MY191314A - High level production of long-chain dicarboxylic acids with microbes - Google Patents
High level production of long-chain dicarboxylic acids with microbesInfo
- Publication number
- MY191314A MY191314A MYPI2018700157A MYPI2018700157A MY191314A MY 191314 A MY191314 A MY 191314A MY PI2018700157 A MYPI2018700157 A MY PI2018700157A MY PI2018700157 A MYPI2018700157 A MY PI2018700157A MY 191314 A MY191314 A MY 191314A
- Authority
- MY
- Malaysia
- Prior art keywords
- long
- microbes
- high level
- dicarboxylic acids
- chain dicarboxylic
- Prior art date
Links
- 150000001991 dicarboxylic acids Chemical class 0.000 title 1
- 230000000813 microbial effect Effects 0.000 abstract 3
- 108010011449 Long-chain-fatty-acid-CoA ligase Proteins 0.000 abstract 2
- 102000005870 Coenzyme A Ligases Human genes 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
- C12Y602/01—Acid-Thiol Ligases (6.2.1)
- C12Y602/01003—Long-chain-fatty-acid-CoA ligase (6.2.1.3)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195338P | 2015-07-22 | 2015-07-22 | |
| US201562195340P | 2015-07-22 | 2015-07-22 | |
| PCT/US2016/043133 WO2017015368A1 (en) | 2015-07-22 | 2016-07-20 | High level production of long-chain dicarboxylic acids with microbes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY191314A true MY191314A (en) | 2022-06-15 |
Family
ID=57834583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2018700157A MY191314A (en) | 2015-07-22 | 2016-07-20 | High level production of long-chain dicarboxylic acids with microbes |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10626424B2 (enExample) |
| EP (1) | EP3325607A1 (enExample) |
| JP (1) | JP6898915B2 (enExample) |
| CN (1) | CN108138121B (enExample) |
| MY (1) | MY191314A (enExample) |
| WO (1) | WO2017015368A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107400675B (zh) * | 2017-08-29 | 2021-01-26 | 海南省农业科学院植物保护研究所 | 一种抗瓜类枯萎病活性产物基因的克隆与序列分析方法 |
| CN110684676B (zh) * | 2018-07-06 | 2023-08-08 | 上海凯赛生物技术股份有限公司 | 一种低含量羟基酸杂质的长链二元酸及其生产方法 |
| US11136596B2 (en) * | 2018-07-06 | 2021-10-05 | Cibt America Inc. | Long-chain dibasic acid with low content of hydroxyl acid impurity and production method thereof |
| CN111394400B (zh) * | 2019-01-03 | 2022-08-19 | 上海凯赛生物技术股份有限公司 | Sct1基因在长链二元酸生产中的应用 |
| CN111394399B (zh) * | 2019-01-03 | 2022-06-28 | 上海凯赛生物技术股份有限公司 | 一种降低长链二元酸中酰基甘油酯杂质含量的方法 |
| CN112301066B (zh) * | 2019-07-31 | 2022-08-02 | 上海凯赛生物技术股份有限公司 | 发酵生产长链二元酸的菌株及其制备方法与应用 |
| KR102212882B1 (ko) * | 2019-09-25 | 2021-02-08 | 한국원자력연구원 | 지방산 생산능이 증가된 클라미도모나스 속 미세조류 및 클라미도모나스 속 미세조류의 지방산 생산능을 증가시키는 방법 |
| KR102343479B1 (ko) * | 2020-06-23 | 2021-12-27 | 한국생명공학연구원 | 스핑고지질 및 스핑고이드 염기의 생산성이 향상된 피키아 시페라이 변이 균주 및 이의 제조방법 |
| WO2022235655A1 (en) | 2021-05-04 | 2022-11-10 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising insoluble alpha-glucan |
| CN115710584A (zh) * | 2021-08-18 | 2023-02-24 | 上海凯赛生物技术股份有限公司 | 超氧化物歧化酶在制备lcda中的应用及过表达其的基因工程菌 |
| CN113943760B (zh) * | 2021-12-02 | 2023-09-12 | 王婷 | 维斯假丝酵母发酵生产长链二元酸的方法、产品与菌种 |
| EP4463519A1 (en) | 2022-01-12 | 2024-11-20 | Nutrition & Biosciences USA 4, Inc. | Coating compositions comprising rubber and insoluble alpha-glucan |
