MXPA03003916A - Proceso para la preparacion de monohidrato de tienamicina de n-formimidoilo cristalino (monohidrato de imipenem). - Google Patents

Proceso para la preparacion de monohidrato de tienamicina de n-formimidoilo cristalino (monohidrato de imipenem).

Info

Publication number
MXPA03003916A
MXPA03003916A MXPA03003916A MXPA03003916A MXPA03003916A MX PA03003916 A MXPA03003916 A MX PA03003916A MX PA03003916 A MXPA03003916 A MX PA03003916A MX PA03003916 A MXPA03003916 A MX PA03003916A MX PA03003916 A MXPA03003916 A MX PA03003916A
Authority
MX
Mexico
Prior art keywords
monohydrate
crystalline
preparation
imipenem
formimidoyl thienamycin
Prior art date
Application number
MXPA03003916A
Other languages
English (en)
Spanish (es)
Inventor
Kumar Yatendra
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11097114&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA03003916(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of MXPA03003916A publication Critical patent/MXPA03003916A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
MXPA03003916A 2000-11-03 2001-11-05 Proceso para la preparacion de monohidrato de tienamicina de n-formimidoilo cristalino (monohidrato de imipenem). MXPA03003916A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN983DE2000 IN191798B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2000-11-03 2000-11-03
PCT/IB2001/002069 WO2002036594A1 (en) 2000-11-03 2001-11-05 Process for the preparation of crystalline n-formimidoyl thienamycin monohydrate (imipenem monohydrate)

Publications (1)

Publication Number Publication Date
MXPA03003916A true MXPA03003916A (es) 2004-01-29

Family

ID=11097114

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03003916A MXPA03003916A (es) 2000-11-03 2001-11-05 Proceso para la preparacion de monohidrato de tienamicina de n-formimidoilo cristalino (monohidrato de imipenem).

Country Status (19)

Country Link
US (1) US7078534B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP1334105B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2004525084A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR20030059812A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN100445284C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE322495T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2002212591A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG107852A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2427762C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE60118593D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK1334105T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EA (1) EA006442B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EE (1) EE200300206A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2261494T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN191798B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MXPA03003916A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT1334105E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2002036594A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA200303338B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK15092003A3 (sk) 2001-05-18 2004-09-08 Ranbaxy Laboratories Limited Spôsob izolácie kryštalického imipenému
EP1395587B1 (en) * 2001-05-18 2009-07-29 Ranbaxy Laboratories Limited Process for the preparation of imipenem
CN1522235A (zh) * 2001-05-18 2004-08-18 ʵ 制备无定形西司他汀钠的方法
US20040198973A1 (en) * 2001-08-13 2004-10-07 Tsujii Masahiko Process for preparation of carbapenem antibiotics
JP2005509037A (ja) 2001-11-16 2005-04-07 ランバクシー ラボラトリーズ リミテッド 結晶イミペネム製造方法
US6537985B1 (en) * 2001-11-30 2003-03-25 Phoenix Scientific, Inc. Antibiotic formulation and a method of making this formulation
MXPA06001115A (es) * 2003-12-09 2006-04-11 Choongwae Pharm Co Un proceso nuevo para la preparacion de imipenem.
KR100848751B1 (ko) * 2006-11-10 2008-07-25 제일약품주식회사 이미페넴의 제조방법
KR100848752B1 (ko) * 2006-11-10 2008-07-25 제일약품주식회사 티에나마이신 용매화합물 및 그의 제조방법
EP2209787A4 (en) * 2007-10-08 2011-08-03 Orchid Chemicals & Pharm Ltd METHOD FOR PRODUCING A CARBAPENEM ANTIBIOTICS
CN108623598A (zh) * 2018-05-21 2018-10-09 重庆天地药业有限责任公司 一种亚胺培南中间体及亚胺培南的制备方法
CN111413427A (zh) * 2020-04-08 2020-07-14 苏州和合医学检验有限公司 超滤前处理高效液相色谱测定血浆中亚胺培南含量的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4194047A (en) 1975-11-21 1980-03-18 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin
US4260543A (en) * 1978-07-03 1981-04-07 Merck & Co., Inc. Crystalline N-formimidoyl thienamycin
JP3048196B2 (ja) 1991-06-20 2000-06-05 第一製薬株式会社 カルバペネム誘導体
ES2101119T3 (es) 1991-10-01 1997-07-01 Procter & Gamble Pharma Procedimiento para preparar quinolonil-lactamas antimicrobianas.
FI104822B (fi) 1992-09-09 2000-04-14 Sankyo Co Menetelmä karbapeneemi- ja peneemiyhdisteiden valmistamiseksi
US5245069A (en) * 1992-10-27 1993-09-14 Merck & Co., Inc. Process for the preparation of bis(aryl)-phosphorohalidates
US5872250A (en) * 1997-07-30 1999-02-16 Merck & Co., Inc. Process for synthesizing carbapenem antibiotics

