NI201000226A - Forma cristalina de (2s) - (-) - n - ( 6 - cloro - 2, 3 - dihidro - benzo - [ 1, 4 ] dioxin - 2 - ilmetil ) - sulfamida. - Google Patents
Forma cristalina de (2s) - (-) - n - ( 6 - cloro - 2, 3 - dihidro - benzo - [ 1, 4 ] dioxin - 2 - ilmetil ) - sulfamida.Info
- Publication number
- NI201000226A NI201000226A NI201000226A NI201000226A NI201000226A NI 201000226 A NI201000226 A NI 201000226A NI 201000226 A NI201000226 A NI 201000226A NI 201000226 A NI201000226 A NI 201000226A NI 201000226 A NI201000226 A NI 201000226A
- Authority
- NI
- Nicaragua
- Prior art keywords
- crystalline form
- sulfamide
- dioxin
- benzo
- dihydro
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
La presente invención se refiere a una nueva forma cristalina de (2S) - (-) - N - ( 6 - cloro - 2, 3 - dihidro - benzo [ 1, 4] dioxin - 2 - ilmetil) - sulfamida, composiciones farmacéuticas que contienen dicha forma cristalina y el uso de la forma cristalina en el tratamiento de la ansiedad y trastornos relacionados; depresión bipolar y manía; depresión; epilepsia y trastornos relacionados; epileptogénesis; trastornos relacionados con la glucosa; trastornos relacionados con los lípidos; migraña; obesidad; dolor; abuso de sustancias; o para la neuroprotección. La presente invención se refiere, además, a un proceso para la preparación de la nueva forma cristalina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7478308P | 2008-06-23 | 2008-06-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
NI201000226A true NI201000226A (es) | 2011-08-01 |
Family
ID=41431873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NI201000226A NI201000226A (es) | 2008-06-23 | 2010-12-22 | Forma cristalina de (2s) - (-) - n - ( 6 - cloro - 2, 3 - dihidro - benzo - [ 1, 4 ] dioxin - 2 - ilmetil ) - sulfamida. |
Country Status (22)
Country | Link |
---|---|
US (1) | US8809385B2 (es) |
EP (1) | EP2340246A2 (es) |
JP (1) | JP2012530682A (es) |
AR (1) | AR072961A1 (es) |
AU (1) | AU2009271362B2 (es) |
BR (1) | BRPI0915890A2 (es) |
CA (1) | CA2729056A1 (es) |
CL (1) | CL2010001540A1 (es) |
CO (1) | CO6341554A2 (es) |
CR (1) | CR20110042A (es) |
EA (1) | EA018567B1 (es) |
EC (1) | ECSP10010707A (es) |
HN (1) | HN2010002735A (es) |
IL (1) | IL210138A0 (es) |
MX (1) | MX2011000090A (es) |
NI (1) | NI201000226A (es) |
NZ (1) | NZ590682A (es) |
PE (1) | PE20110060A1 (es) |
TW (1) | TW201012807A (es) |
UY (1) | UY31934A (es) |
WO (1) | WO2010008776A2 (es) |
ZA (1) | ZA201100570B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
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TW200612905A (en) * | 2004-06-16 | 2006-05-01 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
MY142329A (en) * | 2004-08-24 | 2010-11-15 | Janssen Pharmaceutica Nv | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents. |
KR20080012360A (ko) * | 2005-05-20 | 2008-02-11 | 얀센 파마슈티카 엔.브이. | 설파미드 유도체의 제조 방법 |
US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
US8716231B2 (en) * | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
US8492431B2 (en) * | 2005-12-19 | 2013-07-23 | Janssen Pharmaceutica, N.V. | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
US8937096B2 (en) * | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
US8497298B2 (en) * | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
US20070191474A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
