EE200300206A - Kristalse N-formimidoüültienamütsiinmonohüdraadi (imipeneemmonohüdraadi) valmistamise meetod - Google Patents

Kristalse N-formimidoüültienamütsiinmonohüdraadi (imipeneemmonohüdraadi) valmistamise meetod

Info

Publication number
EE200300206A
EE200300206A EEP200300206A EEP200300206A EE200300206A EE 200300206 A EE200300206 A EE 200300206A EE P200300206 A EEP200300206 A EE P200300206A EE P200300206 A EEP200300206 A EE P200300206A EE 200300206 A EE200300206 A EE 200300206A
Authority
EE
Estonia
Prior art keywords
monohydrate
crystalline
preparation
formimidoylthienamycin
imipenem
Prior art date
Application number
EEP200300206A
Other languages
English (en)
Inventor
Kumar Yatendra
Tewari Neera
Chander Aryan Ram
Prakash Rai Bishwa
Ahuja Seema
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11097114&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE200300206(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of EE200300206A publication Critical patent/EE200300206A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
EEP200300206A 2000-11-03 2001-11-05 Kristalse N-formimidoüültienamütsiinmonohüdraadi (imipeneemmonohüdraadi) valmistamise meetod EE200300206A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN983DE2000 IN191798B (et) 2000-11-03 2000-11-03
PCT/IB2001/002069 WO2002036594A1 (en) 2000-11-03 2001-11-05 Process for the preparation of crystalline n-formimidoyl thienamycin monohydrate (imipenem monohydrate)

Publications (1)

Publication Number Publication Date
EE200300206A true EE200300206A (et) 2003-10-15

Family

ID=11097114

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300206A EE200300206A (et) 2000-11-03 2001-11-05 Kristalse N-formimidoüültienamütsiinmonohüdraadi (imipeneemmonohüdraadi) valmistamise meetod

Country Status (19)

Country Link
US (1) US7078534B2 (et)
EP (1) EP1334105B1 (et)
JP (1) JP2004525084A (et)
KR (1) KR20030059812A (et)
CN (1) CN100445284C (et)
AT (1) ATE322495T1 (et)
AU (1) AU2002212591A1 (et)
BG (1) BG107852A (et)
CA (1) CA2427762C (et)
DE (1) DE60118593D1 (et)
DK (1) DK1334105T3 (et)
EA (1) EA006442B1 (et)
EE (1) EE200300206A (et)
ES (1) ES2261494T3 (et)
IN (1) IN191798B (et)
MX (1) MXPA03003916A (et)
PT (1) PT1334105E (et)
WO (1) WO2002036594A1 (et)
ZA (1) ZA200303338B (et)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR036018A1 (es) * 2001-05-18 2004-08-04 Ranbaxy Lab Ltd Proceso para aislar monohidrato de imipenem cristalino puro
BR0209842A (pt) 2001-05-18 2005-01-04 Ranbaxy Lab Ltd Processo para a preparação de imipenem
NZ529625A (en) * 2001-05-18 2006-02-24 Ranbaxy Lab Ltd Process for the preparation of amorphous cilastatin sodium
WO2003016312A1 (fr) * 2001-08-13 2003-02-27 Eisai Co., Ltd. Procede de preparation d'antibiotiques a base de carbapenem
EA200400682A1 (ru) * 2001-11-16 2004-10-28 Рэнбакси Лабораториз Лимитед Способ получения кристаллического имипенема
US6537985B1 (en) 2001-11-30 2003-03-25 Phoenix Scientific, Inc. Antibiotic formulation and a method of making this formulation
CA2531578C (en) * 2003-12-09 2008-10-07 Choongwae Pharm. Co. A new process for preparation of imipenem
KR100848752B1 (ko) * 2006-11-10 2008-07-25 제일약품주식회사 티에나마이신 용매화합물 및 그의 제조방법
KR100848751B1 (ko) * 2006-11-10 2008-07-25 제일약품주식회사 이미페넴의 제조방법
WO2009047604A1 (en) * 2007-10-08 2009-04-16 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of carbapenem antibiotic
CN108623598A (zh) * 2018-05-21 2018-10-09 重庆天地药业有限责任公司 一种亚胺培南中间体及亚胺培南的制备方法
CN111413427A (zh) * 2020-04-08 2020-07-14 苏州和合医学检验有限公司 超滤前处理高效液相色谱测定血浆中亚胺培南含量的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4194047A (en) * 1975-11-21 1980-03-18 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin
US4260543A (en) * 1978-07-03 1981-04-07 Merck & Co., Inc. Crystalline N-formimidoyl thienamycin
JP3048196B2 (ja) 1991-06-20 2000-06-05 第一製薬株式会社 カルバペネム誘導体
AU667837B2 (en) 1991-10-01 1996-04-18 Procter & Gamble Pharmaceuticals, Inc. Process for making antimicrobial quinolonyl lactams
RU2070555C1 (ru) 1992-09-09 1996-12-20 Санкио Компани Лимитед Способ получения соединения пенема или карбапенема и соединение карбапенема
US5245069A (en) * 1992-10-27 1993-09-14 Merck & Co., Inc. Process for the preparation of bis(aryl)-phosphorohalidates
US5872250A (en) * 1997-07-30 1999-02-16 Merck & Co., Inc. Process for synthesizing carbapenem antibiotics

Also Published As

Publication number Publication date
KR20030059812A (ko) 2003-07-10
CN1481384A (zh) 2004-03-10
EA006442B1 (ru) 2005-12-29
ATE322495T1 (de) 2006-04-15
AU2002212591A1 (en) 2002-05-15
EP1334105B1 (en) 2006-04-05
EA200300520A1 (ru) 2003-10-30
MXPA03003916A (es) 2004-01-29
CA2427762A1 (en) 2002-05-10
EP1334105A1 (en) 2003-08-13
US7078534B2 (en) 2006-07-18
CN100445284C (zh) 2008-12-24
PT1334105E (pt) 2006-08-31
BG107852A (bg) 2004-01-30
IN191798B (et) 2004-01-03
WO2002036594A1 (en) 2002-05-10
DK1334105T3 (da) 2006-08-14
JP2004525084A (ja) 2004-08-19
ES2261494T3 (es) 2006-11-16
US20040054167A1 (en) 2004-03-18
DE60118593D1 (de) 2006-05-18
CA2427762C (en) 2009-10-20
ZA200303338B (en) 2004-03-09

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