PE20030433A1 - Formulacion liquida que comprende cetuximab - Google Patents
Formulacion liquida que comprende cetuximabInfo
- Publication number
- PE20030433A1 PE20030433A1 PE2002000618A PE2002000618A PE20030433A1 PE 20030433 A1 PE20030433 A1 PE 20030433A1 PE 2002000618 A PE2002000618 A PE 2002000618A PE 2002000618 A PE2002000618 A PE 2002000618A PE 20030433 A1 PE20030433 A1 PE 20030433A1
- Authority
- PE
- Peru
- Prior art keywords
- liquid formulation
- polyoxyethylene
- formulation including
- including cetuximab
- cetuximab
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Abstract
SE REFIERE A UNA FORMULACION FARMACEUTICA LIQUIDA QUE COMPRENDE: a) EL ANTICUERPO MONOCLONAL QUIMERICO C225 ( CETUXIMAB ) CONTRA EL RECEPTOR DEL FACTOR DE CRECIMIENTO ENDOTELIAL (RECEPTOR EGF) ; b) DE 2mM A 100 mM DE UN BUFFER FOSFATO Y c) DE 0,005% A 0,1% DE UN ESTER DE ACIDO GRASO DE POLIOXIETILEN SORBITAN SELECCIONADO DE MONOOLEATO DE POLIOXIETILEN (20) SORBITAN O MONOLAURATO DE POLIOXIETILEN (20) SORBITAN. LA FORMULACION TIENE UN pH ENTRE 6,5 A 7,5 Y CONTIENE ADEMAS UN AGENTE ISOTONICO TAL COMO CLORURO DE SODIO
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10133394A DE10133394A1 (de) | 2001-07-13 | 2001-07-13 | Flüssige Formulierung enthaltend Cetuximab |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20030433A1 true PE20030433A1 (es) | 2003-05-24 |
Family
ID=7691220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2002000618A PE20030433A1 (es) | 2001-07-13 | 2002-07-11 | Formulacion liquida que comprende cetuximab |
Country Status (18)
Country | Link |
---|---|
US (1) | US20040170632A1 (es) |
EP (1) | EP1406658A1 (es) |
JP (1) | JP2004536129A (es) |
KR (1) | KR20040018458A (es) |
CN (1) | CN1231264C (es) |
AR (1) | AR039358A1 (es) |
BR (1) | BR0211060A (es) |
CA (1) | CA2453342A1 (es) |
CZ (1) | CZ2004189A3 (es) |
DE (1) | DE10133394A1 (es) |
HU (1) | HUP0401046A3 (es) |
MX (1) | MXPA04000340A (es) |
PE (1) | PE20030433A1 (es) |
PL (1) | PL364599A1 (es) |
RU (1) | RU2004102395A (es) |
SK (1) | SK862004A3 (es) |
WO (1) | WO2003007988A1 (es) |
ZA (1) | ZA200401161B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK3417875T3 (da) * | 2003-02-10 | 2020-08-31 | Biogen Ma Inc | Immunglobulinformulering og fremgangsmåde til fremstilling deraf |
DE10355251A1 (de) * | 2003-11-26 | 2005-06-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung enthaltend einen Antikörper gegen den EGF-Rezeptor |
DE10355904A1 (de) | 2003-11-29 | 2005-06-30 | Merck Patent Gmbh | Feste Formen von anti-EGFR-Antikörpern |
AU2005211890B2 (en) * | 2004-02-12 | 2011-07-28 | Merck Patent Gmbh | Highly concentrated liquid formulations of anti-EGFR antibodies |
MXPA06012145A (es) * | 2004-04-27 | 2007-01-31 | Wellstat Biologics Corp | Tratamiento del cancer utilizando virus y camptotecinas. |
JP2008519757A (ja) * | 2004-11-12 | 2008-06-12 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 抗egfr抗体の固形物 |
CN101163468A (zh) * | 2005-02-28 | 2008-04-16 | 卫材R&D管理有限公司 | 磺酰胺化合物的新联合用途 |
