MXPA03004884A - Ciclohexil (alquil)-propanolaminas, metodo de preparacion y composiciones farmaceuticas que contienen las mismas. - Google Patents
Ciclohexil (alquil)-propanolaminas, metodo de preparacion y composiciones farmaceuticas que contienen las mismas.Info
- Publication number
- MXPA03004884A MXPA03004884A MXPA03004884A MXPA03004884A MXPA03004884A MX PA03004884 A MXPA03004884 A MX PA03004884A MX PA03004884 A MXPA03004884 A MX PA03004884A MX PA03004884 A MXPA03004884 A MX PA03004884A MX PA03004884 A MXPA03004884 A MX PA03004884A
- Authority
- MX
- Mexico
- Prior art keywords
- agents
- formula
- compounds
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Abstract
La invencion se refiere a compuestos de la formula (l), en donde: A es un grupo de la formula (a) o (b), sus sales o solvatos, composiciones farmaceuticas que los contienen, un metodo para prepararlos y compuestos intermedios utilizados en dicho metodo. Los compuestos de la formula (I) pueden prescribirse para tratar enfermedades gastro-intestinales tales como enfermedades inflamatorias del Intestino tal como sindrome de colon irritable (IBD), como moduladores de motricidad intestinal, como Iipoliticos, agentes anti-obesidad, agentes anti-diabeticos, psicotropicos, agentes anti-glaucoma, cicatrizadores, anti-depresores, como inhibidor de contracciones uterinas, como tocoliticos para prevenir o retardar los partos prematuros, para el tratamiento y/o profilaxis de la dismenorrea. Por otro lado, los compuestos de la formula (I) pueden utilizarse en el tratamiento de ciertas enfermedades del sistema nervioso central, tal como, por ejemplo la depresion, asi como ciertos problemas del sistema urinario tal como incontinencia urinaria.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0015477A FR2817257B1 (fr) | 2000-11-30 | 2000-11-30 | Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant |
PCT/FR2001/003784 WO2002044139A1 (fr) | 2000-11-30 | 2001-11-30 | Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03004884A true MXPA03004884A (es) | 2004-05-04 |
Family
ID=8857054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03004884A MXPA03004884A (es) | 2000-11-30 | 2001-11-30 | Ciclohexil (alquil)-propanolaminas, metodo de preparacion y composiciones farmaceuticas que contienen las mismas. |
Country Status (25)
Country | Link |
---|---|
US (3) | US7388031B2 (es) |
EP (1) | EP1341753B1 (es) |
JP (1) | JP4024149B2 (es) |
CN (2) | CN1935787A (es) |
AR (1) | AR031438A1 (es) |
AT (1) | ATE374177T1 (es) |
AU (2) | AU2002222079B2 (es) |
BR (1) | BR0115768A (es) |
CA (1) | CA2429267C (es) |
CY (1) | CY1106997T1 (es) |
CZ (1) | CZ305140B6 (es) |
DE (1) | DE60130676T2 (es) |
DK (1) | DK1341753T3 (es) |
ES (1) | ES2290201T3 (es) |
FR (1) | FR2817257B1 (es) |
HK (1) | HK1055945A1 (es) |
HU (1) | HU229583B1 (es) |
ME (1) | MEP23308A (es) |
MX (1) | MXPA03004884A (es) |
PL (1) | PL206695B1 (es) |
PT (1) | PT1341753E (es) |
RS (1) | RS51571B (es) |
SI (1) | SI1341753T1 (es) |
SK (1) | SK287551B6 (es) |
WO (1) | WO2002044139A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2817257B1 (fr) * | 2000-11-30 | 2009-03-20 | Sanofi Synthelabo | Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant |
FR2840304B1 (fr) * | 2002-05-29 | 2007-05-18 | Sanofi Synthelabo | Derives d'oxophenyl-cyclohexyl-propanolamine, leur preparation et leur application en therapeutique |
FR2840301B1 (fr) * | 2002-05-29 | 2007-03-23 | Sanofi Synthelabo | Derives de phenyl-cyclohexyl-propanolamine, leur preparation et leur applicaton en therapeutique |
