MY8100371A - 5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof - Google Patents

5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof

Info

Publication number
MY8100371A
MY8100371A MY371/81A MY8100371A MY8100371A MY 8100371 A MY8100371 A MY 8100371A MY 371/81 A MY371/81 A MY 371/81A MY 8100371 A MY8100371 A MY 8100371A MY 8100371 A MY8100371 A MY 8100371A
Authority
MY
Malaysia
Prior art keywords
thenoyl
foroyl
furoyl
pyrrolo
pyrrole
Prior art date
Application number
MY371/81A
Other languages
English (en)
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/771,283 external-priority patent/US4087539A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of MY8100371A publication Critical patent/MY8100371A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
MY371/81A 1976-07-14 1981-12-30 5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof MY8100371A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70485776A 1976-07-14 1976-07-14
US05/771,283 US4087539A (en) 1976-07-14 1977-02-23 5-(2-Furoyl)-, 5-(2-thenoyl)-, 5-(3-furoyl)- and 5-(3-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof

Publications (1)

Publication Number Publication Date
MY8100371A true MY8100371A (en) 1981-12-31

Family

ID=27107392

Family Applications (1)

Application Number Title Priority Date Filing Date
MY371/81A MY8100371A (en) 1976-07-14 1981-12-30 5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof

Country Status (26)

Country Link
JP (1) JPS539789A (xx)
AR (1) AR218631A1 (xx)
AU (1) AU513385B2 (xx)
CA (1) CA1100140A (xx)
CH (2) CH644861A5 (xx)
CS (1) CS208724B2 (xx)
DE (1) DE2731662A1 (xx)
DK (1) DK152652C (xx)
ES (2) ES460705A1 (xx)
FI (1) FI63407C (xx)
FR (1) FR2361396A1 (xx)
GB (1) GB1554076A (xx)
GR (1) GR61607B (xx)
HK (1) HK17581A (xx)
IE (1) IE45302B1 (xx)
IL (1) IL52492A (xx)
IT (1) IT1117314B (xx)
MY (1) MY8100371A (xx)
NL (1) NL7707652A (xx)
NO (1) NO147563C (xx)
NZ (1) NZ184611A (xx)
PL (1) PL111408B1 (xx)
PT (1) PT66779B (xx)
SE (1) SE434644B (xx)
SU (2) SU664566A3 (xx)
YU (2) YU43157B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097579A (en) * 1977-03-31 1978-06-27 Syntex (U.S.A.) Inc. 5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4140698A (en) * 1977-07-25 1979-02-20 Syntex (Usa) Inc. 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
US4511724A (en) * 1982-06-10 1985-04-16 Merck & Co., Inc. 5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
JPS5910589A (ja) * 1982-06-10 1984-01-20 メルク　エンド　カムパニー　インコーポレーテツド 抗炎症剤および鎮痛剤として新規な５−（ピロ−ル−２−オイル）−１，２−ジヒドロ−３Ｈ−ピロロ〔１，２−ａ〕ピロ−ル誘導体
HU198927B (en) * 1987-01-14 1989-12-28 Richter Gedeon Vegyeszet Process for producing 1-/substituted aminomethyl/-octa-hydroindolo-(2,3-a)quinolizine derivatives, pharmaceutically applicable acid addition salts thereof, as well as pharmaceutical compositions comprising same
US4874871A (en) * 1987-03-25 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds

