BR0211060A - Formulação lìquida compreendendo cetuximab e um éster de ácido graxo de polioxietileno sorbitano - Google Patents
Formulação lìquida compreendendo cetuximab e um éster de ácido graxo de polioxietileno sorbitanoInfo
- Publication number
- BR0211060A BR0211060A BR0211060-1A BR0211060A BR0211060A BR 0211060 A BR0211060 A BR 0211060A BR 0211060 A BR0211060 A BR 0211060A BR 0211060 A BR0211060 A BR 0211060A
- Authority
- BR
- Brazil
- Prior art keywords
- cetuximab
- fatty acid
- acid ester
- polyoxyethylene sorbitan
- sorbitan fatty
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10133394A DE10133394A1 (de) | 2001-07-13 | 2001-07-13 | Flüssige Formulierung enthaltend Cetuximab |
| PCT/EP2002/006696 WO2003007988A1 (de) | 2001-07-13 | 2002-06-18 | Flüssige formulierung enthaltend cetuximab und einen polyoxyethylensorbitanfettsäureester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0211060A true BR0211060A (pt) | 2004-07-20 |
Family
ID=7691220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0211060-1A BR0211060A (pt) | 2001-07-13 | 2002-06-18 | Formulação lìquida compreendendo cetuximab e um éster de ácido graxo de polioxietileno sorbitano |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20040170632A1 (es) |
| EP (1) | EP1406658A1 (es) |
| JP (1) | JP2004536129A (es) |
| KR (1) | KR20040018458A (es) |
| CN (1) | CN1231264C (es) |
| AR (1) | AR039358A1 (es) |
| BR (1) | BR0211060A (es) |
| CA (1) | CA2453342A1 (es) |
| CZ (1) | CZ2004189A3 (es) |
| DE (1) | DE10133394A1 (es) |
| HU (1) | HUP0401046A3 (es) |
| MX (1) | MXPA04000340A (es) |
| PE (1) | PE20030433A1 (es) |
| PL (1) | PL364599A1 (es) |
| RU (1) | RU2004102395A (es) |
| SK (1) | SK862004A3 (es) |
| WO (1) | WO2003007988A1 (es) |
| ZA (1) | ZA200401161B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05008409A (es) | 2003-02-10 | 2005-10-05 | Elan Pharm Inc | Formulacion de inmunoglobulina y metodo para la preparacion de la misma. |
| DE10355251A1 (de) * | 2003-11-26 | 2005-06-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung enthaltend einen Antikörper gegen den EGF-Rezeptor |
| DE10355904A1 (de) | 2003-11-29 | 2005-06-30 | Merck Patent Gmbh | Feste Formen von anti-EGFR-Antikörpern |
| RU2390353C2 (ru) * | 2004-02-12 | 2010-05-27 | Мерк Патент Гмбх | Высококонцентрированные жидкие композиции анти-egfr антител |
| WO2005113018A2 (en) * | 2004-04-27 | 2005-12-01 | Wellstat Biologics Corporation | Cancer treatment using viruses and camptothecins |
| JP2008519757A (ja) * | 2004-11-12 | 2008-06-12 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 抗ｅｇｆｒ抗体の固形物 |
| WO2006090930A1 (ja) * | 2005-02-28 | 2006-08-31 | Eisai R & D Management Co., Ltd. | スルホンアミド化合物の新規併用 |
| CN101415422B (zh) | 2006-02-09 | 2012-11-07 | 第一三共株式会社 | 抗癌药用组合物 |
| WO2007128557A1 (en) | 2006-05-03 | 2007-11-15 | Bayer Schering Pharma Aktiengesellschaft | Combination of an anti edb fibronectin domain antibody l19-sip and an anti-egfr antibody |
| MX2009003635A (es) * | 2006-10-06 | 2009-04-22 | Amgen Inc | Formulaciones de anticuerpos estables. |
| US7705132B2 (en) * | 2006-10-20 | 2010-04-27 | Amgen Inc. | Stable polypeptide formulations |
| CN107773755B (zh) * | 2016-08-31 | 2021-06-22 | 上海津曼特生物科技有限公司 | 抗表皮生长因子受体单克隆抗体的注射液制剂 |
| SG11202003754YA (en) | 2017-05-16 | 2020-05-28 | Bhamis Research Laboratory Pvt Ltd | High concentration protein formulations with reduced viscosity |
| CN112566652A (zh) | 2018-06-25 | 2021-03-26 | Jcr制药股份有限公司 | 含有蛋白的水性液体制剂 |
| KR20210088528A (ko) * | 2018-08-31 | 2021-07-14 | 앰플릭스 파마슈티컬스, 인크. | 진균 감염을 치료하기 위한 화합물 및 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4128089A (en) * | 1988-09-15 | 1990-03-22 | Rorer International (Overseas) Inc. | Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same |
| US5945098A (en) * | 1990-02-01 | 1999-08-31 | Baxter International Inc. | Stable intravenously-administrable immune globulin preparation |
| US7060808B1 (en) * | 1995-06-07 | 2006-06-13 | Imclone Systems Incorporated | Humanized anti-EGF receptor monoclonal antibody |
| EP0831880A4 (en) * | 1995-06-07 | 2004-12-01 | Imclone Systems Inc | ANTIBODIES AND FRAGMENTS OF ANTIBODIES INHIBITING TUMOR GROWTH |
| CN102416176A (zh) * | 1995-07-27 | 2012-04-18 | 基因技术股份有限公司 | 稳定等渗的冻干蛋白质制剂 |
