MXPA04000340A - FORMULACION LIQUIDA QUE COMPRENDE CETUXIMAB Y eSTER DE aCIDO GRASO DE POLIOXIETILEN SORBITaN. - Google Patents
FORMULACION LIQUIDA QUE COMPRENDE CETUXIMAB Y eSTER DE aCIDO GRASO DE POLIOXIETILEN SORBITaN.Info
- Publication number
- MXPA04000340A MXPA04000340A MXPA04000340A MXPA04000340A MXPA04000340A MX PA04000340 A MXPA04000340 A MX PA04000340A MX PA04000340 A MXPA04000340 A MX PA04000340A MX PA04000340 A MXPA04000340 A MX PA04000340A MX PA04000340 A MXPA04000340 A MX PA04000340A
- Authority
- MX
- Mexico
- Prior art keywords
- cetuximab
- fatty acid
- acid ester
- polyoxyethylene sorbitan
- liquid formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Abstract
La invencion se relaciona con una formulacion farmaceutica liquida estable que comprende Cetuximab(r), un anticuerpo monoclonal quimerico contra el receptor del factor de crecimiento endotelial (receptor EGF). La formulacion tiene una mayor estabilidad de almacenamiento y puede usarse por via parenteral para el tratamiento de tumores.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10133394A DE10133394A1 (de) | 2001-07-13 | 2001-07-13 | Flüssige Formulierung enthaltend Cetuximab |
PCT/EP2002/006696 WO2003007988A1 (de) | 2001-07-13 | 2002-06-18 | Flüssige formulierung enthaltend cetuximab und einen polyoxyethylensorbitanfettsäureester |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04000340A true MXPA04000340A (es) | 2004-05-04 |
Family
ID=7691220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04000340A MXPA04000340A (es) | 2001-07-13 | 2002-06-18 | FORMULACION LIQUIDA QUE COMPRENDE CETUXIMAB Y eSTER DE aCIDO GRASO DE POLIOXIETILEN SORBITaN. |
Country Status (18)
Country | Link |
---|---|
US (1) | US20040170632A1 (es) |
EP (1) | EP1406658A1 (es) |
JP (1) | JP2004536129A (es) |
KR (1) | KR20040018458A (es) |
CN (1) | CN1231264C (es) |
AR (1) | AR039358A1 (es) |
BR (1) | BR0211060A (es) |
CA (1) | CA2453342A1 (es) |
CZ (1) | CZ2004189A3 (es) |
DE (1) | DE10133394A1 (es) |
HU (1) | HUP0401046A3 (es) |
MX (1) | MXPA04000340A (es) |
PE (1) | PE20030433A1 (es) |
PL (1) | PL364599A1 (es) |
RU (1) | RU2004102395A (es) |
SK (1) | SK862004A3 (es) |
WO (1) | WO2003007988A1 (es) |
ZA (1) | ZA200401161B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK3417875T3 (da) * | 2003-02-10 | 2020-08-31 | Biogen Ma Inc | Immunglobulinformulering og fremgangsmåde til fremstilling deraf |
DE10355251A1 (de) * | 2003-11-26 | 2005-06-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung enthaltend einen Antikörper gegen den EGF-Rezeptor |
DE10355904A1 (de) | 2003-11-29 | 2005-06-30 | Merck Patent Gmbh | Feste Formen von anti-EGFR-Antikörpern |
AU2005211890B2 (en) * | 2004-02-12 | 2011-07-28 | Merck Patent Gmbh | Highly concentrated liquid formulations of anti-EGFR antibodies |
MXPA06012145A (es) * | 2004-04-27 | 2007-01-31 | Wellstat Biologics Corp | Tratamiento del cancer utilizando virus y camptotecinas. |
JP2008519757A (ja) * | 2004-11-12 | 2008-06-12 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 抗egfr抗体の固形物 |
CN101163468A (zh) * | 2005-02-28 | 2008-04-16 | 卫材R&D管理有限公司 | 磺酰胺化合物的新联合用途 |
NZ570381A (en) | 2006-02-09 | 2011-02-25 | Daiichi Sankyo Co Ltd | Anti-cancer pharmaceutical composition |
WO2007128557A1 (en) | 2006-05-03 | 2007-11-15 | Bayer Schering Pharma Aktiengesellschaft | Combination of an anti edb fibronectin domain antibody l19-sip and an anti-egfr antibody |
AU2007307107B2 (en) * | 2006-10-06 | 2011-11-03 | Amgen Inc. | Stable antibody formulations |
TW200833357A (en) * | 2006-10-20 | 2008-08-16 | Amgen Inc | Stable polypeptide formulations |
CN107773755B (zh) * | 2016-08-31 | 2021-06-22 | 上海津曼特生物科技有限公司 | 抗表皮生长因子受体单克隆抗体的注射液制剂 |
WO2018211517A1 (en) | 2017-05-16 | 2018-11-22 | Bhami's Research Laboratory, Pvt. Ltd. | High concentration protein formulations with reduced viscosity |
KR20210024082A (ko) | 2018-06-25 | 2021-03-04 | 제이씨알 파마 가부시키가이샤 | 단백질 함유 수성 액제 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4128089A (en) * | 1988-09-15 | 1990-03-22 | Rorer International (Overseas) Inc. | Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same |
US5945098A (en) * | 1990-02-01 | 1999-08-31 | Baxter International Inc. | Stable intravenously-administrable immune globulin preparation |
US7060808B1 (en) * | 1995-06-07 | 2006-06-13 | Imclone Systems Incorporated | Humanized anti-EGF receptor monoclonal antibody |
