ZA838774B - Antimycotic agents in gel form for the treatment of fungal infections of the oral cavity - Google Patents

Antimycotic agents in gel form for the treatment of fungal infections of the oral cavity

Info

Publication number
ZA838774B
ZA838774B ZA838774A ZA838774A ZA838774B ZA 838774 B ZA838774 B ZA 838774B ZA 838774 A ZA838774 A ZA 838774A ZA 838774 A ZA838774 A ZA 838774A ZA 838774 B ZA838774 B ZA 838774B
Authority
ZA
South Africa
Prior art keywords
treatment
oral cavity
fungal infections
gel form
antimycotic agents
Prior art date
Application number
ZA838774A
Inventor
Miklos Von Bittera
Karl Heinz Buechel
Manfred Plempel
Erik Regel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6178958&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA838774(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA838774B publication Critical patent/ZA838774B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Abstract

1. Antimycotic agents in gel form for the treatment of fungal infections of the oral cavity, containing azole derivatives and customary formulating auxiliaries, characterized in that they contain 2.5 % - 17.5 % of cellulose ethers as the gel-forming agent and 0.1 - 1.5 % of xanthan gum as the stabiliser and/or gel-forming agent.
ZA838774A 1982-11-25 1983-11-24 Antimycotic agents in gel form for the treatment of fungal infections of the oral cavity ZA838774B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823243546 DE3243546A1 (en) 1982-11-25 1982-11-25 ANTIMYCOTIC AGENTS IN GEL FOR TREATING FUNGAL INFECTIONS OF THE ORAL CAVES

Publications (1)

Publication Number Publication Date
ZA838774B true ZA838774B (en) 1984-07-25

Family

ID=6178958

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA838774A ZA838774B (en) 1982-11-25 1983-11-24 Antimycotic agents in gel form for the treatment of fungal infections of the oral cavity

Country Status (12)

Country Link
EP (1) EP0112485B1 (en)
JP (1) JPS59108712A (en)
KR (1) KR840006766A (en)
AT (1) ATE33759T1 (en)
CA (1) CA1209920A (en)
DE (2) DE3243546A1 (en)
DK (1) DK538683A (en)
ES (1) ES527514A0 (en)
GR (1) GR79726B (en)
IL (1) IL70290A (en)
NO (1) NO834160L (en)
ZA (1) ZA838774B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4542020A (en) * 1984-08-17 1985-09-17 E. R. Squibb & Sons, Inc. Long-lasting adhesive antifungal suppositories
JPS61151117A (en) * 1984-12-25 1986-07-09 Bayer Yakuhin Kk Gelatinous antimycotic preparation
DE3614095A1 (en) * 1986-04-25 1987-10-29 Goedecke Ag OXYALKYLCELLULOSE CONTAINING GEL PREPARATION
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
JP2005097271A (en) * 2003-08-20 2005-04-14 Matsumoto Shika Univ Composition for antifungal agent
EP1508329A1 (en) * 2003-08-20 2005-02-23 Matsumoto Dental University Composition for an antifungal agent for suppressing fungal growth in an oral cavity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE626627A (en) * 1962-04-26
US4056611A (en) * 1973-04-16 1977-11-01 Stiefel Laboratories, Inc. Therapeutic composition
US4313765A (en) * 1980-09-24 1982-02-02 Merck & Co., Inc. Synergistic blends of cellulase-free xanthan gum and cellulosics
DE3045915A1 (en) * 1980-12-05 1982-07-08 Bayer Ag, 5090 Leverkusen ANTIMYCOTIC AGENTS WITH HIGH ACTIVE SUBSTANCE RELEASE IN THE FORM OF ELASTIC LIQUID PLASTERS
JPS57120576A (en) * 1981-01-20 1982-07-27 Sumitomo Chem Co Ltd Novel imidazole ester
DE3106635A1 (en) * 1981-02-23 1982-09-09 Bayer Ag ANTIMYCOTIC AGENT WITH HIGH ACTIVE SUBSTANCE RELEASE IN THE FORM OF PEN

Also Published As

Publication number Publication date
JPS59108712A (en) 1984-06-23
DK538683D0 (en) 1983-11-24
CA1209920A (en) 1986-08-19
DK538683A (en) 1984-05-26
EP0112485B1 (en) 1988-04-27
ES8502337A1 (en) 1985-01-01
EP0112485A3 (en) 1985-10-23
DE3376386D1 (en) 1988-06-01
DE3243546A1 (en) 1984-05-30
ES527514A0 (en) 1985-01-01
EP0112485A2 (en) 1984-07-04
GR79726B (en) 1984-10-31
IL70290A (en) 1988-01-31
KR840006766A (en) 1984-12-03
IL70290A0 (en) 1984-02-29
ATE33759T1 (en) 1988-05-15
NO834160L (en) 1984-05-28

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