MY8600452A - Process for the resolution of d, 12-(6-methoxy-2-napathyl) propionic acid. a mixture of the salts of these d and i acids;a pharmaceutical composition containing a salt of the d acid; a salt of the d acid - Google Patents

Process for the resolution of d, 12-(6-methoxy-2-napathyl) propionic acid. a mixture of the salts of these d and i acids;a pharmaceutical composition containing a salt of the d acid; a salt of the d acid

Info

Publication number
MY8600452A
MY8600452A MY452/86A MY8600452A MY8600452A MY 8600452 A MY8600452 A MY 8600452A MY 452/86 A MY452/86 A MY 452/86A MY 8600452 A MY8600452 A MY 8600452A MY 8600452 A MY8600452 A MY 8600452A
Authority
MY
Malaysia
Prior art keywords
acid
salt
napathyl
methoxy
resolution
Prior art date
Application number
MY452/86A
Other languages
English (en)
Inventor
Holton Percy George
Original Assignee
Syntex Pharmacueticals Interna
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26734026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY8600452(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/097,118 external-priority patent/US4246193A/en
Application filed by Syntex Pharmacueticals Interna filed Critical Syntex Pharmacueticals Interna
Publication of MY8600452A publication Critical patent/MY8600452A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/50—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MY452/86A 1979-07-06 1986-12-30 Process for the resolution of d, 12-(6-methoxy-2-napathyl) propionic acid. a mixture of the salts of these d and i acids;a pharmaceutical composition containing a salt of the d acid; a salt of the d acid MY8600452A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5525879A 1979-07-06 1979-07-06
US06/097,118 US4246193A (en) 1979-11-26 1979-11-26 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Publications (1)

Publication Number Publication Date
MY8600452A true MY8600452A (en) 1986-12-31

Family

ID=26734026

Family Applications (1)

Application Number Title Priority Date Filing Date
MY452/86A MY8600452A (en) 1979-07-06 1986-12-30 Process for the resolution of d, 12-(6-methoxy-2-napathyl) propionic acid. a mixture of the salts of these d and i acids;a pharmaceutical composition containing a salt of the d acid; a salt of the d acid

Country Status (27)

Country Link
EP (1) EP0022529B1 (cs)
JP (2) JPS63313749A (cs)
KR (1) KR830000769B1 (cs)
AR (1) AR225927A1 (cs)
AU (1) AU544963B2 (cs)
CA (1) CA1135717A (cs)
CZ (1) CZ277725B6 (cs)
DD (1) DD153367A5 (cs)
DE (3) DE3063969D1 (cs)
DK (2) DK156051C (cs)
ES (1) ES8105691A1 (cs)
FR (2) FR2472557A1 (cs)
GB (1) GB2054579B (cs)
GR (1) GR68796B (cs)
HK (1) HK886A (cs)
IE (1) IE50000B1 (cs)
IL (1) IL60498A (cs)
IN (1) IN152737B (cs)
IT (1) IT1130490B (cs)
MY (1) MY8600452A (cs)
NZ (1) NZ194237A (cs)
PH (4) PH15674A (cs)
PL (1) PL133439B1 (cs)
PT (1) PT71486A (cs)
RO (1) RO80655B (cs)
SK (1) SK278340B6 (cs)
YU (1) YU42673B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
ZA828453B (en) * 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
IT1196197B (it) * 1984-07-23 1988-11-10 Ravizza Spa Procedimento per la risoluzione dell'acido (+)(-) 2-(2'-(p-fluorofenil)--5'-benzossazolil)-propionico
GB9121279D0 (en) * 1991-10-08 1991-11-20 Cerestar Holding Bv Process for the production of aminopolyols
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
KR100678287B1 (ko) * 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
KR101170537B1 (ko) * 2010-01-11 2012-08-01 김창운 해수의 자연순환이 가능한 내륙 내 바다양식 수조

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1668654B2 (de) * 1967-01-13 1976-11-04 Syntex Corp., Panama 2-(6'-substituierte-2'-naphthyl)- propionsaeuren und -derivate, ihre herstellung und sie enthaltende arzneimittel
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
ZA70809B (en) * 1969-03-24 1971-09-29 Syntex Corp Amine salts of 2-(6'-methoxy-2'-naphthyl)propionic acids and processes for the preparation thereof
US3904683A (en) * 1972-08-10 1975-09-09 Syntex Corp Process for the resolution of d- and 1-2-(6-methoxy-2-naphthyl) propionic acid
CS222255B2 (en) * 1977-03-08 1983-06-24 Boots Co Ltd Method of increasing the portion of the deisred anantiometer in the acid component of the 2-arylpropion acid
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.

Also Published As

Publication number Publication date
DE3025448A1 (de) 1981-01-15
PT71486A (en) 1980-08-01
ES493126A0 (es) 1981-06-16
JPH0454B2 (cs) 1992-01-06
DE3063969D1 (en) 1983-08-04
PH15674A (en) 1983-03-11
DK156051C (da) 1989-11-06
GB2054579B (en) 1983-06-22
AU6012180A (en) 1981-01-15
FR2470108B1 (cs) 1984-04-20
RO80655B (ro) 1983-04-30
JPS63313749A (ja) 1988-12-21
GB2054579A (en) 1981-02-18
CZ277725B6 (en) 1993-04-14
IL60498A (en) 1984-06-29
DD153367A5 (de) 1982-01-06
ES8105691A1 (es) 1981-06-16
EP0022529B1 (en) 1983-06-29
RO80655A (ro) 1983-04-29
CA1135717A (en) 1982-11-16
DE3051036C2 (cs) 1988-03-31
FR2470108A1 (fr) 1981-05-29
EP0022529A1 (en) 1981-01-21
DK289080A (da) 1981-01-07
IL60498A0 (en) 1980-09-16
KR830000769B1 (ko) 1983-04-11
PH16432A (en) 1983-10-03
PH16328A (en) 1983-09-05
PL225474A1 (cs) 1981-03-27
YU42673B (en) 1988-10-31
CS477480A3 (en) 1992-11-18
IE50000B1 (en) 1986-01-22
IT8068053A0 (it) 1980-07-03
AU544963B2 (en) 1985-06-27
PL133439B1 (en) 1985-06-29
NZ194237A (en) 1984-05-31
HK886A (en) 1986-01-10
IT1130490B (it) 1986-06-11
GR68796B (cs) 1982-02-18
DE3025448C2 (cs) 1987-05-21
SK278340B6 (en) 1996-12-04
DK156051B (da) 1989-06-19
PH16431A (en) 1983-10-03
DK239988A (da) 1988-05-03
AR225927A1 (es) 1982-05-14
JPH0321535B2 (cs) 1991-03-22
DK239988D0 (da) 1988-05-03
FR2472557A1 (fr) 1981-07-03
IN152737B (cs) 1984-03-24
YU174380A (en) 1984-04-30
FR2472557B1 (cs) 1984-04-20
JPH0249749A (ja) 1990-02-20
IE801396L (en) 1981-01-06

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