NZ570381A (en) | 2006-02-09 | 2011-02-25 | Daiichi Sankyo Co Ltd | Anti-cancer pharmaceutical composition |
WO2007128557A1 (en) | 2006-05-03 | 2007-11-15 | Bayer Schering Pharma Aktiengesellschaft | Combination of an anti edb fibronectin domain antibody l19-sip and an anti-egfr antibody |
AU2007307107B2 (en) * | 2006-10-06 | 2011-11-03 | Amgen Inc. | Stable antibody formulations |
TW200833357A (en) * | 2006-10-20 | 2008-08-16 | Amgen Inc | Stable polypeptide formulations |
CN107773755B (zh) * | 2016-08-31 | 2021-06-22 | 上海津曼特生物科技有限公司 | 抗表皮生长因子受体单克隆抗体的注射液制剂 |
WO2018211517A1 (en) | 2017-05-16 | 2018-11-22 | Bhami's Research Laboratory, Pvt. Ltd. | High concentration protein formulations with reduced viscosity |
KR20210024082A (ko) | 2018-06-25 | 2021-03-04 | 제이씨알 파마 가부시키가이샤 | 단백질 함유 수성 액제 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4128089A (en) * | 1988-09-15 | 1990-03-22 | Rorer International (Overseas) Inc. | Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same |
US5945098A (en) * | 1990-02-01 | 1999-08-31 | Baxter International Inc. | Stable intravenously-administrable immune globulin preparation |
US7060808B1 (en) * | 1995-06-07 | 2006-06-13 | Imclone Systems Incorporated | Humanized anti-EGF receptor monoclonal antibody |
JPH11507535A (ja) * | 1995-06-07 | 1999-07-06 | イムクローン システムズ インコーポレイテッド | 腫瘍の成長を抑制する抗体および抗体フラグメント類 |
PT1516628E (pt) * | 1995-07-27 | 2013-09-24 | Genentech Inc | Formulação de proteína liofilizada isotónica estável |
-
2001
- 2001-07-13 DE DE10133394A patent/DE10133394A1/de not_active Withdrawn
-
2002
- 2002-06-18 HU HU0401046A patent/HUP0401046A3/hu unknown
- 2002-06-18 US US10/483,404 patent/US20040170632A1/en not_active Abandoned
- 2002-06-18 BR BR0211060-1A patent/BR0211060A/pt not_active IP Right Cessation
- 2002-06-18 PL PL02364599A patent/PL364599A1/xx unknown
- 2002-06-18 KR KR10-2004-7000530A patent/KR20040018458A/ko not_active Application Discontinuation
- 2002-06-18 WO PCT/EP2002/006696 patent/WO2003007988A1/de not_active Application Discontinuation
- 2002-06-18 CZ CZ2004189A patent/CZ2004189A3/cs unknown
- 2002-06-18 EP EP02751038A patent/EP1406658A1/de not_active Withdrawn
- 2002-06-18 JP JP2003513593A patent/JP2004536129A/ja not_active Withdrawn
- 2002-06-18 MX MXPA04000340A patent/MXPA04000340A/es unknown
- 2002-06-18 SK SK86-2004A patent/SK862004A3/sk not_active Application Discontinuation
- 2002-06-18 RU RU2004102395/15A patent/RU2004102395A/ru not_active Application Discontinuation
- 2002-06-18 CA CA002453342A patent/CA2453342A1/en not_active Abandoned
- 2002-06-18 CN CNB028141059A patent/CN1231264C/zh not_active Expired - Fee Related
- 2002-07-11 PE PE2002000618A patent/PE20030433A1/es not_active Application Discontinuation
- 2002-07-12 AR ARP020102605A patent/AR039358A1/es unknown
-
2004
- 2004-02-12 ZA ZA200401161A patent/ZA200401161B/en unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0401046A2 (en) | 2006-04-28 |
BR0211060A (pt) | 2004-07-20 |
MXPA04000340A (es) | 2004-05-04 |
AR039358A1 (es) | 2005-02-16 |