| CN117257695B (zh) * | 2022-12-11 | 2025-10-17 | 麦吉丽生物科技有限公司 | 发酵水油双层组合物及其制备方法与应用 |
| CN116656505B (zh) * | 2023-04-23 | 2024-04-16 | 四川大学 | 一种高产醇脱氢酶和酰基转移酶菌株及培养方法及应用 |
| WO2025097559A1 (zh) * | 2023-11-08 | 2025-05-15 | 上海凯赛生物技术股份有限公司 | 一种长链二元酸及发酵生产长链二元酸的方法 |
| CN119954637A (zh) * | 2023-11-08 | 2025-05-09 | 上海凯赛生物技术股份有限公司 | 生产长链二元酸的方法及长链二元酸 |
| WO2025207802A1 (en) | 2024-03-27 | 2025-10-02 | Nutrition & Biosciences USA 4, Inc. | Recombinant microbial strains comprising reduced beta-oxidation phenotypes and methods thereof |
| CN119913054A (zh) * | 2025-01-15 | 2025-05-02 | 中国科学院天津工业生物技术研究所 | 一种对香豆酸或对香豆酸衍生物生产水平提高的微生物及其构建方法和应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880741A (en) | 1983-10-06 | 1989-11-14 | Pfizer Inc. | Process for transformation of Yarrowia lipolytica |
| US5071764A (en) | 1983-10-06 | 1991-12-10 | Pfizer Inc. | Process for integrative transformation of yarrowia lipolytica |
| US20040146999A1 (en) | 1997-07-21 | 2004-07-29 | E.I. Du Pont De Nemours And Company | Transformed yeast strains and their use for the production of monoterminal and diterminal aliphatic carboxylates |
| US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| FR2879215B1 (fr) * | 2004-12-15 | 2010-08-20 | Inst Francais Du Petrole | Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica |
| US8846374B2 (en) | 2006-12-12 | 2014-09-30 | E I Du Pont De Nemours And Company | Carotenoid production in a recombinant oleaginous yeast |
| US8323935B2 (en) | 2007-10-03 | 2012-12-04 | E I Du Pont De Nemours And Company | Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production |
| WO2012071439A1 (en) | 2010-11-22 | 2012-05-31 | The Regents Of The University Of California | Host cells and methods for producing diacid compounds |
| US8729298B2 (en) | 2011-03-28 | 2014-05-20 | Cathay Industrial Biotech Ltd. | Method for separation and purification of long-chain diacids |
| MY184871A (en) * | 2011-07-06 | 2021-04-28 | Radici Chimica S P A | Biological methods for preparing a fatty dicarboxylic acid |
| EP2785835A2 (en) * | 2011-11-28 | 2014-10-08 | Solazyme, Inc. | Genetically engineered microbial strains including prototheca lipid pathway genes |
| US8916365B2 (en) * | 2012-04-03 | 2014-12-23 | E I Du Pont De Nemours And Company | Expression of cytosolic malic enzyme in transgenic Yarrowia to increase lipid production |
| US9909153B2 (en) * | 2012-11-09 | 2018-03-06 | Calysta, Inc. | Compositions and methods for biological production of fatty acid derivatives |
| JP2016501040A (ja) * | 2012-12-19 | 2016-01-18 | ヴェルデザイン,インコーポレーテッド | 脂肪族ジカルボン酸を調製するための生物学的方法 |
| CA2892516A1 (en) | 2012-12-21 | 2014-06-26 | E. I. Du Pont De Nemours And Company | Down-regulation of a polynucleotide encoding a sou2 sorbitol utilization protein to modify lipid production in microbial cells |
| EP2843043A1 (en) * | 2013-08-27 | 2015-03-04 | Evonik Industries AG | A method for producing acyl amino acids |
-
2016
- 2016-07-20 JP JP2018502751A patent/JP6898915B2/ja not_active Expired - Fee Related
- 2016-07-20 MY MYPI2018700157A patent/MY191314A/en unknown