Also Published As

Publication number Publication date
CA2427762C (en) 2009-10-20
US20040054167A1 (en) 2004-03-18
ATE322495T1 (de) 2006-04-15
US7078534B2 (en) 2006-07-18
EA200300520A1 (ru) 2003-10-30
BG107852A (bg) 2004-01-30
AU2002212591A1 (en) 2002-05-15
PT1334105E (pt) 2006-08-31
EP1334105A1 (en) 2003-08-13
CN1481384A (zh) 2004-03-10
JP2004525084A (ja) 2004-08-19
EE200300206A (et) 2003-10-15
DE60118593D1 (de) 2006-05-18
CA2427762A1 (en) 2002-05-10
KR20030059812A (ko) 2003-07-10
EP1334105B1 (en) 2006-04-05
WO2002036594A1 (en) 2002-05-10
IN191798B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2004-01-03
ZA200303338B (en) 2004-03-09
ES2261494T3 (es) 2006-11-16
CN100445284C (zh) 2008-12-24
DK1334105T3 (da) 2006-08-14
EA006442B1 (ru) 2005-12-29

Similar Documents

Publication Publication Date Title
MXPA03003916A (es) Proceso para la preparacion de monohidrato de tienamicina de n-formimidoilo cristalino (monohidrato de imipenem).
BG107856A (en) Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
MXPA04004604A (es) Proceso para la preparacion de imipenem cristalino.
WO2004013120A8 (en) Novel benzodioxoles
WO2003002530A3 (en) Pyrrolidines as dipeptidyl peptidase inhibitors
WO2007031858A3 (en) An improved process for the preparation of beta-lactam antibiotic
AU2003297291A1 (en) Substituted arylcyclopropylacetamides as glucokinase activators
MXPA05013752A (es) Procedimiento e intermediarios para la preparacion de (1r,2s,5s)-6,6-dimetil-3-azabiciclo[3,1,0]exan-2-carboxilatos o sales de los mismos.
MY142423A (en) Substituted aminoacetyl pyrrolidine compounds which are dipeptidyl peptidase iv inhibitors, and pharmaceutical compositions containing them
AU2003282983A1 (en) Glycinenitrile-based inhibitors of dipeptidyl peptidase iv and methods
EP1406622A4 (en) DIPEPTIDYLPEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES
MXPA05010433A (es) Derivados de pirrolidina y procedimiento para prepararlos.
TW200801004A (en) Improved process for producing carbapenem compound
YU94103A (sh) Novi derivati sulfonske kiseline
MXPA05009688A (es) Derivados de naftiridina como agentes antibacterianos.
WO2002014313A3 (de) Neue beta-amyloid inhibitoren, verfahren zu deren herstellung und deren verwendung als arzneimittel
WO2002016322A3 (en) Process for the preparation of 2-aminoethylpyridines
MXPA03010548A (es) Proceso para el aislamiento de imipenem cristalino.
ATE518865T1 (de) Meropenem-zwischenprodukt in kristalliner form
MY134151A (en) Process for the preparation of crystalline n-formimindoyl thienamycin monohydrate (imipenem monohydrate)
AU2001262299A1 (en) New process for the preparation of vinyl-pyrrolidinone cephalosporine derivatives
TW360657B (en) Crystalline carbapenem derivative
MXPA03010498A (es) Proceso para la preparacion de imipenem.
NZ332453A (en) (1R,5S,6S)-6-[(1R)-1-hydroxyethyl]-1-methyl-2-[(2S,4S)-2-[(3R)-3-methylaminomethylpyrrolidin-1-ylcarbonyl]pyrrolidin-4-ylthio]-1-carbapen-2-em-3-carboxylic acid for the prevention or treatment of bacterial infections
AU2001225373A1 (en) Urea compounds as inhibitors for vla-4

Legal Events

Date Code Title Description
FG Grant or registration