NL181803C - Werkwijze voor de bereiding van een 3-methyl-pyrazolon-5-derivaat, geschikt als antitromboticum en trombolyticium; antitrombolisch en trombolytisch werkend geneesmiddel en werkwijze voor het bereiden ervan. - Google Patents

Werkwijze voor de bereiding van een 3-methyl-pyrazolon-5-derivaat, geschikt als antitromboticum en trombolyticium; antitrombolisch en trombolytisch werkend geneesmiddel en werkwijze voor het bereiden ervan.

Info

Publication number
NL181803C
NL181803C NLAANVRAGE7506765,A NL7506765A NL181803C NL 181803 C NL181803 C NL 181803C NL 7506765 A NL7506765 A NL 7506765A NL 181803 C NL181803 C NL 181803C
Authority
NL
Netherlands
Prior art keywords
derivative
thrombolyticium
thrombolic
thrombolytically
pyrazolone
Prior art date
Application number
NLAANVRAGE7506765,A
Other languages
English (en)
Dutch (nl)
Other versions
NL181803B (nl
NL7506765A (nl
Inventor
E Moller
I H F Meng
F Seuter
E Wehinger
H Horstmann
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NL7506765A publication Critical patent/NL7506765A/xx
Publication of NL181803B publication Critical patent/NL181803B/xx
Application granted granted Critical
Publication of NL181803C publication Critical patent/NL181803C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • C07D231/20One oxygen atom attached in position 3 or 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NLAANVRAGE7506765,A 1974-06-06 1975-06-06 Werkwijze voor de bereiding van een 3-methyl-pyrazolon-5-derivaat, geschikt als antitromboticum en trombolyticium; antitrombolisch en trombolytisch werkend geneesmiddel en werkwijze voor het bereiden ervan. NL181803C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2427272A DE2427272C3 (de) 1974-06-06 1974-06-06 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum

Publications (3)

Publication Number Publication Date
NL7506765A NL7506765A (nl) 1975-12-09
NL181803B NL181803B (nl) 1987-06-01
NL181803C true NL181803C (nl) 1987-11-02

Family

ID=5917444

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7506765,A NL181803C (nl) 1974-06-06 1975-06-06 Werkwijze voor de bereiding van een 3-methyl-pyrazolon-5-derivaat, geschikt als antitromboticum en trombolyticium; antitrombolisch en trombolytisch werkend geneesmiddel en werkwijze voor het bereiden ervan.

Country Status (32)

Country Link
US (1) US4053621A (de)
JP (1) JPS5840544B2 (de)
AR (3) AR207044A1 (de)
AT (1) AT342584B (de)
BE (1) BE829850A (de)
BG (3) BG24410A3 (de)
CA (1) CA1051001A (de)
CH (3) CH612673A5 (de)
CS (1) CS193513B2 (de)
DD (1) DD123886A5 (de)
DE (1) DE2427272C3 (de)
DK (1) DK134753C (de)
EG (1) EG11950A (de)
ES (2) ES454281A1 (de)
FI (1) FI57586C (de)
FR (1) FR2273535A1 (de)
GB (1) GB1454733A (de)
HK (1) HK26877A (de)
HU (1) HU169651B (de)
IE (1) IE41256B1 (de)
IL (1) IL47411A (de)
KE (1) KE2991A (de)
LU (1) LU72645A1 (de)
NL (1) NL181803C (de)
NO (1) NO141757C (de)
PH (2) PH12446A (de)
PL (3) PL96609B1 (de)
RO (3) RO73053A (de)
SE (1) SE414766B (de)
SU (3) SU544373A3 (de)
YU (3) YU141575A (de)
ZA (1) ZA753644B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8201321A (nl) * 1981-04-07 1982-11-01 Bayer Ag Werkwijze voor de behandeling van metastase en de groei van tumorcellen.
EP0064862B1 (de) * 1981-05-06 1986-08-13 Alcusal Incorporated Pty. Ltd. Heterocyclische Kupferkomplexe
US4540707A (en) * 1983-01-28 1985-09-10 Bayer Aktiengesellschaft Nafazatrom as a lipoxygenase inhibitor
DK143684A (da) * 1983-03-12 1984-09-13 Bayer Ag Anvendelse af pyrazolonderivater som lipoxygenasehaemmer ved terapi af isaer ischaemi og hjerterytmeforstyrrelser
USRE35801E (en) * 1985-05-20 1998-05-19 Mitsubishi Chemical Corporation Prophylactic and therapeutic composition for circulatory disorders and method of treatment
DK169672B1 (da) * 1985-05-20 1995-01-09 Mitsubishi Chem Ind Farmaceutiske præparater indeholdende pyrazolonderivater som aktiv bestanddel og anvendelsen af pyrazolonderivater til fremstilling af farmaceutiske præparater