TW200812573A (en) * | 2006-05-19 | 2008-03-16 | Janssen Pharmaceutica Nv | Co-therapy for the treatment of epilepsy and related disorders |
US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
US8809385B2 (en) | 2008-06-23 | 2014-08-19 | Janssen Pharmaceutica Nv | Crystalline form of (2S)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide |
US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
EP2760851A1 (en) | 2011-09-29 | 2014-08-06 | Janssen Pharmaceutica, N.V. | Process for the preparation of sulfamide derivatives |
JP2014528399A (ja) * | 2011-09-29 | 2014-10-27 | ヤンセン ファーマシューティカ エヌ.ベー. | スルファミド誘導体の改善された調製プロセス |
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-
2009
- 2009-06-19 US US12/488,079 patent/US8809385B2/en not_active Expired - Fee Related
- 2009-06-19 MX MX2011000090A patent/MX2011000090A/es active IP Right Grant
- 2009-06-19 EP EP09798447A patent/EP2340246A2/en not_active Withdrawn
- 2009-06-19 WO PCT/US2009/048026 patent/WO2010008776A2/en active Application Filing
- 2009-06-19 EA EA201170079A patent/EA018567B1/ru not_active IP Right Cessation
- 2009-06-19 PE PE2010001185A patent/PE20110060A1/es not_active Application Discontinuation
- 2009-06-19 CA CA2729056A patent/CA2729056A1/en not_active Abandoned
- 2009-06-19 NZ NZ590682A patent/NZ590682A/xx not_active IP Right Cessation
- 2009-06-19 BR BRPI0915890A patent/BRPI0915890A2/pt not_active IP Right Cessation
- 2009-06-19 AU AU2009271362A patent/AU2009271362B2/en not_active Ceased
- 2009-06-22 TW TW098120874A patent/TW201012807A/zh unknown
- 2009-06-23 AR ARP090102301A patent/AR072961A1/es not_active Application Discontinuation
- 2009-06-23 UY UY0001031934A patent/UY31934A/es unknown
-
2010
- 2010-08-12 JP JP2011516478A patent/JP2012530682A/ja active Pending
- 2010-12-21 IL IL210138A patent/IL210138A0/en unknown
- 2010-12-22 NI NI201000226A patent/NI201000226A/es unknown
- 2010-12-22 EC EC2010010707A patent/ECSP10010707A/es unknown
- 2010-12-22 HN HN2010002735A patent/HN2010002735A/es unknown
- 2010-12-23 CL CL2010001540A patent/CL2010001540A1/es unknown
- 2010-12-28 CO CO10163416A patent/CO6341554A2/es not_active Application Discontinuation
-
2011
- 2011-01-21 ZA ZA2011/00570A patent/ZA201100570B/en unknown
- 2011-01-24 CR CR20110042A patent/CR20110042A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
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CA2729056A1 (en) | 2010-01-21 |
AU2009271362A1 (en) | 2010-01-21 |
CO6341554A2 (es) | 2011-11-21 |
NZ590682A (en) | 2012-09-28 |
CR20110042A (es) | 2011-07-06 |
ECSP10010707A (es) | 2011-01-31 |
ZA201100570B (en) | 2012-06-27 |
JP2012530682A (ja) | 2012-12-06 |
AU2009271362B2 (en) | 2014-03-13 |
BRPI0915890A2 (pt) | 2015-11-03 |
MX2011000090A (es) | 2011-03-02 |
TW201012807A (en) | 2010-04-01 |
IL210138A0 (en) | 2011-03-31 |
US20090318544A1 (en) | 2009-12-24 |
EP2340246A2 (en) | 2011-07-06 |
US8809385B2 (en) | 2014-08-19 |
UY31934A (es) | 2010-01-05 |
WO2010008776A2 (en) | 2010-01-21 |
CL2010001540A1 (es) | 2011-09-23 |
WO2010008776A3 (en) | 2011-04-07 |
AU2009271362A2 (en) | 2011-05-19 |
PE20110060A1 (es) | 2011-01-31 |
WO2010008776A9 (en) | 2011-02-10 |
HN2010002735A (es) | 2014-07-31 |
EA201170079A1 (ru) | 2011-06-30 |
EA018567B1 (ru) | 2013-08-30 |
AR072961A1 (es) | 2010-10-06 |
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