MXPA05009722A - Inhibidores heterociclicos de cinasa: metodos de uso y sintesis. - Google Patents
Inhibidores heterociclicos de cinasa: metodos de uso y sintesis.Info
- Publication number
- MXPA05009722A MXPA05009722A MXPA05009722A MXPA05009722A MXPA05009722A MX PA05009722 A MXPA05009722 A MX PA05009722A MX PA05009722 A MXPA05009722 A MX PA05009722A MX PA05009722 A MXPA05009722 A MX PA05009722A MX PA05009722 A MXPA05009722 A MX PA05009722A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- independently
- heterocyclyl
- heteroaryl
- halogen
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45345703P | 2003-03-10 | 2003-03-10 | |
| US46091003P | 2003-04-07 | 2003-04-07 | |
| US46302503P | 2003-04-15 | 2003-04-15 | |
| US50271003P | 2003-09-12 | 2003-09-12 | |
| PCT/US2004/007286 WO2004080463A1 (en) | 2003-03-10 | 2004-03-10 | Heterocyclic kinase inhibitors: methods of use and synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05009722A true MXPA05009722A (es) | 2006-03-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05009722A MXPA05009722A (es) | 2003-03-10 | 2004-03-10 | Inhibidores heterociclicos de cinasa: metodos de uso y sintesis. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1601357A4 (https=) |
| JP (1) | JP2006519846A (https=) |
| CA (1) | CA2518398A1 (https=) |
| MX (1) | MXPA05009722A (https=) |
| WO (1) | WO2004080463A1 (https=) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
| MY179032A (en) | 2004-10-25 | 2020-10-26 | Cancer Research Tech Ltd | Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors |
| AU2006239929B2 (en) | 2005-04-22 | 2011-11-03 | Alantos Pharmaceuticals Holding, Inc. | Dipeptidyl peptidase-IV inhibitors |
| JP4976394B2 (ja) * | 2005-08-17 | 2012-07-18 | シェーリング コーポレイション | 新規な高親和性のキノリンベースのキナーゼリガンド |
| WO2007125321A2 (en) | 2006-04-25 | 2007-11-08 | Astex Therapeutics Limited | Purine and deazapurine derivatives as pharmaceutical compounds |
| US7511063B2 (en) * | 2006-08-16 | 2009-03-31 | Schering Corporation | High affinity quinoline-based kinase ligands |
| JP2010510202A (ja) | 2006-11-17 | 2010-04-02 | ファイザー株式会社 | 置換ビシクロカルボキシアミド化合物 |
| AU2007329064C1 (en) | 2006-12-07 | 2013-01-17 | F. Hoffmann-La Roche Ag | 2-Aminoquinolines as 5-HT(5A) receptor antagonists |
| DK2124944T3 (da) | 2007-03-14 | 2012-04-23 | Ranbaxy Lab Ltd | Pyrazolo[3,4-b]pyridinderivater som phosphodiesteraseinhibitorer |
| PE20090717A1 (es) | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
| WO2008150364A1 (en) * | 2007-05-23 | 2008-12-11 | Merck & Co., Inc. | Cyclopropyl pyrrolidine orexin receptor antagonists |
| AU2008288898B2 (en) * | 2007-08-22 | 2014-08-07 | Allergan, Inc. | Therapeutic quinoline and naphthalene derivatives |
| AU2008303602A1 (en) * | 2007-09-27 | 2009-04-02 | F. Hoffmann-La Roche Ag | Quinoline derivatives as 5HT5A receptor antagonists |
| PL2201012T3 (pl) | 2007-10-11 | 2014-11-28 | Astrazeneca Ab | Pochodne pirolo[2,3-d]pirymidyny jako inhibitory kinazy białkowej b |
| JP5441705B2 (ja) | 2007-10-15 | 2014-03-12 | 武田薬品工業株式会社 | アミド化合物およびその用途 |
| CA2704266A1 (en) | 2007-11-02 | 2009-06-11 | Vertex Pharmaceuticals Incorporated | [1h- pyrazolo [3, 4-b] pyridine-4-yl] -phenyle or -pyridin-2-yle derivatives as protein kinase c-theta |
| WO2009095752A1 (en) * | 2008-01-29 | 2009-08-06 | Glenmark Pharmaceuticals, S.A. | Fused pyrazole derivatives as cannabinoid receptor modulators |
| EP2262789A1 (en) * | 2008-03-05 | 2010-12-22 | F. Hoffmann-La Roche AG | 2-aminoquinolines |
| CN101959864A (zh) * | 2008-03-07 | 2011-01-26 | 弗·哈夫曼-拉罗切有限公司 | 2-氨基喹啉衍生物 |
| CA2711247A1 (en) * | 2008-03-07 | 2009-09-11 | F. Hoffmann-La Roche Ag | 2-aminoquinolines |
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-
2004
- 2004-03-10 MX MXPA05009722A patent/MXPA05009722A/es not_active Application Discontinuation
- 2004-03-10 EP EP04719237A patent/EP1601357A4/en not_active Withdrawn
- 2004-03-10 CA CA002518398A patent/CA2518398A1/en not_active Abandoned
- 2004-03-10 JP JP2006507031A patent/JP2006519846A/ja active Pending
- 2004-03-10 WO PCT/US2004/007286 patent/WO2004080463A1/en not_active Ceased
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| Publication number | Publication date |
|---|---|
| JP2006519846A (ja) | 2006-08-31 |
| CA2518398A1 (en) | 2004-09-23 |
| WO2004080463A1 (en) | 2004-09-23 |
| EP1601357A1 (en) | 2005-12-07 |
| EP1601357A4 (en) | 2007-10-03 |
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