-
2001
- 2001-07-13 DE DE10133394A patent/DE10133394A1/de not_active Withdrawn
-
2002
- 2002-06-18 MX MXPA04000340A patent/MXPA04000340A/es unknown
- 2002-06-18 CA CA002453342A patent/CA2453342A1/en not_active Abandoned
- 2002-06-18 BR BR0211060-1A patent/BR0211060A/pt not_active IP Right Cessation
- 2002-06-18 PL PL02364599A patent/PL364599A1/xx unknown
- 2002-06-18 JP JP2003513593A patent/JP2004536129A/ja not_active Withdrawn
- 2002-06-18 WO PCT/EP2002/006696 patent/WO2003007988A1/de not_active Application Discontinuation
- 2002-06-18 SK SK86-2004A patent/SK862004A3/sk not_active Application Discontinuation
- 2002-06-18 RU RU2004102395/15A patent/RU2004102395A/ru not_active Application Discontinuation
- 2002-06-18 US US10/483,404 patent/US20040170632A1/en not_active Abandoned
- 2002-06-18 HU HU0401046A patent/HUP0401046A3/hu unknown
- 2002-06-18 CZ CZ2004189A patent/CZ2004189A3/cs unknown
- 2002-06-18 KR KR10-2004-7000530A patent/KR20040018458A/ko not_active Application Discontinuation
- 2002-06-18 EP EP02751038A patent/EP1406658A1/de not_active Withdrawn
- 2002-06-18 CN CNB028141059A patent/CN1231264C/zh not_active Expired - Fee Related
- 2002-07-11 PE PE2002000618A patent/PE20030433A1/es not_active Application Discontinuation
- 2002-07-12 AR ARP020102605A patent/AR039358A1/es unknown
-
2004
- 2004-02-12 ZA ZA200401161A patent/ZA200401161B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1527724A (zh) | 2004-09-08 |
| PE20030433A1 (es) | 2003-05-24 |
| CZ2004189A3 (cs) | 2004-05-12 |
| DE10133394A1 (de) | 2003-01-30 |
| WO2003007988A1 (de) | 2003-01-30 |
| MXPA04000340A (es) | 2004-05-04 |
| CA2453342A1 (en) | 2003-01-30 |
| CN1231264C (zh) | 2005-12-14 |
| SK862004A3 (en) | 2004-07-07 |
| US20040170632A1 (en) | 2004-09-02 |
| EP1406658A1 (de) | 2004-04-14 |
| HUP0401046A2 (en) | 2006-04-28 |
| AR039358A1 (es) | 2005-02-16 |
| PL364599A1 (en) | 2004-12-13 |
| JP2004536129A (ja) | 2004-12-02 |
| RU2004102395A (ru) | 2005-05-27 |
| HUP0401046A3 (en) | 2006-11-28 |
| KR20040018458A (ko) | 2004-03-03 |
| ZA200401161B (en) | 2004-10-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0211060A (pt) | Formulação lìquida compreendendo cetuximab e um éster de ácido graxo de polioxietileno sorbitano | |
| BR0215266A (pt) | Preparação liofilizada compreendendo anticorpos contra o receptor de egf | |
| UY27320A1 (es) | Nuevas composiciones farmacéuticas | |
| BRPI0416986A (pt) | preparação farmacêutica compreendendo um anticorpo contra o receptor de egf | |
| ATE464062T1 (de) | Stabilisierte flüssige pharmazeutische zusammensetzung enthaltend tfpi | |
| ATE427925T1 (de) | Phenoxycarbonsaureverbindungen und zusammensetzungen zur verabreichung aktiver wirkstoffe | |
| CO5660273A2 (es) | Formulaciones de proteina y anticuerpo de alta concentracion | |
| SE0100901D0 (sv) | New composition | |
| ATE286500T1 (de) | 1,2,3,4-tetrahydroisochinolin-derivate | |
| DE60236541D1 (de) | Inhibitoren von 11-beta-hydroxysteroiddehydrogenase typ 1 | |
| NO20051102L (no) | Sulfonylamino-eddiksyre-derivater | |
| BR0209777A (pt) | Formulações lìquidas estáveis | |
| PT1263725E (pt) | Novos compostos | |
| PT1311285E (pt) | Composicao farmaceutica liquida contendo um derivado de eritropoietina | |
| WO2004006959A8 (en) | Liquid dosage compositions of stable nanoparticulate active agents | |
| ATE382057T1 (de) | Stabile formulierung von modifiziertem glp-1 | |
| NO20052520L (no) | Nye sulfamider | |
| EA200800731A1 (ru) | Жидкие составы гербицидов на основе сульфонилмочевины | |
| MXPA04004837A (es) | Inhibidores de 11-??-hidroxiesteroide deshidrogenasa de tipo 1. | |
| MXPA04004842A (es) | Inhibidores de 11-(-hidroxiesteroide deshidrogenasa de tipo 1. | |
| DE60037726D1 (de) | Carbonsäurederivate die die bindung von integrinen an ihre rezeptoren hemmen | |
| AP2003002742A0 (en) | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | |
| ATE301654T1 (de) | Naphthyridinderivate | |
| ATE311373T1 (de) | Oxadiazolverbindungen und -zusammensetzungen zur abgabe von wirkstoffen | |
| MY127749A (en) | Liquid formulation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A,6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2029 DE 24/11/2009. |