Also Published As

Publication number Publication date
FR2361396A1 (fr) 1978-03-10
FI63407C (fi) 1983-06-10
YU47583A (en) 1984-06-30
SU793400A3 (ru) 1980-12-30
ES470213A1 (es) 1979-09-16
JPS6254110B2 (xx) 1987-11-13
GB1554076A (en) 1979-10-17
SE7708142L (sv) 1978-01-15
FI772154A (xx) 1978-01-15
CH644861A5 (en) 1984-08-31
CS208724B2 (en) 1981-09-15
AU2697677A (en) 1979-01-18
YU47683A (en) 1984-04-30
AU513385B2 (en) 1980-11-27
NO147563C (no) 1983-05-18
DK152652B (da) 1988-04-05
DK152652C (da) 1988-09-12
ES460705A1 (es) 1979-10-01
NL7707652A (nl) 1978-01-17
PT66779A (fr) 1977-08-01
DK307677A (da) 1978-01-15
SE434644B (sv) 1984-08-06
NZ184611A (en) 1979-03-28
SU664566A3 (ru) 1979-05-25
NO147563B (no) 1983-01-24
IE45302B1 (en) 1982-07-28
NO772493L (no) 1978-01-17
DE2731662A1 (de) 1978-01-19
PT66779B (fr) 1978-12-18
PL199602A1 (pl) 1979-01-29
GR61607B (en) 1978-12-02
DE2731662C2 (xx) 1989-11-09
IL52492A0 (en) 1977-10-31
IT1117314B (it) 1986-02-17
FR2361396B1 (xx) 1981-11-27
JPS539789A (en) 1978-01-28
IE45302L (en) 1978-01-14
YU43156B (en) 1989-04-30
PL111408B1 (en) 1980-08-30
CH651045A5 (en) 1985-08-30
FI63407B (fi) 1983-02-28
CA1100140A (en) 1981-04-28
YU43157B (en) 1989-04-30
AR218631A1 (es) 1980-06-30
IL52492A (en) 1981-06-29
HK17581A (en) 1981-05-08

Similar Documents

Publication Publication Date Title
ZA774239B (en) 5-(2-furoyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
ZA774238B (en) 5-aroyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
YU42163B (en) Process for obtaining derivatives 3-(1h-tetrazole-5-yl)-4h-pyrido(1,2-a)pyrimidin-4-ones
AU518169B2 (en) 5-(2-PYRROLO-l, 2-DIHYDRO-3H-PYRROLO f 1 2-a 1 PYRROLE-1 CARBOXYLIC ACID DERIVATIVES
DE3869257D1 (de) N-aminobutyl-n-phenylarylamid-derivate, ihre herstellung und ihre verwendung in der heilkunde.
HK15981A (en) 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
DE2860560D1 (en) 5-substituted-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carbonitriles and process for their conversion to the corresponding 1-carboxylic acids
DE3377713D1 (en) New 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole derivatives as anti-inflammatory and analgesic agents
MY8100371A (en) 5-(2-foroyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo [1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
HU173438B (hu) Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom
DE3865073D1 (de) Imidazopyridinderivate, ihre herstellung und therapeutische verwendung.
NL7708543A (nl) Werkwijze voor het bereiden van 5-amino-1,2,3-thia- diazool en derivaten daarvan.
MTP811B (en) Indolo (3,2,1-de)(1.5) naphthyzidine derivatives
NO801376L (no) Fremgangsmaate ved fremstilling av 3-substituerte tetrahydro-pyrrolo(1,2-a)pyrimidinderivater
HRP940490B1 (en) 5-AROYL-1,2-DIHYDRO-3H-PYRROLO(1,2-a)PYRROLE-1-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THE PRODUCTION THEREOF
DE3580773D1 (de) Imidazo (1,5-a) pyridyl-methan- und imidazo (1,5-b) pyridazinyl-methan-derivate, ihre herstellung und sie enthaltende aufzeichnungsmaterialien.
DK479480A (da) (dl) 5-(2-furoyl)-,5-(2-thenoyl)-,5-(3-furoyl)-og 5-(3-thenoyl)-1,2-dihydro-3h-pyrrol-(1,2-a)-pyrrol-1-carboxylsyrer estere og salte
IT8021957A0 (it) Derivati dell'indolo, loro preparazione, medicamenti che licontengono.
AU513384C (en) 5-aroyl-l., 2-dihydro-3H-pyrrolo(1, 2-a) pyrrole 1-carboxylic acid derivatives
HU175301B (hu) Sposob poluchenija 5-zameshchjonnykh proizvodnykh 1,2-digidro-3h-pirrolo/1,2-a/pirrol-1-karbonovoj kisloty
AU1236176A (en) Diazolo, diazino and diazepino [1,2-a] otrudi azeoube derivatives
ATE83774T1 (de) 7-(1-azetidinyl)-1,4-dihydro-4-oxochinolin-3carbons|ure-derivate, ihre herstellung und ihre verwendung als arzneimittel.