- 2016-07-20 EP EP16747664.7A patent/EP3325607A1/en not_active Withdrawn
- 2016-07-20 WO PCT/US2016/043133 patent/WO2017015368A1/en not_active Ceased
- 2016-07-20 US US15/746,094 patent/US10626424B2/en not_active Expired - Fee Related
- 2016-07-20 CN CN201680055065.3A patent/CN108138121B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20190144897A1 (en) | 2019-05-16 |
| WO2017015368A1 (en) | 2017-01-26 |
| CN108138121A (zh) | 2018-06-08 |
| US10626424B2 (en) | 2020-04-21 |
| CN108138121B (zh) | 2022-04-19 |
| EP3325607A1 (en) | 2018-05-30 |
| JP6898915B2 (ja) | 2021-07-07 |
| JP2018519843A (ja) | 2018-07-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY191314A (en) | High level production of long-chain dicarboxylic acids with microbes | |
| Gong et al. | Metabolic engineering of microorganisms to produce omega-3 very long-chain polyunsaturated fatty acids | |
| ZA202102053B (en) | Genetically engineered bacterium comprising energy-generating fermentation pathway | |
| SA515360638B1 (ar) | طرق بيولوجية لتحضير حمض دهني ثنائي الكربوكسيل | |
| SG10201810439SA (en) | Production of long chain polyunsaturated fatty acids in plant cells | |
| WO2015010103A3 (en) | Microorganisms and methods for the production of fatty acids and fatty acid derived products | |
| MX2015001780A (es) | Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos. | |
| PH12012502267A1 (en) | Production od dha and other lc-pufas in plants | |
| PH12016501194A1 (en) | Lipid comprising long chain polyunsaturated fatty acids | |
| WO2013075116A3 (en) | Omega 7 rich compositions and methods of isolating omega 7 fatty acids | |
| BR112015031233A2 (pt) | métodos de produção de derivados de ácidos graxos omega-hidroxilados | |
| MX383750B (es) | Método para el cultivo de akkermansia | |
| NZ743288A (en) | Beverage that contains microbial cells | |
| MX390738B (es) | Metodo para producir plantas de genoma modificado a partir de protoplastos de planta a alta eficiencia. | |
| UA117935C2 (uk) | Спосіб одержання l-амінокислот | |
| MX336787B (es) | Microorganismos deseñados geneticamente que comprenden 4-hidroxibenzoil-coa tioesterasas y metodos de uso de los mismos para producir acidos grasos libes y derivados de acidos grasos. | |
| MY198780A (en) | Process for the biological production of methacrylic acid and derivatives thereof | |
| MX2018004507A (es) | Fermentacion. | |
| WO2016104814A3 (en) | Method for producing dicarboxylic acid | |
| WO2017115322A3 (en) | Partial enzymatic hydrolysis of triacylglycerols | |
| MX2016006675A (es) | Producción de ácidos grasos poliinsaturados de cadena larga omega 3 en los cultivos de oleaginosas por una sintasa de pufa proveniente de traustoquitridio. | |
| WO2012031166A3 (en) | Expression of steady state metabolic pathways | |
| MX2016015380A (es) | Produccion biotecnologica de acidos carboxilicos funcionalizados en la posicion ? y esteres de los mismos. | |
| PL410898A1 (pl) | Sposób otrzymywania estrów kwasu mlekowego i mleczanomlekowego w reakcji alkoholizy poliestru alifatycznego | |
| WO2017055932A3 (en) | Improved propionibacterium strains for the production of propionic acid |