EP2011490A1 (en) | 2007-07-05 | 2009-01-07 | Sanofi-Aventis | Beta adrenergic receptor ligand derivatives for modulating apoptosis |
FR2935141B1 (fr) * | 2008-08-21 | 2010-10-08 | Sanofi Aventis | Procede de preparation de l'ester ethylique de l'acide 4-[trans-4-[(phenylmethyl)-amino]cyclohexyl]benzoique et de son sel hemifumarate |
WO2010051503A1 (en) * | 2008-10-31 | 2010-05-06 | Medivation Technologies, Inc. | Azepino [4, 5-b] indoles and methods of use |
CN116143575B (zh) * | 2023-04-21 | 2023-06-30 | 研峰(天津)科学技术应用研究有限公司 | 昆虫信息素原料3-环己基-1-丙炔合成方法 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4004028A (en) * | 1975-08-06 | 1977-01-18 | Smithkline Corporation | Phenoxypropanolamines |
CA1336911C (en) * | 1988-06-03 | 1995-09-05 | David Taiwai Wong | Serotonin antagonists |
US5158956A (en) | 1990-05-04 | 1992-10-27 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with benzodioxanes |
US5340838A (en) | 1990-05-04 | 1994-08-23 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines |
US5096908A (en) | 1990-05-04 | 1992-03-17 | Eli Lilly And Company | Method of inhibiting gastric acid secretion |
US5258379A (en) | 1990-05-04 | 1993-11-02 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with n-arylpiperazines |
DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
IL107611A0 (en) | 1992-11-18 | 1994-02-27 | Smithkline Beecham Corp | Steroid compounds and pharmaceutical compositions containing them |
US5451677A (en) * | 1993-02-09 | 1995-09-19 | Merck & Co., Inc. | Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity |
IL110857A0 (en) | 1993-09-09 | 1994-11-28 | Lilly Co Eli | Cessation of tobacco use |
CA2134038C (en) | 1994-06-16 | 1997-06-03 | David Taiwai Wong | Potentiation of drug response |
EP0714663A3 (en) | 1994-11-28 | 1997-01-15 | Lilly Co Eli | Potentiation of drug responses by serotonin 1A receptor antagonists |
US5776959A (en) | 1995-06-05 | 1998-07-07 | Washington University | Anticonvulsant and anxiolytic lactam and thiolactam derivatives |
IL123677A0 (en) * | 1995-09-21 | 1998-10-30 | Lilly Co Eli | Selective beta3 adrenergic agonists |
EP0792649A1 (en) | 1996-02-29 | 1997-09-03 | Eli Lilly And Company | Treatment of sleep disorders |
US5958429A (en) | 1996-08-16 | 1999-09-28 | Eli Lilly And Company | Potentiation of serotonin response |
US20020019440A1 (en) | 1996-11-05 | 2002-02-14 | Virbac Sa | Aryloxypropanolamine derivatives, method of preparation and applications thereof |
FR2755439B1 (fr) | 1996-11-05 | 1998-12-24 | Virbac Sa | Derives aryloxypropanolamines, leur procede de preparation et leurs applications |
FR2758460B1 (fr) * | 1997-01-21 | 1999-12-31 | Sanofi Sa | Utilisation des agonistes des recepteurs beta-3 adrenergiques pour la preparation de medicaments cicatrisants |
US5776969A (en) | 1997-02-27 | 1998-07-07 | Eli Lilly And Company | Treatment of sleep disorders |
FR2780057B1 (fr) * | 1998-06-18 | 2002-09-13 | Sanofi Sa | Phenoxypropanolamines, procede pour leur preparation et compositions pharmaceutiques les contenant |
JP2000086603A (ja) | 1998-07-15 | 2000-03-28 | Yoshitomi Pharmaceut Ind Ltd | 桂皮酸アミド誘導体および3―フェニルプロピオン酸アミド誘導体 |
AU2400300A (en) | 1998-12-30 | 2000-07-31 | Eli Lilly And Company | Solution phase synthesis of compounds including amine alcohol functionality |
US6248739B1 (en) | 1999-01-08 | 2001-06-19 | Pharmacia & Upjohn Company | Quinolinecarboxamides as antiviral agents |
US20020019940A1 (en) * | 2000-06-16 | 2002-02-14 | Matteson Craig S. | Method and apparatus for assigning test and assessment instruments to users |
AUPQ841300A0 (en) * | 2000-06-27 | 2000-07-20 | Fujisawa Pharmaceutical Co., Ltd. | New aminoalcohol derivatives |