JPH11507535A (ja) * | 1995-06-07 | 1999-07-06 | イムクローン システムズ インコーポレイテッド | 腫瘍の成長を抑制する抗体および抗体フラグメント類 |
PT1516628E (pt) * | 1995-07-27 | 2013-09-24 | Genentech Inc | Formulação de proteína liofilizada isotónica estável |
-
2001
- 2001-07-13 DE DE10133394A patent/DE10133394A1/de not_active Withdrawn
-
2002
- 2002-06-18 HU HU0401046A patent/HUP0401046A3/hu unknown
- 2002-06-18 US US10/483,404 patent/US20040170632A1/en not_active Abandoned
- 2002-06-18 BR BR0211060-1A patent/BR0211060A/pt not_active IP Right Cessation
- 2002-06-18 PL PL02364599A patent/PL364599A1/xx unknown
- 2002-06-18 KR KR10-2004-7000530A patent/KR20040018458A/ko not_active Application Discontinuation
- 2002-06-18 WO PCT/EP2002/006696 patent/WO2003007988A1/de not_active Application Discontinuation
- 2002-06-18 CZ CZ2004189A patent/CZ2004189A3/cs unknown
- 2002-06-18 EP EP02751038A patent/EP1406658A1/de not_active Withdrawn
- 2002-06-18 JP JP2003513593A patent/JP2004536129A/ja not_active Withdrawn
- 2002-06-18 MX MXPA04000340A patent/MXPA04000340A/es unknown
- 2002-06-18 SK SK86-2004A patent/SK862004A3/sk not_active Application Discontinuation
- 2002-06-18 RU RU2004102395/15A patent/RU2004102395A/ru not_active Application Discontinuation
- 2002-06-18 CA CA002453342A patent/CA2453342A1/en not_active Abandoned
- 2002-06-18 CN CNB028141059A patent/CN1231264C/zh not_active Expired - Fee Related
- 2002-07-11 PE PE2002000618A patent/PE20030433A1/es not_active Application Discontinuation
- 2002-07-12 AR ARP020102605A patent/AR039358A1/es unknown
-
2004
- 2004-02-12 ZA ZA200401161A patent/ZA200401161B/en unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0401046A2 (en) | 2006-04-28 |
BR0211060A (pt) | 2004-07-20 |
AR039358A1 (es) | 2005-02-16 |
KR20040018458A (ko) | 2004-03-03 |
HUP0401046A3 (en) | 2006-11-28 |
DE10133394A1 (de) | 2003-01-30 |
CA2453342A1 (en) | 2003-01-30 |
EP1406658A1 (de) | 2004-04-14 |
SK862004A3 (en) | 2004-07-07 |
PL364599A1 (en) | 2004-12-13 |
ZA200401161B (en) | 2004-10-22 |
US20040170632A1 (en) | 2004-09-02 |
WO2003007988A1 (de) | 2003-01-30 |
CN1527724A (zh) | 2004-09-08 |
JP2004536129A (ja) | 2004-12-02 |
CZ2004189A3 (cs) | 2004-05-12 |
PE20030433A1 (es) | 2003-05-24 |
RU2004102395A (ru) | 2005-05-27 |
CN1231264C (zh) | 2005-12-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA04000340A (es) | FORMULACION LIQUIDA QUE COMPRENDE CETUXIMAB Y eSTER DE aCIDO GRASO DE POLIOXIETILEN SORBITaN. | |
MY139055A (en) | Lyophilised preparation containing antibodies to the egf receptor | |
IL178474A0 (en) | Monoclonal antibodies to hepatocyte growth factor and pharmaceutical compositions containing the same | |
PT1412384E (pt) | Formulação estável de glp-1 modificado | |
AU2001231763A1 (en) | Dosing regimen | |
MY145042A (en) | Humanized monoclonal antibodies to hepatocyte growth factor | |
TR200102648T2 (tr) | Büyümeyi destekleyen bileşimler | |
AU2000233235A1 (en) | Use of interleukin-6 antagonists for the treatment of diseases characterised by high levels of aromatase | |
TNSN08511A1 (en) | Lyophilized formulations of anti-egfr antibodies | |
JO3449B1 (ar) | صيغ مستقرة تحتوي على الأجسام المضادة لمضاد عامل نمو الأعصاب | |
JO3000B1 (ar) | مركبات أجسام مضادة . | |
IL214325A (en) | Antibody against cmet, a drug that includes and uses it | |
MY129150A (en) | Novel sulfamides | |
MXPA02010648A (es) | Formulaciones liquidas. | |
TW200736277A (en) | RANKL antibody-PTH/PTHrP chimeric molecules | |
AU2002359727A1 (en) | Fused cyclic modulators of nuclear hormone receptor function | |
WO2005000194A3 (en) | Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same | |
UA37259C2 (uk) | Активна речовина для одержання лікарських засобів при лікуванні дисфункціональних маткових кровотеч | |
EP1755388A4 (en) | MIXED CO-CRYSTALS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | |
AP2003002716A0 (en) | Medicinal compositions containing propenone derivatives. | |
AU2003205768A1 (en) | Methods and compositions for treating hyperproliferative conditions | |
WO2003010291A3 (en) | Treatment of immune disorders and b cell disorders | |
AU2001234273A1 (en) | Thiazolopyrimidines and their use as modulators of chemokine receptor activity | |
AP1696A (en) | Agrochemical formulations comprising ALS inhibitors. | |
MXPA03011059A (es) | Procedimiento para dosificar un combustible con un aditivo de combustible. |