JPS57120576A - Novel imidazole ester - Google Patents
Novel imidazole esterInfo
- Publication number
- JPS57120576A JPS57120576A JP56007581A JP758181A JPS57120576A JP S57120576 A JPS57120576 A JP S57120576A JP 56007581 A JP56007581 A JP 56007581A JP 758181 A JP758181 A JP 758181A JP S57120576 A JPS57120576 A JP S57120576A
- Authority
- JP
- Japan
- Prior art keywords
- formulai
- carbamoyl
- alkoxycarbonyl
- reactive derivative
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- -1 imidazole ester Chemical class 0.000 title abstract 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005098 aryl alkoxy carbonyl group Chemical group 0.000 abstract 1
- 230000003327 cancerostatic effect Effects 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229940049964 oleate Drugs 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An imidazole derivative of formulaI(R1WR3 are H, halogen, alkyl, alkenyl, cyano, formyl, halogenoalkyl, alkoxycarbonyl, aralkyloxycarbonyl, acetamide, substituted alkyl, alkoxycarbonyl-substituted alkenyl, alkoxy, heterocyclic ring) and its acid adduct.
EXAMPLE: 5-Carbamoyl-1H-imidazol-4-yl acrylate.
USE: Carcinostatic agent: it has effects to inhibit the propagation of tumor cells and prolong lives.
PREPARATION: The reaction between 4-carbamoyl-imidazolium-5-oleate or its reactive derivative and a carboxylic acid of formula II or its reactive derivative gives the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56007581A JPS57120576A (en) | 1981-01-20 | 1981-01-20 | Novel imidazole ester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56007581A JPS57120576A (en) | 1981-01-20 | 1981-01-20 | Novel imidazole ester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS57120576A true JPS57120576A (en) | 1982-07-27 |
Family
ID=11669772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56007581A Pending JPS57120576A (en) | 1981-01-20 | 1981-01-20 | Novel imidazole ester |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57120576A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59108712A (en) * | 1982-11-25 | 1984-06-23 | バイエル・アクチエンゲゼルシヤフト | Antifungal |
| US4898549A (en) * | 1986-01-28 | 1990-02-06 | Omron Tateisi Electronics Co. | Connector built from one or more single rowed housings, with long lasting locking mechanism |
-
1981
- 1981-01-20 JP JP56007581A patent/JPS57120576A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59108712A (en) * | 1982-11-25 | 1984-06-23 | バイエル・アクチエンゲゼルシヤフト | Antifungal |
| US4898549A (en) * | 1986-01-28 | 1990-02-06 | Omron Tateisi Electronics Co. | Connector built from one or more single rowed housings, with long lasting locking mechanism |
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