KR840006766A - 항 진균제의 제조방법 - Google Patents

항 진균제의 제조방법 Download PDF

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Publication number
KR840006766A
KR840006766A KR1019830005566A KR830005566A KR840006766A KR 840006766 A KR840006766 A KR 840006766A KR 1019830005566 A KR1019830005566 A KR 1019830005566A KR 830005566 A KR830005566 A KR 830005566A KR 840006766 A KR840006766 A KR 840006766A
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KR
South Korea
Prior art keywords
gel
active compound
compound contains
mixture
forming agent
Prior art date
Application number
KR1019830005566A
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English (en)
Inventor
폰 비테라 미클로스 (외 3)
Original Assignee
하인쯔-게르트-뮐러, 귄터 페터스
바이엘 아크티엔 게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6178958&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR840006766(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 하인쯔-게르트-뮐러, 귄터 페터스, 바이엘 아크티엔 게젤샤프트 filed Critical 하인쯔-게르트-뮐러, 귄터 페터스
Publication of KR840006766A publication Critical patent/KR840006766A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

내용 없음

Description

항 진균제의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 통상적인 계형화보조제를 함유하는 탈무기질수중의 벤질 알코올의 1% 용액에 60°C에서 격렬히 교반하면서 겔-형성제로서 2.5내지 17.5%의 셀룰로오즈 에테르, 및 0.1내지 1.5%의 바이오폴리 사카라이드를 가하고, 혼합물을 30℃ 로 냉각시킨후, 0.05내지 1%, 바람직하게는 0.1내지 1%의 아졸유도체를 가하여 혼합물을 실온으로 냉각시킴을 특징으로 하여, 구강내 진균 감염증을 치료하는 겔 형태의 항 진균제를 제조하는 방법.
  2. 제1항에 있어서, 활성화합물로서 다음 구조식의 클로트리마졸을 함유함을 특징으로 하는 방법.
  3. 제1항에 있어서, 활성 화합물로서 다음 구조식의 비포나졸을 함유함을 특징으로 하는 방법.
  4. 제1항에 있어서, 활성 화합물로서 다음 구조식의 롬바졸을 함유함을 특징으로 하는 방법.
  5. 제1항에 있어서, 겔-형성제로서 하이드록시 프로필 셀룰로오즈를 함유함을 특징으로 하는 방법.
  6. 제1항에 있어서 안정화제 및 겔-형성제로서 바이오폴리사카라이드를 함유함을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830005566A 1982-11-25 1983-11-24 항 진균제의 제조방법 KR840006766A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3243546.0 1982-11-25
DE19823243546 DE3243546A1 (de) 1982-11-25 1982-11-25 Antimykotische mittel in gelform zur behandlung von pilzinfektionen der mundhoehle

Publications (1)

Publication Number Publication Date
KR840006766A true KR840006766A (ko) 1984-12-03

Family

ID=6178958

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830005566A KR840006766A (ko) 1982-11-25 1983-11-24 항 진균제의 제조방법

Country Status (12)

Country Link
EP (1) EP0112485B1 (ko)
JP (1) JPS59108712A (ko)
KR (1) KR840006766A (ko)
AT (1) ATE33759T1 (ko)
CA (1) CA1209920A (ko)
DE (2) DE3243546A1 (ko)
DK (1) DK538683A (ko)
ES (1) ES527514A0 (ko)
GR (1) GR79726B (ko)
IL (1) IL70290A (ko)
NO (1) NO834160L (ko)
ZA (1) ZA838774B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4542020A (en) * 1984-08-17 1985-09-17 E. R. Squibb & Sons, Inc. Long-lasting adhesive antifungal suppositories
JPS61151117A (ja) * 1984-12-25 1986-07-09 Bayer Yakuhin Kk 抗真菌ゲル製剤
DE3614095A1 (de) * 1986-04-25 1987-10-29 Goedecke Ag Oxyalkylcellulose enthaltende gelzubereitung
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
EP1508329A1 (en) * 2003-08-20 2005-02-23 Matsumoto Dental University Composition for an antifungal agent for suppressing fungal growth in an oral cavity
JP2005097271A (ja) * 2003-08-20 2005-04-14 Matsumoto Shika Univ 抗真菌剤用組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL31756C (ko) * 1962-04-26
US4056611A (en) * 1973-04-16 1977-11-01 Stiefel Laboratories, Inc. Therapeutic composition
US4313765A (en) * 1980-09-24 1982-02-02 Merck & Co., Inc. Synergistic blends of cellulase-free xanthan gum and cellulosics
DE3045915A1 (de) * 1980-12-05 1982-07-08 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern
JPS57120576A (en) * 1981-01-20 1982-07-27 Sumitomo Chem Co Ltd Novel imidazole ester
DE3106635A1 (de) * 1981-02-23 1982-09-09 Bayer Ag Antimykotisches mittel mit hoher wirkstoff-freisetzung in form von stiften

Also Published As

Publication number Publication date
NO834160L (no) 1984-05-28
EP0112485A3 (en) 1985-10-23
ZA838774B (en) 1984-07-25
EP0112485A2 (de) 1984-07-04
DE3376386D1 (en) 1988-06-01
GR79726B (ko) 1984-10-31
IL70290A0 (en) 1984-02-29
ES8502337A1 (es) 1985-01-01
IL70290A (en) 1988-01-31
ATE33759T1 (de) 1988-05-15
JPS59108712A (ja) 1984-06-23
DK538683A (da) 1984-05-26
ES527514A0 (es) 1985-01-01
DK538683D0 (da) 1983-11-24
CA1209920A (en) 1986-08-19
DE3243546A1 (de) 1984-05-30
EP0112485B1 (de) 1988-04-27

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E601 Decision to refuse application