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2476986A (en) * 1949-07-26 Elmobe louis martin
US2476987A (en) * 1949-07-26 S-acyloxy pyrazqles and method foe
US3147276A (en) * 1964-09-01 Pyrazolones
GB599919A (en) 1944-12-11 1948-03-24 Kodak Ltd Improvements in the manufacture of aminopyrazolones and their use as colour couplers
US2376380A (en) * 1945-05-22 Preparation of amino pyrazolones
GB636988A (en) * 1947-12-24 1950-05-10 Gevaert Photo Producten Naamlo Improvements in and relating to the production of colour photographic images
US2511231A (en) * 1949-03-26 1950-06-13 Eastman Kodak Co 1-cyanophenyl-3-acylamino-5-pyrazolone couplers for color photography
US2600788A (en) * 1949-06-07 1952-06-17 Eastman Kodak Co Halogen-substituted pyrazolone couplers for color photography
IT476454A (de) * 1949-08-22
US2672417A (en) * 1949-12-31 1954-03-16 Gevaert Photo Prod Nv Production of color photographic images
GB779703A (en) 1953-07-06 1957-07-24 Hoechst Ag Pyrazolone compounds and a process for making them
US2848446A (en) * 1954-02-23 1958-08-19 Saul & Co Azo dyestuffs
US3014916A (en) * 1959-01-22 1961-12-26 May & Baker Ltd Pyrazole derivatives
GB935538A (en) * 1959-04-06 1963-08-28 Stop Motion Devices Corp Stop-motion head for use on knitting machines
GB961037A (en) 1960-08-23 1964-06-17 Smith & Nephew Pyrazolones and processes for their preparation
NL279140A (de) * 1961-05-31
US3190888A (en) * 1963-08-22 1965-06-22 American Home Prod Aryloxyalkylpyrazole
DE1670529C3 (de) * 1966-07-13 1974-01-10 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Substituierte s-Triazine
GB1190914A (en) 1966-09-26 1970-05-06 Agfa Gevaert Nv 2-Pyrazolin-5-Ones and the use thereof as Colour Couplers
FR1558513A (de) * 1968-01-04 1969-02-28
GB1247688A (en) 1968-02-26 1971-09-29 Agfa Gevaert Monomeric and polymeric 2-pyrazoline-5-one colour couplers
JPS4818858B1 (de) * 1969-04-07 1973-06-08
FR2068413A1 (en) 1969-10-22 1971-08-27 Synthelabo 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives
US3615506A (en) * 1970-02-09 1971-10-26 Eastman Kodak Co Silver halide emulsions containing 3-cyclicamino-5-pyrazolone color couplers
US3694456A (en) * 1970-05-08 1972-09-26 Takeda Chemical Industries Ltd 1-disubstituted aminopyrazoles
FR2101060B1 (de) * 1970-08-14 1974-02-01 Roussel Uclaf
JPS548689B1 (de) * 1970-12-04 1979-04-18
JPS5417772B1 (de) * 1970-12-04 1979-07-03
AR207445A1 (es) * 1973-04-17 1976-10-08 Bayer Ag Procedimiento de preparacion de nuevos derivados de pirazolonas-(5)-1-substituidas
DE2319278C2 (de) 1973-04-17 1986-02-20 Bayer Ag, 5090 Leverkusen Pharmazeutisches Mittel
DE2319281A1 (de) * 1973-04-17 1974-11-07 Bayer Ag Diuretisches und antihypertensives mittel

Also Published As

Publication number Publication date
DE2427272C3 (de) 1981-10-01
BG23005A3 (de) 1977-05-20
YU141575A (en) 1982-02-28
PL93913B1 (de) 1977-07-30
NL181803B (nl) 1987-06-01
AT342584B (de) 1978-04-10
NL7506765A (nl) 1975-12-09
PL96608B1 (pl) 1978-01-31
AR207177A1 (es) 1976-09-15
JPS5113766A (en) 1976-02-03
RO73054A (ro) 1981-11-24
SU586839A3 (ru) 1977-12-30
SE414766B (sv) 1980-08-18
BG23899A3 (en) 1977-11-10
CH611889A5 (de) 1979-06-29
DK253475A (da) 1975-12-07
LU72645A1 (de) 1976-03-17
JPS5840544B2 (ja) 1983-09-06
AR207044A1 (es) 1976-09-09
SU544373A3 (ru) 1977-01-25
IE41256L (en) 1975-12-06
FR2273535B1 (de) 1978-12-01
CS193513B2 (en) 1979-10-31
SE7506435L (sv) 1975-12-08
FI57586C (fi) 1980-09-10
IL47411A (en) 1979-07-25
CH612673A5 (de) 1979-08-15
DE2427272B2 (de) 1980-07-24
RO79056A (ro) 1982-06-25
NO141757B (no) 1980-01-28
NO141757C (no) 1980-05-07
YU169281A (en) 1982-02-28
PH14053A (en) 1980-12-29
DK134753B (da) 1977-01-10
KE2991A (en) 1979-09-28
PL96609B1 (pl) 1978-01-31
BG24410A3 (en) 1978-02-10
ES454280A1 (es) 1977-12-01
FR2273535A1 (fr) 1976-01-02
NO751846L (de) 1975-12-09
IL47411A0 (en) 1975-08-31
EG11950A (en) 1978-12-31
AR207176A1 (es) 1976-09-15
PH12446A (en) 1979-03-08
US4053621A (en) 1977-10-11
RO73053A (ro) 1981-09-24
DE2427272A1 (de) 1976-01-08
FI57586B (fi) 1980-05-30
CA1051001A (en) 1979-03-20
HU169651B (de) 1977-02-28
HK26877A (en) 1977-06-10
DD123886A5 (de) 1977-01-19
AU8179775A (en) 1976-12-09
ZA753644B (en) 1976-04-28
CH612672A5 (de) 1979-08-15
ES454281A1 (es) 1977-11-16
YU169181A (en) 1982-02-28
GB1454733A (en) 1976-11-03
SU588917A3 (ru) 1978-01-15
BE829850A (fr) 1975-12-04
DK134753C (da) 1977-06-06
ATA424875A (de) 1977-08-15
IE41256B1 (en) 1979-11-21
FI751654A (de) 1975-12-07

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Legal Events

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BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee