MY112110A - Novel 1,2,4-triazolo [1,5 a] pyrimidine compounds, their pharmaceutical compositions and use in the treatment of neurological disorders,and processes for their preparation. - Google Patents
Novel 1,2,4-triazolo [1,5 a] pyrimidine compounds, their pharmaceutical compositions and use in the treatment of neurological disorders,and processes for their preparation.Info
- Publication number
- MY112110A MY112110A MYPI94002724A MYPI19942724A MY112110A MY 112110 A MY112110 A MY 112110A MY PI94002724 A MYPI94002724 A MY PI94002724A MY PI19942724 A MYPI19942724 A MY PI19942724A MY 112110 A MY112110 A MY 112110A
- Authority
- MY
- Malaysia
- Prior art keywords
- 6alkyl
- halo
- cyano
- hydroxy
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939321162A GB9321162D0 (en) | 1993-10-13 | 1993-10-13 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY112110A true MY112110A (en) | 2001-04-30 |
Family
ID=10743505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI94002724A MY112110A (en) | 1993-10-13 | 1994-10-13 | Novel 1,2,4-triazolo [1,5 a] pyrimidine compounds, their pharmaceutical compositions and use in the treatment of neurological disorders,and processes for their preparation. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US5753665A (forum.php) |
| EP (1) | EP0723546B1 (forum.php) |
| JP (1) | JPH09503771A (forum.php) |
| CN (1) | CN1040537C (forum.php) |
| AT (1) | ATE188966T1 (forum.php) |
| AU (1) | AU679573B2 (forum.php) |
| BG (1) | BG62405B1 (forum.php) |
| BR (1) | BR9407812A (forum.php) |
| CA (1) | CA2173857A1 (forum.php) |
| CZ (1) | CZ106996A3 (forum.php) |
| DE (1) | DE69422724T2 (forum.php) |
| DK (1) | DK0723546T3 (forum.php) |
| ES (1) | ES2142413T3 (forum.php) |
| FI (1) | FI961630A0 (forum.php) |
| GB (1) | GB9321162D0 (forum.php) |
| GR (1) | GR3032480T3 (forum.php) |
| HU (1) | HUT74580A (forum.php) |
| IL (1) | IL111259A (forum.php) |
| IN (1) | IN179169B (forum.php) |
| MY (1) | MY112110A (forum.php) |
| NO (1) | NO306509B1 (forum.php) |
| NZ (1) | NZ274500A (forum.php) |
| PL (1) | PL177920B1 (forum.php) |
| PT (1) | PT723546E (forum.php) |
| RO (1) | RO117020B1 (forum.php) |
| RU (1) | RU2136684C1 (forum.php) |
| SK (1) | SK282329B6 (forum.php) |
| TW (1) | TW372237B (forum.php) |
| UA (1) | UA42738C2 (forum.php) |
| WO (1) | WO1995010521A1 (forum.php) |
| ZA (1) | ZA947949B (forum.php) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9506382D0 (en) * | 1995-03-29 | 1995-05-17 | Boots Co Plc | Pharmaceutical compositions |
| GB9507348D0 (en) * | 1995-04-08 | 1995-05-31 | Knoll Ag | Therapeutic agents |
| US5714607A (en) * | 1995-12-01 | 1998-02-03 | American Cyanamid Company | Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide |
| EA002436B1 (ru) * | 1996-07-25 | 2002-04-25 | Мерк Шарп Энд Домэ Лимитед | Замещенные производные триазоло-пиридазина в качестве лигандов рецепторов гамк |
| GB9617727D0 (en) | 1996-08-23 | 1996-10-02 | Knoll Ag | Process |
| GB9626746D0 (en) * | 1996-12-23 | 1997-02-12 | Knoll Ag | Process |
| DE19706336A1 (de) * | 1997-02-19 | 1998-08-20 | Basf Ag | Verfahren zur Herstellung von enantiomerenreinen Alkoholen |
| DE19706337A1 (de) * | 1997-02-19 | 1998-08-20 | Basf Ag | Verfahren zur Herstellung von enantiomerenreinen Estern |
| DE19707008A1 (de) | 1997-02-21 | 1998-08-27 | Basf Ag | Verfahren zur Herstellung von enantiomerenreinen Alkoholen |
| DE69936998T2 (de) | 1998-10-16 | 2008-05-21 | Merck Sharp & Dohme Ltd., Hoddesdon | Pyrazolotriazinderivate als gaba-rezeptorliganden |
| GB9906130D0 (en) * | 1999-03-18 | 1999-05-12 | Knoll Ag | Compounds for use in therapy |
| GB9906126D0 (en) * | 1999-03-18 | 1999-05-12 | Knoll Ag | Pharmaceutical formulations |
| GB9906124D0 (en) * | 1999-03-18 | 1999-05-12 | Knoll Ag | Therapeutic agent |
| GB9914743D0 (en) * | 1999-06-24 | 1999-08-25 | Knoll Ag | Therapeutic agents |
| NZ523807A (en) * | 2000-06-30 | 2004-09-24 | Wyeth Corp | Substituted-triazolopyrimidines as anticancer agents |
| TWI334868B (en) * | 2003-06-03 | 2010-12-21 | Nippon Kayaku Kk | [1,2,4] triazoro [1,5-a] pyrimidine-2-ylurea derivative and use thereof |
| KR100783255B1 (ko) | 2004-02-13 | 2007-12-06 | 워너-램버트 캄파니 엘엘씨 | 안드로젠 수용체 조절제 |
| BRPI0509759A (pt) | 2004-04-13 | 2007-10-16 | Warner Lambert Co | moduladores de androgênio |
| CA2562672C (en) | 2004-04-22 | 2009-09-29 | Warner-Lambert Company Llc | 4-cyano-phenoxy derivatives as androgen modulators |
| TW200724139A (en) | 2005-05-05 | 2007-07-01 | Warner Lambert Co | Androgen modulators |
| BRPI0912928A2 (pt) | 2008-08-29 | 2015-08-04 | Concert Pharmaceuticals Inc | "composto, e, composição isenta de pirogênio" |
| WO2010112485A1 (en) | 2009-04-01 | 2010-10-07 | Neurosearch A/S | SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS |
| US20120095025A1 (en) * | 2009-04-01 | 2012-04-19 | Neurosearch A/S | SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS |
| US8765770B2 (en) | 2009-04-01 | 2014-07-01 | Ataxion, Inc. | Substituted [1,2,4]triazolo[1,5-a]pyrimidines and their use as potassium channel modulators |
| CN113874377A (zh) | 2019-05-13 | 2021-12-31 | 埃科莱布美国股份有限公司 | 作为铜腐蚀抑制剂的1,2,4-三唑并[1,5-a]嘧啶衍生物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE46306B1 (en) * | 1977-02-11 | 1983-05-04 | Ici Ltd | Safeguarded toxic chemical compositions containing an emetic |
| FR2549834B1 (fr) * | 1983-07-25 | 1985-10-18 | Sanofi Sa | Derives de triazolo-pyrimidine, leur procede de preparation et leur application therapeutique en tant que tonicardiaques |
| WO1989001478A1 (en) * | 1987-08-07 | 1989-02-23 | The Australian National University | ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES |
| US5387747A (en) * | 1992-02-24 | 1995-02-07 | Laboratoires Upsa | Triazolopyrimidine derivatives which are angiotensin II receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present |
-
1993
- 1993-10-13 GB GB939321162A patent/GB9321162D0/en active Pending
-
1994
- 1994-10-11 IN IN982MA1994 patent/IN179169B/en unknown
- 1994-10-12 DK DK94929537T patent/DK0723546T3/da active
- 1994-10-12 JP JP7511287A patent/JPH09503771A/ja not_active Ceased
- 1994-10-12 WO PCT/EP1994/003364 patent/WO1995010521A1/en not_active Application Discontinuation
- 1994-10-12 PL PL94313970A patent/PL177920B1/pl unknown
- 1994-10-12 RU RU96108927A patent/RU2136684C1/ru active
- 1994-10-12 HU HU9600959A patent/HUT74580A/hu unknown
- 1994-10-12 PT PT94929537T patent/PT723546E/pt unknown
- 1994-10-12 CA CA002173857A patent/CA2173857A1/en not_active Abandoned
- 1994-10-12 ZA ZA947949A patent/ZA947949B/xx unknown
- 1994-10-12 BR BR9407812A patent/BR9407812A/pt not_active Application Discontinuation
- 1994-10-12 NZ NZ274500A patent/NZ274500A/en unknown
- 1994-10-12 CN CN94194265A patent/CN1040537C/zh not_active Expired - Fee Related
- 1994-10-12 SK SK437-96A patent/SK282329B6/sk unknown
- 1994-10-12 RO RO96-00795A patent/RO117020B1/ro unknown
- 1994-10-12 UA UA96041428A patent/UA42738C2/uk unknown
- 1994-10-12 ES ES94929537T patent/ES2142413T3/es not_active Expired - Lifetime
- 1994-10-12 US US08/628,662 patent/US5753665A/en not_active Expired - Lifetime
- 1994-10-12 IL IL111259A patent/IL111259A/en not_active IP Right Cessation
- 1994-10-12 AT AT94929537T patent/ATE188966T1/de not_active IP Right Cessation
- 1994-10-12 CZ CZ961069A patent/CZ106996A3/cs unknown
- 1994-10-12 AU AU78554/94A patent/AU679573B2/en not_active Ceased
- 1994-10-12 DE DE69422724T patent/DE69422724T2/de not_active Expired - Lifetime
- 1994-10-12 EP EP94929537A patent/EP0723546B1/en not_active Expired - Lifetime
- 1994-10-13 MY MYPI94002724A patent/MY112110A/en unknown
-
1995
- 1995-04-12 TW TW084103591A patent/TW372237B/zh active
-
1996
- 1996-04-09 BG BG100485A patent/BG62405B1/bg unknown
- 1996-04-11 NO NO961435A patent/NO306509B1/no not_active IP Right Cessation
- 1996-04-12 FI FI961630A patent/FI961630A0/fi unknown
-
2000
- 2000-01-26 GR GR20000400175T patent/GR3032480T3/el not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY112110A (en) | Novel 1,2,4-triazolo [1,5 a] pyrimidine compounds, their pharmaceutical compositions and use in the treatment of neurological disorders,and processes for their preparation. | |
| CA2488167A1 (en) | Prodrugs of excitatory amino acids | |
| GR3031492T3 (en) | 1,4-Disubstituted piperazines for the treatment of disorders of the central nervous system and neuro-endocrine disorders | |
| ES8401443A1 (es) | "un procedimiento para preparar derivados de tetralina". | |
| HUT62262A (en) | Process for producing amide composition and pharmaceutical compositions comprising same as active ingredient | |
| HUT72742A (en) | Novel 3,3-diphenylpropylamines, pharmaceutical compositions containing them and preparation | |
| HUT59109A (en) | Process for producing hydroxymethyl-(methylenecyclopentyl)-purines and -pyrimidines, their pharmaceutically acceptable salts and pharmaceutical compositions comprising same | |
| UA66825C2 (uk) | Азаполіциклічні сполуки, конденсовані з арилом, фармацевтична композиція, спосіб лікування та спосіб зниження нікотинової залежності | |
| PT98358A (pt) | Processo para a preparacao de novos compostos pirazolopiridinicos | |
| MY129473A (en) | 3,3-diarylpropylamines, their use and preparation | |
| EP0353955A3 (en) | Novel compounds | |
| GB9305295D0 (en) | Therapeutic compounds | |
| CA2234319A1 (en) | Fluoro-substituted adamantane derivatives | |
| HU9302933D0 (en) | Heterocyclic compounds | |
| CA2010639A1 (en) | Antiviral tetrahydroimidazo [1,4] benzodiazepin-2-thiones | |
| CA2108356A1 (en) | Antibiotic compounds | |
| RO105807B1 (ro) | Procedeu de preparare a unor agenti terapeutici | |
| IE894039L (en) | Therapeutic agents | |
| PT85869A (en) | Process for preparing amino acid derivative anti-convulsant | |
| MX9707596A (es) | Benzamidas, el uso de las mismas, composiciones que las contienen, para el tratamiento del transtorno neurodegenerativo, y procedimiento para la preparacion del mismo. | |
| ZA891769B (en) | Heterocyclic compounds | |
| MXPA01009384A (es) | Composiciones farmaceuticas que comprenden un derivado de pirimidina y ciclodextrina. | |
| JO1833B1 (en) | Therapeutic agents | |
| MXPA01009385A (es) | Compuestos de triazolopirimidinol y sales de los mismos. |