A (en) * 1975-01-28 1978-06-06 Alza Corporation Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates)
US4066747A (en) * 1976-04-08 1978-01-03 Alza Corporation Polymeric orthoesters housing beneficial drug for controlled release therefrom

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JPH02218719A (ja) 1990-08-31
AT384615B (de) 1987-12-10
ATA904081A (de) 1987-05-15
JPS60214745A (ja) 1985-10-28
DE3148618C2 (de) 1990-10-18
AU543991B2 (en) 1985-05-09
GB2086404A (en) 1982-05-12
SE455791B (sv) 1988-08-08
EP0051667A4 (de) 1982-09-15
ES8207564A1 (es) 1982-10-01
SE8200068L (sv) 1982-01-08
AU7175381A (en) 1981-12-07
PT73035A (en) 1981-06-01
GR74902B (de) 1984-07-12
JPH0216930B2 (de) 1990-04-18
ZA813269B (en) 1982-06-30
BE888829A (fr) 1981-08-28
JPH047729B2 (de) 1992-02-12
DK16082A (da) 1982-01-15
US4304767A (en) 1981-12-08
CH657369A5 (de) 1986-08-29
JPS60221424A (ja) 1985-11-06
GB2086404B (en) 1984-06-27
IE51287B1 (en) 1986-11-26
JPH03732A (ja) 1991-01-07
ES502255A0 (es) 1982-10-01
JPH039127B2 (de) 1991-02-07
NL8120177A (nl) 1982-04-01
EP0051667A1 (de) 1982-05-19
NZ197036A (en) 1984-02-03
CA1186438A (en) 1985-04-30
JPS57500613A (de) 1982-04-08
WO1981003278A1 (en) 1981-11-26
EP0051667B1 (de) 1986-03-05
PT73035B (en) 1984-10-22
IE811098L (en) 1981-11-15
JPH0355492B2 (de) 1991-08-23

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