KR20040018458A (ko) | 2004-03-03 |
HUP0401046A3 (en) | 2006-11-28 |
DE10133394A1 (de) | 2003-01-30 |
CA2453342A1 (en) | 2003-01-30 |
EP1406658A1 (de) | 2004-04-14 |
SK862004A3 (en) | 2004-07-07 |
PL364599A1 (en) | 2004-12-13 |
ZA200401161B (en) | 2004-10-22 |
US20040170632A1 (en) | 2004-09-02 |
WO2003007988A1 (de) | 2003-01-30 |
CN1527724A (zh) | 2004-09-08 |
JP2004536129A (ja) | 2004-12-02 |
CZ2004189A3 (cs) | 2004-05-12 |
RU2004102395A (ru) | 2005-05-27 |
CN1231264C (zh) | 2005-12-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20030433A1 (es) | Formulacion liquida que comprende cetuximab | |
PE20090738A1 (es) | Formulaciones de anticuerpos | |
AU3438900A (en) | Use of trehalose for stabilising a liquid vaccine | |
CO5660273A2 (es) | Formulaciones de proteina y anticuerpo de alta concentracion | |
MA27551A1 (fr) | Composition immunogene | |
JO2481B1 (en) | Silo cano-indol compounds have fluoride substitution and formulations containing such compounds and their treatment methods | |
IL153406A0 (en) | Cyclopentanoindoles, compositions containing such compounds and methods of treatment | |
UY26704A1 (es) | Nueva composición farmacéutica | |
MX275023B (es) | Champu que contiene una red de gel. | |
ATE485835T1 (de) | Antikörper enthaltende pharmazeutische lösungen | |
ES2143507T3 (es) | Vacunas contra la enfermedad de aujeszky y de otras enfermedades animales que contienen mutantes del virus de la pseudorrabia. | |
NL980012I2 (nl) | Mometasonfuroaat-monohydraat, werkwijze om zulks te bereiden en farmaceutische samenstellingen. | |
ES2194989T3 (es) | Composicion adminstrada por via oral, que comprende una toxina de zonula occludens y un agente que tiene una actividad biologica, y su utilizacion. | |
NO20014101L (no) | Stabilisert oral farmasöytisk blanding inneholdende iodid og iodat og fremgangsmåte | |
AU2019339740A8 (en) | CSF-1R antibody formulation | |
CL2009001680A1 (es) | Composiciones agroquimicas que comprenden a)metconazol o una sal del mismo y b)un acido carboxilico alifatico de cadena lineal o ramificada, saturado o no saturado y donde la relacion molar de (b) respecto de (a) es superior a 1 | |
ES2182255T3 (es) | Agente de blanqueo fluorescente. | |
MX2021010951A (es) | Composición líquida que comprende un anticuerpo del receptor alfa de interleucina-4 humano. | |
CA2498233A1 (en) | Clear ophthalmic solution comprising latanoprost as active ingredient | |
ATE502647T1 (de) | Zubereitungen enthaltend sincalide | |
BRPI0017528B8 (pt) | uso de uma composição contendo sal de cetotifeno | |
EP1509250A4 (en) | METHOD, COMPOSITIONS AND PRODUCTION OBJECTS FOR MODULATING BONE GROWTH | |
BR0304218A (pt) | ésteres alicìclicos com fragrância de almìscar | |
WO2007006581A3 (en) | Targeting lsd1 for use in identifying and/or scoring prostate cancer and for controlling anrogen receptor-dependent gene expression | |
HUP0300240A2 (hu) | Polikarbonáttartalmú készítmények |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application declared void or lapsed |