MXPA03000308A (es) | 2000-07-13 | 2003-06-06 | Lilly Co Eli | Agonistas beta3 adrenergicos. |
FR2817257B1 (fr) | 2000-11-30 | 2009-03-20 | Sanofi Synthelabo | Cyclohexyl(alkyl)-propanolamines, leur preparation et compositions pharmaceutiques en contenant |
US6693125B2 (en) | 2001-01-24 | 2004-02-17 | Combinatorx Incorporated | Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders |
FR2840301B1 (fr) | 2002-05-29 | 2007-03-23 | Sanofi Synthelabo | Derives de phenyl-cyclohexyl-propanolamine, leur preparation et leur applicaton en therapeutique |
FR2840304B1 (fr) * | 2002-05-29 | 2007-05-18 | Sanofi Synthelabo | Derives d'oxophenyl-cyclohexyl-propanolamine, leur preparation et leur application en therapeutique |
AU2003251904A1 (en) | 2002-07-15 | 2004-02-02 | Combinatorx, Incorporated | Combinations of drugs for the treatment of neoplasms |
AU2003262947A1 (en) | 2002-08-30 | 2004-03-19 | Pharmacia And Upjohn Company | Method of preventing or treating atherosclerosis or restenosis |
US20070066590A1 (en) | 2003-02-24 | 2007-03-22 | Jones Robert M | Phenyl-and pyridylpiperidine-derivatives as modulators of glucose metabolism |
JP2007528400A (ja) | 2004-03-09 | 2007-10-11 | エラン ファーマシューティカルズ,インコーポレイテッド | 置換ヒドロキシエチルアミン系のアスパラギン酸プロテアーゼ阻害薬 |
-
2000
- 2000-11-30 FR FR0015477A patent/FR2817257B1/fr not_active Expired - Fee Related
-
2001
- 2001-11-29 AR ARP010105555A patent/AR031438A1/es not_active Application Discontinuation
- 2001-11-30 AT AT01998533T patent/ATE374177T1/de active
- 2001-11-30 SI SI200130783T patent/SI1341753T1/sl unknown
- 2001-11-30 BR BR0115768-0A patent/BR0115768A/pt active Search and Examination
- 2001-11-30 PL PL364746A patent/PL206695B1/pl unknown
- 2001-11-30 CZ CZ2003-1499A patent/CZ305140B6/cs not_active IP Right Cessation
- 2001-11-30 CN CNA2006101518761A patent/CN1935787A/zh active Pending
- 2001-11-30 PT PT01998533T patent/PT1341753E/pt unknown
- 2001-11-30 US US10/432,493 patent/US7388031B2/en not_active Expired - Lifetime
- 2001-11-30 WO PCT/FR2001/003784 patent/WO2002044139A1/fr active IP Right Grant
- 2001-11-30 JP JP2002546509A patent/JP4024149B2/ja not_active Expired - Fee Related
- 2001-11-30 ES ES01998533T patent/ES2290201T3/es not_active Expired - Lifetime
- 2001-11-30 CA CA2429267A patent/CA2429267C/fr not_active Expired - Fee Related
- 2001-11-30 DE DE60130676T patent/DE60130676T2/de not_active Expired - Lifetime
- 2001-11-30 CN CNB018198880A patent/CN1283622C/zh not_active Expired - Fee Related
- 2001-11-30 EP EP01998533A patent/EP1341753B1/fr not_active Expired - Lifetime
- 2001-11-30 SK SK652-2003A patent/SK287551B6/sk not_active IP Right Cessation
- 2001-11-30 ME MEP-233/08A patent/MEP23308A/xx unknown
- 2001-11-30 MX MXPA03004884A patent/MXPA03004884A/es active IP Right Grant
- 2001-11-30 AU AU2002222079A patent/AU2002222079B2/en not_active Ceased
- 2001-11-30 DK DK01998533T patent/DK1341753T3/da active
- 2001-11-30 HU HU0400565A patent/HU229583B1/hu not_active IP Right Cessation
- 2001-11-30 AU AU2207902A patent/AU2207902A/xx active Pending
- 2001-11-30 RS YU41703A patent/RS51571B/en unknown
-
2003
- 2003-11-14 HK HK03108328A patent/HK1055945A1/xx not_active IP Right Cessation
-
2006
- 2006-08-15 US US11/464,537 patent/US7419974B2/en not_active Expired - Lifetime
-
2007
- 2007-11-08 CY CY20071101450T patent/CY1106997T1/el unknown
-
2008
- 2008-06-24 US US12/144,843 patent/US7718646B2/en not_active Expired - Lifetime
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Legal Events
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HC | Change of company name or juridical status | ||
FG | Grant or registration |